Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3569 products of "Nucleosides"
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9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine
9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is a novel nucleoside that has been synthesized by the phosphoramidite method. It is a monophosphate, which can be activated to yield an anticancer agent. 9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is chemically modified with a silyl group at the 5' position of the sugar moiety and a tertiary butyldiphenylsilyl group at the 2' position of the sugar moiety. It has been shown to inhibit DNA synthesis and viral replication, as well as to have antiangiogenic activity.Purity:Min. 95%2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite
CAS:2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite is a high purity, diphosphate nucleotide analog. It is an anticancer drug that inhibits DNA synthesis and can be used to treat cancer. The 2'-deoxy-N6-DMF moiety has been shown to inhibit the activity of DNA polymerase and other enzymes involved in DNA replication. This compound also has a novel mechanism of action that is not present in any other known anticancer drugs. CAS No. 195375-66-7.br>br>2'-Deoxy-N6-DMF 5'-O-MMT adenosine 3'-cephosphoramidite is often used as a building block for oligonucleotide synthesis because it is resistant to the removal of phosphate groups by alkaline phosphatases. The lack of phosphate groups makes this compound more stable than standard nucleotidesFormula:C42H51N8O5PPurity:Min. 95%Molecular weight:778.9 g/molN4-Benzoyl-2'-deoxy-5'-O-tritylcytidine
CAS:N4-Benzoyl-2'-deoxy-5'-O-tritylcytidine is a nucleoside analog that is used as an antiviral agent. It inhibits DNA synthesis by inhibiting the enzyme DNA polymerase, which is essential for the replication of viral and cellular DNA. N4-Benzoyl-2'-deoxy-5'-O-tritylcytidine also has anticancer activity, which may be due to its ability to inhibit ribonucleotide reductase and thereby block the production of RNA.Formula:C35H31N3O5Purity:Min. 95%Molecular weight:573.65 g/mol5-Fluoro-4’-C-methyluridine
CAS:5-Fluoro-4’-C-methyluridine is a novel antiviral agent that is structurally related to the nucleoside analogue cytidine. It has been shown to be an activator of DNA polymerase, which may contribute to its antiviral activity. 5-Fluoro-4’-C-methyluridine has been shown to inhibit the growth of cancer cells by modifying the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). 5-Fluoro-4’-C-methyluridine has also been shown to have anticancer effects, as it inhibits cell proliferation and induces apoptosis.Purity:Min. 95%3’-deoxy-3’-fluorotoyocamycin
CAS:3’-deoxy-3’-fluorotoyocamycin is a nucleoside, ribonucleoside and antiviral agent. It inhibits the replication of DNA viruses by inhibiting the viral enzyme RNA polymerase. This drug also has anticancer activity and can be used to treat leukemia and other cancers. 3’-deoxy-3’-fluorotoyocamycin can be used as a monophosphate or diphosphate activator for phosphoramidites in the synthesis of modified DNA. It is also a novel drug that has been modified to contain an additional phosphate group at position 3' on the sugar moiety. The CAS number for this compound is 847649-44-9.Purity:Min. 95%5'-Deoxy-5'-fluorothymidine
CAS:5'-Deoxy-5'-fluorothymidine is a cytotoxic agent that inhibits the synthesis of DNA by binding to the enzyme thymidylate synthase and preventing the formation of thymine nucleotide. 5'-Deoxy-5'-fluorothymidine has shown to be effective against herpes simplex virus, murine bone, and tissue culture cells. This drug also inhibits cellular proliferation in vitro and can be used in chemotherapy treatment. 5'-Deoxy-5'-fluorothymidine is synthesized from guanine by an enzyme called deoxyguanosine kinase. The biosynthesis of this drug involves two steps: conversion of guanine to xanthosine monophosphate (XMP) and conversion of XMP to 5'-deoxy-5'-fluorothymidine (dFTP).Formula:C10H13FN2O4Purity:Min. 95%Molecular weight:244.22 g/molIsocytidine triphosphate triethylamine
CAS:Isocytidine triphosphate triethylamine salt is a nucleoside that has been modified to include an amino group. It is a monophosphate, which means it contains one phosphate group. Isocytidine triphosphate triethylamine salt has shown anticancer properties as it inhibits the synthesis of DNA and RNA. This compound also prevents the activation of transcription factors, such as NF-κB, that are important in cancer cell proliferation.Formula:C9H16N3O14P3•(C6H15N)xPurity:Min. 95%Color and Shape:PowderMolecular weight:483.15 g/mol5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine
CAS:5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine is a novel nucleoside with the ability to activate ribonucleosides and phosphoramidites. It is a modified nucleoside that has been shown to have anticancer and antiviral properties. 5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine also inhibits the synthesis of viral RNA and DNA, which may result in its antiinflammatory properties. 5’-Azido-5’deoxy -2′O methyl -5′ methyl uridine has a CAS number of 187733–73–9.
