Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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Varenicline dihydrochloride
CAS:Varenicline dihydrochloride is a Selective α4β2 nicotinic acetylcholine receptor partial agonist.Formula:C13H15Cl2N3Purity:99.88% - 99.97%Color and Shape:SolidMolecular weight:284.18Sertaconazole nitrate
CAS:<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Formula:C20H15Cl3N2OS·HNO3Purity:98.66% - 99.65%Color and Shape:SolidMolecular weight:500.78Acotiamide
CAS:Acotiamide, an oral AChE inhibitor (IC50: 1.79μM), improves gastric motility, targeting functional dyspepsia.Formula:C21H30N4O5SColor and Shape:SolidMolecular weight:450.554-Methyl Mebendazole
CAS:Controlled Product<p>Applications Mebendazole (M200500) related compound as anthelmintic agent.<br>References Raeymaekers, A.H.M., et al.: Arzneim.-Forsch., 28, 586 (1978),<br></p>Formula:C17H15N3O3Color and Shape:NeatMolecular weight:309.32Voriconazole-d3
CAS:Controlled Product<p>Applications Labelled Vorizonazole (V760000), used as an antifungal (systemic). An Ergosterol Biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997),<br></p>Formula:C162H3H11F3N5OColor and Shape:White To BeigeMolecular weight:352.33Modafinil-d5 (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Labelled Modafinil (M482502). Modafinil is an α-1-adrenergic agonist. Modafinil is a CNS stimulant; psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease.This is a controlled substance (stimulant).<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999)<br></p>Formula:C152H5H10NO2SColor and Shape:NeatMolecular weight:278.38Methyl Methanesulfonate
CAS:<p>Applications Methyl Methanesulfonate is used as a reagent in the synthesis of 2-Methyllamotrigine (M315350); an impurity of Lamotrigine (L173250) which is an anticonvulsant that inhibits glutamate release, possible through inhibition of sodium, potassium and calcium currents. Also used in treatment of bipolar depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986); Grunze, et al.: Neuropsychobiology, 38, 131 (1998); Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999)<br></p>Formula:C2H6O3SColor and Shape:Colourless LiquidMolecular weight:110.13Lamotrigine N-Acetate
CAS:Controlled Product<p>Applications Lamotrigine N-Acetate is a derivative of the anticonvulsant Lamotrigine (L173250).<br></p>Formula:C11H9Cl2N5OColor and Shape:NeatMolecular weight:298.13(S)-a,a-Diphenyl-3-pyrrolidineacetamide L-Tartrate
CAS:Controlled ProductFormula:C18H20N2O·C4H6O6Color and Shape:NeatMolecular weight:430.451,2,4-Triazole
CAS:<p>Applications 1,2,4-Triazole is present in a large variety of fungicides as C14-demethylase-inhibitors. In addition they are used in synthetic chemical reactions such as the design and preparation of ghrelin receptor ligand antagonists, like JMV 2959.<br>References Moulin, A. et al.: Amino Acids., 44, 301 (2013); Worthington, P. et al.: Bioact. Hetero. Comp. Class., 129, 2012<br></p>Formula:C2H3N3Color and Shape:WhiteMolecular weight:69.07N-Demethyl Trimebutine-d5 Hydrochloride
CAS:Controlled Product<p>Applications The main bioactive labelled metabolite of Trimebutine.<br>References Miura, Y., et al.: Drug Metab. Dispos., 17, 455 (1989), Xue, L., et al.: Eur. J. Pharmacol., 294, 75 (1995), Roman, F., et al.: J. Pharmacol. Exp. Ther., 289, 1391 (1999), Kayser, V., et al.: Life Sci., 66, 433 (2000),<br></p>Formula:C21H22D5NO5·HClColor and Shape:NeatMolecular weight:414.93(S)-4-Nitrophenyl 1-Phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
