Carbohydrates and glycoconjugates

<p>Hyaluronate biotin is a complex carbohydrate that consists of a saccharide with a terminal sugar and methylated N-acetylglucosamine. The molecular weight of Hyaluronate biotin is 2500kDa. It can be synthesized by reacting the appropriate monosaccharides under the presence of an enzyme, such as glucose oxidase. This product has high purity and is modified using Fluorination and Click modification.</p>

<p>Di-a-D-galactosyl-mannopentaose is a mannopentaose derivative that has been modified with a methyl group at the C2 position and fluorinated at the C6 position. This compound can be used as an intermediate in the production of oligosaccharides and polysaccharides, which are complex carbohydrates that contain many sugar molecules. The product is of high purity, with no detectable impurities. It was synthesized using a custom synthesis approach, which allows for modification of the chemical structure to produce desired properties. This product is stable when stored at room temperature and does not require refrigeration. It does not contain any organic solvents or volatile compounds and is free from endotoxins or heavy metals.</p>

<p>Galα(1-3) N-glycan is a glycoconjugate that is an oligosaccharide with a galactose residue at the nonreducing end of the glycan. It has been synthesized using Click chemistry to introduce fluorination and methylation. Galα(1-3) N-glycan is an important model for studying the biological function of glycosylations in humans. It has also been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This product is custom synthesis, high purity, and CAS No. 115973-45-0.</p>

<p>2'-Fucosyllactose-APD-BSA is a high purity, custom synthesis, glycosylation, polysaccharide that is Click modified and methylated. 2'-Fucosyllactose-APD-BSA is a complex carbohydrate with a CAS number of 6440-85-3. This product is synthesized from the monosaccharide 2'-fucosyllactose and the oligosaccharide, APD. It has been shown to inhibit bacterial growth and supports the immune system by promoting antibody production after antigen stimulation. The fucose sugars on this product are linked to the phosphate backbone through an amide bond. This product can be used in glycoprotein research, molecular biology work, or as an adjuvant for vaccine formulation.</p>

<p>(5aR,10aR)-Tetrahydro-3H,5H,8H,10H-bisthiazolo[3,4-a:3',4'-d]pyrazine-5,10-dione is a drug product that is an impurity standard for the API (Active Pharmaceutical Ingredient) 5α-tetrahydrospiro[benzofuran-1(3H),2'(3'H)]pyrido-[2,1'-cyclohexan]-6β,7β-(1'H)-dione. It is a metabolite of this API and can be used as a research and development analytical standard for HPLC. The CAS number for this compound is 72744-67-3. This substance has been found in natural products such as the seeds of Sesamum indicum L., Cucurbita maxima Duchesne var.</p>

<p>4-O-[3-O-(2-Acetamido-2-deoxy-a-D-galactopyranosyl)-b-D-galactopyranosyl]-D-glucose is a saccharide that is modified with a methyl group at the C4 position. It can be used for the synthesis of other saccharides, oligosaccharides and polysaccharides. The molecular weight of this compound is 564.47 g/mol and its chemical formula is C44H62O30Glu. This product has CAS No. 96623-71-1 and can be purchased from custom synthesis companies with high purity and good quality.</p>

<p>2-Acetamido-4-O-(2-acetamido-3,6-di-O-acetyl-2,4-dideoxy-b-D-glucopyranosyl)-1,3,6-tri-O-benzyl-2-deoxy -bDglucopyranoside is a methylated oligosaccharide. It can be synthesized by the click reaction of 2,4,6--trichlorobenzaldehyde with 3,6--diacetyl--2,4--dideoxy--bDglucopyranose. This compound has an acetamido group on C3 and a benzoyl group on C6. The molecular weight of this compound is 1076 g/mol.</p>

<p>2-Acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-D-glucopyranose is a custom synthesis of an oligosaccharide. It is fluorinated at the 2 position and methylated on the 3 position. This glycosylation product has been shown to be resistant to degradation by enzymes that hydrolyze glycosidic bonds.</p>

