Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3569 products of "Nucleosides"
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2'-Deoxycytidine-5'-O-monophosphorothioate sodium salt
CAS:2'-Deoxycytidine-5'-O-monophosphorothioate sodium salt is a nucleoside that is used in the synthesis of DNA. It is also an activator for the phosphoramidite group. This product has novel chemical properties and is CAS No. 63225-09-2. The purity of this product is high, and it can be used as a monophosphate or diphosphate. It has anticancer and anti-inflammatory activities, which are related to its antioxidant properties and ability to inhibit prostaglandin synthesis.
Formula:C9H14N3O6PSPurity:Min. 95%Molecular weight:323.26 g/mol5-[N(2-Trifluoroacetamido)ethyl)-3-(E)-acrylamido]-2-deoxyuridine
CAS:5-[N(2-Trifluoroacetamido)ethyl)-3-(E)-acrylamido]-2-deoxyuridine is an anticancer, antiviral, and phosphoramidite DNA synthesis reagent that is modified by the addition of a trifluoroacetamide group. It has been shown to activate monophosphate nucleotides and nucleosides to their corresponding diphosphates and deoxyribonucleosides. 5-[N(2-Trifluoroacetamido)ethyl]-3-(E)-acrylamido]-2-deoxyuridine is synthesized from 2-deoxyuridine which is derived from uracil and phenol. This novel chemical substance has shown promising results in preclinical testing against human cancers and viral infections.Formula:C16H19F3N4O7Purity:Min. 95%Molecular weight:436.34 g/mol2-Methylthio-6-chloropurine riboside
CAS:2-Methylthio-6-chloropurine riboside is an adenosine derivative that acts as a competitive inhibitor of the enzyme RNA polymerase. It is used in the process of translation to inhibit protein synthesis. 2-Methylthio-6-chloropurine riboside is synthesized by reacting 2-methylthioadenosine with 6-chloropurine riboside and then phosphoramidite chemistry.Formula:C12H15CIN4O5SPurity:Min. 95%Molecular weight:466.25 g/mol6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester
CAS:6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester is a fluorescence probe that can be used as a marker for biological samples. It is minimally toxic and stable in vitro, and can be used to measure the protein content of cells. This compound has been used in vitro methods to study the effects of environmental factors on cellular metabolism by measuring the amount of ATP in 3T3-L1 preadipocytes. 6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester has also been used to measure the effectiveness of wastewater treatment processes by analyzing the fluorescence intensity of cells using confocal microscopy. It has also been shown to have an effect on hypersensitivity syndrome and infectious diseases.Formula:C29H19NO11Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:557.46 g/mol1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione
CAS:1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione is a novel nucleoside that is synthesized from 5-(3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzyl)pyrimidine and dimethoxytrityl chloride. This compound has antiviral and anticancer properties. It can inhibit the replication of DNA by binding to the 3' hydroxyl group of the deoxyribonucleotide triphosphate. It also inhibits cancer cell growth by inhibiting RNA synthesis and protein synthesis. 1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3 , 2]dPurity:Min. 95%2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine
CAS:2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine is an antiviral drug that inhibits the synthesis of viral DNA and RNA. It is a synthetic nucleoside analogue with antiviral activity against herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein Barr virus, and human immunodeficiency virus type 1. This compound is also used as a building block in the preparation of phosphoramidites for chemical synthesis of deoxyribonucleosides. 2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine has shown anticancer activity in vitro and can be used to treat various types of cancer.Formula:C10H11F2N5O3Purity:Min. 95%Molecular weight:287.22 g/mol2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine
CAS:2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine is an activator, which is a substance that activates the enzymes that catalyze chemical reactions. It is a novel material with high purity and high quality. The activator can be used in the synthesis of ribonucleosides, deoxyribonucleosides, nucleosides, and phosphoramidites. 2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine has been found to have anticancer and antiviral activities.Purity:Min. 95%3-N-(2,4-Dimethylbenzyl)-1-(5-O-DMT-3-O-nitrophenylsulphonyl-2-deoxy-b-D-lyxofuranosyl)thymidine
CAS:3-N-(2,4-Dimethylbenzyl)-1-(5-O-DMT-3-O-nitrophenylsulphonyl-2-deoxy-b-D-lyxofuranosyl)thymidine is a modified nucleoside that has antiviral and anticancer properties. It is a synthetic nucleotide with a novel structure that can be phosphorylated to form the corresponding diphosphate, monophosphate, or phosphoramidites. 3N-(2,4-Dimethylbenzyl)-1-(5-O-DMT (3'-O-[(dimethylamino)methyl]oxime)-2'-deoxyribofuranosyl)thymidine is used as an antiviral agent against HIV and other retroviruses.Formula:C46H45N3O13SPurity:Min. 95%Molecular weight:879.93 g/mol2'-Deoxy-5'-O-p-toluenesulfonyluridine
CAS:2'-Deoxy-5'-O-p-toluenesulfonyluridine is a nucleoside that is modified with a p-toluenesulfonyl group on the 2' position. This compound has been shown to be an activator of phosphoramidites. It is also used as an anticancer drug, antiviral agent, and in the synthesis of ribonucleosides and deoxyribonucleosides. 2'-Deoxy-5'-O-p-toluenesulfonyluridine is typically used as a building block for RNA or DNA synthesis. This compound can also be used in the preparation of aminoglycoside antibiotics, as well as for the treatment of cancerous tumors.
Formula:C16H18N2O7SPurity:Min. 95%Molecular weight:382.4 g/mol5-(4-Hydroxybutyn-1-yl)uridine
CAS:5-(4-Hydroxybutyn-1-yl)uridine (5-BPU) is a nucleoside that inhibits viral replication. It is synthesized by the phosphoramidite method and modified to produce a 5-(4-hydroxybutyn-1-yl)uridine diphosphate (5-BPUDP). 5-BPUDP can be phosphorylated to form 5-(4-hydoxybutyn-1-yl)uridine monophosphate (5-BPUMP), which is more active than 5-(4-hydoxybutyn-1 -yl)uridine diphosphate. The antiviral activity of this drug has been demonstrated in vitro using human T lymphocytes, Epstein Barr virus, and herpes simplex virus type 1. It has also shown anticancer activity against leukemia cells in mice and rats.Formula:C13H16N2O7Purity:Min. 95%Molecular weight:312.28 g/mol(4-N,N-(Dipropyl-1,1-dichloro-2-)aminophenyl)(5'-deoxy-5'-glycylamino-2'-O-tetrahydropyranylcytidyl-3')hydrogen phosphate
The phosphoramidite monophosphate compound is a synthetic nucleotide analogue that has antiviral and anticancer properties. The chemical formula of the compound is (4-N,N-(Dipropyl-1,1-dichloro-2-)aminophenyl)(5'-deoxy-5'-glycylamino-2'-O-tetrahydropyranylcytidyl-3')hydrogen phosphate. This chemical can be used as a building block in DNA synthesis to produce deoxyribonucleosides and activate ribonucleoside phosphates to produce ribonucleosides. It has a CAS number of 90533-20-0.Formula:C26H37Cl2N6O9PPurity:Min. 95%Color and Shape:Pale yellow oilMolecular weight:679.49 g/mol5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine
CAS:5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine is a novel antiviral monophosphate nucleoside. It inhibits viral DNA synthesis by competing with natural deoxyribonucleosides in the cell. 5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine is a high purity, modified nucleoside that has been synthesized by chemical phosphoramidite chemistry and modified to allow for efficient polymerase chain reactions. This product has been tested as an anticancer agent in vitro.Formula:C33H36N4O6Purity:Min. 95%Molecular weight:584.66 g/molPseudoisocytidine hydrochloride
CAS:Pseudoisocytidine is a nucleoside analogue that inhibits bacterial growth by binding to the ribosomal RNA of bacteria. Pseudoisocytidine is synthesized from the reaction of isopropyl alcohol and furan, which produces a reactive intermediate (methyl ester) that can be labeled with an electron-deficient carbonyl group. The pseudoisocytidine molecule binds to the ribosome and prevents it from translating mRNA into protein. This leads to inhibition of bacterial growth. Pseudoisocytidine hydrochloride has been shown to have antibiotic activity against some Gram-positive bacteria, such as showdomycin resistant Staphylococcus aureus.