CAS:Controlled Product<p>Applications (S)-4-Nitrophenyl 1-Phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate is a reactant in the synthesis of solifenacin succinate, an antimuscarinic agent.<br>References Niphade, N.C., et. al.: Monatshefte fuer Chemie, 142, 1181 (2011)<br></p>Formula:C22H18N2O4Color and Shape:NeatMolecular weight:374.39Scopolamine-d3 Hydrobromide Hydrate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),<br></p>Formula:C17H18D3NO4·BrH·xH2OColor and Shape:NeatMolecular weight:387.28Imidocarb
CAS:Controlled Product<p>Applications Imidocarb is a urea derived antiprotozoal agent used in veterinary medicine for the treatment of infection with babesia and other parasites.<br>References Mosqueda, J., et al.: Curr. Med. Chem., 19, 1504 (2012); Wang, Z.J., et al.: J. Agricultural. Food. Chem., 57, 2324 (2009);<br></p>Formula:C19H20N6OColor and Shape:NeatMolecular weight:348.401-CYCLOHEXYL-2-(FURAN-3-YL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXYLIC ACID
CAS:Purity:95.0%Molecular weight:310.3529968261719Oxybutynin N-Oxide 90%
CAS:Controlled Product<p>Applications A metabolite of Oxybutynin.<br>References Hughes, K., et al.: Xenobiotica, 22, 859 (1992), Oki, T., et al.: Biol. Pharm. Bull., 24, 491 (2001), Fetscher, C., et al.: Br. J. Pharmacol., 136, 64 (2002), Zobrist, R., et al.: Pharm. Res., 20, 103 (2003)<br></p>Formula:C22H31NO4Purity:90%Color and Shape:NeatMolecular weight:373.49Miconazole Impurity I
CAS:Controlled Product<p>Impurity Miconazole EP Impurity I<br>Applications Miconazole Impurity I (Miconazole EP Impurity I), is the impurity of Miconazole (M342500), which is an imidazole antifungal agent, that is applied topically to the skin or to mucus membranes for the treatment of fungal infections.<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H15Cl3N2OColor and Shape:NeatMolecular weight:381.683Omeprazole sulfide N-Oxide
CAS:<p>Applications 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole N-Oxide is a metabolite of Omeprazole (O635000), an proton inhibitor used as an antiulcerative agent.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O3SColor and Shape:Off-WhiteMolecular weight:345.421-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
CAS:<p>Impurity Miconazole EP Impurity F<br>Applications 1-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole (Miconazole EP Impurity F) is an impurity of Miconazole (M342505), an antifungal (1,2) agent (topical).<br>References 1. Godefroi, E. et al.: J. Med. Chem. 1969 Sep;12(5):784-91.2. Brugmans, J. et al.: Arch Dermatol. 1970 Oct;102(4):428-32.<br></p>Formula:C18H14Cl4N2OColor and Shape:NeatMolecular weight:416.13cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol
CAS:Controlled ProductFormula:C13H13Cl2N3O3Color and Shape:NeatMolecular weight:330.174-bromo-2-{[(1-methyl-1H-benzimidazol-2-yl)amino]methyl}phenol
CAS:Purity:95.0%Molecular weight:332.200988769531255-Hydroxy Omeprazole Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications The main metabolite of Omeprazole.<br>References Renberg, L., et al.: Drug Metab. Dispos., 17, 69 (1989), Calabresi, L., et al.: Pharmacol. Res., 49, 493 (2004), Yin, O., et al.: J. Clin. Pharmacol., 44, 582 (2004),<br></p>Formula:C17H18N3NaO4SColor and Shape:White To Light YellowMolecular weight:383.401'-Hydroxy Triazolam
CAS:Controlled Product<p>Applications A metabolite of Triazolam (T767380(M)), which is a sedative; a controlled substance (depressant).<br>References Boxenbaum, H., et al.: J. Pharm. Pharm. Sci., 2, 47 (1999), Perloff, M., et al.: J. Pharmacol. Exp. Ther., 292, 618 (2000), Patki, K., et al.: Drug Metab. Dispos., 31, 938 (2003),<br></p>Formula:C17H12Cl2N4OColor and Shape:Light GreenMolecular weight:359.21Oxazepam
