Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10382 products of "Benzimidazole and Imidazole Derivatives"
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2-(2-Aminoethyl)-1-methyl-1H-imidazole x 2 HCl
CAS:Formula:C6H13Cl2N3Purity:98.0%Color and Shape:Liquid, No data available.Molecular weight:198.093,4,5-Trimethoxybenzoic Acid
CAS:<p>Applications A metabolite of Trimebutine (T795605(P)), which is an opioid receptor agonist and an antispasmodic.<br>References Dieks, H., et al.: J. Labelled Comp. Radiopharm., 28, 1093 (1990), Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C10H12O5Color and Shape:White To BeigeMolecular weight:212.20Carbamazepine 10,11-Epoxide-d2 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Carbamazepine (C175840).<br>References Bellucci, G., et al.: J. Med. Chem., 30, 768 (1987), Johannessen, S., et al.: Ther. Drug. Monit., 27, 710 (2005), Bialer, M., et al.: Expert Opin. Invest. Drugs, 15, 637 (2006), Williams, J., et al.: J. Clin. Pharmacol., 46, 258 (2006),<br></p>Formula:C15H10D2N2O2Color and Shape:NeatMolecular weight:254.28Efinaconazole-N-oxide
CAS:Controlled Product<p>Applications Efinaconazole-N-oxide is a degradation product and potentially a metabolite of the anti-fungal drug Efinaconazole (E435070).<br>References Sugiura, K., et. al.: Antimicrob. Agents CH., 58, 3837 (2014);<br></p>Formula:C18H22F2N4O2Color and Shape:NeatMolecular weight:364.39(R)-3-Boc-4-(Methoxymethylcarbamoyl)-2,2-dimethyloxazolidine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:288.343994140625Albendazole-d7
CAS:Controlled Product<p>Applications Labelled Albendazole (A511610). An anthelmintic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhao, Y., et al.: Org. Biomol. Chem., 6, 4509 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C12H8D7N3O2SColor and Shape:NeatMolecular weight:272.371,1'-Bis(pyridin-4-ylmethyl)-1H,1'h-2,2'-biimidazole
CAS:Purity:98%Molecular weight:316.36801147460945-Methoxy-2-(4-methoxy-3,5-dimethylpyridin-2-yl)-1H-benzo[d]imidazole
CAS:Controlled Product<p>Applications 5-Methoxy-2-(4-methoxy-3,5-dimethylpyridin-2-yl)-1H-benzo[d]imidazole is an impurity of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C16H17N3O2Color and Shape:NeatMolecular weight:283.334-(2-Methylpropyl)piperidine-2,6-dione
CAS:Formula:C9H15NO2Color and Shape:White SolidMolecular weight:169.22Midazolam Maleate
CAS:Controlled ProductFormula:C18H13ClFN3·C4H4O4Color and Shape:White To Off-WhiteMolecular weight:441.84Lansoprazole Sulfone-d4
CAS:Controlled ProductFormula:C16H10D4F3N3O3SColor and Shape:NeatMolecular weight:389.38Clotrimazole
CAS:<p>Applications Clotrimazole is an antifungal agent.<br>References Podust, L., et al.: J. Biol. Chem., 284, 25211 (2009), Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009), Marciniec, B., et al.: J. Pharm. Biomed. Anal., 50, 675 (2009), McGinnity, D., et al.: Drug Metab. Disposition, 37, 1259 (2009),<br></p>Formula:C22H17ClN2Color and Shape:NeatMolecular weight:344.84(R)-5-Hydroxymethyl Tolterodine
CAS:Controlled Product<p>Applications A metabolite of Tolterodine (T535800), a muscarinic receptor antagonist used in the treatment of urinary incontinence.<br>References Palmer, L., et al.: J. Pharm. Biomed. Anal., 16, 155 (1997), Hills, C., et al.: Drugs, 55, 813 (1998), Wefer, J., et al.: World J. Urol., 19, 312 (2001),<br></p>Formula:C22H31NO2Color and Shape:NeatMolecular weight:341.49Ornidazole
CAS:<p>Applications Anti-infective.<br>References Grunberg, E, et al.: Proc. Soc. Exp. Biol. Med., 133, 490 (1970), Hoffer, M., et al.: J. Med. Chem., 17, 1019 (1974), Schwartz, D.E., et al.: Chemotherapy, 22, 19 (1976),<br></p>Formula:C7H10ClN3O3Color and Shape:Off-WhiteMolecular weight:219.635-(Trifluoromethyl)-2-(4-trifluoromethyl)phenyl-oxazole-4-carboxylic acid
CAS:Formula:C12H5F6NO3Purity:95.0%Molecular weight:325.1665-Hydroxy Omeprazole-d3 Sodium Salt
CAS:Controlled ProductFormula:C17H15D3N3NaO4SColor and Shape:White To Light YellowMolecular weight:386.42cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-4-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate
CAS:<p>Impurity Itraconazole Impurity 16<br>Applications cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-4-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate (Itraconazole Impurity 16) is an impurity in the synthesis of Itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989);<br></p>Formula:C14H15Cl2N3O5SColor and Shape:NeatMolecular weight:408.257Albendazole
CAS:<p>Applications Albendazole is an anthelmintic drug.<br>References Zhao, Y., et al.: Org. Biomol. Chem., 6, 4509 (2008); Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009);<br></p>Formula:C12H15N3O2SColor and Shape:Off WhiteMolecular weight:265.334-Hydroxy Omeprazole Sulfide
