Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine
CAS:<p>6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is a metabolite that can be found in the urine and blood of humans. It has been shown to have cytotoxic effects on human lymphocytes and erythrocytes. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is used as an impurity standard for HPLC analysis and as a reference compound for pharmacopoeia. This chemical is also used in the synthesis of some drugs. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is not listed in any pharmacopoeia or natural product database.</p>Formula:C9H7Cl2N5Purity:Min. 95%Color and Shape:White PowderMolecular weight:256.09 g/molPantoprazole N-oxide sodium
CAS:<p>Pantoprazole N-oxide sodium is a custom synthesis drug product that is being developed as an impurity standard in the synthesis of Pantoprazole. The compound is also used as a pharmacopoeia analytical standard and a HPLC standard.</p>Formula:C16H15F2N3O5S·NaPurity:Min. 95%Color and Shape:PowderMolecular weight:422.36 g/mol4-Desmethoxy omeprazole sulfide
CAS:<p>4-Desmethoxy omeprazole sulfide is a metabolite of omeprazole, a drug that is used to treat ulcers and gastroesophageal reflux disease. 4-Desmethoxy omeprazole sulfide is not an impurity in the production of omeprazole, but is present as a natural component of omeprazole. This compound has been shown to be an impurity standard for HPLC analysis. The pharmacopoeia defines 4-desmethoxy omeprazole sulfide as an API impurity in drug products. It is also being studied for its potential use in drug development and research and development.</p>Formula:C16H17N3OSPurity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:299.39 g/mol(1R,3S,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl-2'-hydroxy-2',2'-di(thiophen-2''-yl)acetate
CAS:<p>Tanshinone IIA is an enantioselective hydroxamic acid that inhibits matrix metalloproteinase. It is a structural analogue of the hydroxamic acid Tanshinone I and has been shown to inhibit aggrecanase, which is an enzyme that hydrolyzes the glycosaminoglycan aggrecan. It also has anti-cancer effects due to its inhibition of cell proliferation in cancer cells. Tanshinone IIA can be used as a chiral synthon for polymerase chain reactions (PCR) because it contains a stereogenic centre in its structure.</p>Formula:C18H19NO3S2Purity:Min. 95%Color and Shape:PowderMolecular weight:361.48 g/mol2-Mercaptobenzimidazole
CAS:<p>2-Mercaptobenzimidazole is a chemical compound that can be used for the treatment of infectious diseases. It has been shown to have antioxidative properties and inhibit the growth of bacteria. 2-Mercaptobenzimidazole also has an effect on human serum, which may be due to its ability to bind with proteins in serum and form hydrogen bonds. 2-Mercaptobenzimidazole is stable at high temperatures and has been shown as an effective antimicrobial agent against gram positive and gram negative bacteria.</p>Formula:C7H6N2SPurity:Min. 99 Area-%Color and Shape:White/Off-White SolidMolecular weight:150.19 g/mol5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole
CAS:<p>5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole is a natural product. It is an impurity in the drug development process and may be present as an analytical marker for impurities. 5-Methoxy-2-[(3,5-dimethylpyridinium)methyl]sulfinyl]-1Hbenzimidazole is used as a pharmacopoeia standard and can be synthesized on request.</p>Formula:C16H17N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:315.39 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide is an ammonium salt of a sulfoxide with a chloride. It is also known as esomeprazole magnesium. This drug is used in the preparation of pharmaceutical preparations and is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and other conditions. The magnesium salt form is a polymorphic substance that has a crystalline form that occurs in nature, called alpha form, and a synthetic form that occurs in laboratory experiments and has been designated beta form. The alpha form exhibits enantioselectivity when it binds to the enzyme pepsin, which causes the drug to have an antiulcer effect.</p>Formula:C17H19N3O4SPurity:Min. 95%Color and Shape:PowderMolecular weight:361.42 g/molN-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide
CAS:<p>N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide is a pharmaceutical dosage form that is titrated to achieve the desired therapeutic effect. It is used to treat epilepsy and bipolar disorder. Lamotrigine binds to sodium channels in nerve cells and blocks their opening. This prevents the influx of sodium ions that are necessary for neuronal transmission. Lamotrigine has been shown to have an anticonvulsant effect by reducing the frequency of seizures in patients with epilepsy.</p>Formula:C16H9Cl4N5OPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:429.09 g/molRabeprazole Impurity 2
