Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
At CymitQuimica, we offer high-purity benzimidazoles and imidazoles for research in medicinal chemistry, pharmacology, and biotechnology.
Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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4-(4-Cyanobenzyl)-1,2,4-triazole
CAS:Controlled Product<p>Applications 4-(4-Cyanobenzyl)-1,2,4-triazole is an intermediate in the synthesis of Letrozole (L330100), an oral, non-steroidal, aromatase inhibitor generally used to treat breast cancer as a result of hormone response after surgery.<br>References Bhatnagar, A.S., et al: J. Steroid Biochem. Mol. Biol., 37, 1021 (1990), Pfister, C.U., et al.: J. Pharm. Sci., 83, 520 (1994), Lipton, A., et al.: Cancer, 75, 2132 (1995),<br></p>Formula:C10H8N4Color and Shape:NeatMolecular weight:184.20Iminostilbene N-Carbonyl Chloride
CAS:<p>Impurity Carbamazepine EP Impurity F<br>Stability Hygroscopic, Moisture Sensitive<br>Applications Iminostilbene N-Carbonyl Chloride is an intermediate in the preparation of Carbamazepine (C175840).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bellucci, G., et al.: J. Med. Chem., 30, 768 (1987), Takayama, H., et al.: Bioorg. Med. Chem. Lett., 17, 4729 (2007),<br></p>Formula:C15H10ClNOColor and Shape:NeatMolecular weight:255.70Bis(4-cyanophenyl)methanol
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications A metabolite of Letrozole.<br>References Koyama, E., et al.: Ther. Drug Monit., 15, 224 (1993), Pfister, C., et al.: J. Pharm. Sci., 83, 520 (1994), Vander H.Y., et al.: J. Pharm. Biomed. Anal., 24, 723 (2001), Cohen, M., et al.: Clin. Cancer Res., 8, 665 (2002),<br></p>Formula:C15H10N2OColor and Shape:NeatMolecular weight:234.25Clotrimazole-d5
CAS:Controlled Product<p>Applications Labelled Clotrimazole (C587400). Clotrimazole is an antifungal agent.<br>References Podust, L., et al.: J. Biol. Chem., 284, 25211 (2009), Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009), Marciniec, B., et al.: J. Pharm. Biomed. Anal., 50, 675 (2009), McGinnity, D., et al.: Drug Metab. Disposition, 37, 1259 (2009),<br></p>Formula:C22D5H12ClN2Color and Shape:Off-WhiteMolecular weight:349.872-Hydroxymethyl-1H-benzoimidazole-5-carboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:192.1739959716797Ref: 10-F055245
1gTo inquire2gTo inquire5gTo inquire10gTo inquire25gTo inquire50gTo inquire100mgTo inquire250mgTo inquire500mgTo inquireTriclabendazole Sulfoxide
CAS:<p>Applications Triclabendazole Sulfoxide is a metabolite of Triclabendazole (T774175), the only anthelmintic drug, which is active against immature, mature and adult stages of fluke.<br>References Whelan, M., et al.: J. Chromato., 1275, 41 (2013); Barrera, S., et al.; Antimicrob. Agent. Chemother., 56, 3535 (2012);<br></p>Formula:C14H9Cl3N2O2SColor and Shape:ColourlessMolecular weight:375.66Tinidazole-d5
CAS:Controlled Product<p>Applications Labelled Tinidazole. Antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.<br>References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),<br></p>Formula:C8H8D5N3O4SColor and Shape:NeatMolecular weight:252.32-Nitroaniline
CAS:Controlled Product<p>Impurity Albendazole Impurity 4<br>Applications 2-Nitroaniline, is the main precursor to phenylenediamines, which are converted to benzimidazoles, a family of heterocycles that are key components in pharmaceuticals. Albendazole Impurity 4<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Booth, G.,et al.: Ull. Encyc. Indust. Chem. (2007);<br></p>Formula:C6H6N2O2Color and Shape:NeatMolecular weight:138.12Nimorazole
