Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
At CymitQuimica, we offer high-purity benzimidazoles and imidazoles for research in medicinal chemistry, pharmacology, and biotechnology.
Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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5-(chloromethyl)-1-hexyl-2-methanesulfonyl-1H-imidazole
CAS:Formula:C11H19ClN2O2SPurity:95.0%Molecular weight:278.8(S)-BENZYL 4-METHYL-2,5-DIOXOOXAZOLIDINE-3-CARBOXYLATE
CAS:Formula:C12H11NO5Purity:97.0%Color and Shape:SolidMolecular weight:249.222N-[3-(1-IMIDAZOLYL)PROPYL]-4-CHLOROBENZENESULFONAMIDE
CAS:Formula:C12H14ClN3O2SPurity:>97%Molecular weight:299.775-(4-Methoxy-phenyl)-1H-tetrazole
CAS:Formula:C8H8N4OPurity:95.0%Color and Shape:SolidMolecular weight:176.1791-Cyclopropyl-1H-imidazole
CAS:Formula:C6H8N2Purity:≥95%Color and Shape:LiquidMolecular weight:108.1441H-Benzimidazole-2-methanol
CAS:Formula:C8H8N2OPurity:97%Color and Shape:Chunks,Crystalline PowderMolecular weight:148.165(1-Methyl-1H-imidazol-2-yl)methanol
CAS:Formula:C5H8N2OPurity:97%Color and Shape:SolidMolecular weight:112.1325-Bromo-2-(chloromethyl)-1H-1,3-benzodiazole hydrochloride
CAS:Formula:C8H7BrCl2N2Purity:97%Molecular weight:281.964-(5-Methyl-1H-tetrazol-1-yl)aniline
CAS:Formula:C8H9N5Purity:95.0%Color and Shape:SolidMolecular weight:175.195[2-(1H-imidazol-2-yl)ethyl]amine dihydrochloride
CAS:Formula:C5H11Cl2N3Purity:98%Color and Shape:SolidMolecular weight:184.06Pramiracetam Sulfate
CAS:<p>Thurfyl salicylate is a reddening agent for the treatment of musculoskeletal, joint, periarticular, and soft tissue pain.</p>Formula:C14H29N3O6SColor and Shape:SolidMolecular weight:367.46Butoconazole
CAS:<p>Butoconazole (1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole) is an imidazole antifungal agent</p>Formula:C19H17Cl3N2SPurity:99.33% - 99.65%Color and Shape:SolidMolecular weight:411.78Luxabendazole
CAS:<p>Luxabendazole: broad-spectrum anthelmintic effective on various worm stages.</p>Formula:C15H12FN3O5SColor and Shape:SolidMolecular weight:365.34(2Z)-2-[Cyano(2,3-dichlorophenyl)methylene]hydrazinecarboximidamide
CAS:Controlled ProductFormula:C9H7Cl2N5Color and Shape:NeatMolecular weight:256.09Isometronidazole-D4
CAS:Controlled Product<p>Applications Isometronidazole-D4 is a labelled analogue of Isometronidazole (I821342). Isometronidazole is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.<br>References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)<br></p>Formula:C6D4H5N3O3Color and Shape:NeatMolecular weight:175.182-(Chloromethyl)-4-methoxy-3,5-dimethylpyridine Hydrochloride
CAS:Controlled Product<p>Impurity Omeprazole EP Impurity XI<br>Applications 2-(Chloromethyl)-4-methoxy-3,5-dimethylpyridine Hydrochloride (Omeprazole EP Impurity XI) is an intermediate in the production of the antiulcer agent Omeprazole.<br>References Roma, G., et al.: J. Med. Chem., 50, 2886 (2007), Hoffmann, S., et al.: Toxicol. Lett., 180, 9 (2008),<br></p>Formula:C9H12ClNO·ClHColor and Shape:WhiteMolecular weight:222.11(3S)-1-[2-(3-Ethenyl-4-hydroxyphenyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide
CAS:Controlled ProductFormula:C28H30N2O2Color and Shape:NeatMolecular weight:426.55(S)-5,6-Dehydro Pregabalin
