Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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4-(1h-1,3-Benzodiazol-1-yl)benzoic acid hydrochloride
CAS:Purity:95%Molecular weight:274.700012207031252-Mercapto-4,5,6,7-d4-benzimidazole
CAS:Controlled ProductFormula:C72H4H2N2SColor and Shape:NeatMolecular weight:154.23N-(2-Hydroxyethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide
CAS:<p>Applications N-(2-Hydroxyethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide is a photolysis product of Metronidazole (M338880), an antibiotic.<br>References Moore, Douglas E., et al.: Radiation Phy. and Chem., 36(4), 547-50 (1990)<br></p>Formula:C6H9N3O3Color and Shape:NeatMolecular weight:171.154Sodium (S)-6-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
CAS:Purity:97%Molecular weight:405.3500061035156Oxazepam-d5
CAS:Controlled Product<p>Applications Labelled Oxazepam. Anxiolytic; muscle relaxant (skeletal); anticonvulsant; ligand for the GABAA receptor benzodiazepinemodulatory site.Controlled substance (depressant).<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Sisenwine, et al.: Arzneim. Forsch., 22, 682 (1972), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 3, 441 (1974), Greenblatt, D.J., et al.: Clin. Pharmacokinet., 6, 89 (1981),<br></p>Formula:C152H5H6ClN2O2Color and Shape:Off-WhiteMolecular weight:291.74Tert-Butyl 6-(benzyloxy)-4-fluoro-1H-indazole-1-carboxylate
CAS:Purity:95.0%Molecular weight:342.36999511718752-Methyl-5-nitroimidazole
CAS:<p>Impurity Tinidazole EP Impurity A/ Metronidazole EP Impurity A<br>Applications 2-Methyl-5-nitroimidazole (Tinidazole EP Impurity A) is a Floconazole impurity.<br>References Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009), Kumar, L., et al.: Eur. J. Med. Chem., 45, 817 (2010),<br></p>Formula:C4H5N3O2Color and Shape:Light YellowMolecular weight:127.10Triazolam N-Oxide
CAS:Controlled Product<p>Applications Triazolam N-Oxide is a derivative of Triazolam (T767380), a sedative.<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976); Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978); Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>Formula:C17H12Cl2N4OColor and Shape:NeatMolecular weight:359.2110-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide
CAS:Controlled Product<p>Applications 10-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide is an intermediate in the synthesis of Oxacarbazepine (O869250) related compounds.<br></p>Formula:C17H14N2O3Color and Shape:NeatMolecular weight:294.301,3-Di(1H-imidazol-1-yl)benzene
CAS:Purity:97%Color and Shape:SolidMolecular weight:210.24000549316406Hydroxy Metronidazole
CAS:<p>Applications A metabolite of Metronidazole (M338880).<br>References Haller, I., et al.: Antimicrob. Agents Chemother., 22, 165 (1982), Gibson, R., et al.: Clin. Chem., 30, 784 (1984), Kuti, J., et al.: Pharmacotherapy, 25, 935 (2005),<br></p>Formula:C6H9N3O4Color and Shape:WhiteMolecular weight:187.151-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester (>90%)
<p>Impurity Fesoterodine Impurity 6;<br>Applications 1-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester is derived from (R)-Fesoterodine Fumarate (F321300), which is a muscarinic receptor antagonist for the treatment of Lower Urininary Tract Symptoms (LUTS). It is very similar to Tolterodine (T535800).<br>References Rogers, D., et al.: Pharmacotherapy, 20, 1092 (2000), Praharaj, S., et al.: J. Psychopharmacology, 19, 426 (2005),<br></p>Formula:C26H35NO5Purity:>90%Color and Shape:NeatMolecular weight:441.561-(2-(Pyrrolidin-1-yl)ethyl)-1H-benzo[d]imidazol-2-amine
CAS:Purity:98%Molecular weight:230.31500244140625rel-(1R,3S,5S)-8-Methyl-8-azabicyclo[3,2,1]oct-6-en-yl-2-hydroxy-2,2-dithiophen-2-yl acetate
CAS:Controlled Product<p>Impurity Tiotropium EP impurity D<br>Applications (1R,3S,5S)-8-Methyl-8-azabicyclo[3,2,1]oct-6-en-yl-2-hydroxy-2,2-dithiophen-2-ylacetate is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.<br>References Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);<br></p>Formula:C18H19NO3S2Color and Shape:NeatMolecular weight:361.48N-Methyl Omeprazole (Mixture of isomers with the methylated nitrogens of imidazole)