CAS:Controlled Product<p>Applications Nimorazole is an antimicrobial with activity against anaerobic bacteria and protozoa.<br>References Ratnaparkhi, M.P., et al.: Res. J. Pharma. BIol. Chem. Sci., 3, 303 (2012); Toustrup, K., et al.: Radiotherap. Oncol., 102, 122 (2012);<br></p>Formula:C9H14N4O3Color and Shape:NeatMolecular weight:226.23Dihydro Donepezil(Mixture of Diastereomers)
CAS:Controlled Product<p>Impurity Donepezil Dihydro Impurity<br>Applications A potential metabolite of Donepezil.<br>References Dooley, M., et al.: Drugs Aging, 16, 199 (2000), Gotti, R., et al.: J. Pharm. Biomed. Anal., 24, 863 (2001), Gotti, R., et al.: Anal. Bioanal. Chem., 377, 875 (2003),<br></p>Formula:C24H31NO3Color and Shape:NeatMolecular weight:381.51Albendazole Sulfoxide-d7
CAS:Controlled Product<p>Applications Albendazole Sulfoxide-d7 is the isotope labelled metabolite of Albendazole (A511620), an anthelmintic agent.<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol Lett., 6, 2: 51 (1996)<br></p>Formula:C12H8D7N3O3SColor and Shape:NeatMolecular weight:288.37O-Hydroxyethyl Metronidazole
CAS:Controlled Product<p>Applications O-Hydroxyethyl Metronidazole is the hydroxy ethyl analogue and impurity of the antiprotozoal agent Metronidazole (M338880). O-Hydroxyethyl Metronidazole as well as other 1-substituted-2-methyl-5-nitroimidazoles showed potential antitrichomonal activity.<br>References Kajfez, F. et al.: J. Med. Chem., 11, 167 (1968);<br></p>Formula:C8H13N3O4Color and Shape:Yellowish SolidMolecular weight:215.212-Methyllamotrigine Methanesulfonate
CAS:<p>Applications 2-Methyl-Lamotrigine is an impurity of Lamotrigine (L173250), an anticonvulsant which inhibits glutamate release, possible through inhibition of sodium, potassium and calcium currents. Used in treatment of bipolar depression.<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986), Grunze, et al.: Neuropsychobiology, 38, 131 (1998), Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999),<br></p>Formula:C10H9Cl2N5·CH4O3SColor and Shape:Off White SolidMolecular weight:366.22Diethyl Rivastigmine
CAS:Controlled Product<p>Applications An impurity in Rivastigmine (R541000), a cholinesterase inhibitor.<br>References Tse, F., et al.: Pharm. Res., 15, 1614 (1998), Melchiorre, C., et al.: J. Med. Chem., 47, 5945 (2004), Srinivasu, M., et al.: J. Pharm. Biomed. Anal., 37, 57 (2005),<br></p>Formula:C15H24N2O2Color and Shape:NeatMolecular weight:264.3633Albendazole Sulfone-d7
CAS:Controlled Product<p>Applications Albendazole Sulfone-d7 is the isotope labelled metabolite of Albendazole (A511610), an anthelmintic agent.<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol. Lett., 6, 2: 51 (1996)<br></p>Formula:C12H8D7N3O4SColor and Shape:NeatMolecular weight:304.37Varenicline N-Glucoside
CAS:Controlled Product<p>Applications A metabolite of Varenicline. Metabolite M7.<br>References Dow, J., et al.: Drug Metab. Dispos., 22, 738 (1994), Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005),<br></p>Formula:C19H23N3O5Color and Shape:NeatMolecular weight:373.402-Phenyl-1H-benzo[d]imidazole-5-sulfonic acid
CAS:Purity:95.0%Color and Shape:Solid, White - Pale yellow powderMolecular weight:274.29000854492193-Methoxybenzene-1,2-diamine
CAS:<p>Applications 3-Methoxybenzene-1,2-Diamine (cas# 37466-89-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C7H10N2OColor and Shape:BrownMolecular weight:138.172-Cyclohexyl-2-hydroxy-phenylacetic Acid
CAS:Controlled Product<p>Impurity Oxybutynin USP Related Compound A<br>Applications An intermediate in the synthesis of oxybutynin (O868525). Oxybutynin USP Related Compound A.<br></p>Formula:C14H18O3Color and Shape:WhiteMolecular weight:234.2910,11-Dihydro-10-hydroxy Carbamazepine-D4 (Major)
