Benzimidazole and Imidazole Derivatives

<p>2-Methoxy-5-methyl-gamma-phenylbenzenepropanol is a synthetic compound that is used as an intermediate in the synthesis of coumarin derivatives. Reaction with sulfonating agents produces sulfones, and reaction with borohydride reagents produces boronates. The synthesis of 2-methoxy-5-methyl-gamma-phenylbenzenepropanol can be accomplished by the reduction of diphenyl ethers with lithium aluminum hydride or borohydride. The reduction can also be carried out using lanthanum oxide and potassium borohydride. The reaction proceeds smoothly at room temperature in nonpolar solvents.<br>2-Methoxy-5-methyl-gamma-phenylbenzenepropanol reacts with chloride to produce the corresponding chlorides, which are useful intermediates for the synthesis of tolterodine tartrate, a drug used to treat urinary inc</p>

<p>Carbamazepine is a drug that has been used to treat epileptic seizures and trigeminal neuralgia. Impurities in the drug are removed by using chromatographic methods, such as high-performance liquid chromatography (HPLC). The rotarod test is an animal model of motor coordination and balance that can be used to assess the effects of drugs on these functions. Carbamazepine impurities may cause depression and have an epileptic effect on animals. Chronic exposure to carbamazepine can lead to drug reactions and gene polymorphisms, which may alter the metabolism of the drug. Analytical methods for determining carbamazepine impurities include HPLC, gas chromatography mass spectrometry (GC-MS), and thin-layer chromatography (TLC).</p>

<p>Scopine-2,2-dithienyl glycolate is a catalyst that belongs to the class of dithienyl glycolates. Scopine-2,2-dithienyl glycolate is used in the pharmaceutical industry as an average catalyst for reactions and can be used to recover dimethylbenzene. The method of detection for scopine-2,2-dithienyl glycolate is based on its ability to absorb light at a wavelength of 360 nm. The reaction solution must be monitored carefully during the synthetic process because it has been shown that it can react with water or air and form hydrogen sulfide gas. If this happens, the reaction solution will become cloudy or turbid. This product is a white crystalline solid that appears as tiny needles and has a melting point of 173 degrees Celsius (340 degrees Fahrenheit).</p>

<p>1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.</p>

<p>The human red blood cell (RBC) is a non-nucleated cell in the human blood that carries oxygen to the body's cells. The erythrocyte is characterized by its biconcave shape and its lack of organelles. It has a volume of about 80 fL, and a diameter of about 7 micrometers. The RBCs are produced in bone marrow from precursor cells that differentiate into erythroid progenitor cells. This drug binds to the hemoglobin molecules in the red blood cells and alters their shape, causing an increase in their deformability. In addition, this drug decreases the viscosity of the plasma outside of the red blood cell, which increases its extravascular sensitivity. Evaluations have been performed on low doses to evaluate sensitivities within capillaries with microscopy parameters such as magnification and resolution. These evaluations have shown that this drug can be used for quantifying changes in capillary size due to low doses (</p>

<p>2-Methoxy-5-methyL-N,N-bis(1-methyLethyl)-gamma-phenyLbenzenepropanamine fumarate (DMXBPC) is an analgesic that has been shown to be a potent inhibitor of the cytosolic phospholipase A2 and is also cytotoxic. DMXBPC has significant cholinergic activity and can inhibit the synthesis of prostaglandins in the prostate gland. DMXBPC binds to the pyridine ring of DOPA and inhibits its conversion to dopamine. The enantiomers of DMXBPC have different effects on inhibition of phospholipase A2, with the (+) form being more potent than the (-) form. This is due to the fact that (+)DMXBPC binds more tightly to the enzyme than (-)DMXBPC does.</p>

<p>7-Hydroxyhyoscyamine is an antibacterial agent that is used in the treatment of bacterial infections. It has been shown to inhibit the growth of a number of bacteria including Staphylococcus aureus, Streptococcus pyogenes, and Escherichia coli. 7-Hydroxyhyoscyamine has been shown to be more potent than 6-hydroxyhyoscyamine (6-OH Hya) for inhibiting protein synthesis in the bacteria. The compound does not have any psychoactive effects, unlike atropine sulfate, which is also an alkaloid found in plants from the Solanaceae family. 7-Hydroxyhyoscyamine can be synthesized by reacting atropine with nitrous acid or hydrochloric acid. This synthetic process leads to n-oxides as impurities, which can be removed by using a reversed phase high performance liquid chromatography (RP HPLC). Validation of this</p>