Formula:C9H13N3O5·HClPurity:Min. 95%Molecular weight:279.68 g/mol5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine
CAS:5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine is a novel monophosphate nucleotide activated with 2,4,6-trimethylphenyl (TMP) and used as a building block in the synthesis of oligonucleotides. The synthesized nucleoside can be converted to a diphosphate or phosphoramidite. 5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine is an anticancer agent that inhibits DNA synthesis by inhibiting ribonucleic acid (RNA) synthesis. It has been shown to inhibit the proliferation of human leukemia cells and may have potential for use in therapy for cancer treatment.Formula:C18H21FN2O5Purity:Min. 95%Molecular weight:364.4 g/mol2'-Deoxyuridine
CAS:Please enquire for more information about 2'-Deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C9H12N2O5Purity:Min. 98 Area-%Molecular weight:228.2 g/molRef: 3D-Q-200273
1kgTo inquire100gTo inquire250gTo inquire500gTo inquire2500gTo inquire-Unit-ggTo inquireN4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine
CAS:N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine is a nucleoside analog that is used as an antiviral and anticancer drug. It is also known to be an activator of the immune system. N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine has been shown to inhibit viral DNA replication, induce apoptosis, and inhibit tumor growth. The drug has shown potential in treating chronic hepatitis B virus infections, some types of cancer, and HIV/AIDS.Formula:C34H37N3O8Purity:Min. 95%Molecular weight:615.67 g/molAdenosine 5'-monophosphate sodium salt [1',2',3',4',5'-13C5]
Adenosine 5'-monophosphate sodium salt is a modified nucleoside that is used as an antiviral and an activator of the immune system. It also has been shown to have anti-inflammatory properties. Adenosine 5'-monophosphate sodium salt is synthesized by phosphoramidite chemistry and purified by HPLC. This product is a monophosphate form of adenosine, which is a nucleoside consisting of adenine attached to ribose sugar with a phosphate group at the 3' position. It can be used in DNA synthesis and modification, as well as RNA synthesis and modification.Purity:Min. 95%2'-Deoxy- N, N- dimethyl-adenosine
CAS:2'-Deoxy-N, N-Dimethyl-Adenosine is a nucleoside that is phosphorylated to 2'-deoxy-N, N-dimethyl-adenosyl monophosphate. It has antiviral and anticancer properties, and is synthesized by the reaction of deoxyadenosine phosphate and dimethylamine. This product is a novel nucleoside with modified phosphate groups. The synthesis of this nucleoside has been patented.
Formula:C12H17N5O3Purity:Min. 95%Molecular weight:279.3 g/molLamivudine 5'-monophosphate triethyammonium salt
Lamivudine is an antiviral medication that is used to treat HIV and Hepatitis B. It is also effective against a number of cancers, including leukemia and lymphoma. Lamivudine is a modified nucleoside with a ribonucleotide moiety linked by an ether bond to the 5'-hydroxyl group of deoxyribonucleosides. It acts as an inhibitor of viral reverse transcriptase, preventing the conversion of RNA into DNA and thus inhibiting the formation of viral DNA. Lamivudine has been shown to be active against a number of cancer cell lines, including leukemia cells and lymphoma cells. Lamivudine has also been shown to be an activator for diphosphate synthesis in vitro.Purity:Min. 95%2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite is a synthetic nucleoside. It inhibits DNA synthesis by competitive inhibition of the enzyme DNA polymerase. This compound is used in research to study the mechanism of action of anticancer drugs, novel antiviral agents, and other nucleic acid analogs. 2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite has been shown to be an activator that can stimulate ribonucleotide reductase and RNA polymerase in vitro.Purity:Min. 95%2'-Deoxy-2'-fluoro-arabinoisocytidine
CAS:2'-Deoxy-2'-fluoro-arabinoisocytidine is a nucleoside that is used in the synthesis of DNA and RNA. It is an activator for phosphoramidites, which are used in the preparation of modified oligonucleotides, such as those with modified bases or sugars. 2'-Deoxy-2'-fluoro-arabinoisocytidine has been shown to inhibit cancer cells, although it has not been studied as extensively as other anti-cancer drugs. This drug also inhibits the replication of human immunodeficiency virus (HIV) by inhibiting reverse transcriptase activity. 2'-Deoxy-2'-fluoro-arabinoisocytidine binds to viral DNA and prevents it from being copied into viral RNA. This nucleoside also has antiviral activity against herpes simplex virus type 1 (HSV1).Formula:C9H12FN3O4Purity:Min. 95%Molecular weight:245.21 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate
N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate is a nucleoside analog that inhibits DNA and RNA synthesis, as well as DNA replication. It is an antiviral agent that has been shown to have activity against herpes simplex virus type 1 (HSV1) and human cytomegalovirus (HCMV). N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate has also been found to be active against cancer cells in mice. The drug is synthesized by reacting the 5' - O - DMT - 2' - fluoro - cytidine with succinic acid, which is then converted to the desired product by adding a phosphoramidite. The final product contains high purity monophosphate ribonucleosides.Purity:Min. 95%N-Acetyl-5'-O-DMT-2'-O-[[[tris(1-methylethyl)silyl]oxy]methyl]-adenosine 3'-CE phosphoramidite
CAS:N-Acetyl-5'-O-DMT-2'-O-[[[tris(1-methylethyl)silyl]oxy]methyl]-adenosine 3'-CE phosphoramidite is a modified nucleoside with antiviral and antitumor activity. It is synthesized by modifying the ribonucleotide to an acetylated ribonucleotide. This compound is used in the synthesis of oligodeoxyribonucleotides as a synthetic DNA activator, antiretroviral agent, and anticancer agent. N-[5'-O-DMT-2'-O-[(tris(1-methylethyl)silyl]oxy]-methyl]-adenosine 3'-CE phosphoramidite has been shown to be effective against various types of human cancer cells in vitro, including prostate cancer cells.Formula:C52H72N7O9PSiPurity:Min. 95%Molecular weight:998.23 g/molN2-Isobutyryl-7'-OH-morpholino guanosine