CAS:Controlled Product<p>Applications (S)-5,6-Dehydro Pregabalin is derived from rac 5,6-Dehydro Pregabalin (D230055), which is an impurity of the anti-convulsant, Pregabalin (P704800).<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>Formula:C8H15NO2Color and Shape:NeatMolecular weight:157.21Lurasidone Opened Imide (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Lurasidone Opened Imide is an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia.<br>References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008);<br></p>Formula:C28H38N4O3SColor and Shape:NeatMolecular weight:510.69rac N-Demethyl Promethazine-d3 Hydrochloride
CAS:Controlled Product<p>Applications Labelled Promethazine (P757000) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keipert, S., et al.: Pharmazie, 31, 296 (1976),<br></p>Formula:C16H16D3ClN2SColor and Shape:NeatMolecular weight:309.878-Demethyl Zolazepam
CAS:Controlled Product<p>Applications N-Demethylated metabolite of the anesthetic agent, Zolazepam (Z613500).<br>References Baukema, J. et al.: Res. Comm. Chem. Pathol. Pharmacol., 10, 227 (1975);<br></p>Formula:C14H13FN4OColor and Shape:NeatMolecular weight:272.28Varenicline-d2,15N2 Dihydrochloride
CAS:Controlled Product<p>Applications Varenicline-d2,15N2 Dihydrochloride, is the labelled dihydrochloride salt of Varenicline (V098492), a nicotinic α4β2 acetylcholine receptor partial agonist. Aids in smoking cessation.<br>References Benowitz, N., et al.: Clin. Pharmacol. Ther., 44, 23 (1988), Cohen, C., et al.: J. Pharmacol. Exp. Ther., 306, 407 (2003), Tapper, A., et al.: Science, 306, 1029 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Obach, R., et al.: Drug Metab. Disp., 34, 121 (2006),<br></p>Formula:C13H13D2Cl2N15N2Color and Shape:Light Beige SolidMolecular weight:288.18Trimebutine EP Impurity E-Nitroso
Controlled ProductFormula:C21H26N2O6Color and Shape:NeatMolecular weight:402.441(3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl Acetate
CAS:Controlled Product<p>Impurity Lansoprazole<br>Applications (3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl Acetate is an impurity of Lansoprazole (L175000). Lansoprazole is used as a gastric proton pump inhibitor and an antiulcerative. It May limit the severity of tuberculosis.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000); Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001); Barradell, L.B., et al.: Drugs, 44, 225 (1992); Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002); Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006); Chem. and Eng. News. p. 28 July 20 (2018)<br></p>Formula:C11H12F3NO3Color and Shape:NeatMolecular weight:263.2132-Cyclopropylmethylamino-5-chlorobenzophenone
CAS:Controlled Product<p>Applications: 2-Cyclopropylmethylamino-5-chlorobenzophenone is a benzodiazepine derivative.<br>References Japp, M. et al.: J. Chrom., 439, 317 (1988); Guan, F. et al.: J. Anal Toxicol., 23, 54 (1999);<br></p>Formula:C17H16ClNOColor and Shape:NeatMolecular weight:285.77Tofenacin Hydrochloride Salt-d4
CAS:Controlled Product<p>Applications A labelled metabolite of Orphenadrine (O695300). An antidepressant prodrug.<br>References Watkins, P., et al.: J. Biol. Chem., 261, 6264 (1986), McNeil, C., et al.: Biochem. Pharmacol., 51, 15 (1996), Hiessbock, R., et al.: J. Med. Chem., 42, 1921 (1999),<br></p>Formula:C17H18D4ClNOColor and Shape:NeatMolecular weight:295.84Hydroxy Varenicline N-Trifluoroacetic Acid Salt
CAS:Controlled Product<p>Applications Protected Varenicline metabolite.<br></p>Formula:C15H12F3N3O2Color and Shape:NeatMolecular weight:323.274-Fluorobenzonitrile