CAS:<p>Rabeprazole Impurity 2 is a research and development impurity standard that is used for qualitative analysis. It can be custom synthesized to meet specific needs, and it can also be used in drug product synthesis. Rabeprazole Impurity 2 is a high purity synthetic compound that has been pharmacopoeia-qualified. It can also be used as a metabolite or analytical standard, and it has been studied for its metabolism studies with HPLC-MS. Rabeprazole Impurity 2 has CAS No. 1807988-36-8.</p>Formula:C18H19N3O4Purity:Min. 95%Molecular weight:341.36 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole
CAS:<p>Omeprazole is a drug that belongs to the class of benzimidazole compounds. It is an inhibitor of gastric acid secretion in the stomach, reducing the production of hydrochloric acid and pepsin. Omeprazole has been shown to have greater chemical stability than other proton pump inhibitors (PPIs), with a higher solubility in water and a longer shelf life. Omeprazole also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Omeprazole also exhibits pharmacokinetic properties that are different from other PPIs. Omeprazole is rapidly absorbed following oral administration and has a high bioavailability, which can be attributed to its hydroxyl group. This hydroxyl group allows for esomeprazole (a prodrug) to be formed by hydrolysis in the gut or liver, increasing omeprazole's absorption and bioavailability.</p>Formula:C17H19N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:329.42 g/molPantoprazole sodium hydrate - Mixture of impurities D and F
CAS:<p>Pantoprazole sodium hydrate is a custom synthesis that is used as a drug product. The CAS number for this compound is 624742-53-6. This compound has the following impurities: D and F. Pantoprazole sodium hydrate has been shown to be metabolized in vitro by human liver microsomes to its metabolites, including the following: (1) pantoprazol acid, (2) 4-hydroxypantoprazol acid, (3) 4-hydroxyisoxazole acid, and (4) 5-(4-hydroxyphenyl)-2H-1,2-benzoxazin-3(4H)-one. The metabolite 4-hydroxypantoprazol acid has been found to be pharmacologically active in animal models of gastric ulceration and healing.</p>Formula:C17H17F2N3O4SPurity:Min. 95%Color and Shape:Off-white to yellow powder.Molecular weight:397.4 g/mol2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole
CAS:<p>Rabeprazole is a proton pump inhibitor that is used to treat acid-related disorders such as gastroesophageal reflux disease and peptic ulcers. Rabeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium ATPase that is found in the parietal cells of the stomach. The main mechanism of action for rabeprazole is competitive inhibition of the proton pump, which leads to decreased gastric acid secretion. Rabeprazole can be administered orally or intravenously, with a half-life of about 2 hours. It has been shown to have an effect on human liver cytochrome P450s, but does not affect the activity of recombinant cytochrome P450 3A4 (CYP3A4). In clinical studies, rabeprazole was shown to have no adverse effects on CYP3A4 activity and may even increase it slightly.</p>Formula:C18H21N3O2SPurity:Min. 95%Color and Shape:White PowderMolecular weight:343.44 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide is a cyclic sulfoxide that has shown to be a potent inhibitor of gastric acid secretion. It is an important intermediate in the synthesis of esomeprazole magnesium, a proton pump inhibitor used to treat gastroesophageal reflux disease and other gastrointestinal disorders. 5-Methoxy-2-[(4-methoxy 3,5 dimethyl 2 pyridinyl) methyl] sulphonyl]-1H benzimidazole N oxide is also known as (RS)-N-[4-(4′ methoxyphenyl)-3,5 dimethylpyrazol -2 - ylmethyl] methanesulfonamide. This compound has been shown to have a polymorphic form with two different</p>Formula:C17H19N3O5SPurity:Min. 95%Color and Shape:PowderMolecular weight:377.42 g/molMethyl 2,2-dithienylglycolate
CAS:<p>Intermediate for tiotropium bromide synthesis</p>Formula:C11H10O3S2Purity:Min. 95%Color and Shape:White PowderMolecular weight:254.33 g/molAlbendazole sulfoxide
