Serotonin–Norepinephrine Reuptake Inhibitors (SNRI)
Serotonin–Norepinephrine Reuptake Inhibitors (SNRI) are a class of compounds that inhibit the reuptake of the neurotransmitters serotonin and norepinephrine, thereby increasing their levels in the synaptic cleft. This action enhances neurotransmission and is commonly used in the treatment of depression, anxiety, and chronic pain. SNRIs are vital tools in studying mood disorders and the development of antidepressant therapies. At CymitQuimica, we provide a selection of SNRIs to aid your research in psychopharmacology, mood disorders, and neurobiology.
Found 427 products of "Serotonin–Norepinephrine Reuptake Inhibitors (SNRI)"
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N,N-Didesmethyl Sibutramine HCl
CAS:Formula:C15H22ClN·HClColor and Shape:White To Off-White SolidMolecular weight:251.80 36.46Atomoxetine EP Impurity G DiHCl (Mixture of Diastereomers)
CAS:Formula:C27H34N2O2·2HClColor and Shape:White To Off-White SolidMolecular weight:418.58 2*36.46Desvenlafaxine Succinate (O-Desmethyl Venlafaxine Succinate)
CAS:Formula:C16H25NO2·C4H6O4Color and Shape:White To Off-White SolidMolecular weight:263.38 118.09N-Desethyl L-Milnacipran HCl
Formula:C13H18N2O·HClColor and Shape:Off-White SolidMolecular weight:218.30 36.465-Hydroxy-6-Methoxy Duloxetine Sulfate-d3 Triethylamine Salt
Formula:C19H18D3NO6S2·Et3NMolecular weight:426.52 101.19Duloxetine
CAS:<p>Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.</p>Formula:C18H19NOSPurity:99.71% - 99.89%Color and Shape:SolidMolecular weight:297.41N,O-Didesmethyl Venlafaxine-13C-d3 ( (Mixture of Diastereomers)
Formula:C1413CH20D3NO2Molecular weight:253.36Venlafaxine EP Impurity D-13C-d3 HCl (Venlafaxine USP Related Compound A-13C-d3, N-Desmethyl Venlafaxine-13C-d3 HCl)
CAS:Formula:C1513CH22D3NO2·HClMolecular weight:267.39 36.46Venlafaxine Related Compound 4 (S-4-(1-(1-Hydroxycyclohexyl)-2-((4-hydroxyphenylethyl) amino) ethyl) phenol)
Formula:C22H29NO3Molecular weight:355.48rac-Duloxetine Oxalate
CAS:Formula:C18H19NOS·C2H2O4Color and Shape:Off-White SolidMolecular weight:297.42 90.03Milnacipran Impurity 31
CAS:Formula:C11H10O2Color and Shape:White To Off-White SolidMolecular weight:174.20Venlafaxine
CAS:<p>Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD),</p>Formula:C17H27NO2Purity:99.2%Color and Shape:White Solid CrystallineMolecular weight:277.4N-Nitroso Atomoxetine EP Impurity B (N-Nitroso (S)-Atomoxetine)
Formula:C17H20N2O2Molecular weight:284.36Milnacipran
CAS:<p>Milnacipran, an SNRI with 85% bioavailability, treats fibromyalgia and is well absorbed orally.</p>Formula:C15H22N2OColor and Shape:SolidMolecular weight:246.35Desmethyl Atomoxetine Hydrochloride
CAS:Controlled ProductFormula:C16H20ClNOColor and Shape:Off-WhiteMolecular weight:277.79(-)-N,N-Bisdesmethyl Tramadol
CAS:Controlled Product<p>Applications A optically active metabolite of Tramadol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formula:C14H21NO2Color and Shape:NeatMolecular weight:235.32(E)-N-Methylcinnamylamine Hydrochloride
CAS:Controlled Product<p>Applications (E)-N-Methylcinnamylamine is an 3-amino-1-phenyl-prop-1-ene derivative with potential to inhibit and inactivate monoamine oxidase.<br>References Williams, C.H. et al.: Biochim. Biophys. Acta Prot. Struc. Mol. Enzymol., 119, 111 (1992);<br></p>Formula:C10H14ClNColor and Shape:NeatMolecular weight:183.68N-Nitroso Rac N-Desmethyl Tramadol
Formula:C15H22N2O3Color and Shape:Colourless To Light YellowMolecular weight:278.347rac,trans-Milnacipran Hydrochloride