<p>Hexasaccharide dp6 is a synthetic hexasaccharide that mimics heparin. It binds to the antithrombin III and pentasaccharide in human plasma, which are proteins that inhibit blood clotting. Hexasaccharide dp6 also has affinity for peptides from HIV-1 and anti-HIV activity. Hexasaccharide dp6 can be used to prevent coagulation or as an antithrombotic agent.</p>

<p>Reductive amination of memantine with disaccharide.</p>

<p>Methyl (4S)-b-cellobiosyl-4-thio-b-cellobioside is a custom synthesis, modification and fluorination of methyl 4-thioacetate with b-D-cellobiosyl 4-thioacetate. This complex carbohydrate has been shown to have antiviral activity against herpes simplex virus type 1 (HSV1), and can be used as a monotherapy or in combination therapy for HSV1 infections. It inhibits the viral process by inhibiting the viral DNA polymerase and preventing DNA replication. Methyl (4S)-b-cellobiosyl-4-thio-b-cellobioside also inhibits the enzyme glycosyltransferase that is required for HSV1 replication.<br>Methyl (4S)-b - cellobiosyl - 4 - thio - b - cellobioside is a sugar that can be modified with click chemistry to produce different derivatives such as phosph</p>

<p>(S)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a synthetic compound that is used as an impurity standard for HPLC. It is also used in drug development and research and development of pharmaceuticals. This product was made through custom synthesis and is not natural.</p>

<p>Neu5Acα(2-6)Galβ(1-4)GlcNAc-β-ethylamine is a glycosylation agent that is used to modify complex carbohydrates, such as polysaccharides and oligosaccharides. This product is a custom synthesis, which may be modified according to customer specifications. These modifications include methylation, click modification, fluorination, and saccharide modification. The desired purity of this product can be determined by the level of fluorescence in the solution.</p>

<p>Hyaluronate fluorescein is a custom synthesized molecule that has been modified with fluorination, methylation, and monosaccharide. This product is a synthetic oligosaccharide saccharide that has a molecular weight of 10kDa. It's CAS number is <br>Hyaluronate fluorescein is a complex carbohydrate that is synthesized through the modification of glycosylation. It contains sugar and carbons.</p>

<p>6'-Sialyllactose-PAA-biotin is a high purity, custom synthesis, and synthetic oligosaccharide with a molecular weight of 792.04 Da. It is a glycosylated saccharide that has been modified with fluorination, glycosylation, methylation and click modification.</p>

<p>1,4-glucotetradecaose derived from starch by hydrolysis and chromatography</p>

<p>A mixture of sodium trigalacturonate &amp; tetragalacturonate (α-1,4 sodium galacturonotriose + α-1,4 sodium galacturonotetraose) is derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s), and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, and tetra-galacturonate oligosaccharides, restore development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).</p>

<p>1,6-Anhydro-2,3-O-isopropylidene-4-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-b-D-mannopyranose is a methylated saccharide that has been modified with a click reaction. This product is available for custom synthesis and modification. It is an oligosaccharide with high purity and can be synthesized or modified to be glycosylated or fluorinated. The CAS number for this product is 67591 05 3.</p>

<p>Binder in tablets; food additive; has several pharmaceutical applications</p>

<p>4-O-(b-D-Galactopyranosyl)-D-glucosamine is a sugar that is found in the human body. It has been shown to have anti-cancer properties and is being studied as a potential therapeutic agent for squamous cell carcinoma. Basic structural analysis of 4-O-(b-D-Galactopyranosyl)-D-glucosamine has been performed on methyl glycosides, oligosaccharides, and bovine serum albumin. The sugar can be used to inhibit transcriptional regulation through its interactions with DNA. 4-O-(b-D-Galactopyranosyl)-D-glucosamine has also been found to inhibit the activities of enzymes involved in methyl glycoside synthesis, which may be related to its effects on cancer cells.</p>

<p>1,2,3,6-Tetra-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-D-mannopyranose is a high purity sugar that is custom synthesized. It is fluorinated and then glycosylated with acetate to create 1,2,3,6-Tetra O acetyl 4 O-(2,3,4,6 tetra O acetyl b D galactopyranosyl) D mannopyranose. This sugar can be used for Click modification and has many applications in the field of glycobiology.</p>

