Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10373 products of "Benzimidazole and Imidazole Derivatives"
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2-(3-BROMOPHENYL)-1H-BENZOIMIDAZOLE
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:273.132995605468752-Mercaptobenzimidazole
CAS:Controlled Product<p>Impurity Rabeprazole EP Impurity F<br>Applications An antidegradant, protecting rubber from oxidation. An intermediate in the synthesis of Rabeprazole (R070500)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Beheshti, A., et al.: J. Food Sci., 75, C135 (2010), Rohrig, U., et al.: J. Med. Chem., 53, 1172 (2010),<br></p>Formula:C7H6N2SColor and Shape:NeatMolecular weight:150.20Atropine
CAS:<p>Applications Atropine is an nerve agent that occurs naturally in plants of the nightshade family. Atropen is used as a pesticide poisoning and as a muscle relaxant when injected intravenously.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kujak, R., et al.: J. Pharma. Biomed. Anal., 2015<br></p>Formula:C17H23NO3Color and Shape:WhiteMolecular weight:289.37Modafinil Sulfone
CAS:Controlled ProductFormula:C15H15NO3SColor and Shape:NeatMolecular weight:289.34956-Hydroxy-2-mercaptobenzimidazole
CAS:Controlled ProductFormula:C7H6N2OSColor and Shape:NeatMolecular weight:166.201'-Hydroxy Midazolam-β-D-glucuronide
CAS:Controlled Product<p>Applications The major metabolite of Midazolam (M343000(P)). Midazolam is an anesthetic; anticonvulsant; sedative; hypnotic. It is a positive allosteric modulator of the GABAA receptor.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C24H21ClFN3O7Color and Shape:White To Off-WhiteMolecular weight:517.891'-Hydroxy Triazolam
CAS:Controlled Product<p>Applications A metabolite of Triazolam (T767380(M)), which is a sedative; a controlled substance (depressant).<br>References Boxenbaum, H., et al.: J. Pharm. Pharm. Sci., 2, 47 (1999), Perloff, M., et al.: J. Pharmacol. Exp. Ther., 292, 618 (2000), Patki, K., et al.: Drug Metab. Dispos., 31, 938 (2003),<br></p>Formula:C17H12Cl2N4OColor and Shape:Light GreenMolecular weight:359.21rel-(R,R)-Voriconazole
CAS:Controlled Product<p>Applications The (R,R)-enantiomer of Voriconazole. An antifungal (systemic). An ergosterol biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997),<br></p>Formula:C16H14F3N5OColor and Shape:NeatMolecular weight:349.311-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
CAS:<p>Impurity Miconazole EP Impurity F<br>Applications 1-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole (Miconazole EP Impurity F) is an impurity of Miconazole (M342505), an antifungal (1,2) agent (topical).<br>References 1. Godefroi, E. et al.: J. Med. Chem. 1969 Sep;12(5):784-91.2. Brugmans, J. et al.: Arch Dermatol. 1970 Oct;102(4):428-32.<br></p>Formula:C18H14Cl4N2OColor and Shape:NeatMolecular weight:416.133,5-Dimethyl-2-pyridinemethanol
CAS:Controlled Product<p>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Formula:C8H11NOColor and Shape:Colourless To BrownMolecular weight:137.179Oxybutynin N-Oxide 90%
CAS:Controlled Product<p>Applications A metabolite of Oxybutynin.<br>References Hughes, K., et al.: Xenobiotica, 22, 859 (1992), Oki, T., et al.: Biol. Pharm. Bull., 24, 491 (2001), Fetscher, C., et al.: Br. J. Pharmacol., 136, 64 (2002), Zobrist, R., et al.: Pharm. Res., 20, 103 (2003)<br></p>Formula:C22H31NO4Purity:90%Color and Shape:NeatMolecular weight:373.49N-Demethyl Trimebutine-d5 Hydrochloride
CAS:Controlled Product<p>Applications The main bioactive labelled metabolite of Trimebutine.<br>References Miura, Y., et al.: Drug Metab. Dispos., 17, 455 (1989), Xue, L., et al.: Eur. J. Pharmacol., 294, 75 (1995), Roman, F., et al.: J. Pharmacol. Exp. Ther., 289, 1391 (1999), Kayser, V., et al.: Life Sci., 66, 433 (2000),<br></p>Formula:C21H22D5NO5·HClColor and Shape:NeatMolecular weight:414.93Scopolamine-d3 Hydrobromide Hydrate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),<br></p>Formula:C17H18D3NO4·BrH·xH2OColor and Shape:NeatMolecular weight:387.284-(1H-1,2,4-Triazol-1-ylmethyl)benzonitrile
