
Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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(2-Chlorophenyl)diphenylmethane
CAS:Controlled Product<p>Applications (2-Chlorophenyl)diphenylmethane is a triarylmethane with antiproliferative activity. (2-Chlorophenyl)diphenylmethane is an impurity of the antifungal agent Clotrimazole (C587400).<br>References Al-Qawasmeh, R.A. et al.: Bioorg. Med. Chem. Lett., 14, 347 (2004);<br></p>Formula:C19H15ClColor and Shape:NeatMolecular weight:278.782-Amino-5-benzoyl-1-methylbenzimidazole
CAS:Controlled Product<p>Applications Mebendazole (M200500) thermal decomposition product. Mebendazole impurity.<br>References Himmelreich, M., et al.: Aus. J. Pharmaceut. Sci., 6, 123 (1977),<br></p>Formula:C15H13N3OColor and Shape:NeatMolecular weight:251.28Lurasidone Opened Imide (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Lurasidone Opened Imide is an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia.<br>References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008);<br></p>Formula:C28H38N4O3SColor and Shape:NeatMolecular weight:510.694,9-Diisobutyl-1,6-diazecane-2,7-dione
CAS:Controlled Product<p>Applications 4,9-Diisobutyl-1,6-diazecane-2,7-dione is in impurity of rac-Pregabalin (P704800) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C16H30N2O2Color and Shape:NeatMolecular weight:282.42N-Nitroso Aryl Lurasidone
CAS:Controlled ProductFormula:C11H12N4OSColor and Shape:NeatMolecular weight:248.31Benzofuran-6-carboxylic Acid
CAS:Controlled Product<p>Applications Benzofuran-6-carboxylic Acid is a reagent in the development of potent LFA-1/ICAM antagonist SAR 118 as an opthalmic solution for treating dry eyes. Preparation of piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation.<br>References Zhong, M., et al.: ACS Med. Chem., 3, 203 (2012); Fujiwara, N., et al.: Bioorg. Med. Chem., 16, 9804 (2008)<br></p>Formula:C9H6O3Color and Shape:NeatMolecular weight:162.14Prazepam-d5
CAS:Controlled Product<p>Applications Prazepam-d5, is the labeled analogue of Prazepam (P702250), a benzodiazepine derivative drug having anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.<br>References Shader R. I., et al.: Ciba. Found. Symp., (74), 141 (1979); Jacqmin, P., et al.: Neuropsychobiology, 19 (4), 186 (1988);<br></p>Formula:C192H5H12ClN2OColor and Shape:NeatMolecular weight:329.831-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid Sodium Salt
CAS:<p>Applications 1-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid is an impurity of Rabeprazole. It is also a degradation product formed in stressed tablets of Rabeprazole sodium.<br>References Kommanaboyina, B., et al.: Drug Dev. Ind. Pharm., 25, 857 (1999); Carswel, C., et al.: Drugs, 61, 2327 (2001); Garcia, C., et al.: J. Pharm. Biomed. Anal., 46, 88 (2008)<br></p>Formula:C14H10N3NaO3Color and Shape:NeatMolecular weight:291.24(S)-5,6-Dehydro Pregabalin
CAS:Controlled Product<p>Applications (S)-5,6-Dehydro Pregabalin is derived from rac 5,6-Dehydro Pregabalin (D230055), which is an impurity of the anti-convulsant, Pregabalin (P704800).<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>Formula:C8H15NO2Color and Shape:NeatMolecular weight:157.21Isometronidazole-D4
CAS:Controlled Product<p>Applications Isometronidazole-D4 is a labelled analogue of Isometronidazole (I821342). Isometronidazole is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.<br>References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)<br></p>Formula:C6D4H5N3O3Color and Shape:NeatMolecular weight:175.182,5-Dichlorothiophen-3-yl Tioconazole Hydrochloride
CAS:Controlled ProductFormula:C16H12Cl4N2OS·ClHColor and Shape:NeatMolecular weight:458.62Midazolam-d6 (1 mg/mL in Acetonitrile)
CAS:Controlled ProductFormula:C18D6H7ClFN3Color and Shape:Single SolutionMolecular weight:331.802-Chloromethyl-4-methoxy-3-methylpyridine Hydrochloride
CAS:Controlled Product<p>Applications A pyridine derivative used in the preparation of anti-ulcerative agents and other pharmaceutical compounds.<br>References Kuehler, T.C. et al.: J. Med. Chem., 38, 4906 (1995);<br></p>Formula:C8H10ClNO·ClHColor and Shape:NeatMolecular weight:208.08N-Desethyl N-Methyl rac-Rivastigmine
CAS:<p>Impurity Rivastigmin USP Related Compound B<br>Applications N-Desethyl N-Methyl rac-Rivastigmine (Rivastigmin USP Related Compound B) is an impurity in the synthesis of Rivastigmine (R541000) a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C13H20N2O2Color and Shape:Clear ColourlessMolecular weight:236.31Metopimazine-d6
CAS:Controlled Product<p>Applications Labelled Metopimazine (MPZ) is used to prevent emesis during chemotherapies. Antiemetic.<br>References Catz, P., et al.: Int. J. Pharm., 58, 93 (1990), Sato, K., et al.: J. Pharm. Sci., 80, 104 (1991), Herrstedt, J., et al.: Cancer Chemother. Pharmacol., 33, 53 (1996), Sigsgaard, T., et al.: J. Clin. Onc., 19, 2091 (2001),<br></p>Formula:C22H21D6N3O3S2Color and Shape:NeatMolecular weight:451.64Trimebutine-d9 Maleate Salt
CAS:Controlled Product<p>Applications Trimebutine-d9 Maleate Salt, is the labeled analogue of Trimebutine Maleate Salt (T795605), acting as an opioid receptor agonist. Antispasmodic.<br>References Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C22H20D9NO5·C4H4O4Color and Shape:NeatMolecular weight:512.6N-Desethyl N-Methyl Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity B<br>Applications N-Desethyl N-Methyl Rivastigmine (Rivastigmine EP Impurity B) is an impurity of Rivastigmine (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C13H20N2O2Color and Shape:NeatMolecular weight:236.322-Chloroacetamide
CAS:Controlled Product<p>Applications A component of herbicidal mixtures of cellulose biosynthesis inhibitors with VLCFA inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aptula, A., et al.: Chem. Res. Toxicol., 19, 1097 (2006), Chan, K., et al.: J. Appl. Toxicol., 28, 608 (2008),<br></p>Formula:C2H4ClNOColor and Shape:WhiteMolecular weight:93.51N-Nitroso Albendazole (mixtures of regional isomers)
Controlled ProductFormula:C13H16N4O3SColor and Shape:NeatMolecular weight:616.712N-Desmethyl Dextrorphan β-D-O-Glucuronide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A labelled metabolite of Dextromethorphan.<br>References Gonzalez, F., et al.: Nature, 331, 442 (1988), Chen, S., et al.: Clin. Pharmacol. Ther., 60, 522 (1996), Hartter, S., et al.: Ther. Drug Monit., 18, 297 (1996), Garcia-Martin, E., et al.: Clin. Pharmacol. Ther., 71, 196 (2002),<br></p>Formula:C22H29NO7Color and Shape:NeatMolecular weight:419.47