CAS:Controlled Product<p>Applications 4-Fluorobenzonitrile is used in the synthesis of flurenones, pharmaceutical prerequisites, as well as opiod receptor antagonists.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wan, J. et al.: Org. Lett., 15, 2742 (2013); Kormos, C. et al.: J. Med. Chem., 56, 4551 (2013);<br></p>Formula:C7H4FNColor and Shape:NeatMolecular weight:121.11(S)-Aclidinium Bromide
CAS:Controlled Product<p>Applications (S)-Aclidinium Bromide is an isomer of Aclidinium Bromide (A190180) a novel long-acting antimuscarinic bronchodilator in phase II clinical trials for the treatment of chronic obstructive pulmonary disease (1,2).<br>References (1) Gupta, V. and Singh, D.: Expert Rev Respir Med. 6, 581 (2012)(2) De La Motte, S., et al.: Int. J. Clin. Pharmacol. Therap., 50,403 (2012)<br></p>Formula:C26H30BrNO4S2Color and Shape:Off-WhiteMolecular weight:564.55(S)-Rivastigmine
CAS:<p>Applications S-Rivastigmine is an isomer of Rivastigmine ( an acetylcholinesterase inhibitor used in the treatment of neurological disorders such as Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Howes, L et al.: Drug. Safe., 37, 391 (2014); Shahar, O. et al.: Nucl. Acids Res., 42, 5869 (2014);<br></p>Formula:C14H22N2O2Color and Shape:ColourlessMolecular weight:250.34Butyl Itraconazole
CAS:Controlled ProductFormula:C35H38Cl2N8O4Color and Shape:NeatMolecular weight:705.634-Chloro-6-ethyl-5-fluoropyrimidine
CAS:Controlled Product<p>Applications A pyrimidine derivative used as a building block in the preparation of bio-active compounds such as broad-spectrum triazole antifungal agents.<br>References Butters, M. et al.: Org. Proc. Res. Dev., 5, 28 (2001); Tong, L. et al.: Zhong. Yao., 8, 280 (2010);<br></p>Formula:C6H6ClFN2Color and Shape:NeatMolecular weight:160.58Midazolam-d6 (1 mg/mL in Acetonitrile)
CAS:Controlled ProductFormula:C18D6H7ClFN3Color and Shape:Single SolutionMolecular weight:331.805,6-Dimethoxyindane-1,3-dione
CAS:Controlled ProductFormula:C11H10O4Color and Shape:NeatMolecular weight:206.194-Acetoxy Midazolam
CAS:Controlled Product<p>Applications A metabolite of Midazolam (M343000).<br></p>Formula:C20H15ClFN3O2Color and Shape:NeatMolecular weight:383.802-Chloromethyl-4-methoxy-3-methylpyridine Hydrochloride
CAS:Controlled Product<p>Applications A pyridine derivative used in the preparation of anti-ulcerative agents and other pharmaceutical compounds.<br>References Kuehler, T.C. et al.: J. Med. Chem., 38, 4906 (1995);<br></p>Formula:C8H10ClNO·ClHColor and Shape:NeatMolecular weight:208.08Metopimazine
CAS:<p>Applications Metopimazine (MPZ) is used to prevent emesis during chemotherapies. Antiemetic.<br>References Catz, P., et al.: Int. J. Pharm., 58, 93 (1990), Sato, K., et al.: J. Pharm. Sci., 80, 104 (1991), Herrstedt, J., et al.: Cancer Chemother. Pharmacol., 33, 53 (1996), Sigsgaard, T., et al.: J. Clin. Onc., 19, 2091 (2001),<br></p>Formula:C22H27N3O3S2Color and Shape:Off White SolidMolecular weight:445.60Itraconazole Desethylene-seco-piperazine Di-N-formyl Impurity
CAS:Controlled Product<p>Applications Itraconazole Desethylene-seco-piperazine Di-N-formyl Impurity is a by-product in the synthesis of Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity (I937520), which is an impurity of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C35H36Cl2N8O6Color and Shape:NeatMolecular weight:735.62Solifenacin EP Impurity A Nitroso Impurity
Controlled ProductFormula:C15H14N2OColor and Shape:NeatMolecular weight:238.29β-Ketoglutaric Acid