CAS:Controlled ProductFormula:C10H8N4Color and Shape:WhiteMolecular weight:184.20(R)-Pregabalin
CAS:Controlled Product<p>Impurity Pregabalin USP Related Compound A<br>Applications R-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia (less potent than the S-Enantiomer). Pregabalin USP Related Compound A.<br>References Field, M.J. et al.: Br. J. Pharmacol., 132, 1 (2001); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993);<br></p>Formula:C8H17NO2Color and Shape:WhiteMolecular weight:159.23Methyl Methanesulfonate
CAS:<p>Applications Methyl Methanesulfonate is used as a reagent in the synthesis of 2-Methyllamotrigine (M315350); an impurity of Lamotrigine (L173250) which is an anticonvulsant that inhibits glutamate release, possible through inhibition of sodium, potassium and calcium currents. Also used in treatment of bipolar depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986); Grunze, et al.: Neuropsychobiology, 38, 131 (1998); Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999)<br></p>Formula:C2H6O3SColor and Shape:Colourless LiquidMolecular weight:110.134-Methyl Mebendazole
CAS:Controlled Product<p>Applications Mebendazole (M200500) related compound as anthelmintic agent.<br>References Raeymaekers, A.H.M., et al.: Arzneim.-Forsch., 28, 586 (1978),<br></p>Formula:C17H15N3O3Color and Shape:NeatMolecular weight:309.32Iminostilbene
CAS:Controlled Product<p>Impurity Carbamazepine EP Impurity D<br>Applications A metabolite of Carbamazepine (CBZ) (C175840).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lertratanangkoon, K., et al.: Drug Metab. Dispos., 10, 1 (1982), Deleu, D., et al.: Eur. J. Clin. Pharmacol., 57, 243 (2001),<br></p>Formula:C14H11NColor and Shape:Yellow To Dark OrangeMolecular weight:193.24Omeprazole Sulfone N-Oxide
CAS:<p>Impurity Omeprazole EP Impurity I<br>Applications Omeprazole Sulfone N-Oxide (Omeprazole EP Impurity I) is a metabolite of Omeprazole. Impurity I.<br>References Stevens, C.M., et al.: J. Biol. Chem., 75, 182 (1950), Okamoto, S., et al.: Biochem. Biophys. Res. Commun., 101, 440 (1981)<br></p>Formula:C17H19N3O5SColor and Shape:NeatMolecular weight:377.412-((1,3-DIOXOISOINDOLIN-2-YL)METHYL)OXAZOLE-4-CARBOXYLIC ACID
CAS:Purity:95.0%Molecular weight:272.21600341796875Rhodium (5% on Alumina)
CAS:Controlled Product<p>Applications Rhodium is a transition metal catalyst used in a multitude of inorganic synthesis.<br>References Alonso, F. et al.: Chem. Rev., 102, 4009 (2002); Widegren, J. et al.: J. Am. Chem. Soc., 125, 10301 (2003); Blomberg, M. et al.: J. Am. Chem. Soc., 113, 424 (1991);<br></p>Formula:RhColor and Shape:NeatMolecular weight:102.91Rivastigmine N-Oxide (Technical Grade)
CAS:Controlled Product<p>Applications Rivastigmine N-Oxide is an impurity of Rivastigmine (R541000, Tartrate Salt) which is a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993)<br></p>Formula:C14H22N2O3Color and Shape:Light Yellow LiquidMolecular weight:266.345-Desamino 5-Oxo-2,5-dihydro Lamotrigine
CAS:Controlled Product<p>Impurity Lamotrigine EP Impurity A; Lamotrigine USP Related Compound C<br>Applications 5-Desamino 5-Oxo-2,5-dihydro Lamotrigine (Lamotrigine EP Impurity A; Lamotrigine USP Related Compound C) is an impurity of the anticonvulsant Lamotrigine (L173250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Srinivasulu, P. et al.: Chromatographia, 70, 271 (2009);<br></p>Formula:C9H6Cl2N4OColor and Shape:White SolidMolecular weight:257.08(2-Oxopyrrolidin-1-yl)acetic Acid
CAS:<p>Impurity Piracetam Impurity D<br>Applications (2-Oxopyrrolidin-1-yl)acetic acid is a reagent in the preparation of pyrazolopyridines as PDE4B inhibitors.<br>References Mitchell, C. J., et al.: Bioorg. Med. Chem. Lett., 20, 5803 (2010);<br></p>Formula:C6H9NO3Color and Shape:Off-WhiteMolecular weight:143.14Metronidazole