CAS:N2-Isobutyryl-7'-OH-morpholino guanosine is a novel antiviral agent that has been shown to inhibit the production of viral nucleic acids. It is an analogue of deoxyguanosine, which is a natural nucleoside. The N2-isobutyryl moiety on 7'-OH-morpholino guanosine prevents the formation of 5'-monophosphate and 5'-diphosphate derivatives. This drug is activated by phosphoramidite chemistry to give high quality and high purity N2-isobutyryl-7'-OH-morpholino guanosine.Formula:C14H20N6O4Purity:Min. 95%Molecular weight:336.35 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine-3'-lcaa-CPG
N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine-3'-lcaa-CPG is an antiviral agent that inhibits the RNA polymerase of the virus. It is a phosphoramidite, which is a nucleoside with a phosphate group at the 5' position. N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine has been shown to be cytotoxic against cancer cells, and have less side effects than other nucleosides. It has been shown to selectively bind to ribonucleosides and deoxyribonucleosides and inhibit their synthesis by binding to the enzyme DNA polymerase. This stops DNA replication and causes cell death.Purity:Min. 95%α, β-Methyleneadenosine 5'-triphosphate trisodium
CAS:α, β-Methyleneadenosine 5'-triphosphate trisodium (MBATP) is an ester hydrochloride that is used as a pharmacological treatment for experimental models of cardiac, granule neurons and detrusor muscle. MBATP is also known to regulate the opening of voltage-dependent calcium channels in mesenteric artery smooth muscle cells. This drug has been shown to reduce the mitochondrial membrane potential and promote apoptosis in cardiac myocytes. Further studies have shown that MBATP binds to p2y receptors, which are involved in the regulation of physiological function. MBATP has been shown to inhibit the polymerase chain reaction (PCR), leading to reduced DNA synthesis and transcriptional activity. It also inhibits basic fibroblast growth factor expression by binding to the protein receptor tyrosine kinase c-kit, which may contribute to its effect on cell proliferation.Formula:C11H15N5Na3O12P3Purity:Min. 95%Molecular weight:571.15 g/mol2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt - 10 mM aqueous solution
CAS:2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt is a nucleotide analog that inhibits the synthesis of DNA. It inhibits transcription and replication of HIV. The compound is used for the treatment of HIV infection and is effective against tissue culture-grown virus. 2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt inhibits the activity of mammalian DNA polymerase and has been shown to inhibit the replication of HIV in tissue culture. It is also useful as a probe for studying dna replication, transcription, and recombination.Formula:C9H16N3O12P3S·xNaPurity:Min. 95%Molecular weight:483.22 g/mol2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite is a modified nucleotide that has been used in the synthesis of DNA. It is a monophosphate, diphosphate, and nucleoside. This compound has also been shown to be an activator for the ribonucleosides and deoxyribonucleosides. 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite has CAS number 55913-85-5.Formula:C43H54N7O7PPurity:Min. 95%Molecular weight:811.93 g/mol4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid monosodium salt
CAS:4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid monosodium salt is a nucleotide with phosphoramidite groups on the purine and pyrimidine rings. This compound has antiviral, anticancer and DNA synthesis inhibiting properties. It is also a novel nucleotide that can be used to synthesize modified nucleotides for use in DNA, RNA or protein synthesis.Formula:C23H28N7O6·NaPurity:Min. 95%Molecular weight:521.5 g/mol2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-2'-(2-methoxyethyl)guanosine
2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-2'-(2-methoxyethyl)guanosine is a nucleoside that is synthesized from deoxyribonucleosides. It has the following chemical structure:Purity:Min. 95%6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution
CAS:6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution is a modified nucleoside that is used as an activator in the synthesis of DNA and RNA. 6-Methylthioguanosine-5’- triphosphate sodium salt - 10 mM aqueous solution can be used to synthesize ribonucleosides, deoxyribonucleosides and phosphoramidites. It has antiviral properties, which may be due to its ability to inhibit viral polymerase by competitively binding to the enzyme's active site. 6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution also has anticancer effects and is able to induce apoptosis in cancer cells.Formula:C11H18N5O13P3S·xNaPurity:Min. 95%Molecular weight:553.27 g/mol3'-Deoxy-5-methyluridine
CAS:3'-Deoxy-5-methyluridine (3'-DMAU) is a synthetic nucleoside that is used in the treatment of viral infections. 3'-DMAU has antiviral and anticancer activity, and it has been used to synthesize DNA for genetic engineering. It has shown promising results in the treatment of HIV as well as in the prevention of cancer metastasis. 3'-DMAU inhibits DNA synthesis by binding to the enzyme RNA polymerase, which blocks its interaction with ribonucleosides, thus inhibiting RNA synthesis. In addition, 3'-DMAU causes cell death by inhibiting protein synthesis. The drug is activated by phosphorylation to form 5'-triphosphate and 5'-diphosphate derivatives, which inhibit DNA and RNA synthesis at multiple sites within the cell.Formula:C10H14N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:242.23 g/mol2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite
CAS:2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite is a fluorescent DNA probe that can be used for the detection of specific sequence mismatches in target DNA. This probe contains a linker, which is a short oligonucleotide, and a fluorescent label at the 5' end. The probe has been designed to hybridize to its complementary sequence in the target DNA. When it detects mismatches, it becomes fluorescent because of increased stacking interactions between the bases. This allows for easy detection of mismatches in target sequences without the need for PCR amplification or gel electrophoresis.Formula:C42H53N6O7PPurity:Min. 95%Color and Shape:PowderMolecular weight:784.88 g/molUridine diphosphate choline (UDPC) sodium
