Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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Methyl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate
Purity:95%Molecular weight:396.19198608398443-Cyclobutyl-1H-indazole
CAS:Purity:>95%Color and Shape:Liquid, No data available.Molecular weight:172.23100280761721-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole
CAS:Purity:98%Molecular weight:284.17001342773445-amino-1-propyl-1H-imidazole-4-carboxamide
CAS:Formula:C7H12N4OPurity:95.0%Color and Shape:SolidMolecular weight:168.2N-Pentanoyl-N-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-L-valine
CAS:Purity:97%Molecular weight:677.84899902343755-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methylbenzoic acid
CAS:Purity:97%Molecular weight:260.268005371093752-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2H-tetrazol-3-ium bromide
CAS:Purity:95%Molecular weight:414.32998657226562-Chloro-5-(2H-tetrazol-5-yl)-4-((thiophen-2-ylmethyl)amino)benzenesulfonamide
CAS:Purity:97.0%Color and Shape:LiquidMolecular weight:370.82998657226562-Butyl-3-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[4.4]non-1-en-4-one
CAS:Purity:97.0%Color and Shape:Solid, White - Almost white powderMolecular weight:428.54000854492192-METHOXY-4-(5-(PYRIDIN-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PHENOL
CAS:Purity:95.0%Molecular weight:317.3479919433594PD 312236, PD 312237 Mixture
CAS:<p>Applications PD 312236 is a pyranoside lactose conjugate degradation product of pregabalin (P704800), a GABA analogue used as an anticonvulsant.<br>References Lovdahl, M.J., et al.: J. Pharma. Biomed. Anal., 28, 917 (2002);<br></p>Formula:C20H35NO11Color and Shape:NeatMolecular weight:465.49Piracetam-d8
CAS:Controlled Product<p>Applications Labelled Piracetam (P500800). Nootropic.<br>References Gobert, J., et al.: J. Pharm. Belg., 27, 281 (1972), Oosterveld, W.J., et al.: Arzneim.-Forsch., 30, 1947 (1980), Chouinard, G., et al.: Psychopharmacol. Bull., 17, 129 (1981),<br></p>Formula:C6D8H2N2O2Color and Shape:NeatMolecular weight:150.21[2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl](2-fluorophenyl)-methanone Dihydrochloride
CAS:Controlled ProductFormula:C18H15ClFN3O• 2(HCl)Color and Shape:White To YellowMolecular weight:343.785,6-Dihydro Midazolam
CAS:Controlled Product<p>Impurity Midazolam EP Impurity A<br>Applications Midazolam (M343000) analog useful as anticonvulsant, muscle relaxant.<br>References Ramig, K., et al.: Tetrahedron Lett., 33, 6279 (1992),<br></p>Formula:C18H15ClFN3Color and Shape:White To Off-WhiteMolecular weight:327.78Lamotrigine-13C3,d3, Major
CAS:Controlled Product<p>Applications An isotopically labelled Lamotrigine (L173250), an anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents. Used in treatment of bipolar depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986), Grunze, et al.: Neuropsychobiology, 38, 131 (1998), Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999),<br></p>Formula:C3C62H3H4Cl2N5Color and Shape:Off-White To Light YellowMolecular weight:262.094,4',4''-Methylidynetrisbenzonitrile (Letrozole Impurity)
CAS:<p>Impurity Letrozole EP Impurity B<br>Applications 4,4',4''-Methylidynetrisbenzonitrile (Letrozole EP Impurity B) is a Letrozole isomeric impurity.<br></p>Formula:C22H13N3Color and Shape:Off-WhiteMolecular weight:319.36N-Ethyl-N-methyl-3-vinylphenyl Carbamate
CAS:Controlled Product<p>Impurity Rivastigmine USP Related Compound F<br>Stability Light Sensitive<br>Applications A related compound of Rivastigmine (R541000), a cholinesterase inhibitor. Rivastigmine USP Related Compound F.<br></p>Formula:C12H15NO2Color and Shape:White SolidMolecular weight:205.252-cyclopropyl-1H-benzimidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:158.203994750976562,3-Dichlorobenzoyl Nitrile