CAS:<p>Applications Used as an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.<br>References Carballo, M., et al.: J. App. Toxicol., 29, 248 (2009), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C6H9N3O3Color and Shape:White To Off-WhiteMolecular weight:171.15Rufinamide
CAS:<p>Applications Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H8F2N4OColor and Shape:White To Off-WhiteMolecular weight:238.19Atropine Sulfate Monohydrate
CAS:Controlled Product<p>Applications Mydriatic; antispasmodic; used in preanesthetic medication.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, R.V., et al.: Br. J. Pharmacol., 15, 170 (1960), Shutt, L.E., et al.: Anaesthesia, 34, 476 (1979), Hinderling, P.H., et al.: J. Pharm. Sci., 74, 703 (1985),<br></p>Formula:C17H23NO3·H2O·H2O4SColor and Shape:White To Light YellowMolecular weight:694.83Fenbendazole Sulfoxide-d3
CAS:Controlled Product<p>Applications A labelled metabolite of Fenbendazole (F246750).<br>References McKellar, Q., et al.: J. Vet. Pharmacol. Ther., 13, 223 (1990), De Ruyck, H., et al.: Food Control., 11, 165 (2000),<br></p>Formula:C152H3H10N3O3SColor and Shape:White To Off-WhiteMolecular weight:318.374-Descarboxamido Rufinamide 4-Methyl Ester
CAS:Controlled Product<p>Applications 4-Descarboxamido Rufinamide 4-Methyl Ester is an impurity in the synthesis of Rufinamide (R701550), an antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C11H9F2N3O2Color and Shape:NeatMolecular weight:253.20Temazepam-13C,d3
CAS:Controlled Product<p>Applications Temazepam-13C,d3 is labelled Temazepam (T017200) which is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Formula:C1513CH10D3ClN2O2Color and Shape:NeatMolecular weight:304.75Imidacloprid-3-hydroxy
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 2-Chloro-5-[[4,5-dihydro-2-(nitroamino)-1H-imidazol-1-yl]methyl]-3-pyridinol is an analog of Imidacloprid (I274990) which is an active ingredient in certain neuro-active insecticides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:C9H10ClN5O3Color and Shape:White To Light BeigeMolecular weight:271.66Clotrimazole
CAS:<p>Applications Clotrimazole is an antifungal agent.<br>References Podust, L., et al.: J. Biol. Chem., 284, 25211 (2009), Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009), Marciniec, B., et al.: J. Pharm. Biomed. Anal., 50, 675 (2009), McGinnity, D., et al.: Drug Metab. Disposition, 37, 1259 (2009),<br></p>Formula:C22H17ClN2Color and Shape:NeatMolecular weight:344.84Tebuconazole
CAS:<p>Applications Tebuconazole is an ergosterol biosynthesis inhibitor present in most pesticide formulations (1,2). Various uptake is observed in plants (3). Drinking water Contaminant Candidate List 3 - CCL 3 as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants. Useful in cannabis testing kits as a component of pesticide mixes (P698235).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Grimalt S. et al.: Anal Bioanal Chem. 2015 Apr;407(11):3083-912. Gent, D. et al.: Plant Dis. 2003 May:87(5) p591-5973. Wang, C. et al.: Pest. Biochem. Physiol. 2007 Jan:87(1) p1-8<br></p>Formula:C16H22ClN3OColor and Shape:White To Light YellowMolecular weight:307.82(R)-Oxybutynin Chloride
CAS:Controlled Product<p>Applications The optically avtice inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.<br>References Park, J.M., et al.: J. Urol., 162, 1110 (1999), Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)<br></p>Formula:C22H31NO3·ClHColor and Shape:NeatMolecular weight:393.95(S)-N-Methyl Pregabalin
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications The major metabolite of Pregabalin.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C9H19NO2Color and Shape:NeatMolecular weight:173.25(S)-Pregabalin