CAS:Controlled Product<p>Applications rac,trans-Milnacipran Hydrochloride is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moret, C., et al.: Neuropharmacology, 24, 1211 (1985), Palmier, C., et al.: Eur. J. Clin. Pharmacol., 37, 235 (1989), Spencer, C.M., et al.: Drugs, 56, 405 (1998)<br></p>Formula:C15H23ClN2OColor and Shape:NeatMolecular weight:282.81(±)-Sibutramine
CAS:Controlled Product<p>Applications (±)-Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.<br>References Hanotin, C., et al.: Int. J. Obesity, 22, 32 (1998)<br></p>Formula:C17H26ClNColor and Shape:Off White SolidMolecular weight:279.851-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride(rac N-Desmethyl Venlafaxine Hydrochloride)
CAS:<p>Impurity Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A<br>Applications 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride (Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A) is a metabolite of Venlafaxine (V120000), which is a selective serotonin noradrenaline reuptake inhibitor, used as an antidepressant.<br>References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000);<br></p>Formula:C16H25NO2·ClHColor and Shape:WhiteMolecular weight:299.84(-)-O-Desmethyl Tramadol
CAS:Controlled Product<p>Applications A optically active metabolite of Tramadol.<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formula:C15H23NO2Color and Shape:White To Off-WhiteMolecular weight:249.35ent Atomoxetine-d3, Hydrochloride
CAS:Controlled ProductFormula:C17H19D3ClNOColor and Shape:NeatMolecular weight:294.83N-Nitroso Duloxetine
CAS:Formula:C18H18N2O2SColor and Shape:Colourless To Light YellowMolecular weight:326.4135-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane Hydrochloride
CAS:Controlled Product<p>Impurity Venlafaxine EP Impurity E<br>Applications 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane Hydrochloride (Venlafaxine EP Impurity E) is a useful building block in the synthesis of various pharmaceuticals.<br></p>Formula:C17H25NO2·ClHColor and Shape:Beige To Light YellowMolecular weight:311.85D,L-Venlafaxine-d11 Hydrochloride (Major)
CAS:Controlled Product<p>Applications D,L-Venlafaxine-d10 Hydrochloride is the labeled analogue of D,L-Venlafaxine Hydrochloride (V120000), a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant.<br>References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992); Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000)<br></p>Formula:C17H17D11ClNO2Color and Shape:Off White SolidMolecular weight:324.93rac N-Methyl Atomoxetine Oxalate
CAS:<p>Applications rac N-Methyl Atomoxetine Oxalate is a derivative of Atomoxetine which acts as a norepinephrine reuptake inhibitor.<br>References Farid, N.A., et al.: J. Clin. Pharmacol., 25, 296 (1985), Gehlert, D.R., et al.: J. Neurochem., 64, 2792 (1995), Hwamg. et al.: Neurosci. Lett., 265, 151 (1999), Ring, B.J., et al.: Drug Metab. Dispos., 30, 319 (2002),<br></p>Formula:C18H23NO·C2H2O4Color and Shape:Off White SolidMolecular weight:359.42D,L-Venlafaxine
CAS:Controlled Product<p>Applications A selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant.<br>References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000)<br></p>Formula:C17H27NO2Color and Shape:White To Off-WhiteMolecular weight:277.40(±)-Venlafaxine-d6 Hydrochloride (N,N-dimethyl-d6)
CAS:Controlled Product<p>Applications (±)-Venlafaxine-d6 HCl (N,N-dimethyl-d6) (CAS# 1062606-12-5) is a useful isotopically labeled research compound.<br></p>Formula:C172H6H21NO2·ClHColor and Shape:NeatMolecular weight:319.90(-)-Tramadol Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An analgesic. Used in the treatment of urinary incontinence.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Raffa, R.B., et al.: J. Pharmacol. Exp. Ther., 267, 331 (1993)<br></p>Formula:C16H25NO2·ClHColor and Shape:NeatMolecular weight:299.84D,L-Venlafaxine-d6