CAS:<p>Stability Unstable in Solution<br>Applications β-Ketoglutaric Acid is used in the synthesis of benzodiazepine derivatives. Also used in the synthesis of orally available hepatitis C virus polymerase inhibitors.<br>References Jung, D. et al.: Synth. Comm., 29, 1941 (1999); Li, H. et al.: J. Med. Chem., 52, 1255 (2009);<br></p>Formula:C5H6O5Color and Shape:Off White PowderMolecular weight:146.098Omeprazole Sodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Omeprazole Sodium Salt is the salt analogue of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H18N3O3S·Na·H2OColor and Shape:Off-WhiteMolecular weight:385.412-(Chloromethyl)-3,5-dimethylpyridine Hydrochloride
CAS:Controlled Product<p>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Formula:C8H10ClN·ClHColor and Shape:NeatMolecular weight:192.094-Methyl-2-[3-[(1-methylethyl)nitrosoamino]-1-phenylpropyl]phenol
CAS:Controlled ProductFormula:C19H24N2O2Color and Shape:NeatMolecular weight:312.41ent-Voriconazole
CAS:Controlled Product<p>Impurity Voriconazole EP Impurity D; Voriconazole USP Related Compound B<br>Applications ent-Voriconazole (Voriconazole USP Related Compound B; Voriconazole EP Impurity D) is the (2S,3R) enantiomer in Voriconazole (V760000) drug substance.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gage, R., et al.: J. Pharm. Biomed. Anal., 17, 1449 (1998), Owens, P., et al.: Enantiomer, 4, 79 (1999), Pehourcq, F., et al.: Biomed. Chromatogr., 18, 719 (2004), Sellers, J., et al.: J. Pharm. Biomed. Anal., 41, 1088 (2006),<br></p>Formula:C16H14F3N5OColor and Shape:NeatMolecular weight:349.31Metopimazine-d6
CAS:Controlled Product<p>Applications Labelled Metopimazine (MPZ) is used to prevent emesis during chemotherapies. Antiemetic.<br>References Catz, P., et al.: Int. J. Pharm., 58, 93 (1990), Sato, K., et al.: J. Pharm. Sci., 80, 104 (1991), Herrstedt, J., et al.: Cancer Chemother. Pharmacol., 33, 53 (1996), Sigsgaard, T., et al.: J. Clin. Onc., 19, 2091 (2001),<br></p>Formula:C22H21D6N3O3S2Color and Shape:NeatMolecular weight:451.642-(Ethylthio)ethanol
CAS:Controlled Product<p>Applications 2-(Ethylthio)ethanol is used to prepare aryldihydropyrimidinones as inhibitors of fatty acid transporter FATP4.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Blackburn, C., et al.: Bioorg. Med. Chem. Lett., 16, 3504 (2006)<br></p>Formula:C4H10OSColor and Shape:NeatMolecular weight:106.194-Hydroxy Midazolam-d5 Methanoate
CAS:Controlled Product<p>Applications A labelled metabolite of Midazolam (M343000).<br>References Ha, H., et al.: Ther. Drug Monit., 15, 338 (1993), Thummel, K., et al.: J. Pharmacol. Exp. Ther., 271, 557 (1994), Kim, R., et al.: Pharm. Res., 16, 408 (1999), Maurer, H., et al.: Anal. Bioanal. Chem., 381, 110 (2005), Smink, B., et al.: J. Anal. Toxicol., 30, 478 (2006),<br></p>Formula:C19H12D5ClFN3O2Color and Shape:NeatMolecular weight:378.84Voriconazole-d3 N-Oxide (~90%)
CAS:Controlled ProductFormula:C16D3H11F3N5O2Purity:~90%Color and Shape:NeatMolecular weight:368.33(R)-1-Methyl-3-pyrrolidinol
CAS:Controlled Product<p>Applications (R)-1-Methyl-3-pyrrolidinol is a useful synthetic intermediate. It is used for asymmetric synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.<br>References Isakovic, L., et al.: Bioorg. Med. Chem. Lett., 19, 2742 (2009); Gobbini, M., et al.:J. Med. Chem., 51, 4601 (2008)<br></p>Formula:C5H11NOColor and Shape:NeatMolecular weight:101.1510-Chloro Carbamazepine