CAS:Uridine diphosphate choline (UDPC) sodium is a nucleotide that is used as a phosphoramidite for DNA synthesis. The chemical formula for UDPC is C8H14N4O8P. The activation of the molecule occurs in acidic conditions, which may be due to the formation of an amide bond between the terminal phosphate and the amino group on the phosphorylcholine. This same reaction can also occur in alkaline conditions. UDPC has been shown to inhibit viral replication, including HIV-1, by blocking reverse transcription of viral RNA into DNA. It also has anticancer effects, as it inhibits cell proliferation and induces apoptosis in cancer cells. UDPC does not have any known side effects or toxicity.Formula:C14H25N3O12P2•NaPurity:Min. 95%Color and Shape:PowderMolecular weight:512.3 g/molN6-Benzoyl-3'-deoxy-3'-fluoroadenosine
CAS:N6-Benzoyl-3'-deoxy-3'-fluoroadenosine is a nucleoside analog that is structurally similar to adenosine. It has antiviral and anticancer properties and can be used in the treatment of HIV and other viral infections. N6-Benzoyl-3'-deoxy-3'-fluoroadenosine inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase, which is required for DNA replication. This drug also binds to RNA polymerase, which is an enzyme required for RNA synthesis. N6-Benzoyl-3'-deoxy-3'-fluoroadenosine has been shown to have a high level of efficacy against leukemia cells in vitro as well as in vivo mouse models.Purity:Min. 95%Guanosine-5'-[(a,beta)-methyleno]triphosphate sodium salt
CAS:Guanosine-5'-[(a,b)-methyleno]triphosphate sodium salt (GpCpp) is a non hydrolyzable nucleosidePurity:Min. 95%2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine
CAS:2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine is a novel and synthetic nucleoside analog with antiviral activity. It inhibits the synthesis of DNA by binding to the enzyme ribonucleotide reductase. This compound has been shown to be an activator of PPARs in vitro.Formula:C21H38N2O6Si2Purity:Min. 95%Molecular weight:470.72 g/mol(-)-Emtricitabine triphosphate sodium salt
CAS:Emtricitabine is a nucleoside reverse transcriptase inhibitor with activity against human immunodeficiency virus and hepatitis B virusFormula:C8H9FN3Na4O12P3SPurity:Min. 95%Molecular weight:575.11 g/molAdenosine 3'-monophosphate sodium
CAS:Adenosine 3'-monophosphate sodium is a nucleotide that is used as a substrate for enzymes. It has been shown to increase the enzymatic activity of papaverine, litoralis, subtilis, and histidine phosphatase. Adenosine 3'-monophosphate sodium also has protease activity, which can be activated by adding an enzyme preparation containing subtilisin and trypsin. This compound also has a pH optimum of 8.0-9.5 and is active at an alkaline pH of 9.5-10.5. The specific strain of bacteria will determine the optimal pH range for activity, with enterobacter bacterial strains having a maximum range of 6-7 and brevibacterium bacteria strains having a range of 4-6.Formula:C10H12N5O7PNa2Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:391.19 g/mol2'-O-(2-Methoxyethyl)adenosine 5'-α-thiotriphosphate sodium
2'-O-(2-Methoxyethyl)adenosine 5'-a-thiotriphosphate sodium salt is a synthetic nucleoside with antiviral and anticancer properties. It is an analog of adenosine 5'-triphosphate (ATP) in which the ribose sugar has been replaced by a 2'-O-(methoxyethyl) moiety. It has shown to be cytotoxic against cancer cells, and it is a potent activator of human telomerase, the enzyme that synthesizes telomeres at the end of chromosomes. This compound has been shown to have high purity and quality and does not have any CAS numbers assigned to it.Formula:C13H18N5Na4O13P3SPurity:Min. 95%Molecular weight:669.25 g/molThymidine-3',5'-diphosphate disodium salt
CAS:Thymidine-3',5'-diphosphate disodium salt is an antiviral and anticancer drug. It is a modified nucleoside which is synthesized from thymidine-3',5'-diphosphate and sodium bicarbonate (NaHCO3). This drug inhibits the synthesis of DNA and RNA, thereby inhibiting viral replication. Thymidine-3',5'-diphosphate disodium salt also has an antitumor effect by preventing the production of DNA in tumor cells.Formula:C10H14N2Na2O11P2Purity:Min. 95%Color and Shape:PowderMolecular weight:446.15 g/molN6-(6-Aminohexyl)-2'-deoxyadenosine
CAS:N6-(6-Aminohexyl)-2'-deoxyadenosine is a novel nucleoside that is structurally related to the natural nucleosides, dATP and dGTP. It has been shown to be an activator of ribonucleosides and phosphoramidites, which are used in the synthesis of DNA and RNA. N6-(6-Aminohexyl)-2'-deoxyadenosine has also been shown to inhibit cancer cells as well as antiviral activity against HIV-1.Formula:C16H26N6O3Purity:Min. 95%Color and Shape:Slightly Yellow PowderMolecular weight:350.43 g/mol5-Methoxyuridine-5'-triphosphate sodium, 100mM aqueous solution
CAS:5-Methoxyuridine-5'-triphosphate is a monophosphate nucleoside that serves as a precursor for the synthesis of 5-methoxyuridine (5MU) and other nucleosides. It has antiviral effects, and is used in the treatment of herpes zoster infection. 5-Methoxyuridine-5'-triphosphate is an analog of uridine and deoxyribonucleosides with antiviral activity, which can be used to treat herpes zoster infection. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis by inhibiting ribonucleotide reductase and DNA polymerase, leading to cell death.Formula:C10H17N2O16P3•NaxPurity:Min. 95%Color and Shape:Clear LiquidMolecular weight:514.17 g/molN6-Methyl-N6-threonylcarbamoyladenosine
CAS:N-(N'-Methyl-N-(9 beta-D-ribofuranosylpurin-6-yl)carbamyl)threonine is a nucleoside that is used in research.Formula:C16H22N6O8Purity:Min. 95%Molecular weight:426.38 g/molDMT-2′O-TC-rG(ib) Phosphoramidite
CAS:DMT-2²O-TC-rG(ib) Phosphoramidite is a phosphoramidite that has been modified from the natural nucleoside DMT. It is a high purity, novel anticancer agent that has shown promising results in the treatment of cancer cells. The modifications on the phosphate group allow for enhanced phosphorylation which, in turn, leads to an increase in kinase activity. This modification also increases the stability of DNA and RNA synthesis, as well as protein synthesis.Formula:C49H61N8O11PS2Purity:Min. 95%Color and Shape:PowderMolecular weight:1,033.16 g/mol2-Deoxy-5'-O-DMT-N2-isobutyryl-8-oxoguanosine 3'-CE phosphoramidite
CAS:2-Deoxy-5'-O-DMT-N2-isobutyryl-8-oxoguanosine 3'-CE phosphoramidite is an 8-oxo modified amidite. The 8-oxo modification is caused naturally in DNA by oxidation so is significant in mutagenesis and ultimately carcinogenesis.Formula:C44H54N7O9PPurity:Min. 95%Molecular weight:855.94 g/mol1-b-D-Arabinofuranosyluracil 5'-monophosphate
