Benzimidazole and Imidazole Derivatives

<p>Dehydrodeoxy donepezil is an analytical standard that is used in the manufacture of pharmaceuticals. It is a synthetic drug impurity, and its CAS number is 120013-45-8. Dehydrodeoxy donepezil can be found in the API impurity grade of various drugs, including those that are manufactured by Custom synthesis and natural synthesis. The pharmacopoeia states that dehydrodeoxy donepezil has a purity level of 98% or greater. This product can also be found as a metabolite in humans, with its half-life being approximately 40 minutes.</p>

<p>Oxybutynin EP impurity A is a metabolite of oxybutynin, an antispasmodic drug. It has been shown to have immunomodulatory effects in a rat model of adjuvant arthritis. Oxybutynin EP impurity A is the major metabolite of oxybutynin and has been shown to be pharmacologically active in humans.</p>

<p>4-Methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol is a synthetic impurity standard that is used in the synthesis of drug products. This compound is also known as 4-methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol and has a CAS number of 480432-14-2. It is used to verify the purity of drugs and drug products. 4MMPP can be found in pharmacopoeia, drug development, and metabolite studies. This compound is a research and development product for niche markets. 4MMPP can be obtained through custom synthesis or by synthesis.</p>

<p>Lactose conjugate degradation product of pregabalin</p>

<p>1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzi midazole is a high purity analytical standard that is used to calibrate HPLC. It is found as an impurity in the drug product and as a metabolite. 1-[(3-Methyl-4-(2,2,2 -trifluoroethoxy) - 2 - pyridinyl) methyl] - 2 - [[[3 - methyl (4 ( 2 , 2 , 2 - trifluoroethoxy) - 2 pyridinyl) methyl] thio] - 1 H benzimidazole is the IUPAC name for this compound. This chemical has been synthesized</p>

<p>The human red blood cell (RBC) is a non-nucleated cell in the human blood that carries oxygen to the body's cells. The erythrocyte is characterized by its biconcave shape and its lack of organelles. It has a volume of about 80 fL, and a diameter of about 7 micrometers. The RBCs are produced in bone marrow from precursor cells that differentiate into erythroid progenitor cells. This drug binds to the hemoglobin molecules in the red blood cells and alters their shape, causing an increase in their deformability. In addition, this drug decreases the viscosity of the plasma outside of the red blood cell, which increases its extravascular sensitivity. Evaluations have been performed on low doses to evaluate sensitivities within capillaries with microscopy parameters such as magnification and resolution. These evaluations have shown that this drug can be used for quantifying changes in capillary size due to low doses (</p>

<p>Oxybutynin EP impurity B is a metabolite of oxybutynin and is a natural product. It is used as an analytical reference substance, to develop new drugs, and in pharmacopoeia in order to measure the purity of oxybutynin. The compound is synthesized by chemical synthesis and can be used as a standard for HPLC analysis.</p>

<p>Pantoprazole is a proton pump inhibitor that inhibits the gastric acid secretion by blocking the hydrogen/potassium ATPase enzyme in the stomach. Pantoprazole N-oxide, a prodrug of pantoprazole, is converted to pantoprazole after administration and has been shown to be more stable than pantoprazole. It has been shown to have tissue-specific effects, with high concentrations found in gastrointestinal tissues such as the abomasum, ileum, and colon. Pantoprazole N-oxide is also found in plasma samples at low levels. This drug may be useful for ulceration because it prevents heartburn caused by excess stomach acid.</p>

<p>1-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]-2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole is a drug product with analytical applications. It has been shown to have natural and synthetic origins, as well as impurities of its own. It is a custom synthesis and research and development compound that is used for HPLC standardization. The compound has been synthesized for the purpose of drug development and it is intended for niche use.</p>

<p>Lamotrigine is a chemically unrelated compound, which is the active ingredient of a new class of adjuvant drugs for epilepsy. This drug has been found to be effective against seizures in patients with partial seizures and generalized seizures. Lamotrigine is an orally administered suspensoid that can be mixed with water or other liquids to form a suspension. It has been used as a flavouring agent and an adjuvant in pharmaceuticals, including tablets and capsules. The chemical structure of lamotrigine includes two 2,3-dichlorophenyl groups connected by an amino group (guanidinoimino). This structure gives lamotrigine its chemical name: 2-(2,3-dichlorophenyl)-2-(guanidinoimino) acetonitrile.</p>