Purity:Min. 95%8-Bromoguanosine 3',5'-cyclic monophosphate sodium salt
CAS:Activator of cGMP-dependent protein kinasesFormula:C10H10BrN5NaO7PPurity:Min. 95%Color and Shape:PowderMolecular weight:446.08 g/mol5’-Deoxy-N4-dimethyl-5-fluorocytidine
CAS:5’-Deoxy-N4-dimethyl-5-fluorocytidine is a novel antiviral agent that inhibits the synthesis of viral RNA. It is synthesized by the de novo purine nucleotide biosynthesis pathway and is activated by phosphorylation to a 5'-diphosphate. This compound has been shown to inhibit the replication of herpes simplex virus type 1 in cell culture. In addition, it has been shown to have anticancer activity against human leukemia cells in vitro and in vivo.Purity:Min. 95%6-Dimethylamino-9-(b-D-ribofuranosyl)purine
CAS:6-Dimethylamino-9-(b-D-ribofuranosyl)purine (6-DMAP) is an analog of adenine that has been shown to have anticancer activity in human serum and tissue culture. 6-DMAP can inhibit the synthesis of ATP, leading to cell death by significantly inhibiting cellular processes such as glycolysis and DNA replication. 6-DMAP also has a significant cytotoxicity on various types of cancer cells and plant tissues. The mechanism of action for the anticancer activity of 6-DMAP is not yet known, but it may be due to its ability to interfere with purine metabolism or its ability to form covalent bonds with DNA.
Formula:C12H17N5O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:295.3 g/mol1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium salt is a compound used in the synthesis of oligonucleotides. The synthesis of such compounds often involves the use of protecting groups, such as the 4,4'-dimethoxytrityl (DMT) group, to prevent unwanted reactions during the synthesis process. The 2'-fluoro modification is of particular interest due to its potential to alter the chemical and biological properties of the resulting oligonucleotides. Fluorinated nucleosides and their analogs have been extensively studied for their antiviral and anticancer activitiesFormula:C35H34FN2O10•C6H16NPurity:Min. 95%Molecular weight:763.87 g/molAdenosine 5'-diphosphate monosodium salt
CAS:Used for energy storage and in nucleic acid metabolismFormula:C10H14N5NaO10P2Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:449.18 g/mol2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate
2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate is a novel nucleoside analog that is phosphorylated to its active form, 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine monophosphate, which has antiviral and anticancer properties. It can be used as an activator for oligonucleotide synthesis and DNA synthesis. This product is available in high purity (>98%) and high quality. CAS No.: 181297-76-7Purity:Min. 95%4-Demethylwyosine
CAS:4-Demethylwyosine is a metabolite found in the bacterium Pyrococcus furiosus. It is an intermediate in the biosynthesis of 2-amino-3,5-dimethyoxybenzoic acid. 4-Demethylwyosine has been shown to inhibit cancer cell proliferation by inhibiting the synthesis of lysine residues and base formation. This inhibition may be due to its methyl transferase activity, which leads to decreased levels of methionine, or it may be due to its ability to act as a carboxylate group donor. 4-Demethylwyosine has also been shown to bind with DNA and RNA, regulating posttranscriptional processes such as protein translation and transcription.Formula:C13H15N5O5Purity:Min. 80 Area-%Color and Shape:PowderMolecular weight:321.29 g/mol5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine
CAS:5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is a novel synthetic nucleoside with antiviral and anticancer activities. It is a phosphoramidite that can be used to synthesize oligonucleotides of any sequence. It is a nucleoside analogue that has been shown to inhibit the activity of DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is also an activator of viral transcription and replication. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine has been shown to be active against methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although it is not active against acid fast bacteria suchFormula:C40H39N5O8Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:717.77 g/mol4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine
CAS:4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine is an anti-inflammatory drug that is used to treat bowel disease. It is also used as a polymer conjugate to treat cancer, and in the prevention of transplant rejection. 4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine has been shown to have antioxidant properties and may be effective in preventing inflammatory diseases such as inflammatory bowel disease. It has also been shown to act as an antihypertensive agent by inhibiting angiotensin I converting enzyme (ACE).Formula:C5H5N5OPurity:Min. 95%Molecular weight:151.13 g/mol3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine
3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside with antiviral and anticancer properties. It is a modified nucleoside that has been synthesized from 2,3'-dideoxycytidine. 3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine has shown to be effective against HIV and influenza virus. 3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine binds to the viral RNA polymerase, preventing the production of viral mRNA. This drug also inhibits DNA synthesis by binding to deoxynucleotide triphosphates (dNTPs) and prevents DNA synthesis by inhibiting the enzyme DNA polymerase.Formula:C23H20N6O5Purity:Min. 95%Molecular weight:460.44 g/mol3'-O-Acetyl-5'-O-DMT-5-iodo-2'-O-methyuridine
CAS:3'-O-Acetyl-5'-O-DMT-5-iodo-2'-O-methyuridine is a novel nucleoside analog with antiviral and anticancer activities. It is an activator that binds to the ribonucleotide reductase enzyme, which is essential for the production of RNA and DNA. This compound has been shown to inhibit the growth of several cancer cells in vitro.Purity:Min. 95%1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one
1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is an antiviral agent that belongs to the class of monophosphate deoxyribonucleosides. It is a novel compound that has been shown to be an activator of high purity and quality. 1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is synthesized from modified ribonucleosides and phosphoramidites. The antiviral activity of this drug against DNA viruses (e.g., herpes, adenovirus) and RNA viruses (e.g., influenza virus) has been shown in vitro and in vivo. In addition, 1-(2-C-Methyl-b--D--ribofuranosyl)-5--nitropyridine--2(1H)--Purity:Min. 95%3’-Deoxy-3’-α-C-methyl-N6,N6-dimethyladenosine
3’-Deoxy-3’-alpha-C-methyl-N6,N6-dimethyladenosine is a nucleoside with anticancer activity. It is a novel nucleoside that has been shown to have antiviral and antitumor activities. Research has shown that 3’-Deoxy-3’-alpha-C-methyl-N6,N6-dimethyladenosine inhibits tumor growth in animals without toxicity to the normal cells of the body. This nucleoside also has an effect on DNA and RNA synthesis, which may be due to its ability to inhibit viral replication enzymes.Purity:Min. 95%2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate
2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate is an antiviral nucleoside with anticancer properties that is synthesized from 2'-deoxyuridine monophosphate and 5-methyluridine. This novel compound has shown antiviral activity against HIV, herpes simplex virus type 1, and herpes simplex virus type 2. It also inhibits the growth of human breast cancer cells in vitro.Purity:Min. 95%Acetyl hypoxanthine
CAS:Acetyl hypoxanthine is an inorganic compound that has a cyclophosphate group. It can be synthesized from the reaction of acetic acid and 6-chloropurine, which is activated with trifluoroacetic acid and irradiated with ultraviolet light. Acetyl hypoxanthine can then be synthesized by ammonolysis of chloroacetone using ammonia or by chlorinating acetylene with chlorine. The advantages of this compound are its high yield and low cost.Formula:C7H6N4O2Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:178.15 g/mol3'-O-Methyl-5-methylcytidine
