Aminoacids and derivatives

<p>Applications 2-(Acetylamino)-3-(phenylthio)propanoic acid is a useful chemical in research.<br></p>

<p>Applications Indole-3-pyruvic Acid is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmental changes.<br>References Kong, W., et al.: Plant Cell Physiol, 56, 715-726 (2015)<br></p>

<p>Applications N-Hydroxyphthalimide is used in the synthesis of a new class of antibacterials potent against macrolide resistant bacteria. Also used in the synthesis of pyrazolidines, isoxazolidines and tetrahydrooxazines.<br>References Agouridas, C. et al.: J. Med. Chem., 41, 4080 (1998); La Londe, R. et al.: Angew. Chem. Int. Ed., 49, 598 (2010);<br></p>

<p>Stability Hygroscopic<br>Applications 3,4-Dihydroxybenzaldehyde (cas# 139-85-5) is a compound useful in organic synthesis.<br></p>

<p>Applications Amino acid substitute tumor growth.<br>References Villiers, C.L., et al.: Eur. J. Biochem., 140, 421 (1984);<br></p>

<p>Applications Lacosamide is a mediication developed as and adjunctive treatment of partial-onset seizures and diabetic neuropthic pain.Lacosamide is a potent anticonvulsant.<br>References Choi, D., et al.: J. Med. Chem., 39, 1907 (1996), Morieux, P., et al.: Bioorg. Med. Chem., 16, 8968 (2008),<br></p>

<p>Applications Labelled N2-Lauroyl-L-glutamine (L178650). N2-Lauroyl-L-glutamine is used as a solubilizing detergent in a novel protein refolding system. N2-Lauroyl-L-glutamine can be synthesized enzymatically in glycerol-water system useing acylase I from pig kidney.<br>References Kudou, M. et al.: Protein Express. Purif., 75, 46 (2011); Wada, E. et al.: J. Am. Oil Chem. Soc., 79, 41 (2002);<br></p>

<p>Stability Decomposes under acidic condition, Hygroscopic<br>Applications 1,1’-Ethylidenebis[L-tryptophan] is a L-tryptophan (T947210) contaminant found in the peripheral blood mononuclear cells from patients with functional somatic syndromes.<br>References Barth, H., et al.: Clin. Experiment. Inmmunol., 126, 187 (2001); Simat, T.J., et al.: Adv. Experi. Med. Biol., 467, 469 (1999);<br></p>

<p>Stability Hygroscopic<br>Applications Spermidine is a biogenic polyamine formed from putrescine. Spermidine is a precursor of Spermine. Spermidine is essential for both normal and neoplastic tissue growth.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Abraham, A.K., et al.: Eur. J. Biochem., 106, 257 (1980), Mach, M., et al.: Biochem. J., 202, 153 (1982), Thyss, A., et al.: Eur. J. Cancer Clin. Oncol., 18, 611 (1982),<br></p>

<p>Applications L-Glutamine-2,3,3,4,4-d5 is the isotope labelled analog of L-Glutamine (G597000); an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.<br>References Rivett, A., et al.: J. Biol. Chem., 260, 300 (1985); Watford, M., et al.: Metabolism, 49, 141 (2000); Wilmore, D., et al.: J. Nutr., 131, 2543S (2001)<br></p>

<p>Stability Hygroscopic<br>Applications L-Glutamic Acid, Magnesium Salt Hydrobromide is an metabolite of L-Glutamic acid, a non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. It is also a key molecule in cellular metabolism. L-Glutamic Acid, Magnesium Salt Hydrobromide has also been investigated for sedative properties as a tranquilizer.<br>References McEntee, W., et al.: Psychopharmacology, 111, 391 (1993), Manev, H., et al.: Mol. Pharmacol., 36, 106 (1989), Hamanaka, T., et al.: Toho. Igakkai. Zasshi., 20, 663 (1973);<br></p>

<p>Applications (S)-Carbidopa Methyl Ester N-cyclohexylideneis an impurity of Carbidopa (C175915), a prodrug inhibitor of aromatic amino acid decarboxylase.<br>References Sletzinger, M., et al.: J. Med. Chem., 6, 101 (1963)<br></p>

<p>Stability Hygroscopic<br>Applications (S)-3-Aminopiperidin-2-one, is an building block , used in the synthesis of various pharmaceutical compounds. It is an intermediate in the synthesis of calpinactam derivatives, possessing antimycobacterial activity.<br>References Kenichiro, N., et al.: Bioorg. Med. Chem. Lett., 22, 7739 (2012);<br></p>

<p>Applications A labelled, essential amino acid.<br>References Goze, C., et al.: Eur. J. Pharmacol., 643, 153 (2010), Bhandare, P., et al.: J. Chem. Pharm. Res., 2, 372 (2010),<br></p>

<p>Applications Benzyl Acetate, is found naturally in many flowers, It has pleasant sweet aroma reminiscent of jasmine, and thus is used widely in perfumery industry, and also as a flavouring agent. It is also used as a solvent.<br>References Schiestl, F. P., et al.: J. Chem. Ecology, 29 (2004); Qian-qian, M., et al.: Jingxi Huagong, 30, 442 (2013);<br></p>

<p>Applications 4-Aminobutyl-d8 Guanidine is the labelled analog of the decarboxylation product of the amino acid arginine (A769500) and also an intermediate in polyamine biosynthesis.<br>References Golding, B.T., et al.: Biochem. Soc. Trans., 22, 391S (1994);<br></p>

<p>Applications Minor Cisapride (C496400) metabolite.<br>References Meuldermans, W., et al.; Drug Metab. Disposition, 16, 410 (1988), Lowry J., et al.; Clin. pharmacol. ther., 73, 209 (2003), Shao L., et al.: Bioorg. Med. Chem. Lett., 19, 5679 (2009),<br></p>