<p>Impurity 65 is an impurity of Omeprazole, a drug used to treat gastroesophageal reflux disease and peptic ulcer. Impurity 65 is a metabolite of Omeprazole that can be found in the drug product at a concentration up to 0.5%. It has been shown to have anti-inflammatory effects and can be used as a research and development standard for HPLC analysis. Impurity 65 is also used as an impurity standard in the USP pharmacopoeia and other pharmacopoeias around the world.</p>

<p>Lansoprazole impurity H is a metabolite of lansoprazole, a proton pump inhibitor that inhibits the production of stomach acid. Lansoprazole impurity H is used in research and development as an analytical standard to measure lansoprazole concentrations in drug products. It is also used as an impurity standard for pharmacopoeia purposes. Lansoprazole impurity H is not known to be toxic, but it has not been evaluated for carcinogenicity or reproductive toxicity.</p>

<p>Desdifluoromethoxy hydroxy pantoprazole is a synthetic compound that is used as an impurity standard for the drug product Pantoprazole. It has a purity of ≥98% and is stable under ambient conditions. Desdifluoromethoxy hydroxy pantoprazole is not active on its own, but it is a metabolite of pantoprazole. It can be used to study the metabolism of pantoprazole.</p>

<p>2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid is a synthetic compound that is being researched as a potential drug product. It is an impurity standard for HPLC and has been used in the past to develop drugs. The chemical structure of this compound closely resembles that of the natural metabolite 4,5-dimethoxybenzoic acid, which is found in plants such as thyme. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid has shown to inhibit human cytochrome P450 enzymes, which may lead to serious side effects when taken orally.</p>

<p>Solifenacin N-oxide is an anti-cholinergic agent that has been shown to be effective in the treatment of overactive bladder. Solifenacin N-oxide is a prodrug that is hydrolyzed in vivo to solifenacin, its active form. The compound reversibly binds to muscarinic receptors and inhibits the release of acetylcholine. Solifenacin N-oxide has been shown to have low levels of impurities and is highly soluble in water. It was also found to be stable when stored at room temperature for two months. This drug has a high flow rate and moderate retention time, which makes it suitable for reversed-phase liquid chromatography (RPLC). RPLC is a chromatographic technique that separates compounds by size, hydrophobicity, or charge.</p>

<p>2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole is a synthetic, impurity standard that is used in the synthesis of drug products. It has been shown to inhibit the metabolism of drugs and may be used as a marker for drug metabolism. This compound may also be used as a marker in analytical studies to assess the purity of a drug product. 2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole has not been evaluated for safety or efficacy.</p>

<p>N-Desalkyl itraconazole is a triazole antifungal drug that belongs to the group of medicines. It is used in the treatment of systemic mycoses, including blastomycosis and histoplasmosis. N-Desalkyl itraconazole has been shown to inhibit the growth of fungi by interfering with their cell membranes and inhibiting their production of ergosterol. Calibration studies have shown that this drug binds to human liver microsomes and plasma proteins, as well as transporters such as P-glycoprotein. These interactions may influence its pharmacokinetics, which can be determined using a bioanalytical method.</p>

<p>Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.</p>

<p>2,12-Dihydro-1,3-dimethyl-9-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one is a synthetic compound that has not been evaluated in humans. This compound is an impurity standard for the synthesis of an API. The purity of this compound is &gt;98% and it has been shown to be stable under acidic conditions.</p>

<p>(4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2-pyrrolidinone is a synthetic, impurity standard and research and development compound. (4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2pyrrolidinone is used as an analytical reference in the synthesis of other compounds. It is also used in drug development for the treatment of tuberculosis. This product has a high purity level and is pharmacopoeia grade.</p>

<p>Ethyl (S)-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate is an analytical standard used to identify impurities in drug products. It is a metabolite of the drug product and has been shown to be safe for human consumption. The compound is a synthetic chemical that is not found naturally in the environment. CAS No. 180468-42-2</p>