CAS:Controlled Product<p>Applications Omeprazole (O635000) impurity.<br>References Allenmark, S., et al.: Anal. Biochem., 136, 293 (1984), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997),<br></p>Formula:C18H21N3O3SColor and Shape:Off White SolidMolecular weight:359.445-Hydroxy Lansoprazole Potassium Salt
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Lansoprazole, as gastric pump inhibitor.<br>References Uno, T., et al.: J. Clin. Pharmacol., 45, 690 (2005), Saito, M., et al.: Brit. J. Clin. Pharmacol., 59, 302 (2005),<br></p>Formula:C16H13F3N3O3S·KColor and Shape:NeatMolecular weight:423.452,3,5-Trimethylpyridine N-Oxide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Formula:C8H11NOColor and Shape:Off-White To Light BrownMolecular weight:137.18Desnitro-imidacloprid Hydrochloride
CAS:Controlled ProductFormula:C9H11ClN4·ClHColor and Shape:Light Orange GreyMolecular weight:247.122,3-Diphenyl-5-(thiophen-2-yl)-2H-tetrazol-3-ium chloride
CAS:Purity:98%Molecular weight:340.82998657226562,3-Bis(4-methoxyphenyl)-5-phenyl-2H-tetrazol-3-ium chloride
CAS:Purity:98%Molecular weight:394.8599853515625Scopine Di(2-thienylglycolate)
CAS:<p>Impurity Tiotropium EP Impurity B<br>Applications Scopine Di(2-thienylglycolate) (Tiotropium EP Impurity B) is a precursor to Tiotropium Bromide.<br>References Buchwald, P., et al.: Pharmazie., 55, S210 (2000),<br></p>Formula:C18H19NO4S2Color and Shape:NeatMolecular weight:377.48Metconazole
CAS:<p>Applications Metconazole is a conazole based fungicide used for the control of black sigatoka disease on bananas. Metconazole acts primarily as an inhibitor of ergosterol biosynthesis which interferes with the synthesis of fungal cell membranes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cools, H.J., et al.: Pest. Manage. Sci., 68, 1034 (2012); Nam, M.H., et al.: Res. Plant. Disease., 17, 295 (2011);<br></p>Formula:C17H22ClN3OColor and Shape:White To Off-WhiteMolecular weight:319.83N-Nitroso Dextromethorphan
CAS:Controlled Product<p>Applications N-Nitroso Dextromethorphan is an impurity of Dextromethorphan (D299445). Dextromethorphan is an antitussive compound showing analgesic properties. Used in cough medication formulations.<br>References Church J. et al.: Can J Physiol Pharmacol., 67, 561 (1989); Carliss, R. et al.: Neurotoxicology., 28, 813 (2007);<br></p>Formula:C17H22N2O2Color and Shape:Light YellowMolecular weight:286.369N-Nitroso Imidapril
Controlled ProductFormula:C20H26N4O7Color and Shape:Off-WhiteMolecular weight:434.4435-(4-chlorophenyl)-1-(2-methoxyphenyl)-2,3-dihydro-1H-imidazole-2-thione
Molecular weight:316.79998779296875Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
CAS:Purity:97%Molecular weight:411.46099853515625N-Desalkyl Itraconazole
CAS:Controlled Product<p>Applications N-Desalkyl Itraconazole is a derivative of itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C31H30Cl2N8O4Color and Shape:NeatMolecular weight:649.534-Ethyl-5-fluoropyrimidine
CAS:<p>Impurity Voriconazole EP Impurity C<br>Stability Volatile<br>Applications 4-Ethyl-5-fluoropyrimidine (Voriconazole EP Impurity C) is a Voriconazole (V760000) impurity.<br>References Miletic, T. et al.: Carb. polym., 98, 122 (2013); Rieke, R., et al.: Science, 246, 1260 (1989), Dickinson, R., et al.: Bioorg. Med. Chem. Lett., 6, 2031 (1996),<br></p>Formula:C6H7FN2Color and Shape:NeatMolecular weight:126.135-(4'-(BROMOMETHYL)-[1,1'-BIPHENYL]-2-YL)-2-TRITYL-2H-TETRAZOLE
CAS:Purity:95%Molecular weight:557.4949951171875α,α,2,6-Tetrachloro-toluene
CAS:Controlled Product<p>Impurity Isoconazole Impurity 9<br>Applications α,α,2,6-Tetrachloro-toluene (Isoconazole Impurity 9) is an impurity of Isoconazole (I798250), an antibacterial and antifungal agent used to treat vaginitis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Asikoglu, M. et al.: J. Pharm. Pharmacol. 47, 717 (1995); Marrero-Ponce, Y. et al.: Bioorg. Med. Chem. 13, 2881 (2005)<br></p>Formula:C7H4Cl4Color and Shape:Light YellowMolecular weight:229.92Albendazole Sulfoxide-d7
CAS:Controlled Product<p>Applications Albendazole Sulfoxide-d7 is the isotope labelled metabolite of Albendazole (A511620), an anthelmintic agent.<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol Lett., 6, 2: 51 (1996)<br></p>Formula:C12H8D7N3O3SColor and Shape:NeatMolecular weight:288.37Temazepam Acetate