CAS:Controlled ProductFormula:C152H4H10N2O2Color and Shape:BrownMolecular weight:258.31a-Descyclohexyl-a-phenyl Oxybutynin
CAS:Controlled Product<p>Impurity Oxybutynin EP Impurity B<br>Applications α-Descyclohexyl-α-phenyl Oxybutynin (Oxybutynin EP Impurity B) is an Oxybutynin impurity; 4-(dialkylamino)-2-butynyl benzilates as parasympatholytic substances.<br>References Dahlbom, R., et al.: Acta Chem. Scand., 17, 2354 (1963),<br></p>Formula:C22H25NO3Color and Shape:NeatMolecular weight:351.443-Bromo Zolpidem
Controlled ProductFormula:C19H20BrN3OColor and Shape:White To Off-WhiteMolecular weight:386.292-(((6-(Difluoromethoxy)-1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-3,4-dimethoxypyridine 1-oxide
CAS:Purity:95.00%Molecular weight:399.36999511718752,3-Diphenyl-5-(thiophen-2-yl)-2H-tetrazol-3-ium chloride
CAS:Purity:98%Molecular weight:340.8299865722656Miconazole Impurity H
CAS:Controlled Product<p>Impurity Miconazole EP Impurity H<br>Applications Miconazole Impurity H (Miconazole EP Impurity H), is the impurity of Miconazole (M342500), which is an imidazole antifungal agent, that is applied topically to the skin or to mucus membranes for the treatment of fungal infections.<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H16Cl2N2OColor and Shape:NeatMolecular weight:347.246-(1-METHYL-1H-PYRAZOL-4-YL)-3-((2-METHYL-2H-INDAZOL-5-YL)THIO)-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE
CAS:Purity:95.0%Molecular weight:362.4200134277344Ilaprazole
CAS:Controlled Product<p>Applications Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.<br>References Cao, S., et al.: Acta Pharmacol. Sin., 33, 1095 (2012); Wang, L., et al.: J. Clin. Gastroenterol., 45, 322 (2011)<br></p>Formula:C19H18N4O2SColor and Shape:NeatMolecular weight:366.445-Methyl-2-phenoxypyridine
CAS:Controlled ProductFormula:C12H11NOColor and Shape:NeatMolecular weight:185.23N-Ethyl-N-(4-picolyl)atropamide (>85%)
CAS:<p>Stability Light Sensitive<br>Applications N-Ethyl-N-(4-picolyl)atropamide is a major impurity of Tropicamide (T892650), a medication used to dilate the pupil.<br>References Stefanowicz, Zdzislawa, et al.: J. of Pharma. and Biomed. Analy., 49(2), 214-220 (2009)<br></p>Formula:C17H18N2OPurity:>85%Color and Shape:NeatMolecular weight:266.341-(3-chloro-2-methylphenyl)-5-phenyl-2,3-dihydro-1H-imidazole-2-thione
CAS:Purity:98%Molecular weight:300.79998779296875Tofenacin Hydrochloride Salt
CAS:Controlled Product<p>Applications A metabolite of Orphenadrine (O695300). An antidepressant prodrug. Ondansetron USP Related Compound C.<br>References Watkins, P., et al.: J. Biol. Chem., 261, 6264 (1986), McNeil, C., et al.: Biochem. Pharmacol., 51, 15 (1996), Hiessbock, R., et al.: J. Med. Chem., 42, 1921 (1999),<br></p>Formula:C17H21NO·ClHColor and Shape:NeatMolecular weight:291.82N-[3-(1H-imidazol-1-yl)propyl]-4,5-dimethyl-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:286.3999938964844((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone
CAS:Controlled Product<p>Impurity Solifenacin EP Impurity D<br>Applications ((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Formula:C31H28N2OColor and Shape:NeatMolecular weight:444.57N-Isopropylnortropine Methobromide (Impurity)
CAS:Controlled Product<p>Impurity Ipratropium EP Impurity A<br>Applications N-Isopropylnortropine Methobromide (Ipratropium EP Impurity A) is an impurity of Ipratropium (Bromide Monohydrate: I740500), an Atropine (A794625)-like bronchodilator that acts via an anticholinergic pathway, and is used to treat patients with chronic bronchitis, cardiac obstructive pulmonary disease (COPD) and asthma.<br>References Baigelman, W. & Chodosh, S.: CHEST J., 71, 324 (1977); Groggins, R., et al.: Arch. Dis. Child., 56, 342 (1981); Sichletidis, L., et al.: Int. J. Clin. Prac., 53, 185 (1998)<br></p>Formula:C11H22NO·BrColor and Shape:White To Off-WhiteMolecular weight:264.20(S)-Pregabalin Lactam