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications An intermediate in the preparation of Omeprazole metabolites.<br>References Hoffmann, K., et al.: Drug Metab. Disposition, 14, 341 (1986), Andersson, T., et al.: Brit. J. Clin. Pharmacol., 36, 521 (1993),<br></p>Formula:C16H17N3O2SColor and Shape:NeatMolecular weight:315.394-(1H-Benzoimidazol-2-yl)-1-phenyl-pyrrolidin-2-one
CAS:Purity:95.0%Molecular weight:277.32699584960941-[2-(2-Chlorophenoxy)ethyl]-1H-benzoimidazol-2-ylamine
CAS:Formula:C15H14ClN3OColor and Shape:SolidMolecular weight:287.751-[(furan-2-yl)methyl]-5-phenyl-2,3-dihydro-1H-imidazole-2-thione
Molecular weight:256.320007324218755-fluoro-2-(2-pyrrolidinyl)-1H-benzimidazole dihydrochloride
CAS:Purity:95.0%Molecular weight:278.14999389648445-Nitro-1H-imidazole-1-ethanol
CAS:Controlled Product<p>Applications 5-Nitro-1H-imidazole-1-ethanol (cas# 5006-68-8) is a compound useful in organic synthesis.<br></p>Formula:C5H7N3O3Color and Shape:NeatMolecular weight:157.131,2-Phenylenediamine
CAS:Controlled Product<p>Stability Light and Mositure Sensitive<br>Applications An amino substituted benzene used in the manufacture of dyes. Potential use in sensitive immunosensor for cancer biomarker.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wu, Y. et al.: Anal. Bioanal. Chem., 400, 2141 (2011); Du, D. et al.: Anal. Chem., 82, 2989 (2010);<br></p>Formula:C6H8N2Color and Shape:White To Light YellowMolecular weight:108.144-Methylenepiperidine Hydrochloride
CAS:Controlled Product<p>Applications 4-Methylenepiperidine Hydrochloride is a building block that can be coupled with aryl halides via Suzuki cross-coupling to give benzyl piperidines and related compounds.<br>References Vice, S., et al.: J. Org. Chem., 66, 2487 (2001);<br></p>Formula:C6H11N•(HCl)Color and Shape:NeatMolecular weight:97.163646Tert-butyl4-[5-(4-amino-2-fluoro-phenoxy)-1-methyl-indazol-6-yl]pyrazole-1-carboxylate
CAS:Purity:98%Molecular weight:423.447998046875Hydroxy Itraconazole
CAS:Controlled Product<p>Applications A metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. It is a COVID19-related research product.<br>References Saag, M., et al.: Antimicrob. Agents Chemother., 32, 1 (1988), Haria, M., et al.: Drugs, 51, 585 (1996), Kousoulos, C., et al.: Anal. Bioanal. Chem., 384,199 (2006),<br></p>Formula:C35H40Cl2N8O4Color and Shape:WhiteMolecular weight:707.65Atropine
CAS:<p>Applications Atropine is an nerve agent that occurs naturally in plants of the nightshade family. Atropen is used as a pesticide poisoning and as a muscle relaxant when injected intravenously.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kujak, R., et al.: J. Pharma. Biomed. Anal., 2015<br></p>Formula:C17H23NO3Color and Shape:WhiteMolecular weight:289.374-Methylpentanal (up to 75% hydrated form)
CAS:Controlled Product<p>Applications An intermediate used in the synthesis of Pregabalin (P704800) and related compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Posadas, I., et al.: Br. J. Pharmacol., 142, 331 (2004),<br></p>Formula:C6H12OColor and Shape:Colourless LiquidMolecular weight:100.16N-Desmethyl,-N-nitroso-promethazine
CAS:Controlled ProductFormula:C16H17N3OSColor and Shape:NeatMolecular weight:299.39Triclabendazole Sulfoxide-D3
CAS:Controlled Product<p>Applications Triclabendazole Sulfoxide-D3 is a stable isotopically labelled metabolite of Triclabendazole (T774175), an anthelmintic.<br>References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)<br></p>Formula:C14H6D3Cl3N2O2SColor and Shape:NeatMolecular weight:378.68Triazolam
CAS:Controlled Product<p>Applications Sedative, hypnotic.Controlled substance (depressant).<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976), Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978), Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>Formula:C17H12Cl2N4Color and Shape:WhiteMolecular weight:343.213-Methoxy-temazepam
CAS:Controlled ProductFormula:C17H15ClN2O2Color and Shape:Off-White To Light YellowMolecular weight:314.77Albendazole Sulfoxide
CAS:<p>Impurity Albendazole EP Impurity B<br>Applications Albendazole Sulfoxide (Albendazole EP Impurity B) is a metabolite of Albendazole, an anthelmintic.<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol Lett., 6, 2: 51 (1996)<br></p>Formula:C12H15N3O3SColor and Shape:White To BrownMolecular weight:281.33(R)-Lansoprazole
CAS:<p>Stability Hygroscopic<br>Applications The R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),<br></p>Formula:C16H14F3N3O2SColor and Shape:Off White To Dark BrownMolecular weight:369.364-Nitro-2,3-lutidine N-Oxide
CAS:Controlled Product<p>Applications Nitropyridine oxide derivatives show carcinogenicity and mutagenicity.<br>References Nagao, M., et al.: Cancer Res., 32, 2369 (1972),<br></p>Formula:C7H8N2O3Color and Shape:NeatMolecular weight:168.15
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