CAS:1-b-D-Arabinofuranosyluracil 5'-monophosphate is a pyrimidine nucleotide analog. Because of its structural similarity to natural nucleotides, it can interact with enzymes involved in nucleic acid synthesis. It is also a metabolite of Ara-U (arabinosyluracil), which is itself a compound studied for its biological activity. Scientists could potentially use this molecule in research to study how cells process and use nucleotides, and to understand how changes in nucleotide structure can affect biological processes.Formula:C9H13N2O9PPurity:Min. 95%Color and Shape:PowderMolecular weight:324.18 g/mol2-Phenylaminoadenosine
CAS:2-Phenylaminoadenosine (2-PA) is a potent and selective inhibitor of the P2Y receptor. 2-PA has been shown to reduce myocardial infarct size in vivo in mice, which may be due to its ability to inhibit the release of dopamine from the brain. In addition, 2-PA binds to LPS receptors on endothelial cells, reducing the production of proinflammatory cytokines and preventing platelet aggregation. 2-PA also inhibits the activation of toll-like receptor 4 (TLR4) in human monocytes, leading to reduced expression of proinflammatory cytokines and increased expression of anti-inflammatory cytokines. 2-PA is an agonist that binds with high affinity to P2Y receptors on erythrocytes. This binding results in decreased adenosine triphosphate (ATP) production by adenosine deaminase, which leads to decreased intracellular calcium levels and inhibition of neutrophFormula:C16H18N6O4Purity:Min. 95%Color and Shape:PowderMolecular weight:358.35 g/mol8-Amino-2’-deoxyadenosine
CAS:8-Amino-2’-deoxyadenosine (8AAD) is a nucleoside that is used in the laboratory for the analysis of dna duplexes. It stabilizes dna duplexes in an acidic environment, and it can be used to analyze the stability of dna duplexes at neutral pH. 8AAD can also stabilize triplex structures formed by 8AAD, amines, and purines. The orientation of these bases in the triplex structure is important because they can determine which strands are cleaved during hydrolysis.Formula:C10H14N6O3Purity:Min. 95%Molecular weight:266.26 g/mol1-(β-D-Arabinofuranosyl)-5-hydroxymethyluracil
CAS:A hetero-base functionalised ara-nucleosideFormula:C10H14N2O7Purity:Min. 95%Molecular weight:274.23 g/mol8-Aza-7-deaza-2'-deoxyguanosine
CAS:8-Aza-7-deaza-2'-deoxyguanosine is an alkynylated, cross-linked, single stranded nucleic acid. It has been shown to be effective at cross-linking and cross-linking nucleic acids. 8-Aza-7-deaza-2'-deoxyguanosine binds to the 7 deazapurine residues in DNA, forming a covalent bond between the two strands of the helix. This binding prevents the strand from unwinding and prevents the replication of DNA. The thermodynamic data for this compound shows that it is stable in both hot and cold water, which makes it a good candidate for use in research as well as in clinical settings.Formula:C10H13N5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:267.24 g/molN6-Benzoyl-L-adenosine
CAS:N6-Benzoyl-L-adenosine is a novel nucleoside that has been shown to have antiviral and anticancer activity. It is synthesized by the reaction of L-adenosine with benzoyl chloride in the presence of a base. The drug inhibits the growth of cancer cells by interfering with DNA synthesis. N6-Benzoyl-L-adenosine also inhibits viral replication, especially HIV, herpes simplex virus type 1, and human cytomegalovirus (HCMV). It can be used as an antiviral agent in combination with other drugs or as an anticancer agent alone. N6 Benzoyl L adenosine is a nucleoside that has been shown to have antiviral and anticancer activity. It is synthesized by the reaction of L adenosine with benzoyl chloride in the presence of a base. The drug inhibits the growth of cancer cells by interfering with DNA synthesis. N6Formula:C17H17N5O5Purity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:371.35 g/molm-Methoxytopolin riboside
CAS:m-Methoxytopolin riboside is a nucleoside that is a phosphoramidite derivative of the natural nucleoside, topolin riboside. This compound has antiviral and anticancer activities. It inhibits viral DNA synthesis and also induces apoptosis in cancer cells. m-Methoxytopolin riboside is modified with a methoxy group at the 3' position of the sugar moiety. This modification prevents incorporation into DNA and RNA, thereby inhibiting viral replication and inducing apoptosis in cancer cells.Formula:C18H21N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:387.39 g/mol3'-Phosphoadenosine-5'-phosphosulfate lithium salt hydrate
CAS:Universal sulfonate donor for in vivo sulfonation by sulfotransferasesFormula:C10H15N5O13P2S·xLi·yH2OPurity:Min. 60 Area-%Color and Shape:White PowderMolecular weight:507.27 g/mol2'-Amino-2'-deoxycytidine
CAS:2'-Amino-2'-deoxycytidine is a modified nucleoside, based on cytidine. In this compound 2'-hydroxyl group has been replaced by an amino group, which can change hydrogen bonding patterns potentially affecting how it interacts with biomolecules.Formula:C9H14N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:242.24 g/mol[(2S,6R)-6-{Thymin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:[(2S,6R)-6-{Thymin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate (TMP) is a Ribonucleoside and Deoxyribonucleoside Activator that is synthesized from Thymine (T), Thymidine (Td), and Phosphoramidites. TMP is a novel synthetic derivative of thymine with the ability to activate DNA synthesis reactions. TMP has been shown to provide high quality nucleotides with high purity in a single step reaction.Formula:C31H34ClN4O5PPurity:Min. 95%Color and Shape:White To Light (Or Pale) Red SolidMolecular weight:609.05 g/molN2-Isobutyryl-O6-(4-pivaloyloxybenzyl)-7’-OH-N-trityl-morpholino guanine
CAS:N2-Isobutyryl-O6-(4-pivaloyloxybenzyl)-7’-OH-N-trityl-morpholino guanine is a phosphoramidite nucleoside that is used as a building block in the synthesis of oligonucleotides. N2-Isobutyrylguanosine is available as a high purity, high quality, and novel nucleoside that can be used in anticancer therapy. It has been shown to inhibit the growth of human cancer cells without affecting normal cells. This drug also inhibits DNA and RNA synthesis by inhibiting the enzyme ribonucleotide reductase.Purity:Min. 95%ATP-acetyl-desthiobiotin
ATP-acetyl-desthiobiotin is a small molecule that inhibits the activity of tyrosine kinases. It has been shown to inhibit tumor growth in cultured cells and in mouse models, and is currently being evaluated in clinical trials for cancer treatment. ATP-acetyl-desthiobiotin is a competitive inhibitor of bosutinib (BST), an inhibitor of Bcr-Abl tyrosine kinase, which is associated with chronic myeloid leukemia. ATP-acetyl-desthiobiotin has also been shown to induce autophagy and inhibit cell proliferation, making it a potential anticancer drug.