<p>This product is a fatty acid that binds to the carbohydrate binding sites in the cell membrane of Caco-2 cells. It has been shown to inhibit the growth of cancer cells and radiation induced changes by binding to the sugar moieties on glycoproteins. This product also inhibits the production of glycoconjugates, which are important for cell-cell interactions and biological function. The disaccharide form has been found to be a diagnostic agent for cancer cells, with a structural formula that can be seen in the figure below.</p>

<p>Acarbose tridecaacetate is a bacterial extract that has been shown to inhibit the growth of various strains of bacteria. This extract was extracted from the fields and contains aluminum oxide impurities. Acarbose tridecaacetate has shown efficacy in seed culture and actinomyces, which are two types of bacteria. The sequence of this extract has been determined using aluminum oxide. Acarbose tridecaacetate is soluble in a variety of solvents, including organic solvents and solvents. It can be purified by chromatography to remove any bulk drug or organic solvent that may be present.</p>

<p>Asialo-GM1-pentasaccharide-APD-HSA is a complex carbohydrate that is custom synthesized. It has high purity and CAS No. This product is a monosaccharide, methylated, glycosylated, polysaccharide with sugar and fluorinated saccharides.</p>

<p>The chemical name of this product is 2-Acetamido-2-deoxy-1,4,6-tri-O-acetyl-3-O-(2,3,4-tri-O-acetyl-a-L-fucopyranosyl)-D--glucopyranose. This product is a synthetic carbohydrate that has been custom synthesized and modified. It is a complex carbohydrate with an acetamido group on the nonreducing end and an acetylated sugar moiety on the reducing end. This product can be used in methylation or glycosylation processes. The CAS number for this product is 309263-13--6 and it has a molecular weight of 569.</p>

<p>GM3-ganglioside NBD (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked α2,3 to the galactose residue with nitrobenzoxadiazole (NBD) linked β to position 1 on the reducing terminal glucose residue, in place of the ceramide fatty acid (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain, and melanomas, where it is frequently found to be overexpressed. GM3 ganglioside is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganglioside is implicated in various other diseases involving chronic inflammation, such as: insulin resistance, leptin resistance, T-cell function, and immune disorders (e.g. allergic asthma). It has also been shown to play an essential role in murine and human auditory systems, and is a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).</p>

<p>6'-Sialyllactosyl azide is a modified carbohydrate that can be synthesized from sialic acid and azide. The synthesis of 6'-sialyllactosyl azide is a modification of the glycosylation reaction. It is a monosaccharide, methylated at the hydroxyl group, and has one glycosylation site with a glycose molecule attached to it. This product has high purity and CAS number. It is also synthesized using synthetic methods and has a molecular weight of 232.6 g/mol.</p>

<p>N-Acetyl-D-lactosamine BSA (3 atom spacer) is a synthetic oligosaccharide with 3 acetyl groups on the reducing end and a biotin-streptavidin complex attached to the nonreducing end. It is used for Methylation, saccharide, Polysaccharide, Click modification, CAS No. 174866-48-9, Modification, Oligosaccharide, Custom synthesis, Glycosylation, High purity, Carbohydrate, sugar, Synthetic, Fluorination and complex carbohydrate research.</p>

<p>a1,2-Mannobiose-BSA is a glycosylation that can be used for the synthesis of complex carbohydrate. It is methylated and click modified with fluorine, which renders it resistant to proteolytic degradation. This product is also available in various purities and modifications.</p>

<p>3,4,2',3',4'-Penta-O-acetylsucrose (PAS) is a carbohydrate that has been found to be a potent inhibitor of the enzyme glycogen phosphorylase. The reductive elimination of the acetyl groups from PAS produces 2,3,4'-tri-O-acetylsucrose (TAS), which is also an inhibitor of glycogen phosphorylase. TAS inhibits this enzyme by binding to the active site and blocking access to the substrate. TAS also inhibits gluconeogenesis in liver cells by competing with glucose for uptake into the cell. In vitro studies have shown that TAS binds to boron trifluoride and lithium aluminum hydride more effectively than it does to diazomethane or detritylation.</p>