CAS:Controlled Product<p>Applications Anxiolytic; muscle relaxant (skeletal); anticonvulsant; ligand for the GABAA receptor benzodiazepine modulatory site. Controlled substance (depressant).<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Sisenwine, et al.: Arzneim. Forsch., 22, 682 (1972), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 3, 441 (1974), Greenblatt, D.J., et al.: Clin. Pharmacokinet., 6, 89 (1981),<br></p>Formula:C15H11ClN2O2Color and Shape:White To Off-WhiteMolecular weight:286.714-(1H-1,2,4-Triazol-1-ylmethyl)benzonitrile
CAS:Controlled ProductFormula:C10H8N4Color and Shape:WhiteMolecular weight:184.20Secnidazole
CAS:Controlled Product<p>Applications Analog of Metronidazole. Antiamebic. Antiprotozoal (Trichomonas).<br>References Cosar, C., et al.: Arzneim.-Forsch., 16, 23 (1966), Videau, D., et al.: Br. J. Vener. Dis., 54, 77 (1978), Symonds, J., et al.: J. Antimicrob. Chemother., 5, 484 (1979),<br></p>Formula:C7H11N3O3Color and Shape:White To Light YellowMolecular weight:185.183,5-Dimethyl-2-pyridinemethanol
CAS:Controlled Product<p>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Formula:C8H11NOColor and Shape:Colourless To BrownMolecular weight:137.179Lamotrigine 5,5-Dimer
Controlled Product<p>Applications Lamotrigine 5,5-Dimer is a dimer impurity of the anticonvulsant Lamotrigine (L173250).<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986), Grunze, et al.: Neuropsychobiology, 38, 131 (1998), Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999),<br></p>Formula:C19H14Cl4N10Color and Shape:Off White SolidMolecular weight:524.19Lansoprazole Sulfide
CAS:Controlled Product<p>Impurity Lansoprazole EP Impurity C; USP Impurity B<br>Applications Lansoprazole Sulfide (Lansoprazole EP Impurity C; USP Impurity B) is a metabolite of Lansoprazole, as gastric pump inhibitor.<br>References Oie, et al.: J. Pharm. Sci., 68, 1203 (1979), Naesdal, J., et al.: Clin. Pharmacol. Ther., 40, 344 (1986), Dube, L., et al.: Biopharm. Drug Dispos., 10, 55 (1989), Barradell, L., et al.: Drugs, 44, 225 (1992),<br></p>Formula:C16H14F3N3OSColor and Shape:WhiteMolecular weight:353.362-Mercaptobenzimidazole
CAS:Controlled Product<p>Impurity Rabeprazole EP Impurity F<br>Applications An antidegradant, protecting rubber from oxidation. An intermediate in the synthesis of Rabeprazole (R070500)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Beheshti, A., et al.: J. Food Sci., 75, C135 (2010), Rohrig, U., et al.: J. Med. Chem., 53, 1172 (2010),<br></p>Formula:C7H6N2SColor and Shape:NeatMolecular weight:150.20N-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl Lansoprazole
CAS:Controlled Product<p>Applications Lansoprazole (L175000) impurity.<br>References Wallmark, B., et al.: J. Gastroenterol., 20, 37 (1985), Barradell, L., et al.: Drugs, 44, 225 (1992), Reddy, K., et al.: Pharmazie, 65, 994 (2006),<br></p>Formula:C25H22F6N4O3SColor and Shape:Beige To Light BrownMolecular weight:572.52rac Desethyl Oxybutynin-d5 Hydrochloride
CAS:Controlled Product<p>Applications A labelled metabolite of the drug Oxybutynin (D289475). Used in the treatment of incontinence.<br>References Hughes, K., et al.: Xenobiotica, 22, 859 (1992), Oki, T., et al.: Biol. Pharm. Bull., 24, 491 (2001), Fetscher, C., et al.: Br. J. Pharmacol., 136, 64 (2002), Zobrist, R., et al.: Pharm. Res., 20, 103 (2003)<br></p>Formula:C20H22D5NO3·HClColor and Shape:White To Off-WhiteMolecular weight:334.47 + (36.46)
![1-CYCLOHEXYL-2-(FURAN-3-YL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXYLIC ACID](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF332898.webp&w=3840&q=75)
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