<p>Donepezil benzyl bromide is a by-product of donepezil hydrochloride, which is an industrially important drug used to treat Alzheimer's disease. It has been shown to be more efficient than its hydrochloride form. Donepezil benzyl bromide is a crystalline substance that is insoluble in water and soluble in organic solvents such as acetone or ethanol. The compound can be purified through recrystallization from an appropriate solvent.</p>

<p>Oxybutynin impurity C is a metabolite of the drug product Oxybutynin (CAS No. 1199574-70-3). It is an analytical standard for HPLC, and a natural impurity in the synthesis of Oxybutynin. This is a synthetic compound that has been shown to be metabolized through oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Oxybutynin impurity C has been used as an analytical reference material for drug development and research and development.</p>

<p>Lactose conjugate degradation product of pregabalin</p>

<p>Oxybutynin EP impurity A is a metabolite of oxybutynin, an antispasmodic drug. It has been shown to have immunomodulatory effects in a rat model of adjuvant arthritis. Oxybutynin EP impurity A is the major metabolite of oxybutynin and has been shown to be pharmacologically active in humans.</p>

<p>Oxybutynin EP impurity B is a metabolite of oxybutynin and is a natural product. It is used as an analytical reference substance, to develop new drugs, and in pharmacopoeia in order to measure the purity of oxybutynin. The compound is synthesized by chemical synthesis and can be used as a standard for HPLC analysis.</p>

<p>2-Methyl-3,4-dimethoxy pyridine hydrochloride is an analytical standard that is used as a reference compound in the pharmaceutical industry to identify impurities in drug products. It also has a niche use as an API impurity and HPLC standard. 2-Methyl-3,4-dimethoxy pyridine hydrochloride is used as an intermediate for the synthesis of other drugs, including benzodiazepines and beta blockers. It is also used in research and development for its high purity. This chemical is natural or synthetic in origin but can be custom synthesized to meet specific requirements. 2-Methyl-3,4-dimethoxy pyridine hydrochloride also has CAS number 1210824-88-6.</p>

<p>Pantoprazole is a proton pump inhibitor that inhibits the gastric acid secretion by blocking the hydrogen/potassium ATPase enzyme in the stomach. Pantoprazole N-oxide, a prodrug of pantoprazole, is converted to pantoprazole after administration and has been shown to be more stable than pantoprazole. It has been shown to have tissue-specific effects, with high concentrations found in gastrointestinal tissues such as the abomasum, ileum, and colon. Pantoprazole N-oxide is also found in plasma samples at low levels. This drug may be useful for ulceration because it prevents heartburn caused by excess stomach acid.</p>

<p>Solifenacin Impurity D is a synthetic impurity of solifenacin. Solifenacin is an anti-cholinergic drug used to treat overactive bladder and urinary incontinence. The purity of this product is 99%. It is soluble in methanol, ethanol, chloroform, and acetone. Solifenacin Impurity D can be used as a reference material for analytical purposes or as an impurity standard in the development of new drugs.</p>

<p>Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.</p>

<p>1-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]-2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole is a drug product with analytical applications. It has been shown to have natural and synthetic origins, as well as impurities of its own. It is a custom synthesis and research and development compound that is used for HPLC standardization. The compound has been synthesized for the purpose of drug development and it is intended for niche use.</p>

<p>(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.</p>

<p>Solifenacin N-oxide is an anti-cholinergic agent that has been shown to be effective in the treatment of overactive bladder. Solifenacin N-oxide is a prodrug that is hydrolyzed in vivo to solifenacin, its active form. The compound reversibly binds to muscarinic receptors and inhibits the release of acetylcholine. Solifenacin N-oxide has been shown to have low levels of impurities and is highly soluble in water. It was also found to be stable when stored at room temperature for two months. This drug has a high flow rate and moderate retention time, which makes it suitable for reversed-phase liquid chromatography (RPLC). RPLC is a chromatographic technique that separates compounds by size, hydrophobicity, or charge.</p>

<p>2-Hydroxy-5-methylphenylbenzenepropanol is an aliphatic phenol that is used as a treatment for benzene poisoning. It is also used as a precursor to other compounds, such as the chlorides and alkylates of 2-hydroxy-5-methylphenylbenzenepropanol. This compound can be synthesized by reacting ethyl benzoylacetate with diisopropylamine in the presence of oxygen and chlorine gas. It is often immobilized using nutrients, l-tartaric acid, or cinnamic acid.</p>