CAS:Controlled Product<p>Applications S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993); Field, M.J., et al.: Pain, 80, 391 (1999);<br></p>Formula:C8H17NO2Color and Shape:Off-WhiteMolecular weight:159.232,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
CAS:Controlled Product<p>Applications Varenicline intermediate.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005),<br></p>Formula:C13H14F3N3OColor and Shape:NeatMolecular weight:285.26Lansoprazole Sulfone
CAS:<p>Impurity Lansoprazole USP Related Compound A<br>Applications A metabolite of Lansoprazole, as gastric pump inhibitor. Lansoprazole USP Related Compound A.<br>References De Morais, S., et al.: Mol. Pharmacol., 46, 594 (1994), Spencer, C., et al.: Drugs, 48, 404 (1994), Pearce, R., et al.: J. Pharmacol. Exp. Ther., 277, 805 (1996), Tassaneeyakul, W., et al.: Br. J. Clin. Pharmacol., 49, 139 (2000),<br></p>Formula:C16H14F3N3O3SColor and Shape:NeatMolecular weight:385.36(S)-Lansoprazole
CAS:Controlled Product<p>Applications The S-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),<br></p>Formula:C16H14F3N3O2SColor and Shape:NeatMolecular weight:369.361-Methyl-12-thioxopyrido[1,2,3,4]imidazole-[1,2-a]benzimidazole-2(12H)-one
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications Lansoprazole (L175000) impurity .<br></p>Formula:C14H9N3OSColor and Shape:Orange To RedMolecular weight:267.312-(PYRIDIN-2-YLMETHYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXYLIC ACID
Purity:90.0%Molecular weight:253.26100158691406Ethyl Chloroacetate
CAS:Controlled ProductFormula:C4H7ClO2Color and Shape:ColourlessMolecular weight:122.55Lansoprazole Sulfide N-Oxide
CAS:<p>Applications Used in the preparation of Lansoprazole and its metabolite and impurities.<br>References Reddy, G. et al.; Synthetic Commun. 38, 3477 (2008)<br></p>Formula:C16H14F3N3O2SColor and Shape:Off White SolidMolecular weight:369.36(S)-Pregabalin Lactam
CAS:<p>Impurity Pregabalin EP impurity A<br>Applications (S)-Pregabalin Lactam is an impurity of (S)-Pregabalin (P704790) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993); Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H15NOColor and Shape:WhiteMolecular weight:141.21Parbendazole
CAS:Controlled Product<p>Applications Parbendazole is a benzimidazole carbamate and a potent inhibitor of microtubule assembly and functions.<br>References Lahon, L.C.. et al.: Ind. J. Pharmacol., 26, 235 (1994); Havercroft, J.C., et al.: J. Cell. Sci., 49, 195 (1981);<br></p>Formula:C13H17N3O2Color and Shape:NeatMolecular weight:247.29Isavuconazole-d4
CAS:Controlled Product<p>Applications Labelled Isavuconazole (I777832). It is a new triazole currently undergoing phase III clinical trials. This compound has shown in vitro activity against a large number of clinical important yeasts and molds including Aspergillus spp., Fusarium spp., Scedosporium spp., Candida spp., the Zygomycetes and Cryptococcus spp.<br>References Ohwada, J., et al.: Bioorg. Med. Chem. Lett., 13, 191 (2003), Guinea, J., et al.: Antimicrob. Agents Chemother., 52, 1396 (2008)<br></p>Formula:C22H13D4F2N5OSColor and Shape:White To YellowMolecular weight:441.49Ravuconazole-d4
CAS:Controlled Product<p>Applications Ergosterol biosynthesis inhibitor. Antifungal.<br>References Fung-Tomc., J.C., et al.: Antimicrob. Agents Chemother., 42, 313 (1988), Tsuruoka, A., et al.: Chem. Pharm. Bull., 46, 623 (1998), Gupta, A.K., et al.: J. Eur. Acad. Dermatol. Venereol., 19, 437 (2005),<br></p>Formula:C22H13D4F2N5OSColor and Shape:NeatMolecular weight:441.49Lormetazepam-13C,d3
CAS:Controlled Product<p>Applications A labelled analog of Lorazepam (L469850). Sedative, hypnotic.Controlled substance (depressant).<br>References Nudelman, A., et al.: J. Pharma. Sci., 63, 1886 (1974), Humpel, M., et al.: Eur. J. Drug Metab. Pharmacokinet., 4, 237 (1979), Girkin, R., et al.: Xenobiotica, 10, 401 (1980),<br></p>Formula:CC15D3H9Cl2N2O2Color and Shape:NeatMolecular weight:339.20
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