CAS:<p>Applications 10-Chloro Carbamazepine is a derivative of Carbamazepine (C175840) which is used in treatment of pain associated with trigeminal neuralgia.<br>References Stenger, E.G., et al.: Med. Exp., 11, 191 (1964), Pynnonen, S., et al.: Ther. Drug Monit., 1, 409 (1979), Sidebottom, A., et al.: J. Clin. Pharm. Ther., 20, 31 (1995)<br></p>Formula:C15H11ClN2OColor and Shape:White PowderMolecular weight:270.71Scopolamine Sulfate
CAS:Controlled Product<p>Applications Scopolamine Sulfate is an impurity of Scopolamine (S200000), an acetylcholine antagonist used in the treatment of motion sickness and also used as antiemetic, antispasmodic, mydriatic, preanesthetic agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Trendelenburg P., et al.: Archiv fuer Exper. Pathol. Pharmacol., 73, 118 (1914);<br></p>Formula:C17H21NO7SColor and Shape:NeatMolecular weight:383.422,4-Dicyano-3-(2-methylpropyl)-pentanediamide (Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygrscopic<br>Applications 2,4-Dicyano-3-(2-methylpropyl)-pentanediamide is an impurity of Pregabalin (P704800), a GABA (A602920) analogue used as an anticonvulsant.<br>References Hoekstra, M.S., et al.: Org. Proc. Rec. Deve., 1, 26 (1997); Lowry, O., et al.: J. Biol. Chem., 193, 265 (1951); Gerlach, M., et al.: Brain Res., 741, 142 (1996); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C11H16N4O2Color and Shape:NeatMolecular weight:236.27Propyl Itraconazole
CAS:Controlled ProductFormula:C34H36Cl2N8O4Color and Shape:NeatMolecular weight:691.611,2-Bismethylenecyclohexane (~75%)
CAS:Controlled ProductFormula:C8H12Purity:~75%Color and Shape:NeatMolecular weight:108.183-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane Bromide
CAS:Controlled Product<p>Applications 3-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane is an impurity in the synthesis of Clidinium Bromide (C576250), an anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Formula:C8H16BrNOColor and Shape:NeatMolecular weight:222.122,5-Dichlorobenzoyl Cyanide
CAS:Controlled Product<p>Applications 2,5-Dichlorobenzoyl Cyanide is a reagent applied for research purposes<br>References Veerareddy, A., et al.: J. Heterocyclic Chem., 51, 1311 (2014)<br></p>Formula:C8H3Cl2NOColor and Shape:NeatMolecular weight:200.0222-(2-Butyl)-4-{4-[4-(4-methyloxy-phenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one
CAS:Controlled Product<p>Impurity Itraconazole EP Impurity A<br>Applications 2-(2-Butyl)-4-{4-[4-(4-methyloxy-phenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one (Itraconazole EP Impurity A) is an intermediate of Itraconazole.<br></p>Formula:C23H29N5O2Color and Shape:BeigeMolecular weight:407.512-Amino-5-benzoyl-1-methylbenzimidazole
CAS:Controlled Product<p>Applications Mebendazole (M200500) thermal decomposition product. Mebendazole impurity.<br>References Himmelreich, M., et al.: Aus. J. Pharmaceut. Sci., 6, 123 (1977),<br></p>Formula:C15H13N3OColor and Shape:NeatMolecular weight:251.28Lansoprazole Sulfone N-Oxide
CAS:Controlled Product<p>Applications An impurity of Lansoprazole.<br>References Barradell, L., et al.: Drugs, 44, 225 (1992), Aydogmus, Z., et al.: Acta Pharm. Sci., 48, 45 (2006), El-Sherif, Z., et al.: Chem. Pharm. Bull., 54, 814 (2006),<br></p>Formula:C16H14F3N3O4SColor and Shape:WhiteMolecular weight:401.36N-Nitroso Aryl Lurasidone
CAS:Controlled ProductFormula:C11H12N4OSColor and Shape:NeatMolecular weight:248.313-Isobutylglutaric Anhydride
CAS:Controlled ProductFormula:C9H14O3Color and Shape:NeatMolecular weight:170.20572,5-Dichlorothiophen-3-yl Tioconazole Hydrochloride
CAS:Controlled ProductFormula:C16H12Cl4N2OS·ClHColor and Shape:NeatMolecular weight:458.62N-Nitroso Albendazole (mixtures of regional isomers)
