Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10433 products of "Benzimidazole and Imidazole Derivatives"
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N-Nitroso Glycopyrrolate Impurity 29
CAS:Formula:C17H22N2O4Color and Shape:White To Off-White SolidMolecular weight:318.37Ornidazole Impurity 11
CAS:Formula:C6H6ClN3O3Color and Shape:Pale Yellow SolidMolecular weight:203.58Atropine EP Impurity E (Mixture of Diastereomers) (7-Hydroxyhyoscyamine)
CAS:Formula:C17H23NO4Molecular weight:305.38Isavuconazole Impurity 12 Chloride DiHCl (Mixture of Diastereomers)
Formula:C37H39F2N8O6S·Cl·2HClMolecular weight:761.83 35.45 2*36.46Rufinamide-5-Carboxamide
CAS:Controlled Product<p>Applications Rufinamide-5-Carboxamide is an impurity of Rufinamide (R701550) which is an antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H8F2N4OColor and Shape:NeatMolecular weight:238.19Metconazole
CAS:<p>Applications Metconazole is a conazole based fungicide used for the control of black sigatoka disease on bananas. Metconazole acts primarily as an inhibitor of ergosterol biosynthesis which interferes with the synthesis of fungal cell membranes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cools, H.J., et al.: Pest. Manage. Sci., 68, 1034 (2012); Nam, M.H., et al.: Res. Plant. Disease., 17, 295 (2011);<br></p>Formula:C17H22ClN3OColor and Shape:White To Off-WhiteMolecular weight:319.83Scopine Di(2-thienylglycolate)
CAS:<p>Impurity Tiotropium EP Impurity B<br>Applications Scopine Di(2-thienylglycolate) (Tiotropium EP Impurity B) is a precursor to Tiotropium Bromide.<br>References Buchwald, P., et al.: Pharmazie., 55, S210 (2000),<br></p>Formula:C18H19NO4S2Color and Shape:NeatMolecular weight:377.48Scopine Methobromide
CAS:<p>Impurity Tiotropium EP Impurity G<br>Applications Scopine Methobromide (Tiotropium EP Impurity G) is an impurity of Tiotropium (T444850), an muscarinic receptor antagonist and bronchodilator.<br>References Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006)<br></p>Formula:C9H16NO2·BrColor and Shape:Off-WhiteMolecular weight:250.13PD 169,316
CAS:<p>M02298 - PD 169,316</p>Formula:C20H13FN4O2Purity:>98%Color and Shape:SolidMolecular weight:360.3479919433594Omeprazole Sulfide
CAS:Controlled ProductFormula:C17H19N3O2SColor and Shape:White To Light BrownMolecular weight:329.422,3-Diphenyl-5-(thiophen-2-yl)-2H-tetrazol-3-ium chloride
CAS:Purity:98%Molecular weight:340.8299865722656Desnitro-imidacloprid Hydrochloride
CAS:Controlled ProductFormula:C9H11ClN4·ClHColor and Shape:Light Orange GreyMolecular weight:247.12Thiabendazole
CAS:Controlled Product<p>Applications A drug used in the treatment of helminthiases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tocco, D.J., et al.: J. Med. Chem., 7, 399 (1964), Robinson, H.J., et al.: Toxicol. Appl. Pharmacol., 7, 53 (1965), Kates, K.C., et al.: J. Parasitol., 57, 356 (1971), Kapoor, V.K., et al.: Anal. Profiles Drug Subs., 16, 611 (1986),<br></p>Formula:C10H7N3SColor and Shape:NeatMolecular weight:201.25Letrozole-d4 (major)
CAS:Controlled ProductFormula:C17D4H7N5Color and Shape:Yellowish SolidMolecular weight:289.332,3,5-Trimethylpyridine N-Oxide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Formula:C8H11NOColor and Shape:Off-White To Light BrownMolecular weight:137.18Rivastigmine-d4 Tartrate Salt
CAS:Controlled Product<p>Applications Rivastigmine-d4 Tartrate Salt, is the labeled analogue of Rivastigmine Tartrate Salt (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C18H24D4N2O8Color and Shape:NeatMolecular weight:404.451’-Hydroxy Midazolam
CAS:Controlled Product<p>Applications A metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Midazolam is also a positive allosteric modulator of the GABAA receptor.<br>References Dundee, J., et al.: Drugs, 28, 519 (1984), Galetin, A., et al.: Drug Metab. Dispos., 30, 1512 (2002), Uchaipichat, V., et al.: Drug Metab. Dispos., 34, 449 (2006), Lewis, B., et al.: Biochem. Pharmacol., 73, 1463 (2007), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3OColor and Shape:Off-WhiteMolecular weight:341.77N-Methyl Omeprazole (Mixture of isomers with the methylated nitrogens of imidazole)
CAS:Controlled Product<p>Applications Omeprazole (O635000) impurity.<br>References Allenmark, S., et al.: Anal. Biochem., 136, 293 (1984), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997),<br></p>Formula:C18H21N3O3SColor and Shape:Off White SolidMolecular weight:359.44rel-(1R,3S,5S)-8-Methyl-8-azabicyclo[3,2,1]oct-6-en-yl-2-hydroxy-2,2-dithiophen-2-yl acetate