<p>Pantoprazole is a proton pump inhibitor. It is used in the treatment of gastroesophageal reflux disease and other conditions involving excessive stomach acid production. The chemical name for Pantoprazole impurity is (E)-1-(4-chlorophenyl)ethyl-3-[(pyrrolidin-2-yl)oxy]propanediol. This substance is an enantiomer of pantoprazole, which has been determined to be inactive. Pantoprazole impurity can be identified by its melting point, crystallizing habit, and optical rotation. Active carbon filtration can be used to remove this substance from the final product.</p>

<p>Oxybutynin EP Impurity E is a research and development impurity standard that is used in the synthesis of Oxybutynin. It can be synthesized by reacting 2-chloro-4-nitroaniline with potassium tert-butoxide, followed by acetylation with acetic anhydride. The purity and structure of this compound have been verified by gas chromatography, mass spectrometry, and melting point analysis. This impurity standard has a CAS number of 1215677-72-7.<br>Oxybutynin EP Impurity E is used as a drug product for the treatment of overactive bladder, urinary incontinence, and painful bladder syndrome/interstitial cystitis. It also helps to reduce pain due to spinal cord injury or multiple sclerosis. <br>The pharmacopoeia name for this compound is 4-(2-Chloroethyl)-1H-imidazoleacetic acid. It has been found to be</p>

<p>Amino albendazole sulfone is an anthelmintic drug that is used to treat worm infestations in animals. It is the active metabolite of fenbendazole sulfone and has a terminal half-life of 12 hours in humans. Amino albendazole sulfone can be prepared by chromatographic methods, such as liquid chromatography or gas chromatography, and it can be analyzed with a fluorescence detector. This drug has been shown to have a concentration–time curve following administration to rats and results in an increase in the number of worms eliminated from the body.</p>

<p>(R,R)-Solifenacin succinate is a pharmaceutical agent that acts as an antimuscarinic drug. It has been shown to be effective in wastewater treatment, where it was found to reduce the amount of solifenacin and optimised organic chemicals in the water. This drug has also been shown to have antagonist properties against the muscarinic receptor M3.</p>

<p>2-Hydroxy-5-methylphenylbenzenepropanol is an aliphatic phenol that is used as a treatment for benzene poisoning. It is also used as a precursor to other compounds, such as the chlorides and alkylates of 2-hydroxy-5-methylphenylbenzenepropanol. This compound can be synthesized by reacting ethyl benzoylacetate with diisopropylamine in the presence of oxygen and chlorine gas. It is often immobilized using nutrients, l-tartaric acid, or cinnamic acid.</p>

<p>Please enquire for more information about N-Methyl omeprazole (Mixture of isomers with the methylated nitrogens of imidazole) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]-2-[(4-(3-methoxypropoxy)-3-methyl-2-pyridinyl)methylsulfonyl]-1H-benzimidazole (MKC1807) is a synthetic drug product. MKC1807 is an analytical standard in the HPLC assay for the determination of Epiandrosterone sulfate and its metabolites. 1-[4-(3-Methoxypropoxy)-3,5,6,7,8 -pentamethylcyclohexyl]methyl 2-[(4-(3 -methoxypropoxy) 3,5,6,7,8 -pentamethylcyclohexyl)methylsulfonyl]-1H benzimidazole has been shown to be a natural metabolite of Epiandrosterone sulfate. This compound</p>

<p>2-[(4-Chloro-3-methyl-2-pyridinyl)methylthio]-1H-benzimidazole is a drug product. It is an impurity standard for the analytical determination of 2-[(4-chloro-3-methylpyridin)-2yl]thiohydantoin in pharmaceuticals and other chemical products. This compound is also used as a research and development (R&amp;D) metabolite and impurity standard for the synthesis of 4-(4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)pyridine. The CAS number for this compound is 103312-62-5./END&gt;</p>

<p>1-Phenyl-1,2,3,4-tetrahydro-isoquinoline is a synthetic compound which has been used as a lead compound for the development of drugs with dopamine β-hydroxylase inhibitory activity. In vitro studies have shown that 1-phenyl-1,2,3,4-tetrahydro-isoquinoline inhibits human serum dopamine β-hydroxylase and can be used to study the possible role of this enzyme in Parkinson's disease. This drug is racemized in the body and has been found to be effective against Parkinson's disease in rats. It is also an enantiomer that has industrial applications for the production of polyurethane foam insulation coatings.</p>