CAS:Controlled ProductFormula:C17H21D6NO2Color and Shape:Off-WhiteMolecular weight:283.44N-Nitroso-Atomoxetine
Controlled ProductFormula:C17H20N2O2Color and Shape:Off WhiteMolecular weight:284.353(R)-3-Chloro-1-phenyl-1-(2-methylphenoxy)propane
CAS:Controlled ProductFormula:C16H17ClOColor and Shape:NeatMolecular weight:260.76Sibutramine, Hydrochloride Monohydrate
CAS:Controlled ProductFormula:C17H26ClN·ClH·H2OColor and Shape:Off White SolidMolecular weight:334.32Hordenine
CAS:<p>Applications A phenethylamine alkaloid with antibacterial and antibiotic properties found mainly in plants from the cactaceae family. It showed effects similar to Cytosine (C998950) and acted as a depressant on the central nervous system (CNS) during animal testing.<br>References Aliev, K.U. et al.: Med. Zhur. Uzbek., 8, 71 (1966); Ghosal, S. et al. Planta Medica, 22, 434 (1972); Starha, R. et al.: Biochem. Sys. Ecol., 27, 839 (1999);<br></p>Formula:C10H15NOColor and Shape:Light Yellow SolidMolecular weight:165.23Ethyl α-(p-Methoxyphenyl)-β-(dimethylamino)propionate
CAS:<p>Impurity Venlafaxine EP Impurity B<br>Applications Ethyl α-(p-Methoxyphenyl)-β-(dimethylamino)propionate (Venlafaxine EP Impurity B) is an impurity of Venlafaxine (impurity B).<br></p>Formula:C14H21NO3Color and Shape:NeatMolecular weight:251.32Dehydro Venlafaxine
CAS:Controlled ProductFormula:C17H25NOColor and Shape:NeatMolecular weight:259.39Desmethyl Sibutramine
CAS:Controlled Product<p>Applications Desmethyl Sibutramine is a metabolite of Sibutramine (S422500), a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.<br>References Hanotin, C., et al.: Int. J. Obesity, 22, 32 (1998); Woolard, J., et al.: J. Pharmacol. Exp. Ther., 308, 1102 (2004); Geranton, S., et al.: Neuropharmacol., 46, 511 (2004)<br></p>Formula:C16H24ClNColor and Shape:Colourless To YellowMolecular weight:265.822-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene
CAS:<p>2-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene is a synthetic compound that has been used as an impurity standard for the drug product and API. It has also been used for the pharmacopoeia, research and development, and analytical purposes. This compound is a metabolite of erythromycin.</p>Formula:C18H19NOSPurity:Min. 95%Color and Shape:White To Pink Or Yellow SolidMolecular weight:297.42 g/molEthyl 3-(dimethylamino)-2-(4-methoxyphenyl)propanoate
CAS:<p>Ethyl 3-(dimethylamino)-2-(4-methoxyphenyl)propanoate is an impurity standard for drug product. It is a high purity, API impurity, HPLC standard and niche chemical that is found in the CAS No. 323176-93-8. This compound is used in drug development and analytical research. It is a synthetic compound that can be custom synthesized, natural or found in research and development.</p>Formula:C14H21NO3Purity:(%) Min. 95%Color and Shape:Clear Viscous LiquidMolecular weight:251.32 g/mol(S)-Duloxetine succinamide
CAS:<p>Duloxetine succinamide is a chromatographic, solid, acidic compound. It has been synthesized by reacting (S)-duloxetine hydrochloride with succinic anhydride in the presence of triethylamine and acetonitrile. The reaction mixture was purified by high-performance liquid chromatography to produce the desired product. The purity of the compound was confirmed by postulating that it should have a reversed-phase HPLC profile similar to that of duloxetine succinate. Duloxetine succinamide is not soluble in water and is insoluble in organic solvents such as acetone, chloroform, ether, or benzene. The compound is stable at room temperature but decomposes when heated at higher temperatures.<br>!--</p>Formula:C22H23NO4SPurity:Min. 95%Color and Shape:PowderMolecular weight:397.49 g/mol4-Methoxy-N,N-dimethyl-phenethylamine