CAS:Controlled Product<p>Impurity Tiotropium EP impurity D<br>Applications (1R,3S,5S)-8-Methyl-8-azabicyclo[3,2,1]oct-6-en-yl-2-hydroxy-2,2-dithiophen-2-ylacetate is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.<br>References Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);<br></p>Formula:C18H19NO3S2Color and Shape:NeatMolecular weight:361.481-(Tetrahydro-2H-pyran-2-yl)-1H-indazol-4-amine
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:217.272003173828121-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester (>90%)
<p>Impurity Fesoterodine Impurity 6;<br>Applications 1-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester is derived from (R)-Fesoterodine Fumarate (F321300), which is a muscarinic receptor antagonist for the treatment of Lower Urininary Tract Symptoms (LUTS). It is very similar to Tolterodine (T535800).<br>References Rogers, D., et al.: Pharmacotherapy, 20, 1092 (2000), Praharaj, S., et al.: J. Psychopharmacology, 19, 426 (2005),<br></p>Formula:C26H35NO5Purity:>90%Color and Shape:NeatMolecular weight:441.56Hydroxy Metronidazole
CAS:<p>Applications A metabolite of Metronidazole (M338880).<br>References Haller, I., et al.: Antimicrob. Agents Chemother., 22, 165 (1982), Gibson, R., et al.: Clin. Chem., 30, 784 (1984), Kuti, J., et al.: Pharmacotherapy, 25, 935 (2005),<br></p>Formula:C6H9N3O4Color and Shape:WhiteMolecular weight:187.152,3-Bis(4-ethylphenyl)-5-phenyl-2H-tetrazol-3-ium chloride
CAS:Purity:98%Molecular weight:390.9200134277344Omeprazole-d3 Sulfide
CAS:Controlled ProductFormula:C172H3H16N3O2SColor and Shape:NeatMolecular weight:332.44Tropicamide
CAS:<p>Applications Ophthalmic anticholinergic. Mydriatic.<br>References Blessel, K.W., et al.: Anal. Profiles Drug Subs., 3, 565 (1974), Krapivinsky, G., et al.: J. Biol. Chem., 270, 29059 (1995), Bedingfield, J., et al.: Eur. J. Pharmacol., 309, 71 (1996), Jin, W., et al.: Biochemistry, 38, 14294 (1999), Kew, J., et al.: Pharmacol. Ther., 104, 233 ( 2004), Bertaso, F., et al.: J. Neurochem., 99, 288 (2006),<br></p>Formula:C17H20N2O2Color and Shape:NeatMolecular weight:284.35Lifitegrast
CAS:Controlled Product<p>Applications Lifitegrast is used for the treatment of signs and symptons of dry eye diseases. It also Inhibites corneal inflammation that is capable of causing pains, blurred vision and ocular discomfort in sufferer.<br>References Holland, E. J., et al.: Curr. Med. Res. Opin., 32, 1759 (2016); Sun, Y., et al.: J. Ocul. Pharmacol. Ther., 29, 395 (2013);<br></p>Formula:C29H24Cl2N2O7SColor and Shape:White To Off-WhiteMolecular weight:615.481Methyl 2-Oxo-1-pyrrolidineacetate
CAS:<p>Applications Methyl 2-Oxo-1-pyrrolidineacetate is used a reagent in the synthesis of benzoquinolizidine and benzoindolizidine derivatives as anti-amnesic agents. It is also used as a a reagent in the synthesis of (acylamino)acridines as choline uptake enhancers.<br>References Zhao, S., et al.: Bioorg. Med. Chem., 7, 1637 (1999); Chaki, H., et al.: Bioorg. Med. Chem. Lett., 5, 1489 (1995)<br></p>Formula:C7H11NO3Color and Shape:ColourlessMolecular weight:157.17Triazolam N-Oxide
CAS:Controlled Product<p>Applications Triazolam N-Oxide is a derivative of Triazolam (T767380), a sedative.<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976); Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978); Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>Formula:C17H12Cl2N4OColor and Shape:NeatMolecular weight:359.215-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one
CAS:Controlled Product<p>Applications This compound contains a benzimidazolone moiety which has been seen to inhibit p38 MAP kinase , a crucial protein in the activation of biological factors related to psoriasis, rheumatoid arthritis and other inflammatory diseases.<br>References Hammach, A. et al.: Bioorg. Med. Chem. Lett., 16, 6316 (2006);<br></p>Formula:C14H10N2O2Color and Shape:NeatMolecular weight:238.244-(1H-Benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:201.188995361328122-Methyl-5-nitroimidazole
CAS:<p>Impurity Tinidazole EP Impurity A/ Metronidazole EP Impurity A<br>Applications 2-Methyl-5-nitroimidazole (Tinidazole EP Impurity A) is a Floconazole impurity.<br>References Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009), Kumar, L., et al.: Eur. J. Med. Chem., 45, 817 (2010),<br></p>Formula:C4H5N3O2Color and Shape:Light YellowMolecular weight:127.10
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