<p>6-Methyl-4-phenyl-3,4-dihydro-1-benzopyran-2-one is an analog of the natural product zearalenone, which can be used as an acid catalyst for the synthesis of various pharmaceuticals. It has a linear range and is structurally similar to a number of other analogs. The chloride ion is involved in the optimization of the extraction parameters and can be replaced by other c1-4 alkyl groups. 6-Methyl-4-phenyl-3,4-dihydro-1 -benzopyran 2 one is typically prepared using a preparative high performance liquid chromatography technique that involves dehydration.</p>

<p>Lamotrigine is a chemically unrelated compound, which is the active ingredient of a new class of adjuvant drugs for epilepsy. This drug has been found to be effective against seizures in patients with partial seizures and generalized seizures. Lamotrigine is an orally administered suspensoid that can be mixed with water or other liquids to form a suspension. It has been used as a flavouring agent and an adjuvant in pharmaceuticals, including tablets and capsules. The chemical structure of lamotrigine includes two 2,3-dichlorophenyl groups connected by an amino group (guanidinoimino). This structure gives lamotrigine its chemical name: 2-(2,3-dichlorophenyl)-2-(guanidinoimino) acetonitrile.</p>

<p>Please enquire for more information about N-Methyl omeprazole (Mixture of isomers with the methylated nitrogens of imidazole) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole is a synthetic, impurity standard that is used in the synthesis of drug products. It has been shown to inhibit the metabolism of drugs and may be used as a marker for drug metabolism. This compound may also be used as a marker in analytical studies to assess the purity of a drug product. 2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole has not been evaluated for safety or efficacy.</p>

<p>Albendazole is an anti-helminthic drug that is structurally classified as a benzimidazole. It has been shown to be effective against a variety of helminths, including roundworms, pinworms, hookworms, and tapeworms. Albendazole impurity F is an analytical standard for the determination of albendazole in pharmaceutical products by HPLC. It also serves as a reference substance to establish the purity of drug products containing albendazole and its metabolites. Albendazole impurity F is not considered to be a metabolite of albendazole because it has been shown to be stable under acidic conditions and can be synthesized from other starting materials.</p>

<p>2,12-Dihydro-1,3-dimethyl-8-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one is a metabolite of the drug 2-[2-(4,5,-dihydroimidazo[1,2a]imidazol -2(3H)-yl)ethoxy]-N-(methylsulfonyl)benzamide. It can be used as an impurity standard for the manufacture of drugs and as a research chemical.</p>

<p>4-Methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol is a synthetic impurity standard that is used in the synthesis of drug products. This compound is also known as 4-methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol and has a CAS number of 480432-14-2. It is used to verify the purity of drugs and drug products. 4MMPP can be found in pharmacopoeia, drug development, and metabolite studies. This compound is a research and development product for niche markets. 4MMPP can be obtained through custom synthesis or by synthesis.</p>

<p>(R,R)-Solifenacin succinate is a pharmaceutical agent that acts as an antimuscarinic drug. It has been shown to be effective in wastewater treatment, where it was found to reduce the amount of solifenacin and optimised organic chemicals in the water. This drug has also been shown to have antagonist properties against the muscarinic receptor M3.</p>

<p>N-Desalkyl itraconazole is a triazole antifungal drug that belongs to the group of medicines. It is used in the treatment of systemic mycoses, including blastomycosis and histoplasmosis. N-Desalkyl itraconazole has been shown to inhibit the growth of fungi by interfering with their cell membranes and inhibiting their production of ergosterol. Calibration studies have shown that this drug binds to human liver microsomes and plasma proteins, as well as transporters such as P-glycoprotein. These interactions may influence its pharmacokinetics, which can be determined using a bioanalytical method.</p>

<p>Dehydrodeoxy donepezil is an analytical standard that is used in the manufacture of pharmaceuticals. It is a synthetic drug impurity, and its CAS number is 120013-45-8. Dehydrodeoxy donepezil can be found in the API impurity grade of various drugs, including those that are manufactured by Custom synthesis and natural synthesis. The pharmacopoeia states that dehydrodeoxy donepezil has a purity level of 98% or greater. This product can also be found as a metabolite in humans, with its half-life being approximately 40 minutes.</p>