CAS:Controlled Product<p>Applications 2,3-Dichlorobenzoyl Nitrile is an impurity of Lamotrigine (L173250), an anticonvulsant that is used in the treatment of bipolar and depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rao, S.N., et al.: Int. J. Pharma. Pharmaceut. Sci., 4, 133 (2012); Qian, Y., et al.: J. Chem. Sci., 121, 463 (2009);<br></p>Formula:C8H3Cl2NOColor and Shape:NeatMolecular weight:200.022-(2,3-Dichlorphenyl)-2-(guanidinylimino)acetonitrile
CAS:Controlled ProductFormula:C9H7Cl2N5Color and Shape:Light YellowMolecular weight:256.09(S)-Modafinil
CAS:Controlled Product<p>Applications Used for treatment of excessive sleepiness, α1-adrenoceptor agonist.<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999), Purnell, M., et al.: J. Sleep Res., 11, 219 (2002), Dinges, D., et al.: Curr. Med. Res. Opin., 22, 159 (2006)<br></p>Formula:C15H15NO2SColor and Shape:NeatMolecular weight:273.35Letrozole
CAS:<p>Applications A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic.<br>References Bhatnagar, A.S., et al: J. Steroid Biochem. Mol. Biol., 37, 1021 (1990), Pfister, C.U., et al.: J. Pharm. Sci., 83, 520 (1994), Lipton, A., et al.: Cancer, 75, 2132 (1995),<br></p>Formula:C17H11N5Color and Shape:YellowMolecular weight:285.30Triclabendazole Sulfone
CAS:Controlled Product<p>Applications Triclabendazole Sulfone is a metabolite of Triclabendazole (T774175), the only anthelmintic drug, which is active against immature, mature and adult stages of fluke.<br>References Whelan, M., et al.: J. Chromato., 1275, 41 (2013); Barrera, S., et al.; Antimicrob. Agent. Chemother., 56, 3535 (2012);<br></p>Formula:C14H9Cl3N2O3SColor and Shape:Off-WhiteMolecular weight:391.66(4-(3-Methoxypropoxy)-3-methylpyridin-2-yl)methanol Hydrochloride
CAS:Controlled ProductFormula:C11H17NO3·HClColor and Shape:NeatMolecular weight:211.26 + 36.465-Phenylthio-2-aminobenzimidazole
CAS:Controlled Product<p>Applications 5-Phenylthio-2-aminobenzimidazole, is a derivative of Fenbendazole (F246750), an anthelmintic.<br>References Baeder, C., et al.: Experientia, 30, 753 (1974), Van der Put, E., et al.: J. Immunol., 173, 818 (2004), Frasca, D., et al.: J. Immunol., 175, 6633 (2005),<br></p>Formula:C13H11N3SColor and Shape:Light Brown To OrangeMolecular weight:241.31Rufinamide-d2
CAS:Controlled Product<p>Applications Labelled Rufinamide (R701552). Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H6D2F2N4OColor and Shape:White To Light YellowMolecular weight:240.21Benznidazole
CAS:<p>Applications Benznidazole (BNZ) is traditionally used to treat Chagas disease caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, Nifurtimox and Benznidazole, are toxic and present severe side effects.<br>References Abuin, G., et al.: Mol. Biochem. Parasitol ., 35, 229 (1989), Arora, P., et al.: J. Biol. Chem., 270, 6042 (1995), Campos, M., et al.: J. Immunol., 167, 416 (2001), Faundez, M., et al.: Antimicrob. Agents Chemother., 49, 126 (2005),<br></p>Formula:C12H12N4O3Color and Shape:NeatMolecular weight:260.25Efinaconazole
CAS:Controlled Product<p>Applications Efinaconazole is a topical antifungal for onychomycosis. (Synonyms: KP-103)<br>References Sugiura, K., et. al.: Antimicrob. Agents CH., 58, 3837 (2014);<br></p>Formula:C18H22F2N4OColor and Shape:NeatMolecular weight:348.394,4',4''-(1H-Imidazole-2,4,5-triyl)tripyridine
CAS:Purity:97%Color and Shape:SolidMolecular weight:299.33700561523441-Amino Hydantoin-13C3