Controlled ProductFormula:C13H16N4O3SColor and Shape:NeatMolecular weight:616.7122,2'-Ethylenedianiline
CAS:Controlled Product<p>Applications 2,2'-Ethylenedianiline is used as a reagent to synthesize Oxcarbazepine (O869250), a broad-specturm, second-generation anticonvulsant drug that is used to treat partial and complex partial seizures in children and adults. 2,2'-Ethylenedianiline is also used as a reagent to prepare a series of triterpines (e.g. Lupeol [L474850]), compounds that have chemopreventative activity.<br>References Asmaa, M., et al.: Pac. J. Cancer Prevent., 15, 475 (2014); Kalis, M. & Huff, N.: Clin. Ther., 23, 680 (2001); Malke, S., et al.: Pharm. Sci., 69, 211 (2007); Schmidt, D. & Elger, C.: Epil. Beh., 5, 627 (2004)<br></p>Formula:C14H16N2Color and Shape:NeatMolecular weight:212.29Metronidazole β-D-Glucuronide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Metronidazole.<br>References Kokwaro, G.O., et al.: Biochem. Pharmacol., 45, 1243 (1993), Sidelmann, U.G. , et al.: Xenobiotica, 26, 709 (1996),<br></p>Formula:C12H17N3O9Color and Shape:NeatMolecular weight:347.286-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline
CAS:Controlled Product<p>Applications 6-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline is a photochemical decomposition product of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Anderson, R., et al.: J. Pharma. Biomed. Anal., 13, 667 (1995); Anderson, R., et al: Am. Clin. Lab., 16, 25 (1997);<br></p>Formula:C15H10ClFN2Color and Shape:NeatMolecular weight:272.701-Chloro-2-(dichlorophenylmethyl)benzene
CAS:Controlled Product<p>Applications 1-Chloro-2-(dichlorophenylmethyl)benzene is an intermediate used in the preparation of 2-chlorotrityl chloride resins. 1-Chloro-2-(dichlorophenylmethyl)benzene is an impurity of the antifungal agent Clotrimazole (C587400).<br>References Li, P. et al.: Guoch. Gong. Xue., 9, 558 (2009);<br></p>Formula:C13H9Cl3Color and Shape:Light YellowMolecular weight:271.57Varenicline Carbamoyl β-D-Glucuronide
CAS:Controlled Product<p>Applications A metabolite of Varenicline.<br>References Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005), Obach, R., et al.: Drug Metab. Dispos., 33, 262 (2005),<br></p>Formula:C20H21N3O8Color and Shape:NeatMolecular weight:431.44-Hydroxy Triazolam
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications A metabolite of Triazolam (T767380).<br>References Gall, M., et al.: J. Med. Chem., 21, 1290 (1978), Jones, H., et al.: Drug Metab. Dispos., 32, 973 (2004), Hallifax, D., et al.: Drug Metab. Dispos., 33, 1852 (2005).<br></p>Formula:C17H12Cl2N4OColor and Shape:NeatMolecular weight:359.21N-Nitrosoiminodibenzyl
CAS:Controlled ProductFormula:C14H12N2OColor and Shape:NeatMolecular weight:224.264-Nitro-5-desnitro Tinidazole
CAS:Controlled Product<p>Impurity Tinidazole EP Impurity B<br>Applications 4-Nitro-5-desnitro Tinidazole (Tinidazole EP Impurity B) is an impurity in the synthesis of Tinidazole (T443900), antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.<br>References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),<br></p>Formula:C8H13N3O4SColor and Shape:NeatMolecular weight:247.27Nitroguanidine (Wetted with water >20%)