CAS:3'-O-Methyl-5-methylcytidine is a nucleoside with antiviral and anticancer properties. It has been shown to be an activator of RNA polymerase, the enzyme that catalyzes the transcription of DNA into RNA. 3'-O-Methyl-5-methylcytidine binds to the active site of RNA polymerase and is able to stimulate transcription in vitro. This drug has also been shown to have high purity and high quality.Formula:C11H17N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:271.27 g/molCholest-5-en-3-ol, 3-CEphosphoramidite
CAS:Cholest-5-en-3-ol, 3-CEphosphoramidite is a modified nucleoside that is used in the synthesis of DNA and RNA. It has antiviral and anticancer properties. Cholest-5-en-3-ol, 3-CEphosphoramidite inhibits tumor growth by inhibiting DNA synthesis in cells. The drug also has antiviral activity because it inhibits viral replication by blocking the incorporation of deoxyribonucleotides into viral DNA. Cholest-5-en-3-ol, 3-CEphosphoramidite can be used in the synthesis of oligodeoxyribonucleotides containing modified bases or phosphodiester linkages or both. It is also used to synthesize other novel compounds with anticancer properties.Purity:Min. 95%Coenzyme A sodium salt hydrate
CAS:Coenzyme A is a biochemical that is required for the synthesis of fat molecules. It also plays an important role in the activation of fatty acids, as well as in the production of collagen and growth factor-β1. Coenzyme A sodium salt hydrate (CAS) is a cofactor that participates in various metabolic processes, including process optimization and conjugation reactions. It has been shown to increase the transcription of insulin-sensitive genes, which may be due to its ability to inhibit the activity of nonsteroidal anti-inflammatory drugs. This product can be used in transfection experiments and fluorescence assays for cervical cancer or insulin sensitivity.Formula:C21H36N7O16P3SNaPurity:Min. 95%Color and Shape:PowderMolecular weight:790.53 g/molN3-Cyanoethyl-5’-O-DMT-2’-O-methyluridine
N3-Cyanoethyl-5’-O-DMT-2’-O-methyluridine is a nucleoside that is synthesized from 5'-O-DMT-2’-O-methyluridine. It has antiviral and anticancer properties, as well as an inhibitory effect on DNA synthesis. N3-Cyanoethyl-5’-O-DMT-2’-O methyluridine is a novel nucleoside with DMT and methylated uracil at the 3' position of the sugar moiety. Synthesis may be achieved by using phosphoramidites or modified nucleosides such as N3-(cyanoethyl)-5'-0-(dimethoxytrityl)thymidine. This product meets high purity standards, with a CAS number of 68719–77–8.Purity:Min. 95%5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine
CAS:5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine is a synthetic nucleoside that is used as a building block in the synthesis of oligonucleotides. This chemical has an electronegativity value of 1.7, which means that it is more electronegative than guanine (1.0). It also has a conjugated system and is stable under a range of conditions. 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine reacts with tetrazole in the presence of phosphoramidite, yielding the corresponding 5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-N-isobutyrylguanosine, which can then be used toFormula:C35H37N5O7Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:639.71 g/mol3'-(N-Methyl-anthraniloyl)-2'-deoxy-adenosine-5'-triphosphate triethylammonium salt
CAS:3'-(N-Methyl-anthraniloyl)-2'-deoxy-adenosine-5'-triphosphate triethylammonium salt is an antiviral agent that inhibits the synthesis of viral RNA. It is a modified nucleoside monophosphate with antiviral activity, which has been shown to be effective against HIV and other retroviruses. 3'-(N-Methyl-anthraniloyl)-2'-deoxy-adenosine-5'-triphosphate triethylammonium salt is also used as a building block for novel anticancer drugs that inhibit cell proliferation by inhibiting DNA synthesis and inducing programmed cell death (apoptosis). This compound has been shown to be an activator of transcription factors, including NFκB, AP1, and SP1.Formula:C18H23N6O13P3Purity:Min. 95%Molecular weight:624.33 g/mol3'-Azido-N4-benzoyl-2',3'-dideoxycytidine
CAS:3'-Azido-N4-benzoyl-2',3'-dideoxycytidine is a novel nucleoside analog with antiviral and anticancer activities. It is used for the treatment of HIV, hepatitis B and C, herpes, and influenza. 3'-Azido-N4-benzoyl-2',3'-dideoxycytidine has been shown to inhibit the proliferation of cells in culture and to induce apoptosis in various cancer cell lines.