Formula:C20H32N7O15P3Purity:Min. 95%Molecular weight:703.43 g/molKinetin riboside-5'-monophosphate sodium salt
CAS:Kinetin riboside-5'-monophosphate sodium salt is a synthetic nucleotide that has been modified to include a phosphate group at the 5' position. Kinetin riboside-5'-monophosphate sodium salt is an activator of DNA synthesis and can be used for the treatment of viral infections. It also shows anticancer activity and is effective against cancer cells that are resistant to other cancer drugs.Formula:C15H16N5Na2O8P·H2OPurity:Min. 95%Color and Shape:PowderMolecular weight:489.29 g/molN4-Acetyl-2'-O-tert-butyldimethylsilylcytidine
CAS:N4-Acetyl-2'-O-tert-butyldimethylsilylcytidine is a novel nucleoside that has been extensively studied for its anticancer and antiviral properties. It is a modified nucleoside that inhibits the production of DNA, RNA, and protein. This product is also used as an activator in the synthesis of oligonucleotides. N4-Acetyl-2'-O-tert-butyldimethylsilylcytidine can be used in vitro to study the effects of different cancer cells on DNA replication. It has been shown to inhibit the growth of human leukemia cells in culture.Formula:C17H29N3O6SiPurity:Min. 95%Color and Shape:PowderMolecular weight:399.51 g/mol5'-Biotin phosphoramidite
CAS:Biotin phosphoramidite is a biotin-containing compound that is used as an extracellular probe for bacterial cells. It can be used to permeabilize cells, and it has been shown to have cytosolic uptake in various cell types. Biotin phosphoramidite binds to peptidoglycan in the cytosol of bacterial cells, and this binding induces internalization. This compound also has the ability to bind to peptidoglycan in the cytosol of eukaryotic cells, but does not induce internalization. Experiments with vibrio parahaemolyticus suggest that biotin phosphoramidite is a marginally effective inhibitor of this organism's uptake of unmodified peptidoglycan.Formula:C46H64N5O6PSPurity:Min. 95%Molecular weight:846.07 g/molAdenosine 2',3'-cyclic monophosphate
CAS:Adenosine 2',3'-cyclic monophosphate triethylammonium salt (AMP-TEA) is a structural analogue of adenosine. It is a potent inhibitor of protein synthesis by preventing the phosphodiesterase activity of cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase. AMP-TEA can be used as a tool to study translation in tissue culture, as well as to examine the effects on protein synthesis and other biochemical reactions that are regulated by cyclic nucleotides. It is also used for the preparation of tissue samples for enzymatic analysis or for radiolabeling experiments. AMP-TEA has an optimum pH of 4.5, but can be used at lower or higher pH values. The optimal temperature range for use is between 0°C and 50°C, with the maximum stability occurring at 37°C.Formula:C10H12N5O6PPurity:Min. 95%Color and Shape:PowderMolecular weight:329.21 g/mol5-Aminoallyl uridine 5'-triphosphate sodium salt
CAS:5-Aminoallyl uridine 5'-triphosphate sodium salt is used in Nucleic Acid Sequence Based Amplification or RNA labelling.Formula:C12H20N3O15P3·xNaPurity:Min. 95%Molecular weight:539.22 g/molO1-(Dimethoxytrityl)propane-1,3-diol
CAS:Please enquire for more information about O1-(Dimethoxytrityl)propane-1,3-diol including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C24H26O4Purity:Min. 95%Molecular weight:378.5 g/mol2'-Deoxy-3,4,5,6-tetrahydrouridine
CAS:2'-Deoxy-3,4,5,6-tetrahydrouridine (2DTHR) is a cytidine deaminase inhibitor that is used in vitro to inhibit the production of tumor necrosis factor (TNF). 2DTHR has been shown to be active against hepatocellular carcinoma cells. It is also reactive with tumor tissue and can be eliminated at a rate similar to that of deoxycytidine kinase. This drug binds to the enzyme target and inhibits its activity by increasing enzyme levels, which causes cell death. 2DTHR inhibits TNF production in tumor tissue by binding to cytidine deaminase and preventing conversion of cytidine into uracil. This drug has been shown to cause tumor inhibition in vitro.
Formula:C9H16N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:232.23 g/molLamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution
Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution is an antiviral drug used to treat HIV/AIDS and hepatitis B infections. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication, acting by blocking the viral enzyme reverse transcriptase. Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution also inhibits cellular viral DNA synthesis and has been shown to exhibit anticancer activity in vitro and in vivo. This product is synthesized from raw materials through a novel process that involves modification of the phosphoramidite monophosphate with tetratriethylammonium salts.Formula:C32H74N7O12P3SPurity:Min. 95%Molecular weight:873.96 g/molPropionyl coenzyme A lithium salt
CAS:Propionyl coenzyme A lithium salt is a phosphoramidite that can be used in the synthesis of DNA and RNA. It is a novel chemical compound that has been modified to include ribonucleosides in addition to deoxyribonucleosides. This product is of high purity and quality, with a CAS number of 108321-21-7.
Formula:C24H40N7O17P3S·xLiPurity:85%Color and Shape:White PowderMolecular weight:823.6 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-8-oxoadenosine 3'-CE phosphoramidite
CAS:N6-Benzoyl-2'-deoxy-5'-O-DMT-8-oxoadenosine 3'-CE phosphoramidite is an 8-oxo modified amiditeFormula:C47H52N7O8PPurity:Min. 95%Molecular weight:873.95 g/molAdenylyl-3'-5'-guanosine sodium salt
CAS:3'-Adenylyl-5'-guanosine ammonium salt is a dinucleoside that competes with guanosine for binding to the enzyme adenylate cyclase. This reaction leads to increased levels of cyclic AMP, which causes an increase in the rate of viral replication. 3'-Adenylyl-5'-guanosine ammonium salt has been shown to inhibit the growth of pyogenic bacteria such as Streptococcus pyogenes and has also been used to treat influenza infections. 3'-Adenylyl-5'-guanosine ammonium salt is an inorganic compound that is found in tobacco. It can be synthesized from uridine and p-nitrophenyl phosphate by the reaction: 3'--O--(CH2)4--COOH + H2N--PO4--> 3'--O--(CH2)4--CONH2 + H3PO4
Formula:C20H24N10O11P·NaPurity:Min. 95%Molecular weight:634.43 g/mol6-Azauridine-5'-monophosphate sodium
CAS:Please enquire for more information about 6-Azauridine-5'-monophosphate sodium including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C8H12N3O9P•(Na)2Molecular weight:371.17 g/molFludarabine phosphate
CAS:Fludarabine phosphate is an antileukemic drug that inhibits DNA polymerase α and β, as well as other enzymes in the nucleotide synthesis pathway. It is used to treat patients with chronic myelogenous leukemia (CML) who have developed resistance to other treatments. Fludarabine phosphate has been shown to induce a cytotoxic effect against tumor cells by binding to ATP-binding cassette transporter proteins on the cell membrane and inhibiting intracellular targets such as DNA, RNA, and protein synthesis. Fludarabine phosphate has also been shown to inhibit the growth of tumor cells through synergistic interactions with other anticancer drugs such as hydroxyurea or busulfan, which may be due to its ability to inhibit enzyme activities such as erythrocyte alkaline phosphatase.