CAS:Controlled Product<p>Applications Nitroguanidine is used in the prediction of heats of detonation of energetic compounds from their molecular structure. It is also used in the synthetic preparation of imidacloprid-d4 (I274992), which is a neonicotinoid.<br> E0<br>References Keshavarz, M.H., et al.: Propellant, Explosives, Pyrotechnics, 37, 93 (2012); Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:CH4N4O2Color and Shape:White To Off-WhiteMolecular weight:104.074'-Desmethoxy Omeprazole
CAS:Controlled Product<p>Applications 4'-Desmethoxy Omeprazole is one of two impurities in the synthesis of Esomeprazole, an anti-ulcerative drug for treatment of acid-related diseases.<br>References Liu, X., et al.: Lat. Am. J. Pharm., 34, 1265-1268 (2015);<br></p>Formula:C16H17N3O2SColor and Shape:NeatMolecular weight:315.39(S)-Modafinil-d10
CAS:Controlled Product<p>Applications Labelled (S)-Modafinil. Used for treatment of excessive sleepiness, α1-adrenoceptor agonist.<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999), Purnell, M., et al.: J. Sleep Res., 11, 219 (2002), Dinges, D., et al.: Curr. Med. Res. Opin., 22, 159 (2006)<br></p>Formula:C15D10H5NO2SColor and Shape:NeatMolecular weight:283.412-Aminobenzimidazole
CAS:Controlled ProductFormula:C7H7N3Color and Shape:BeigeMolecular weight:133.15N-Desethyl N-Methyl Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity B<br>Applications N-Desethyl N-Methyl Rivastigmine (Rivastigmine EP Impurity B) is an impurity of Rivastigmine (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C13H20N2O2Color and Shape:NeatMolecular weight:236.32(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
CAS:Controlled ProductFormula:C13H15F2N3O4SColor and Shape:NeatMolecular weight:347.34N-Ethylcarbamic Acid 3-[(1S)-1-(Dimethylamino)ethyl]phenyl Ester
CAS:Controlled ProductFormula:C13H20N2O2Color and Shape:NeatMolecular weight:236.31Isopropyl Itraconazole
CAS:Controlled ProductFormula:C34H36Cl2N8O4Color and Shape:NeatMolecular weight:691.614,4'-(Bromomethylene)dibenzonitrile
CAS:Controlled Product<p>Applications 4,4'-(1-Bromomethyl)bis-benzonitrile (CAS# 69545-39-7) is a useful research chemical compound.<br></p>Formula:C15H9BrN2Color and Shape:NeatMolecular weight:297.1494,9-Diisobutyl-1,6-diazecane-2,7-dione
CAS:Controlled Product<p>Applications 4,9-Diisobutyl-1,6-diazecane-2,7-dione is in impurity of rac-Pregabalin (P704800) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C16H30N2O2Color and Shape:NeatMolecular weight:282.42N-Desethyl N-Methyl rac-Rivastigmine
CAS:<p>Impurity Rivastigmin USP Related Compound B<br>Applications N-Desethyl N-Methyl rac-Rivastigmine (Rivastigmin USP Related Compound B) is an impurity in the synthesis of Rivastigmine (R541000) a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C13H20N2O2Color and Shape:Clear ColourlessMolecular weight:236.31Noratropine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Atropine (A794625). Two metabolites of Atropine (apoatropine and noratropine) were found in rat urine.<br>References Xu, A., et al.: J. Pharm. Biomed. Anal., 14, 33 (1995), Cherkaoui, S., et al.: J. Pharm. Biomed. Anal., 17, 1167 (1998),<br></p>Formula:C16H21NO3·HClColor and Shape:BrownMolecular weight:311.80Modafinil-d5 Sulfone
CAS:Controlled Product<p>Applications A labelled metabolite of Modafinil (M482500), a central nervous system vigilance promoting agent, which possesses neuroprotective properties.<br>References Wong, Y., et al.: J. Clin. Pharmacol., 39, 281 (1999), Robertson, P., et al.: Drug Metab. Dispos., 28, 664 (2000), Roth, T., et al.: Clin. Ther., 28, 689 (2006),<br></p>Formula:C152H5H10NO3SColor and Shape:NeatMolecular weight:294.38
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