CAS:<p>Albendazole sulfoxide is a sulfoxide of albendazole. The molecular docking analysis of the two molecules showed that the sulfoxide group is located in the same position as the hydroxyl group on albendazole. It has been shown that this replacement of hydroxyl with a sulfoxide group increases the solubility and stability of albendazole, which may be due to hydrogen bonding interactions between these groups. Albendazole sulfoxide has been shown to be an effective treatment for infections caused by parasites such as helminths. However, it should not be used in combination with drugs that are metabolized by cytochrome P450 enzymes because it can inhibit their activity.</p>Formula:C12H15N3O3SPurity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:281.33 g/molOmeprazole impurity F and G
CAS:<p>Omeprazole is a proton pump inhibitor that inhibits the H+/K+-ATPase enzyme in gastric parietal cells. Omeprazole impurity F and G are metabolites of omeprazole. Omeprazole impurity F is a metabolite of omeprazole that forms by oxidation of the methylthio group in omeprazole to form a sulfoxide. Omeprazole impurity G is formed by hydrolysis of the methylthio group in omeprazole to form an alcohol. The purity of this product is high and can be custom synthesized based on customer's needs. It is also available as an HPLC standard or as an API impurity for use in metabolism studies.</p>Formula:C16H13N3O2SPurity:Min. 95%Color and Shape:Red PowderMolecular weight:311.36 g/molDi-2-thienylmethanone
CAS:<p>Di-2-thienylmethanone is a pyrazole with an activation energy of about 10.5 kcal/mol. It has been found to be toxic and can cause cell lysis. This molecule has been used in the synthesis of a number of drugs, including thiopental, a barbiturate that is used as an anaesthetic. Di-2-thienylmethanone is also the precursor for the synthesis of fluoroquinolones, which are potent antibacterial agents. The Friedel-Crafts reaction is one way this molecule is synthesized, and it involves the addition of an alkyl halide to an unsaturated double bond. This reaction is named after Charles Friedel and James Crafts who first discovered it in 1877.</p>Formula:C9H6OS2Purity:Min. 95%Color and Shape:White PowderMolecular weight:194.28 g/molN-(2-Phenethyl)benzamide
CAS:<p>N-(2-Phenethyl)benzamide (NPEB) is a molecule that belongs to the group of reactive molecules. It has been shown to be toxic to gram-positive bacteria, such as Staphylococcus aureus and Bacillus subtilis, but not gram-negative bacteria such as Escherichia coli. NPEB also has been shown to have locomotor activity in animals, which may be due to its ability to inhibit the mitochondrial electron transport chain and inhibit ATP production. NPEB's biological properties are well characterized. FTIR spectroscopy showed that this molecule has an amide functional group and is a small molecule with a molecular weight of 176.4 g/mol. This molecule was also found to be able to bind to mitochondria in animals.</p>Formula:C15H15NOPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:225.29 g/mol6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione
CAS:<p>6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione is a chlorinating agent that converts alcohols to alkyl chlorides. It is used for the conversion of diazotizable aromatic compounds to diazo compounds. This compound has been shown to be neuroprotective in animal models and provides protection against glutamate excitotoxicity. 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione also reacts with nitrite ions to form the corresponding nitroso derivatives. These derivatives can cause DNA damage and are mutagenic. 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione has been shown to react with aminoguanidine to produce a chromat</p>Formula:C9H5Cl2N3O2Purity:Min. 95%Color and Shape:PowderMolecular weight:258.06 g/mol(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS:<p>(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a drug used to treat depression. It is an antidepressant drug that inhibits the reuptake of serotonin and norepinephrine in the brain by blocking their transport into the nerve cells. The drug acts as a weak inhibitor of monoamine oxidase (MAO). It also has an effect on bladder function. This compound is synthesized from 1-phenyl-2,5-dihydrothiazole by way of a sequence of reactions that includes the formation of an amine salt via reaction with phosphorus pentoxide and chloroacetic acid followed by conversion to the chloride with thionyl chloride.</p>Formula:C15H15NPurity:Min. 95%Color and Shape:White PowderMolecular weight:209.29 g/molVarenicline
CAS:<p>Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.</p>Formula:C13H13N3Purity:99.76%Color and Shape:SolidMolecular weight:211.261-(5-Bromo-1H-indazol-3-yl)ethanone
CAS:Formula:C9H7BrN2OPurity:97%Color and Shape:No data available.Molecular weight:239.0724-Methyl-oxazole-5-carboxylic acid ethyl ester