Formula:C10H13FN5O7PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:365.21 g/molN6-Benzyladenosine 5'-diphosphate sodium salt - 10 mM aqueous solution
CAS:N6-Benzyladenosine 5'-diphosphate sodium salt is a modified nucleoside that has a high purity, which is suitable for synthesis of DNA or RNA. It can be used in the modification of deoxyribonucleosides, ribonucleosides, and phosphoramidites. N6-Benzyladenosine 5'-diphosphate sodium salt has been shown to have anticancer effects and antiviral effects. This drug also has novel properties such as an ability to inhibit the proliferation of cancer cells.Formula:C17H21N5O10P2Purity:Min. 95%Color and Shape:Colorless PowderMolecular weight:517.32 g/molN6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite
CAS:N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite is a nucleoside phosphoramidite used as a building block in the chemical synthesis of oligonucleotides containing a 2’-O-methyl adenosine nucleoside unit. The use of a chemical synthesis rather than an enzymatic one allows oligonucleotides of a desired sequence to be produced. 3’-Cyanoethyl phosphoramidites are typically used by substitution of the di-isopropylamine group with an appropriate alcohol in the presence of an azole catalyst. Oligonucleotides containing 2'-O-methylribonucleoside units have shown site-specific cleavage with E. coli RNase H, either at a hairpin loop or at a stem region.Formula:C48H54N7O8PPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:887.98 g/mol3-Acetylpyridine adenine dinucleotide disodium, reduced form
CAS:Reduced synthetic analog of NADH with an acetylpyridine modification. It is used as a reducing substrate to study the mechanisms of NAD(P)+-dependent reductases and to probe the active sites and catalytic processes of these important enzymes through its altered spectroscopic and binding properties. The disodium salt ensures good solubility for biochemical applications.Formula:C22H30N6O14P2•Na2Purity:Min. 95%Color and Shape:Slightly Yellow PowderMolecular weight:710.43 g/molUridine 5'-triphosphate tris salt
CAS:Uridine 5'-triphosphate tris salt is a pyrimidine nucleotide that is used in the synthesis of RNA. It has been shown to be an effective inhibitor of hamster ovary and human ovarian cells. Uridine 5'-triphosphate tris salt is water-soluble and does not interfere with cellular assays or microfluidic devices. Uridine 5'-triphosphate tris salt has also been shown to have potential as a model system for analytical chemistry and pharmacological research.Formula:C13H26N3O18P3Purity:Min. 95%Color and Shape:White PowderMolecular weight:484.14 g/mol3'-Deoxyadenosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:3'-Deoxyadenosine-5'-triphosphate sodium salt is a nucleotide that has been shown to be effective in chemotherapy. It is a substrate for the synthesis of DNA, RNA, and ATP. 3'-Deoxyadenosine-5'-triphosphate sodium salt is also a building block for DNA polymerase, which is an enzyme that synthesizes DNA from a template. It has been shown to have anticancer activity in drug-resistant cells and can be used as an alternative to purine analogs such as 6-mercaptopurine or cladribine. 3'-Deoxyadenosine-5'-triphosphate sodium salt has been shown to inhibit the production of nucleotides by blocking their conversion into triphosphates, which are necessary for DNA replication and repair. This inhibition leads to apoptosis in cells with high levels of nucleotide turnover such as cardiac and myeloid cells. The drug interactions may depend on theFormula:C10H16N5O12P3Purity:Min. 95%Color and Shape:Colorless PowderMolecular weight:491.18 g/molMorpholino A monomer
CAS:Morpholino A is a modified nucleoside amidite used to prepare morpholino oligomersFormula:C38H37ClN7O4PPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:722.17 g/molPolyadenylic acid potassium
CAS:Please enquire for more information about Polyadenylic acid potassium including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:(C10H14N5O7P)x•KxPurity:85% Min2'-Deoxyinosine-5'-triphosphate sodium,100mM aqueous solution
CAS:2'-Deoxyinosine-5'-triphosphate sodium (2'-dITP) is a modified nucleotide that has antiviral and anticancer properties. It has been shown to be an activator for ribonucleosides, deoxyribonucleosides, and DNA. 2'-DITP has also been shown to inhibit the growth of human breast cancer cells in vitro.
Formula:C10H11N4Na4O13P3Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:580.09 g/mol2-Chloroadenosine
CAS:2-Chloroinosine is an adenosine receptor agonist; metabolically stable analog of adenosineFormula:C10H12ClN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:301.69 g/mol7-Deaza-2',3'-dideoxy-7-iodoadenosine
CAS:7-Deaza-2',3'-dideoxy-7-iodoadenosine is a nucleoside analogue that is used as an antiviral, anticancer, and antifungal agent. It is a modified form of adenosine which inhibits viral replication by inhibiting the activity of reverse transcriptase. 7-Deaza-2',3'-dideoxy-7-iodoadenosine has also been shown to inhibit DNA synthesis in cells by blocking the incorporation of dCTP into DNA. This nucleoside analogue has shown potential for use as an activator in phosphoramidite chemistry and as a deoxyribonucleoside in oligonucleotide synthesis.Formula:C11H13IN4O2Purity:Min. 95%Color and Shape:PowderMolecular weight:360.15 g/molm-Topolin riboside
CAS:Functionalised adenosine ribosideFormula:C17H19N5O5Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:373.36 g/mol7-deaza-dG-CE Phosphoramidite
CAS:7-deaza-dG-CE Phosphoramidite is a monophosphate nucleotide, which is synthesized by modification of the 7-deaza-dG ribonucleoside. It has an antiviral and anticancer activity, and is used as a building block for novel drugs. 7-Deaza-dG-CE phosphoramidite has been shown to inhibit tumor growth and induce apoptosis in Hep2 cells. It also inhibits HIV replication in vitro. The compound is chemically stable and does not react with other biomolecules.Formula:C44H54N7O7PPurity:Min. 95%Molecular weight:823.9 g/molCytidine-5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS:Cytidine-5'-O-(1-thiotriphosphate) lithium salt is a monophosphate nucleotide analog. It is soluble in water, and is used in the synthesis of DNA and RNA. Cytidine-5'-O-(1-thiotriphosphate) lithium salt has antiviral, anticancer, and anti-inflammatory properties. This compound can be used as an activator for phosphoramidites in the synthesis of DNA or RNA. Cytidine-5'-O-(1-thiotriphosphate) lithium salt is a novel nucleoside that can be used in the synthesis of modified oligonucleotides.Formula:C9H16N3O13P3S·xLiPurity:Min. 95%Molecular weight:499.22 g/mol5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å
5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å is a synthetic nucleoside that contains an acetyl group at the 5' position. The succinyl group has been added to the 3' position of the nucleoside and is bonded to a carrier molecule (2000 Å). This product is used as an activator in DNA synthesis, it also has antiviral and anticancer activities.Color and Shape:PowderThymidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:Thymidine-5'-triphosphate sodium salt is a modified nucleoside with anticancer properties. It is a high-quality, high-purity ribonucleoside that can be used as an activator for the synthesis of deoxyribonucleosides and phosphoramidites. Thymidine-5'-triphosphate sodium salt has antiviral activity, which is due to its ability to inhibit viral DNA replication and transcription. This compound also has the potential to be used in the treatment of cancer cells by inhibiting DNA synthesis and cell division.Formula:C10H17N2O14P3·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:482.17 g/mol2-Fluoroadenosine
CAS:2-Fluoroadenosine is a nucleoside that has shown high resistance to the enzyme cyclase. This property may be due to its structural and conformational properties, which are different from those of adenosine. 2-Fluoroadenosine has been shown to inhibit the synthesis of ATP in ventricular myocardium and fat cells, as well as increase levels of adenylate kinase in blood. It has also been shown to have potential as a drug target for autoimmune diseases, such as multiple sclerosis. 2-Fluoroadenosine can be used for biochemical and pharmacokinetic studies because it is rapidly metabolized by the liver and excreted in urine.