<p>Solifenacin impurity C is an impurity that is found in the drug product Solifenacin. It has been shown to be a natural metabolite and has been detected in human urine. Solifenacin impurity C is used as an analytical standard for HPLC analyses of solifenacin, and can also be used as a reference material for pharmacopoeia. The purity of this compound is 99%.</p>

<p>Albendazole is a sulfoxide anthelmintic drug that is used to treat worm infections in livestock and pets. Albendazole inhibits the synthesis of the parasitic cell membrane, which disrupts the integrity of the cell and leads to death. The analytical method for measuring albendazole includes extraction with hexane followed by analysis using gas chromatography. In humans, albendazole may be used to treat cancer, especially when it occurs in cavities or fatty tissues. It can also be used as a treatment for certain types of parasitic infections, such as toxoplasmosis, amebiasis, and cysticercosis. Albendazole is absorbed well after oral administration and plasma concentrations are proportional to dosage levels. The most common side effects are nausea and headache.</p>

<p>Pantoprazole sulfone N-oxide is a prodrug that is converted to the active form pantoprazole in the stomach where it inhibits gastric acid secretion. Pantoprazole sulfone N-oxide has been shown to be genotoxic, and can cause polyvinyl chloride to degrade when stored together. Reconstituted solution of this drug should be used within 24 hours after reconstitution, as the chemical stability of this drug decreases rapidly. Validation studies have been conducted on different analytical methods for determining pantoprazole concentrations in reconstituted solutions, and these methods have been harmonized with those published by the United States Pharmacopeia (USP). The pump inhibitor activity of pantoprazole sulfone N-oxide has been demonstrated in dogs, and it is also useful for treating acid reflux disease in humans. Pantoprazole sulfone N-oxide is unstable at high temperatures (&gt;25°C), so should not be refrigerated or</p>

<p>Lactose conjugate degradation product of pregabalin</p>

<p>Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.</p>

<p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>

<p>(S)-4-(2-Methylpropyl)-2-pyrrolidinone is a lactam that has been synthesized in the laboratory. It is an organic solvent that is used in the synthesis of other compounds. The compound has a potential for producing impurities, such as isopropyl and phosphite, during synthesis. (S)-4-(2-Methylpropyl)-2-pyrrolidinone can be synthesized by reacting 2-methylpropionic acid with one equivalent of methylamine. This reaction takes place in an organic solvent and requires kinetic control to avoid side reactions.</p>

<p>(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.</p>

<p>Abeprazan is a potassium-competitive acid blocker targeting acid-related diseases without acid activation.</p>

<p>Metopimazine is a selective and peripherally restricted dopamine D3 and D2 receptors antagonist.</p>

<p>Zolazepam (CI 716), a pyrazole and diazazone derivative, is a benzodiazepine-like veterinary anesthetic.</p>

<p>Isopropyl 2-hydroxy-2-phenylacetate is an inorganic acid that is used as a solvent and as a reagent for sample preparation. It has been shown to be able to dissolve hydroxy methyl cellulose, which is a common component of membranes. In addition, it can be used as an electrospray ionization source and has been shown to have a phase transition temperature of -24 degrees Celsius. Isopropyl 2-hydroxy-2-phenylacetate has also been shown to inhibit the action of cholic acid on kinetics in high-performance liquid chromatography. This chemical compound also contains an ethyl group, which may be due to its derivation from acetone.</p>

Amino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoi

<p>Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.</p>

<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>

<p>(1-Nitroethyl)benzene is a chloride that belongs to the family of muscarinic receptor antagonists. Its amide form is used in medicine as an antiviral agent, and it has been shown to be effective against HIV. (1-Nitroethyl)benzene also binds to the adenosine A3 receptor, which inhibits autoimmune diseases by preventing the proliferation of lymphocytes. The nitro group on this molecule can undergo a number of chemical reactions, including addition with alkylsulfonyl chloride or nitration with nitric acid.</p>

<p>5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is a hydroxide that is obtained by the reflux of 4-hydroxybenzaldehyde with an alkali metal hydroxide. It can be used in the synthesis of benzylated donepezil hydrochloride. 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone condenses with pyridinecarboxaldehyde to produce 1-(4'-pyridylmethylene)indane. This reaction produces a mixture of products, including benzoic acid and the indane derivative.</p>

<p>Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner,</p>

<p>Morinidazole has antibacterial properties for researching anaerobic infections like appendicitis and PID.</p>

<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>