Complement System
The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.
Found 178 products for "Complement System".
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SB290157 trifluoroacetate
CAS:SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).Formula:C24H29F3N4O6Purity:98.93% - 99.89%Color and Shape:White SolidMolecular weight:526.51PMX 205 acetate(514814-49-4 free base)
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).Formula:C47H66N10O8Purity:99.4%Color and Shape:SolidMolecular weight:899.09Ref: TM-T12506L1
1mg105.00€5mg266.00€10mg350.00€1mL*10mM (DMSO)374.00€25mg745.00€50mg1,189.00€100mg1,735.00€Vesencumab
CAS:Vesencumab (MNRP-1685A) is an IG1 antibody targeting NRP-1 with anti-angiogenic and anti-tumor activity. Vesencumab can be used to study solid tumors.Purity:99.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 99.2% (SDS-PAGE); 96.6% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.22 kDaDexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Formula:C22H29FO5Purity:98% - 99.91%Color and Shape:Crystals From Ether (Ntp 1992)Molecular weight:392.46Tesidolumab
CAS:Tesidolumab, a fully human IgG1/λ anti-C5 monoclonal antibody, inhibits crovalimab and C5, preventing membrane attack complex formation.Purity:99.72% (SEC-HPLC) - > 95%Color and Shape:LiquidMolecular weight:144.16 kDaCyclosporin A
CAS:Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.Formula:C62H111N11O12Purity:99.00% - 99.92%Color and Shape:White SolidMolecular weight:1202.61Ravulizumab
CAS:Ravulizumab (ALXN1210) is a humanized antibody for blocking complement activation, treating PNH, aHUS, and myasthenia gravis.Purity:> 95%Color and Shape:LiquidMolecular weight:145.80 kDaVilobelimab
CAS:Vilobelimab (CaCP-29, IFX-1), a monoclonal antibody, inhibits C5a to reduce inflammation and is researched in sepsis and COVID-19 studies.Purity:99% (SDS-PAGE); 98.9% (SEC-HPLC) - 99% (SDS-PAGE); 98.9% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.86 kDaAvdoralimab
CAS:Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting complement C5a receptor 1 (C5aR1).Purity:>95%Color and Shape:LiquidMolecular weight:145.9 kDaLampalizumab
CAS:Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Factor D, which can be used in cardiovascular disease research.Purity:>95%Color and Shape:LiquidMolecular weight:143.8 kDaSutimlimab
CAS:Sutimlimab: monoclonal antibody, inhibits complement protein C1, treats cold agglutinin-induced hemolysis.Purity:> 95%Color and Shape:Transparent LiquidMolecular weight:144.8 kDaPIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Formula:C71H123N19O21S2·xC2HF3O2Color and Shape:SolidFactor B-IN-5
CAS:Factor B-IN-5 is a complement factor B inhibitor, which can be used to study immune-related diseases.Formula:C27H32N2O4Purity:98.19%Color and Shape:SoildMolecular weight:448.55Vensobafusp alfa
CAS:Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.Color and Shape:LiquidPIC1 PA
CAS:PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding purified C1q.Formula:C71H123N19O21S2Color and Shape:SolidMolecular weight:1642.98BM213
CAS:BM213 is a useful organic compound for research related to life sciences and the catalog number is T35399.Formula:C43H70N12O10Purity:98%Color and Shape:SoildMolecular weight:915.09Zilucoplan TFA
Zilucoplan TFA (RA101495), a 15-amino acid macrocyclic peptide, serves as a potent inhibitor of complement component 5 (C5).Formula:(C2H4O)nC126H186N24O32·C2HF3O2Purity:98%Color and Shape:SolidMolecular weight:3562.18 (free base)C1s-IN-1 trihydrochloride
CAS:C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Formula:C16H22Cl3N5Color and Shape:SolidMolecular weight:390.74Complement C1s-IN-1
CAS:Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexesFormula:C22H20F2N6OPurity:97.77%Color and Shape:Yellow SolidMolecular weight:422.43C5a Anaphylatoxin (human)
CAS:C5a Anaphylatoxin (human) is a pro-inflammatory peptide that functions as a leukocyte chemoattractant, utilized in researching inflammation and immune responsesFormula:C350H578N108O107S8Purity:98%Color and Shape:SolidMolecular weight:8267.51Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Formula:C128H190N24O33Color and Shape:SolidMolecular weight:2593.02POT-4 acetate
POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.Formula:C74H106N22O20S2Purity:98%Color and Shape:SolidMolecular weight:1687.9Factor B-IN-1
CAS:Factor B-IN-1 is a Factor B inhibitor.Formula:C19H16N4O2Color and Shape:SolidMolecular weight:332.3559Anti-GC1q R/C1QBP Antibody (60.11)