CAS:<p>Impurity Pregabalin EP impurity A<br>Applications (S)-Pregabalin Lactam is an impurity of (S)-Pregabalin (P704790) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993); Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H15NOColor and Shape:WhiteMolecular weight:141.213-Cyano-5-methylhexanoic Acid
CAS:Controlled Product<p>Applications 3-Cyano-5-methylhexanoic Acid, a derivative of rac-Pregabalin (P704800), a GABA analogue used as an anticonvulsant.<br>References Taylor, C. at al.: Epilepsy Res., 14, 11 (1993); Field, M. et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H13NO2Color and Shape:NeatMolecular weight:155.198-Chloro-1-methyl-6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepine
CAS:Controlled Product<p>Impurity Midazolam EP Impurity G<br>Applications 8-Chloro-1-methyl-6-phenyl-4H-Imidazo[1,5-a][1,4]benzodiazepine is an impurity of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000);<br></p>Formula:C18H14ClN3Color and Shape:Brown SolidMolecular weight:307.78Midazolam
CAS:Controlled Product<p>Applications Anesthetic; anticonvulsant; sedative; hypnotic. Positive allosteric modulator of the GABAA receptor. Neuroprotective & Neuroresearch products.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3Color and Shape:White To Off-WhiteMolecular weight:325.771'-Hydroxy Midazolam-β-D-glucuronide-d5
CAS:Controlled ProductFormula:C24H16D5ClFN3O7Color and Shape:White To Off-WhiteMolecular weight:522.92rac Dihydro Mebendazole
CAS:<p>Applications The reduced metabolite of Mebendazole (M200500).<br>References Facino, R., et al.: Biol. Mass Spectrom, 21, 195 (1992), Iosifidou, E., et al.: Drug Metab. Dispos., 25, 317 (1997), De Ruyck, H., et al.: J. Agric. Food Chem., 49, 610 ( 2001),<br></p>Formula:C16H15N3O3Color and Shape:Light YellowMolecular weight:297.314-Hydroxy Omeprazole Sulfide
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications An intermediate in the preparation of Omeprazole metabolites.<br>References Hoffmann, K., et al.: Drug Metab. Disposition, 14, 341 (1986), Andersson, T., et al.: Brit. J. Clin. Pharmacol., 36, 521 (1993),<br></p>Formula:C16H17N3O2SColor and Shape:NeatMolecular weight:315.394-Methylpentanal (up to 75% hydrated form)
CAS:Controlled Product<p>Applications An intermediate used in the synthesis of Pregabalin (P704800) and related compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Posadas, I., et al.: Br. J. Pharmacol., 142, 331 (2004),<br></p>Formula:C6H12OColor and Shape:Colourless LiquidMolecular weight:100.16Apoatropine Hydrochloride
CAS:<p>Applications Apoatropine is an alkaloid derivative with the potential to be an antibacterial.<br>References Cherkaoui, S. et al.: Electrophor., 19, 2900 (1998); Marrero-Ponce, Y. et al.: Bioorg. Med. Chem., 13, 2881 (2005);<br></p>Formula:C17H21NO2·ClHColor and Shape:White To Off-WhiteMolecular weight:307.823a,4,5,6-Tetrahydro Midazolam
CAS:Controlled Product<p>Applications 3a,4,5,6-Tetrahydro Midazolam is an impurity of Midazolam (M343000), a drug used for the treatment of acute seizures and is also known to exhibit activities as an anticonvulsant, sedative, and hypnotic.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000); Sati, B., et al.: Acta Pharm., 63, 385 (2013);<br></p>Formula:C18H17ClFN3Color and Shape:NeatMolecular weight:329.80
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