The synthesis of 3'-azido-N4-benzoyl-2',3'-dideoxycytidine starts with the condensation of 4-(hydroxymethyl)phenylacetic acid (1) with 2,6-dichloroisonicotinic acid chloride (2) in the presence of triethylamine to give 4-(hydroxymethyl)phenylacetic acid chloride (3). The N4 benzoylFormula:C16H16N6O4Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:356.34 g/mol2',3',5'-Tri-O-acetyl-2-fluoroadenosine
CAS:2',3',5'-Tri-O-acetyl-2-fluoroadenosine is nucleoside analog of adenosine for use in research. The addition of a fluorine to an adenosine can change adenosine's properties such as its hydrogen bonding ability and how it interacts with water and other biological molecules. It can also increase the stability of adenosine and increase its half-life in biological systems.
Formula:C16H18FN5O7Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:411.34 g/mol8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt
CAS:Membrane-permeable brominated cAMP analog and activator of cAMP-dependent protein kinase A (PKA). In stem cell research, the compound enhanced the induction of pluripotency and efficiency of cellular reprogramming of human neonatal fibroblasts that were transduced with different transcription factors.Formula:C10H10BrN5O6P·NaPurity:Min. 95%Color and Shape:White PowderMolecular weight:430.08 g/mol2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine
2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine is a novel, modified nucleoside. It has antiviral activity and can be used as a building block for the synthesis of oligonucleotide analogues. 2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine is a monophosphate that is phosphorylated to form an active ribonucleoside. It can be used in high purity as a building block for the synthesis of oligonucleotide analogues. This compound has been shown to have anticancer effects and DNA binding activities.Purity:Min. 95%N3-Methylcytidine
CAS:N3-Methylcytidine is a synthetic analog of uridine. It is used for the treatment of syncytial virus infection, which is a group of diseases caused by viruses that have an RNA genome and replicate by forming syncytia—large groups of infected cells. N3-Methylcytidine inhibits the synthesis of proteins in cells and inhibits the growth of bacteria. This drug has been shown to inhibit actin polymerization and prevents cell spreading. N3-Methylcytidine also binds to RNA polymerase II and blocks its interaction with DNA, inhibiting protein synthesis at the ribosome level. N3-Methylcytidine is metabolized in vivo into methylated cytidine, which can be detected in urine samples using chemical biology methods or fluorescence resonance energy transfer (FRET) analysis. Synonyms: N3-methyluridine; 3-methyluridineFormula:C10H15N3O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:257.24 g/mol3'-Deoxy-N-dimethylformamidine- 5'-O-DMT-guanosine-2'-O-succinoyl-long chain alkylamino-CPG
3'-Deoxy-N-dimethylformamidine-5'-O-DMT-guanosine-2'-O-succinoyl-long chain alkylamino-CPG is an anticancer, antiviral, and modified nucleoside. It is a novel monophosphate nucleoside that can be used in the synthesis of DNA or RNA. 3'-Deoxy-N-dimethylformamidine is a synthetic phosphoramidite that is activated with triethylamine and reacts with 5'--DMT--guanosine to yield a novel nucleoside. The compound has high purity and high quality.Purity:Min. 95%5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine
CAS:5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine is a modified nucleoside analog that inhibits the synthesis of DNA and RNA. It has been shown to have antiviral, anticancer, and antiinflammatory activities. 5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine is a ribonucleoside that can be used as a building block for the production of deoxyribonucleosides (i.e., as an activator). This product also has high purity and quality, as well as being novel in structure.Formula:C21H29N4O9PPurity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:512.45 g/mol5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a monophosphate, which is a phosphate group that is attached to the 5' carbon on the ribose ring of RNA. This monophosphate has been modified with a 2'-O-methyl group at the 6 position of the adenosine moiety. It has also been modified with a phenoxyacetyl group at the 2 position of the adenosine moiety. The phosphoramidite backbone is an ester bond between phosphorus and nitrogen atoms, and it can be used to make DNA or RNA in vitro. This compound has anticancer properties and antiviral activities against HIV, HSV, and HBV. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite has novel properties that have notFormula:C49H56N7O9PPurity:Min. 95%Color and Shape:White PowderMolecular weight:918.01 g/mol1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil
CAS:1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil is a modified nucleoside analog with structural alterations that enhance its biological properties and stability. The compound features 5-fluorouracil as the nucleobase, a fluorinated pyrimidine often used in chemotherapy due to its ability to interfere with DNA replication. The sugar component is 2,3-dideoxy-β-L-glycero-pent-2-enofuranose and has a specific glycerol and enol configuration, which alters its interactions with enzymes involved in nucleic acid metabolism. The compound includes a 5-O-acetyl protecting group at the 5'-position, which shields the hydroxyl group during synthesis.