CAS:Controlled Product<p>Applications Temazepam Acetate is an impurity of temazepam (T017200), which is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Formula:C18H15ClN2O3Color and Shape:White To Off-WhiteMolecular weight:342.785-Methyl Zolpidem
CAS:Controlled Product<p>Applications An impurity of Zolpidem (Z650000).<br></p>Formula:C19H21N3OColor and Shape:NeatMolecular weight:307.393-(1H -Benzoimidazol-2-yl)-propylamine hydrochloride
CAS:Formula:C10H14ClN3Purity:95.0%Color and Shape:Grey powderMolecular weight:211.692,4-Dichloro-b-[(2,4-dichlorophenyl)methoxy]benzeneethanamine
CAS:Controlled Product<p>Impurity Miconazole EP Impurity C<br>Stability Hygroscopic<br>Applications 2,4-Dichloro-β-[(2,4-dichlorophenyl)methoxy]benzeneethanamine (Miconazole EP Impurity C) is an impurity of Miconazole (M342500).<br>References DeNinno, M.P., J. Med. Chem., 33, 2950 (1990), MacKenzie, R., et al.: J. Med. Chem., 34, 2561 (1991), Katerinopoulos, H.E., et al.: Eur. J. Med. Chem., 30, 949 (1995),<br></p>Formula:C15H13Cl4NOColor and Shape:NeatMolecular weight:365.081’-Hydroxy Midazolam-13C3
CAS:Controlled Product<p>Applications A labelled metabolite of Midazolam (M343000).<br>References Dundee, J., et al.: Drugs, 28, 519 (1984), Galetin, A., et al.: Drug Metab. Dispos., 30, 1512 (2002), Uchaipichat, V., et al.: Drug Metab. Dispos., 34, 449 (2006), Lewis, B., et al.: Biochem. Pharmacol., 73, 1463 (2007),<br></p>Formula:C3C15H13ClFN3OColor and Shape:NeatMolecular weight:344.74Keto Itraconazole
CAS:Controlled ProductFormula:C35H36Cl2N8O5Color and Shape:NeatMolecular weight:719.624-(2-Methylpropyl)piperidine-2,6-dione
CAS:Formula:C9H15NO2Color and Shape:White SolidMolecular weight:169.22rel-(R,R)-Voriconazole
CAS:Controlled Product<p>Applications The (R,R)-enantiomer of Voriconazole. An antifungal (systemic). An ergosterol biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997),<br></p>Formula:C16H14F3N5OColor and Shape:NeatMolecular weight:349.311'-Hydroxy Midazolam-β-D-glucuronide
CAS:Controlled Product<p>Applications The major metabolite of Midazolam (M343000(P)). Midazolam is an anesthetic; anticonvulsant; sedative; hypnotic. It is a positive allosteric modulator of the GABAA receptor.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C24H21ClFN3O7Color and Shape:White To Off-WhiteMolecular weight:517.89PD 312236, PD 312237 Mixture
CAS:<p>Applications PD 312236 is a pyranoside lactose conjugate degradation product of pregabalin (P704800), a GABA analogue used as an anticonvulsant.<br>References Lovdahl, M.J., et al.: J. Pharma. Biomed. Anal., 28, 917 (2002);<br></p>Formula:C20H35NO11Color and Shape:NeatMolecular weight:465.49Piracetam-d8
CAS:Controlled Product<p>Applications Labelled Piracetam (P500800). Nootropic.<br>References Gobert, J., et al.: J. Pharm. Belg., 27, 281 (1972), Oosterveld, W.J., et al.: Arzneim.-Forsch., 30, 1947 (1980), Chouinard, G., et al.: Psychopharmacol. Bull., 17, 129 (1981),<br></p>Formula:C6D8H2N2O2Color and Shape:NeatMolecular weight:150.21[2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl](2-fluorophenyl)-methanone Dihydrochloride
CAS:Controlled ProductFormula:C18H15ClFN3O• 2(HCl)Color and Shape:White To YellowMolecular weight:343.784,4',4''-Methylidynetrisbenzonitrile (Letrozole Impurity)
CAS:<p>Impurity Letrozole EP Impurity B<br>Applications 4,4',4''-Methylidynetrisbenzonitrile (Letrozole EP Impurity B) is a Letrozole isomeric impurity.<br></p>Formula:C22H13N3Color and Shape:Off-WhiteMolecular weight:319.36N-Ethyl-N-methyl-3-vinylphenyl Carbamate
CAS:Controlled Product<p>Impurity Rivastigmine USP Related Compound F<br>Stability Light Sensitive<br>Applications A related compound of Rivastigmine (R541000), a cholinesterase inhibitor. Rivastigmine USP Related Compound F.<br></p>Formula:C12H15NO2Color and Shape:White SolidMolecular weight:205.252,3-Dichlorobenzoyl Nitrile
CAS:Controlled Product<p>Applications 2,3-Dichlorobenzoyl Nitrile is an impurity of Lamotrigine (L173250), an anticonvulsant that is used in the treatment of bipolar and depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rao, S.N., et al.: Int. J. Pharma. Pharmaceut. Sci., 4, 133 (2012); Qian, Y., et al.: J. Chem. Sci., 121, 463 (2009);<br></p>Formula:C8H3Cl2NOColor and Shape:NeatMolecular weight:200.02
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