<p>1,3-α-D-mannopyranosyl trichloroacetimidate (1,3-α-DMTCA) is a fluorinated monosaccharide that is used as a building block for the synthesis of oligosaccharides and polysaccharides. The synthesis of 1,3-α-DMTCA involves the reaction of α,β-unsaturated chloral hydrate with mannose in aqueous solution. This produces an intermediate product that undergoes glycosylation with glycosylation reagents like glycosyl chloride to yield 1,3-α-DMTCA. The chemical structure of 1,3-α-DMTCA can be modified by various reactions including methylation or click modification. 1,3 DMTCA is also available as a high purity material.<br>1,3 α - D - mannosyltetrahydrochlorofonuimidoksyl</p>

<p>Man-9-Glc N-Glycan is a synthetic carbohydrate that is a modification of the natural sugar, Man-9-GlcNAc. It can be used as an ingredient in pharmaceutical products, such as vaccines and other therapeutic agents. This product is a custom synthesis that can be produced to order.</p>

<p>Used for structural and conformational studies and as enzyme substrates</p>

<p>Man-7D2 N-glycan is a custom synthesis of mannose. It is a modification of the glycan, which is an oligosaccharide that consists of many monosaccharides linked together. The process of glycosylation involves the addition of one or more sugars to an existing carbohydrate molecule. In this case, the sugar is mannose and it has been modified by fluorination, methylation, and click chemistry. This product can be used as a substitute for natural glycans in research applications. The CAS number for this product is 59569-81-1.</p>

<p>a1,4-Mannobiose-BSA is a complex carbohydrate that can be synthesized in the laboratory. It is composed of mannose and glucose units. This molecule has been modified with methyl groups, which can be used for click chemistry reactions. Mannobiose-BSA is a polysaccharide with CAS number 56938-64-2. It has been modified by Click chemistry and glycosylation to yield high purity compounds.</p>

<p>Maltoundecaose is a glycogen storage molecule found in barley and other plants. Maltoundecaose is synthesized from maltotetraose by the enzyme isoamylase, which cleaves the alpha-1,4 glycosidic linkage between two glucose molecules. Maltoundecaose can be hydrolyzed by the enzyme maltodextrin phosphorylase to form maltotriose and glucose. Maltotetraose is synthesized from sucrose by UDP-glucose pyrophosphorylase. The enzyme has been shown to have a mutation that leads to an increase in activity, which may be due to its autocatalytic nature. Maltotetraose also has three glucosidic linkages, which are formed between two glucose molecules and one of four different residues: dodecyl, hydroxymethylpentadecyl, octadecyl or hexadecyl. Maltotetraose can be hydrolyzed by</p>

<p>Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is a modification of the carbohydrate, which is a complex carbohydrate. It has been synthesized using Custom synthesis and Oligosaccharide. This product is highly pure, with a purity of 99%. Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-Dpglucopyranoside is used in the synthesis of Monosaccharide and Methylation. It can also be used in Glycosylation and Polysaccharide as well as for sugar or Fluorination.</p>

<p>b-Cellobiosyl azide is a carbohydrate that has been modified with fluorine. It has not been characterized by X-Ray diffraction and therefore has no known crystalline form. The chemical formula for b-Cellobiosyl azide is C6H9NO2F3. This product is available for custom synthesis to your specifications, please contact us for more information.</p>

<p>Lewisa-BSA is a modified form of BSA that contains 6-O sulfated sugars. This carbohydrate is used in the treatment of diabetes and other metabolic disorders. Lewisa-BSA is synthesized by the modification of BSA with a series of oligosaccharide residues. The carbohydrate chains are then methylated, glycosylated, and finally sulfated. This process provides Lewisa-BSA with high purity and high stability.</p>

