Carbohydrates and glycoconjugates

<p>3-O-Acetyl-1,6-anhydro-2-azido-2',3'-di-O-benzyl-4',6'-O-benzylidene-2-deoxy-b,D cellobiose is a fluorinated oligosaccharide that can be customized for a variety of applications. The sugar unit contains an acetyl group on the C1 position and an azido group at the C2 position. This compound has been subjected to click chemistry in order to form a covalent bond with 4,6'-O-benzylidene 2,3'-dideoxy b,D cellobiose.</p>

<p>Gala1-2Gal-HSA is a modified, complex carbohydrate. The carbohydrate is synthesized by methylating, glycosylating and polysaccharide synthesis to produce Gala1-2Gal-HSA. It has CAS No. and can be custom synthesized with high purity. Gala1-2Gal-HSA is a monosaccharide that can be fluorinated or saccharide that can be glycosylated or methylated. Gala1-2Gal-HSA has many applications in the biomedical field such as inhibiting inflammation and preventing cancer metastasis.</p>

<p>3-O-(2-Acetamido-2-deoxy-D-glucopyranosyl)-1,2-di-O-benzyl-4,6-O-benzylidene-D-mannopyranoside is a synthetic sugar that is used in the synthesis of glycosylations. It has been fluorinated and methylated to increase its stability and reactivity. It is also synthetically derived from a saccharide and modified for use in Click chemistry. 3-O-(2-Acetamido-2-deoxy--D--glucopyranosyl)-1,2--di--O--benzyl--4,6--O--benzylidene--D--mannopyranoside is soluble in water and ethanol. This product has CAS No. 5118876–78–3 and can be custom synthesized by us.</p>

<p>Hyaluronate biotin is a high purity and complex carbohydrate. It is synthesized by methylation, saccharide, polysaccharide, and glycosylation of natural hyaluronic acid. Hyaluronate biotin is a modified form of hyaluronic acid that contains an additional biotin molecule per every 500 kDa of molecular weight. This modification can be used in the development of new drugs or as a supplement to improve joint health.</p>

<p>Benzyl 2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-a-D-galactopyranoside is a modification of an oligosaccharide. This product is synthesized by custom synthesis and is available in high purity. It has CAS No. 90754-57-7 and a monosaccharide methylation pattern. This product can be used in the synthesis of complex carbohydrates, as well as glycosylation and polysaccharide synthesis. It can also be used as a sugar or fluorination reagent for saccharides.</p>

<p>Synthetic building block for oligosaccharide synthesis</p>

<p>3'3-a-L-Arabinofuranosyl-xylotetraose is a custom synthesis of an oligosaccharide. It is a polysaccharide that is modified by methylation, glycosylation and carbamoylation. This carbohydrate has been fluorinated at the 3'3 position. The monosaccharide composition of this molecule is erythrose, arabinose and xylose.</p>

<p>Globo-N-tetraose conjugated to HSA with acetyl-phenylenediamine spacer</p>

<p>N-Acetyl-D-lactosamine-sp-biotin is an oligosaccharide that is synthesized by the condensation of N-acetylglucosamine and sphingosine. It is a complex carbohydrate that can be modified with fluorination, monosaccharide, and polysaccharides. N-Acetyl-D-lactosamine-sp-biotin has been shown to have a high purity and can be used in the synthesis of glycosylation, methylation, or click chemistry.</p>

<p>The H-BSA-15-atom spacer is a synthetic polymer that can be modified to create a glycolipid or glycopeptide. The H-BSA-15-atom spacer is an oligosaccharide with a molecular weight of 3,500 daltons and has been custom synthesized for this use. This product is highly purified and does not contain any other substances, such as proteins. It has been fluorinated to increase its resistance to degradation by enzymes. Glycosylation and click modification have also been performed on the H-BSA-15 atom spacer.</p>

<p>Heparin derived dp20 saccharide ammonium salt is a synthetic, high purity, complex carbohydrate that has been modified with fluorination and methylation. It is a polysaccharide composed of repeating units of D-glucosamine and D-mannose, which are linked by alternating alpha 1-6 and alpha 1-4 glycosidic bonds. This product can be used as a monosaccharide or sugar in the synthesis of oligosaccharides or polysaccharides.</p>