<p>Solifenacin impurity C is an impurity that is found in the drug product Solifenacin. It has been shown to be a natural metabolite and has been detected in human urine. Solifenacin impurity C is used as an analytical standard for HPLC analyses of solifenacin, and can also be used as a reference material for pharmacopoeia. The purity of this compound is 99%.</p>

<p>Solifenacin is an anti-cholinergic drug that has been shown to have a potent antagonistic effect on muscarinic receptors. It is used in the treatment of overactive bladder, urinary incontinence, and irritable bowel syndrome. Solifenacin succinate is a metabolite of solifenacin and it has been found to be an antagonist of M3 muscarinic receptors. The presence of solifenacin and its metabolites in wastewater can interfere with treatment processes by inhibiting the removal of other organic chemicals such as tamsulosin hydrochloride. Optimisation studies for solifenacin production have shown that famotidine can be used as a process aid to reduce solifenacin impurities. Famotidine is also an antagonist of M3 muscarinic receptors and can be used to remove solifenacin from wastewater. Analytes detected in wastewater samples include solifenacin, famot</p>

<p>2,12-Dihydro-1,3-dimethyl-9-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one is a synthetic compound that has not been evaluated in humans. This compound is an impurity standard for the synthesis of an API. The purity of this compound is &gt;98% and it has been shown to be stable under acidic conditions.</p>

<p>Impurity 65 is an impurity of Omeprazole, a drug used to treat gastroesophageal reflux disease and peptic ulcer. Impurity 65 is a metabolite of Omeprazole that can be found in the drug product at a concentration up to 0.5%. It has been shown to have anti-inflammatory effects and can be used as a research and development standard for HPLC analysis. Impurity 65 is also used as an impurity standard in the USP pharmacopoeia and other pharmacopoeias around the world.</p>

<p>(S)-4-(2-Methylpropyl)-2-pyrrolidinone is a lactam that has been synthesized in the laboratory. It is an organic solvent that is used in the synthesis of other compounds. The compound has a potential for producing impurities, such as isopropyl and phosphite, during synthesis. (S)-4-(2-Methylpropyl)-2-pyrrolidinone can be synthesized by reacting 2-methylpropionic acid with one equivalent of methylamine. This reaction takes place in an organic solvent and requires kinetic control to avoid side reactions.</p>

<p>Zolazepam (CI 716), a pyrazole and diazazone derivative, is a benzodiazepine-like veterinary anesthetic.</p>

<p>Metopimazine is a selective and peripherally restricted dopamine D3 and D2 receptors antagonist.</p>

<p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>

<p>Abeprazan is a potassium-competitive acid blocker targeting acid-related diseases without acid activation.</p>

<p>Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.</p>

<p>(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.</p>

<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>

<p>5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is a hydroxide that is obtained by the reflux of 4-hydroxybenzaldehyde with an alkali metal hydroxide. It can be used in the synthesis of benzylated donepezil hydrochloride. 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone condenses with pyridinecarboxaldehyde to produce 1-(4'-pyridylmethylene)indane. This reaction produces a mixture of products, including benzoic acid and the indane derivative.</p>

<p>Morinidazole has antibacterial properties for researching anaerobic infections like appendicitis and PID.</p>

<p>Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner,</p>

<p>Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.</p>

<p>(1-Nitroethyl)benzene is a chloride that belongs to the family of muscarinic receptor antagonists. Its amide form is used in medicine as an antiviral agent, and it has been shown to be effective against HIV. (1-Nitroethyl)benzene also binds to the adenosine A3 receptor, which inhibits autoimmune diseases by preventing the proliferation of lymphocytes. The nitro group on this molecule can undergo a number of chemical reactions, including addition with alkylsulfonyl chloride or nitration with nitric acid.</p>

Amino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoi

<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>

<p>Isopropyl 2-hydroxy-2-phenylacetate is an inorganic acid that is used as a solvent and as a reagent for sample preparation. It has been shown to be able to dissolve hydroxy methyl cellulose, which is a common component of membranes. In addition, it can be used as an electrospray ionization source and has been shown to have a phase transition temperature of -24 degrees Celsius. Isopropyl 2-hydroxy-2-phenylacetate has also been shown to inhibit the action of cholic acid on kinetics in high-performance liquid chromatography. This chemical compound also contains an ethyl group, which may be due to its derivation from acetone.</p>