CAS:Controlled Product<p>4-Methoxy-N,N-dimethylphenethylamine is a natural product that has been shown to inhibit the transfer of bacteria from the environment to food. It also has regulatory properties and can be used as a supplement in dietary drinks. 4-Methoxy-N,N-dimethylphenethylamine is an alkaloidal extract and has been shown to have antibacterial activity against Escherichia coli, Salmonella enterica, and Listeria monocytogenes. This compound was also found to have diffraction properties, which are related to its ability to bind DNA in bacterial cells.</p>Formula:C11H17NOPurity:Min. 95%Color and Shape:Clear LiquidMolecular weight:179.26 g/molN-Methyl-3-(1-naphthalenyloxy)-3-(3-thienyl) propanamine tartrate
<p>N-Methyl-3-(1-naphthalenyloxy)-3-(3-thienyl) propanamine tartrate is an impurity standard used for the quantitative analysis of norephedrine in pharmaceutical products. It is also a metabolite of methamphetamine, which has been shown to have anti-inflammatory activities.</p>Formula:C18H19NOS·C4H6O6Purity:Min. 95%Molecular weight:447.5 g/mol3-(Dimethylamino)-1-(3-thienyl)propan-1-ol
CAS:<p>3-(Dimethylamino)-1-(3-thienyl)propan-1-ol (DMAT) is an impurity that was identified in a drug product and that is not found in the natural form. DMAT is an intermediate of the synthesis of DMH, which is used as a research and development tool. DMAT has been shown to be metabolized by cytochrome P450 enzymes and other oxidative reactions, such as oxidation by cytochrome P450 enzymes or conjugation with glucuronic acid. DMAT also binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>Formula:C9H15NOSPurity:Min. 95%Color and Shape:White to yellow solid.Molecular weight:185.29 g/molN,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate
CAS:<p>N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate (DMNPA) is a synthetic compound with the molecular formula C14H17NO. DMNPA is used as an analytical reference standard for the quantification of N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2thienyl) propanamine HCl by HPLC. DMNPA has been shown to be a metabolite of the drug product, where it is formed from oxidation of the parent drug.</p>Formula:C19H21NOS·C4H6O6Purity:Min. 95%Molecular weight:461.53 g/molN-Methyl-3-(4-naphthol)-3-(2-thienyl) propanamine hydrochloride
CAS:<p>N-Methyl-3-(4-naphthol)-3-(2-thienyl) propanamine hydrochloride is a custom synthesis that has been shown to be a metabolite of naphthalene. It has been used as an impurity standard for N-methyl-3-(4-naphthol)-2-[(5-nitrofuran-2-yl)methyl] propanamine and in metabolism studies.</p>Formula:C18H19NOS•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:333.88 g/molD,L-O-Desmethyl Venlafaxine-d10
CAS:Controlled Product<p>Applications D,L-O-Desmethyl Venlafaxine-d10, is the labeled analogue of D,L-O-Desmethyl Venlafaxine (D296500), a metabolite of Venlafaxine (V120000).<br>References Shams, M., et al.: J. Clinic. Pharm. Ther., 31, 493 (2006), Huq, F., et al.: J. Pharmacol. Toxicol., 3, 27 (2008), Isoherranen, N., et al.: Chem. Res. Toxicol., 22, 294 (2009),<br></p>Formula:C162H10H15NO2Color and Shape:White SolidMolecular weight:273.44
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