<p>Sialyl-Lex-hexa-APD-HSA is a high purity synthetic glycosylation that is custom synthesized. It has been modified with fluorination, methylation, and click modification. Sialyl-Lex-hexa-APD-HSA can be used in the synthesis of complex carbohydrates and is available in CAS Number: 75869-57-3.</p>

<p>Lacto-N-difucohexaose I-APD-HSA is a custom synthesis of an oligosaccharide with a molecular weight of 5,000 Da. It is modified with fluorine and methyl groups at the C6 and C1 positions. Lacto-N-difucohexaose I-APD-HSA is synthesized by click chemistry and has been shown to be effective in inhibiting the growth of cancer cells. This sugar can be modified by glycosylation or carbohydrate modification.</p>

<p>The b-D-Fructofuranosyl-a-D-galactopyranoside is a sugar molecule that is a carbohydrate. It contains sugar phosphates and an aldehyde group. The hydroxyl groups on the molecule can be found on the hydroxyl, ketone, and alcohols that are present. This carbohydrate also has hemiketal and sugar alcohol groups. These molecules have six carbon atoms in their molecular structure with one oxygen atom and one hydrogen atom attached to each of them. The deoxy form of this molecule is not active for DNA synthesis or protein synthesis but it can be used as an intermediate in the production of other sugars such as maltose, cellobiose, and sucrose.</p>

<p>4-O-(2-O-Methyl-b-D-galactopyranosyl)-D-glucopyranose is a disaccharide. The lacto-n-biose unit is a nonreducing sugar that contains an alpha, beta unsaturated 1,6 glycosidic bond and a lactose molecule. 4-O-(2-O-Methyl-b-D-galactopyranosyl)-D-glucopyranose has been found to stimulate the synthesis of galectin in vitro, which may be due to its ability to bind to lectins. This disaccharide can also cause denaturation at high temperatures.</p>

<p>3'-Sialyllactose-APD-HSA is a complex carbohydrate with Oligosaccharide and Polysaccharide. It is a modification of saccharides, which are composed of monosaccharides or simple sugars. 3'-Sialyllactose-APD-HSA is a synthetic compound that has been modified by the addition of fluorine atoms to the sugar molecule. This modification prevents the sugar from being broken down by enzymes in the body and ensures that it remains intact until it reaches its target site. 3'-Sialyllactose-APD-HSA is used as a drug delivery system for cancer drugs, such as doxorubicin and paclitaxel.</p>

<p>GM3-ganglioside NBD (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked α2,3 to the galactose residue with nitrobenzoxadiazole (NBD) linked β to position 1 on the reducing terminal glucose residue, in place of the ceramide fatty acid (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain, and melanomas, where it is frequently found to be overexpressed. GM3 ganglioside is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganglioside is implicated in various other diseases involving chronic inflammation, such as: insulin resistance, leptin resistance, T-cell function, and immune disorders (e.g. allergic asthma). It has also been shown to play an essential role in murine and human auditory systems, and is a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).</p>

<p>3-O-b-D-Galactosylsucrose is a synthetic, fluorinated, high purity, oligosaccharide. It is a complex carbohydrate that contains an O-linked glycosylated monosaccharide. This product has been modified with a click modification. The CAS number for this product is 686717-73-7 and it can be synthesized to order.</p>

<p>Benzyl 2-acetamido-4-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-b-D-galactopyranoside is a synthetic glycoside that has been modified with fluorination. It is an oligosaccharide sugar that has been synthesized from the monosaccharide galactose and the disaccharide maltose. The chemical formula for this compound is C14H22FNO6. This product can be used in custom synthesis or as a research reagent.</p>

<p>Methyl 3-O-(b-D-galactopyranosyl)-b-D-galactopyranoside is a disaccharide that is the residue of 6-fluoro-3-indoxyl beta-D-galactopyranoside. This product is a glycoside of methyl 3,6,3',6'-tetraacetate and b-D-galactose.</p>