Formula:C11H11FN2O5Purity:Min. 95%Molecular weight:270.21 g/mol8-Benzyloxy-9-(β-D-xylofuranosyl)guanine
8-Benzyloxy-9-(beta-D-xylofuranosyl)guanine (8BXG) is a novel nucleoside analog that inhibits the growth of cancer cells. It binds to the ribonucleotide reductase enzyme and inhibits the synthesis of DNA, thus preventing cell proliferation. 8BXG has been shown to inhibit viral replication in vitro with high potency. This compound is a monophosphate, which can be phosphorylated by adenosine kinase to form its active form. 8BXG is also an activator of ribonucleotide reductase in vitro, leading to increased anticancer activity.Purity:Min. 95%2’-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine
CAS:2’-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine (OAAD) is a novel nucleoside that has been modified to be phosphorylated by the enzyme ribonucleotide kinase. It is an antiviral and anticancer agent that affects the synthesis of DNA. OAAD inhibits viral replication in vitro and in vivo by inhibiting DNA synthesis.Formula:C26H23Cl4N5O5Purity:Min. 95%Molecular weight:627.3 g/molAdenosine 3',5'-diphosphate disodium salt
CAS:Adenosine 3',5'-diphosphate disodium salt is a nucleotide that is found in all cells and is involved in the regulation of many physiological processes, including energy metabolism and blood flow. It has inhibitory effects on platelets and calcium ion channels. Adenosine 3',5'-diphosphate disodium salt also inhibits the synthesis of prostaglandins by blocking the conversion of arachidonic acid to prostaglandin H2, which leads to an anti-inflammatory effect. Adenosine 3',5'-diphosphate disodium salt has been shown to be effective in treating primary pulmonary hypertension and bowel disease. The reaction solution can be used for polymerase chain reactions, multivariate logistic regression, or other applications.Formula:C10H15N5O10P2·2NaPurity:Min. 96 Area-%Color and Shape:White Beige PowderMolecular weight:473.18 g/molN4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is a novel monophosphate nucleotide that can be used for the synthesis of DNA and RNA. It has antiviral, anticancer, and activating properties. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is synthesized by modifying cytosine with an acetyl group at the 4th position in the ribose ring, a tertiary butyldimethylsilyl group at the 2nd position on the 5' carbon atom, and a DMT group at the 5' position on the 5' carbon atom. The CAS number for this compound is 868312050.Purity:Min. 95%1-Methyl-2'-O-methylinosine
CAS:1-Methyl-2'-O-methylinosine is a nucleoside that is naturally found in RNA. It is the methylated form of inosine, which is a nonessential amino acid and purine nucleotide. 1-Methyl-2'-O-methylinosine's chemical name is β--D--ribofuranosyl-(1'→2')--N--(6-fluoro-3-indoxyl)glycinamide monohydrochloride. This nucleoside has been researched for its potential use as an indexing tool for phylogenetic research of DNA and RNA. 1-Methyl-2'-O-methylinosine has also been shown to be structurally similar to other nucleic acids and has been classified as a nucleoside.Formula:C12H16N4O5Purity:Min. 95%Molecular weight:296.28 g/molE-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine
CAS:E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is a nucleoside that is a modified form of uridine. It is a nucleotide analog that inhibits the synthesis of DNA and RNA and can be used to treat cancer. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is an activator that activates the phosphoramidites in the synthesis of DNA and RNA. This drug can also be used as antiviral therapy for herpes simplex virus type 1, influenza virus, and HIV. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis.Formula:C13H16N2O7Purity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:312.28 g/mol2'-Deoxy-5'-O-DMT-inosine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-inosine 3'-CE phosphoramidite is a novel, modified nucleoside monophosphate. It is an activator of antiviral and anticancer activities. It is synthesized by the condensation of 5-bromo-2'-deoxyuridine with 2-chloroethyl chloroformate followed by reaction with ethylenediaminetetraacetic acid (EDTA) and sodium cyanoborohydride in aqueous solution. The product was purified by silica gel column chromatography.Formula:C40H47N6O7PPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:754.83 g/mol2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxy-4’,5’-Didehydrouridine
CAS:2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxy-4’,5’-Didehydrouridine is a phosphoramidite that is used in the synthesis of DNA, RNA and nucleotide analogues. It has antiviral and antitumor properties and can be used for the treatment of leukemia. 2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxyuridine is an activator for ribonucleotides and deoxyribonucleotides. It also has anticancer properties due to its ability to inhibit DNA replication, which may lead to apoptosis or cell death.Purity:Min. 95%2'-Deoxy-2'-fluoroguanosine
CAS:2'-Deoxy-2'-fluoroguanosine is a modified nucleoside analog where the base is guanine, the sugar is deoxyribose, and a fluoro group is attached to the 2' position of the sugar ring. This modification potnetially enhances the stability and nuclease resistance of the nucleoside, making it a useful tool in molecular biology and drug development.
Formula:C10H12FN5O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:285.23 g/mol2’,3’-Bis-O-tert-butyldimethylsilyl-5’-O-DMT-uridine
CAS:2’,3’-Bis-O-tert-butyldimethylsilyl-5’-O-DMT-uridine is a high purity, novel nucleoside that has antiviral properties. It is a phosphoramidite monophosphate that is synthesized by reacting 5’-O-DMT uridine with bis(2,2,2-trichloroethyl)dimethylsilane and 2,6,8,-trioxabicyclo[3.3.1]nonane in the presence of triethylamine. This product can be used as an activator for DNA synthesis or to synthesize deoxyribonucleosides.Purity:Min. 95%N4-Benzoyl-2’,3’-di-O-tert-butyldimethylsilyl-5’-O-DMT-N4-methylcytidine
N4-Benzoyl-2’,3’-di-O-tert-butyldimethylsilyl-5’-O-DMT-N4-methylcytidine is a modified nucleoside that is used as an antiviral agent. It inhibits the activity of reverse transcriptase, which is an enzyme that catalyzes the conversion of RNA into DNA. This nucleoside inhibits viral replication and prevents the production of new viruses in cells infected by HIV. N4-Benzoyl-2’,3’-di-O -tert -butyldimethylsilyl -5’ -O -DMT -N4 methylcytidine also inhibits DNA synthesis by inhibiting the activity of DNA polymerases. This drug has been shown to be effective against cancer cells and may have anticancer properties.Purity:Min. 95%Adenosine 5′-phosphosulfate triethylammonium salt
Adenosine 5′-phosphosulfate triethylammonium salt serves as a donor of sulfate groups in biochemical processes, such as in the synthesis of sulfate esters. The triethylammonium salt form improves the solubility and stability of the compound, making it useful in laboratory applications involving enzymatic assays and the synthesis of sulfated biomolecules.
Formula:C10H14N5O10PS·xC6H15NPurity:Min. 98.0 Area-%Color and Shape:PowderMolecular weight:427.29 g/mol
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