Anti-GC1q R/C1QBP Antibody (60.11) is a mouse IgG1, κ chimeric antibody designed to target human GC1q R/C1QBP. The recommended isotype control for this antibody is Mouse IgG1 kappa, Isotype Control.Color and Shape:Odour LiquidPOT-4 TFA
POT-4 TFA, a Compstatin derivative, inhibits C3 activation, for macular degeneration research.Formula:C74H103F3N22O20S2Color and Shape:SolidMolecular weight:1741.87ARC186
ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.Color and Shape:SolidMolecular weight:120702.76TLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Formula:C107H170N40O26Purity:98%Color and Shape:SolidMolecular weight:2432.75Pozelimab
CAS:Pozelimab (REGN 3918) is a humanized antibody targeting component 5 (C5), used for research on Pozelimab disease.Purity:98.94% (SEC-HPLC) - 98.94% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:144.78 kDaPMX 205
CAS:PMX 205 is an effective complement antagonist of the C5a receptor.Formula:C45H62N10O6Purity:98%Color and Shape:SolidMolecular weight:839.04L-156,602
CAS:L-156,602 has a wide range of applications in life science related research.Formula:C38H64N8O13Color and Shape:SolidMolecular weight:840.973C5a Receptor agonist, mouse, human
CAS:C5a Receptor Agonist (mouse, human) is a bioactive peptide derived from the C-terminus of the complement fragment 5 anaphylatoxin (C5a), functioning as anFormula:C44H72N10O7Purity:98%Color and Shape:SolidMolecular weight:853.11Claseprubart
CAS:Claseprubart is a monoclonal antibody that targets human complement C1s. It specifically binds to complement C1s, inhibiting the activation of the complement system and exerting immunosuppressive effects. Claseprubart shows potential for research in autoimmune diseases and inflammation-related conditions.Color and Shape:LiquidATWLPPR Peptide TFA
ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.Formula:C42H62F3N11O11Purity:98%Color and Shape:SolidMolecular weight:954Campneoside II
CAS:Campneoside II, a compound extracted from the wood of Paulownia tomentosa var. tomentosa, demonstrates remarkable anti-complement activity [1].Formula:C29H36O16Color and Shape:SolidMolecular weight:640.59PMX 205 Trifluoroacetate
PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.Formula:C47H63F3N10O8Color and Shape:SolidMolecular weight:953.06Olendalizumab
CAS:Olendalizumab is an anti-C5a mAb that inhibits neutrophil activation and cytokine storms by blocking the C5a/C5aR axis for sepsis and viral infection research.Color and Shape:LiquidPMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Formula:C47H65N11O7Purity:98%Color and Shape:SolidMolecular weight:896.09JPE-1375
CAS:JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Formula:C49H63FN10O9Color and Shape:SolidMolecular weight:955.08Vemircopan
CAS:Vemircopan is a complement factor D inhibitor.Formula:C29H28BrN7O3Color and Shape:SolidMolecular weight:602.493Certepetide
CAS:Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.Formula:C37H60N14O14S2Color and Shape:SolidMolecular weight:989.09Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Formula:C68H100F3N23O19S2Color and Shape:SolidMolecular weight:1664.79Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.Color and Shape:Odour SolidAMY-101
CAS:AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.Formula:C83H117N23O18S2Purity:98%Color and Shape:SolidMolecular weight:1789.11BCX 1470 hydrochloride
BCX 1470 hydrochloride is a serine protease inhibitor with anti-inflammatory activity that inhibits factor D hemolytic activity and may be used to study edema.Formula:C14H11ClN2O2S2Purity:99.71%Color and Shape:SolidMolecular weight:338.83Anti-CD88/C5AR1 Antibody (G2_anti-C5aR)
Anti-CD88/C5AR1 Antibody (G2_anti-C5aR) is a human monoclonal antibody (mAb) targeting C5AR1.Color and Shape:Odour LiquidC3a (70-77) (TFA)
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.Formula:C37H62F3N13O12Purity:99.92%Color and Shape:White SolidMolecular weight:937.96ASP-1948
ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.Color and Shape:Odour LiquidtLyP-1 peptide
CAS:tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.Formula:C31H59N15O10SColor and Shape:SolidMolecular weight:833.96CK3 peptide
CAS:CK3 peptide is an NRP-1-targeting peptide with the amino acid sequence CLKADKAKC. It specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging demonstrate that CK3 peptide significantly accumulates in xenograft tumors in nude mice. CK3 peptide is applicable for molecular imaging studies of breast cancer.Formula:C40H72N12O12S2Color and Shape:SolidMolecular weight:977.203Greziprubart
Greziprubart is a humanized IgG1κ monoclonal antibody that targets C5a, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour Liquid