2-Fluoroadenosine can also be used to measure changes in the ratio of adenylate kinase:adenylate kinase reductase (AKAR) in blood plasma.Formula:C10H12FN5O4Purity:Min. 95%Color and Shape:White Slightly Yellow PowderMolecular weight:285.23 g/mol2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine
CAS:2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine is an analog of the nucleoside uridine. It is a potent inhibitor of protein synthesis in cells, and has the potential to be used as a long-term treatment for tuberculosis. 2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) in mice with influenza or hepatitis, and also inhibits the replication of HIV. This drug may also have antibacterial properties due to its ability to inhibit bacterial DNA gyrase and topoisomerase IV. 2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine binds to an antigen on the surface of cells, activating them.Formula:C20H26N7O10PSPurity:Min. 95%Molecular weight:587.5 g/mol9-(β-D-Arabinofuranosyl)adenine 5'-monophosphate
CAS:9-(β-D-Arabinofuranosyl)adenine 5'-monophosphate (Ara-AMP) is a prodrug that is converted to adenine arabinoside in vivo. It is used as an antiviral agent for the prevention of hepatitis B and C. Ara-AMP inhibits viral DNA synthesis by acting as a competitive inhibitor of adenosine triphosphate, which is required for viral DNA polymerase activity. Ara-AMP also has antiviral properties against some RNA viruses, such as HIV and influenza virus. Ara-AMP can be administered orally or by injection, making it suitable for use in children who are unable to take oral medication.Formula:C10H14N5O7PPurity:Min. 95%Color and Shape:White PowderMolecular weight:347.22 g/molN6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution
CAS:N6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an analog of adenosine triphosphate (ATP). It is used in the study of protein kinase C. ATP and its analogs are able to phosphorylate proteins and regulate their activity. This study has shown that N6-benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an atp analog that activates protein kinase C, leading to the phosphorylation of proteins. This analog also inhibits tyrosine kinases, which may be due to its ability to inhibit the reuptake of serotonin and other transmitters.Formula:C17H22N5O13P3·xNaPurity:Min. 95%Color and Shape:Colorless PowderMolecular weight:597.3 g/molent-abacavir
CAS:Ent-abacavir is a drug that belongs to the group of antiretroviral drugs. It has minimal toxicity and has been shown to be effective in long-term treatment of HIV/AIDS. Ent-abacavir is also used as part of active antiretroviral therapy, which includes at least three or four different drugs. It inhibits the activity of reverse transcriptase, an enzyme involved in the replication process of HIV and other retroviruses. This drug has been shown to have few drug interactions with other medications, although caution should be taken when using ent-abacavir with drugs that are metabolized by cytochrome P450 enzymes. Ent-abacavir is not recommended for use in patients who have chronic viral hepatitis or who have a body mass index greater than 30 kg/m2 because its pharmacokinetic properties may be altered in these individuals.Formula:C14H18N6OPurity:Min. 95%Molecular weight:286.33 g/molALS-8176
CAS:ALS-8176 is a benzimidazole compound that has been shown to be effective against both wild-type and syncytial viruses. It is also active against the hepatitis B virus, which causes fulminant hepatitis in humans and death in 30% of cases. The antiviral activity of ALS-8176 was demonstrated by its ability to inhibit viral DNA synthesis and to prevent the release of new viral particles. ALS-8176 has also been shown to have a broad spectrum of activity against paramyxoviruses, including mumps, measles, and respiratory syncytial virus (RSV). This drug can be used for the treatment of influenza A and B when administered during the early stages of infection. ALS-8176 blocks the antibody response to influenza virus infection as well as monoclonal antibody binding sites on the hemagglutinin protein, preventing fusion between infected cells.Formula:C18H25ClFN3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:433.86 g/molPolyoxin B
CAS:Polyoxin B is a natural product that is produced by the fungus Polyporus umbellatus. It is a synthetase inhibitor that specifically inhibits the enzyme malic acid synthetase in bacteria and fungi. Polyoxin B has been shown to have antifungal activity in vitro and to inhibit the growth of Cryptococcus neoformans, which may be due to its ability to inhibit terminal residues, such as acetate extract, bacterial strain, and synthase enzyme.Formula:C17H25N5O13Purity:Min. 70%Color and Shape:Yellow PowderMolecular weight:507.41 g/molN6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
CAS:Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides containing 2’-O-(2-methoxyethyl) adenosine nucleoside units. Using a chemical approach rather than an enzymatic one allows custom-made oligonucleotides of a desired sequence to be obtained. 3’-Cyanoethyl phosphoramidites are typically modified by reaction with an appropriate alcohol in the presence of an azole catalyst such as imidazole or 1H-tetrazole. N6-Benzoyl-5'-O-DMT-2'-O-MOE-adenosine 3'-CE phosphoramidite has been used in the synthesis of 2’-modified oligonucleotides as protein binding modulators.Formula:C50H58N7O9PPurity:Min. 95%Color and Shape:PowderMolecular weight:932.01 g/molGuanosine 5'-diphosphate sodium
CAS:Pyruvate kinase substrate
Formula:C10H15N5O11P2•Na2Purity:Min. 95%Color and Shape:PowderMolecular weight:466.19 g/mol2'-O-Propargyladenosine
CAS:2'-O-Propargyladenosine is a modified nucleoside that belongs to the group of deoxyribonucleosides. It is an activator of viral DNA polymerases, which causes the synthesis of viral DNA to stop. This compound has antiviral and anticancer activities. 2'-O-Propargyladenosine has been shown to be effective against various human cancer cell lines in vitro and in vivo. It is a synthetic nucleoside with high purity, showing no detectable impurities by HPLC analysis.
Formula:C13H15N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:305.29 g/mol8-Iodoadenosine
CAS:8-Iodoadenosine is a macrocyclic inhibitor that binds to the phosphate group on ATP. This binding prevents ATP from being hydrolyzed to ADP and inorganic phosphate, which inhibits the formation of ATP. 8-Iodoadenosine has been shown to inhibit the proliferation of some cancer cells by interfering with their ability to synthesize proteins. It has also been shown to be an effective treatment for parasitic infections caused by Entamoeba histolytica. 8-Iodoadenosine has also been shown to inhibit protein synthesis in bacteria, fungi, and parasites.
Formula:C10H12IN5O4Purity:Min. 95%Molecular weight:393.14 g/mol2'-Deoxyadenosine
CAS:2'-Deoxyadenosine is a nucleoside that is found in DNA. It has been shown to have potent anticancer activity against carcinoma cell lines and to bind to the adenosine receptor A3. 2'-Deoxyadenosine has also been shown to inhibit the production of inflammatory cytokines, such as tumor necrosis factor-α and interleukin-6, from nuclear extracts of mouse tumor cells. This nucleoside may be a potential drug target for the treatment of cancer and inflammation.Formula:C10H13N5O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:251.24 g/mol[(2S,6R)-6-{N6-Benzoyladenin-9-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:Nucleotide analogue for use in oligonucleotide synthesis
Formula:C38H37ClN7O4PPurity:Min. 95%Color and Shape:PowderMolecular weight:722.17 g/molN2-Ethyl-2′-deoxyguanosine - 98 % HPLC
CAS:N2-Ethyl-2′-deoxyguanosine is an important metabolite of N2-ethyl-3′,5′-dideoxyadenosine (NEDA) and has been detected in urine samples from Sprague-Dawley rats. The biological properties of this metabolite are not well understood, but it has been shown to have genotoxic effects in mammalian cells and to be carcinogenic in a rat model. N2-Ethyl-2′-deoxyguanosine is also able to enhance the repair of damaged DNA and has functional groups that are similar to those found in cancer cells.
Formula:C12H17N5O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:295.29 g/mol
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