CAS:<p>Applications 1-Amino Hydantoin Hydrochloride (A611090), a metabolite of Nitrofuran.Environmental contaminants<br>References Tribalat, L., et al.: Anal. Bioanal. Chem., 386, 2168 (2006), Chu, P., et al.: J. Agric. Food Chem., 55, 2129 (2007),<br></p>Formula:C3H5N3O2Color and Shape:White To Light YellowMolecular weight:118.07Hydroxy Metronidazole-d4
CAS:Controlled Product<p>Applications A labelled metabolite of Metronidazole (M338880).<br>References Haller, I., et al.: Antimicrob. Agents Chemother., 22, 165 (1982), Gibson, R., et al.: Clin. Chem., 30, 784 (1984), Kuti, J., et al.: Pharmacotherapy, 25, 935 (2005),<br></p>Formula:C62H4H5N3O4Color and Shape:Off-WhiteMolecular weight:191.18Iminodibenzyl 5-Carbonyl Chloride
CAS:Controlled ProductFormula:C15H12ClNOColor and Shape:NeatMolecular weight:257.71Omeprazole Sulfone
CAS:<p>Impurity USP Omeprazole Related Compound A<br>Applications A metabolite of Omeprazole.<br></p>Formula:C17H19N3O4SColor and Shape:White To Light BrownMolecular weight:361.42Modafinil
CAS:Controlled Product<p>Applications Modafinil is an a-1-adrenergic agonist. Modafinil is a CNS stimulant; psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease.This is a controlled substance (stimulant).<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999), Purnell, M., et al.: J. Sleep Res., 11, 219<br></p>Formula:C15H15NO2SColor and Shape:WhiteMolecular weight:273.35(1R)-(-)-10-Camphorsulfonic Acid
CAS:Controlled Product<p>Impurity Voriconazole EP Impurity E (1R)-Isomer<br>Stability Hygroscopic<br>Applications (1R)-(-)-10-Camphorsulfonic Acid (Voriconazole EP Impurity E (1R)-Isomer) is a chiral derivative of Camphor. Used in the preparation of a chiral recognition polymer that is used in the chiral separation of amino acids. A catalyst in direct animation of α-branched aldehydes (including important biological molecules such as α-Me phenylglycine) with near perfect enantioselectivity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Guo, H. et al.: Polym. Preprints Am. Chem. Soc., 40, 506 (1999); Liu, C. et al.: Org. Lett., 13, 2638 (2011);<br></p>Formula:C10H16O4SColor and Shape:WhiteMolecular weight:232.30Omeprazole
CAS:Controlled Product<p>Applications Omeprazole covalently binds to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O3SColor and Shape:White To Light BrownMolecular weight:345.42Benzhydrol-d5
CAS:Controlled Product<p>Applications Intermediate in the preparation of labelled Modafinil (M482500).<br>References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),<br></p>Formula:C13D5H7OColor and Shape:NeatMolecular weight:189.26(S)-Luliconazole
CAS:Controlled Product<p>Applications (S)-Luliconazole is the (S)--enantiomer of Luliconazole, an azole antifungal drug. Luliconazole was found to interfere with ergosterol biosynthesis in cell-free extracts of Candida albican, while no interference due to (S)-Luliconazole was found.<br>References Uhida, K., et al.: J. Infect. Chemother., 10, 216 (2004); Niwano, ., et al.: Antimicro. Agents Chemother., 42, 967 (1998); Niwanno, Y., et al.: Med. Mycol., 37, 351 (1999)<br></p>Formula:C14H9Cl2N3S2Color and Shape:NeatMolecular weight:354.28Isometronidazole
CAS:Controlled Product<p>Impurity Metronidazole EP Impurity E<br>Applications Isometronidazole (Metronidazole EP Impurity E) is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.<br>References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)<br></p>Formula:C6H9N3O3Color and Shape:NeatMolecular weight:171.156-O-Desmethyl Donepezil-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase.<br>References De Vos, F., et al.: Nuc. Med. Biol., 27, 745 (2000), Okereke, C., et al.: Brit. J. Clin. Pharmacol., 58, 41 (2004),<br></p>Formula:C232H5H22NO3Color and Shape:NeatMolecular weight:370.50
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