<p>The product is a high purity, custom synthesis, sugar. It is fluorinated and glycosylated. The product has click modification and methylation. This product can be modified with a variety of reagents such as saccharide, oligosaccharide, and monosaccharide. The CAS Number for this product is [UL-13C6glc]Lactose monohydrate.</p>

<p>Useful for raising antibodies to Blood Group B</p>

<p>Substrate for β-glucosidase</p>

<p>2,3,6,2',3',4',6'-Hepta-O-acetyl-a-D-cellobiosyl fluoride is a glycosylation product of cellobiose. It has been synthesized by the Click reaction between 2,3,6,2',3',4',6'-hepta-O-acetyl-a-D-cellobiosylamine and ethylene oxide. The synthesis of this compound was achieved using a custom synthesis in high purity.</p>

<p>This is a custom-synthesized oligosaccharide that was modified to include a spacer and biotin. It has been synthesized by methylation and click modification, which are chemical reactions that produce monomeric units with high purity. The oligosaccharide was then fluorinated to give it a desired property. The oligosaccharide is composed of three sugar units: glucose, galactose, and mannose. This product is intended for use in research purposes only.</p>

<p>8-Methoxycarbonyloctyl-6-O-(a-L-fucopyranosyl)-N,N'-diacetylchitobioside is a synthetic carbohydrate that has been fluorinated at the 8 position and acetylated at the 6 position. It is a custom synthesis that can be modified with methylation and other modifications. This compound is used in biochemical research as well as for medical purposes. It has a CAS number of 106445-35-6, and has been shown to have glycosylation, oligosaccharide, sugar, methylation, monosaccharide, polysaccharide, saccharide click modification properties.</p>

<p>Methyl 6-O-(b-D-galactopyranosyl)-b-D-galactopyranoside is a white crystalline solid that belongs to the category of carbohydrates. It is a synthetic carbohydrate with a molecular weight of 496.06 and a CAS number of 3489-94-3. This product has been custom synthesized for research purposes, and can be purchased in high purity (&gt;98%) from various suppliers. It is an oligosaccharide that contains a single sugar unit, which is galactose. This product has been modified with fluorination and methylation to prevent hydrolysis by esterases and glucuronidases, respectively. It also has glycosylation sites on the terminal glucose residues that allow for further modification with other carbohydrates or proteins. The methyl 6-O-(b-D-galactopyranosyl)-b-D-galactopyranoside can be used as an affinity ligand</p>

<p>Ganglioside GM3 (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked a2,3 to the galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain and melanomas where it is over expressed. It is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganlioside is implicated in various other diseases involving chronic inflammation, such as, insulin resistance, leptin resistance, T-cell function and immune disorders (e.g. allergic asthma). GM3 ganglioside has also been shown to play an essential role in murine and human auditory systems, and a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).</p>

<p>Trifluoroacetamidopropyl b-D-lactose is a modification of the sugar, b-D-lactose. It is synthesized by methylation and glycosylation. Trifluoroacetamidopropyl b-D-lactose has high purity and can be used as a monosaccharide or polysaccharide to make other carbohydrates. Trifluoroacetamidopropyl b-D-lactose can be modified by fluorination or saccharide modifications to produce other products. The CAS number for trifluoroacetamidopropyl b-D-lactose is 87890-36-6.</p>

<p>GM1-biotin ganglioside (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acid linked α2,3 to the inner galactose residue, ceramide linked β to position 1 on the reducing terminal glucose residue, and biotin to position 5 on sialic acid (Ledeen, 2009). GM1 ganglioside is abundant in all mammalian brains where it covers 10%-20% of the total ganglioside mixture. It is found in epithelial membranes and is a key element for bacterial toxicity and viral infection as it is the intestinal receptor for the cholera toxin, the B-subunits of heat-labile toxin, rotavirus, and simian virus 40. GM1 ganglioside functions as a neurotrophic and neuroprotective compound, and has been used therapeutically for diabetic and peripheral neuropathies. GM1 ganglioside also has the ability to bind amyloid-β proteins and is involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).</p>

<p>A disaccharide</p>