CAS:Formula:C7H9NO3Purity:95%Color and Shape:SolidMolecular weight:155.1531-Ethyl-1H-imidazole-5-carbaldehyde hydrochloride
CAS:Formula:C6H9ClN2OPurity:97%Molecular weight:160.64-Bromo-6-(trifluoromethyl)-1H-indazole
CAS:Formula:C8H4BrF3N2Purity:98%Color and Shape:SolidMolecular weight:263.951H-D-His-OH
CAS:<p>M02972 - H-D-His-OH</p>Formula:C6H9N3O2Purity:98%Color and Shape:Solid, CrystallineMolecular weight:155.157(R)-methyl 3-(4-(2-acetyl-1-methyl-1H-imidazol-4-yl)phenyl)-2-((tert-butoxycarbonyl)amino)propanoate
Purity:98%Molecular weight:401.46301271-(4-Chlorophenyl)-1H-imidazole-4-carboxylic acid
CAS:Formula:C10H7ClN2O2Purity:97%Color and Shape:SolidMolecular weight:222.634-Iodoimidazole
CAS:Formula:C3H3IN2Purity:95%Color and Shape:Crystalline PowderMolecular weight:193.9753-Hexadecyl-1-methyl-1H-imidazol-3-ium bromide
CAS:Formula:C20H39BrN2Purity:97%Color and Shape:SolidMolecular weight:387.451-(1H-Indazol-5-yl)ethanone
CAS:Formula:C9H8N2OPurity:98%Color and Shape:SolidMolecular weight:160.1765-Nitro-1H-benzo[d]imidazol-2(3H)-one
CAS:Formula:C7H5N3O3Purity:95%Color and Shape:No data available.Molecular weight:179.135(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(oxazol-5-yl)propanoic acid
CAS:Purity:97%Molecular weight:378.3840027(4-Imidazol-1-yl-phenyl)methanol
CAS:Formula:C10H10N2OPurity:98%Color and Shape:SolidMolecular weight:174.2034-Bromo-2-nitro-1H-imidazole
CAS:Formula:C3H2BrN3O2Purity:97%Color and Shape:SolidMolecular weight:191.9724-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride
CAS:Formula:C5H8Cl2N2Purity:95%Color and Shape:SolidMolecular weight:167.034-(1H-Imidazol-1-yl)benzoic acid
CAS:Formula:C10H8N2O2Purity:97%Color and Shape:White powderMolecular weight:188.186Methyl 1H-indazole-7-carboxylate
CAS:Formula:C9H8N2O2Purity:97%Color and Shape:Solid, Pale yellow solidMolecular weight:176.1754-Bromo-2-methyl-1H-benzimidazole
CAS:Formula:C8H7BrN2Purity:97%Color and Shape:SolidMolecular weight:211.0624-Oxazol-5-yl-benzenesulfonyl chloride
CAS:Formula:C9H6ClNO3SPurity:97%Color and Shape:Off-white solidMolecular weight:243.665-Bromo-7-iodo-1H-indazole
CAS:Formula:C7H4BrIN2Purity:95%Color and Shape:SolidMolecular weight:322.9312-Methyl-2H-indazole-3-carboxylic acid
CAS:Formula:C9H8N2O2Purity:98%Color and Shape:SolidMolecular weight:176.1754-Bromo-1-methyl-1H-benzo[d]imidazole
CAS:Formula:C8H7BrN2Purity:98%Color and Shape:SolidMolecular weight:211.062Boc-D-His(Tos)-OH
CAS:<p>M06184 - BOC-D-HIS(TOS)-OH</p>Formula:C18H23N3O6SPurity:98%Color and Shape:SolidMolecular weight:409.131ETHYL 3-METHYL-2-NITRO-3H-IMIDAZOLE-4-CARBOXYLATE
CAS:Formula:C7H9N3O4Purity:98%Molecular weight:199.1661-(1H-Indazol-1-yl)ethanone
CAS:Formula:C9H8N2OPurity:98%Color and Shape:SolidMolecular weight:160.1761-Methyl-1H-indazole-3-carbaldehyde
CAS:Formula:C9H8N2OPurity:97%Color and Shape:SolidMolecular weight:160.176tert-Butyl 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate
CAS:Purity:97%Molecular weight:358.255-Methyl-6-nitro-1H-indazole
CAS:Formula:C8H7N3O2Purity:98%Color and Shape:SolidMolecular weight:177.0546-Bromo-3-chloro-1H-indazole
CAS:Formula:C7H4BrClN2Purity:98%Color and Shape:Solid, Yellow solidMolecular weight:229.9252-Chloromethylbenzimidazole
CAS:Formula:C8H7ClN2Purity:95%Color and Shape:Tan powderMolecular weight:166.617-Bromo-6-methyl-1H-indazole
CAS:Formula:C8H7BrN2Purity:98%Color and Shape:SolidMolecular weight:209.9796-Bromo-1H-indazole-4-carboxylic acid
CAS:Formula:C8H5BrN2O2Purity:98%Color and Shape:SolidMolecular weight:239.9534-Fluoro-3-iodo-1H-indazole
CAS:Formula:C7H4FIN2Purity:98%Color and Shape:Solid, Yellow solidMolecular weight:261.942,7-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole
CAS:Purity:98%Color and Shape:SolidMolecular weight:272.1600037Ref: 10-F690235
1g183.00€5g492.00€10g970.00€25g1,490.00€2.5g421.00€50mg65.00€100mg75.00€250mg87.00€500mg157.00€2-(1H-Imidazol-1-yl)benzoic acid
CAS:Formula:C10H8N2O2Purity:95%Color and Shape:SolidMolecular weight:188.1862-Oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbaldehyde
CAS:Formula:C8H6N2O2Purity:95%Molecular weight:162.1485-Bromo-1-methyl-1H-imidazole
CAS:Formula:C4H5BrN2Purity:97%Color and Shape:Solid, CrystallineMolecular weight:161.002Ref: 10-F677992
1g569.00€5g1,629.00€10g2,688.00€2.5g1,018.00€50mg113.00€100mg143.00€250mg233.00€500mg353.00€1H-Imidazol-2-amine hydrochloride
CAS:Formula:C3H6ClN3Purity:98%Color and Shape:SolidMolecular weight:119.55(S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid hydrochloride hydrate
CAS:Formula:C6H12ClN3O3Purity:95%Color and Shape:SolidMolecular weight:209.63
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