Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10373 products of "Benzimidazole and Imidazole Derivatives"
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N-Methyl Pantoprazole(Mixture of 1 and 3 isomers)
CAS:<p>Impurity Pantoprazole EP Impurity D;<br>Applications N-Methyl Pantoprazole (Pantoprazole EP Impurity D) is an impurity of Omeprazole and Pantoprazole. Mixture of 1 and 3 isomers (mixture of impurity D and F).<br>References McClean, S., et al.: Anal. Chim. Acta, 292, 81 (1994), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997), Avgerinos, A., et al.: Eur. J. Drug Metab. Pharmacokinet., 23, 329 (1998), Wahbi, A., et al.: J. Pharm. Biomed. Anal., 30, 1133 (2002),<br></p>Formula:C17H17F2N3O4SColor and Shape:Light RedMolecular weight:397.40Scopolamine N-Oxide
CAS:<p>Stability Hygroscopic<br>Applications Scopolamine N-Oxide is an impurity of Scopolamine (S200000), an acetylcholine antagonist used in the treatment of motion sickness and also used as antiemetic, antispasmodic, mydriatic, preanesthetic agents.<br>References Shahwar, D., et al.: Turk. J. Chem., 36, 257 (2012); Paula, S., et al.: J. Med. Chem., 47, 133 (2004); Wu, H.L., et al.: J. Chromatograph. A., 802, 107 (1998); Phillipson, J.D., et al.: J. Pharma. Pharmcol., 25, 116 (1973);<br></p>Formula:C17H21NO5Color and Shape:NeatMolecular weight:319.35Lansoprazole
CAS:<p>Applications Used as a gastric proton pump inhibitor. An antiulcerative. May limit the severity of tuberculosis (see Chem. and Eng. News. p. 28 July 20 (2018)).<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006), Chem. and Eng. News. p. 28 July 20 (2018)<br></p>Formula:C16H14F3N3O2SColor and Shape:White To Light BeigeMolecular weight:369.36Tropicamide
CAS:<p>Applications Ophthalmic anticholinergic. Mydriatic.<br>References Blessel, K.W., et al.: Anal. Profiles Drug Subs., 3, 565 (1974), Krapivinsky, G., et al.: J. Biol. Chem., 270, 29059 (1995), Bedingfield, J., et al.: Eur. J. Pharmacol., 309, 71 (1996), Jin, W., et al.: Biochemistry, 38, 14294 (1999), Kew, J., et al.: Pharmacol. Ther., 104, 233 ( 2004), Bertaso, F., et al.: J. Neurochem., 99, 288 (2006),<br></p>Formula:C17H20N2O2Color and Shape:NeatMolecular weight:284.35Tinidazole
CAS:Controlled Product<p>Applications Antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.<br>References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),<br></p>Formula:C8H13N3O4SColor and Shape:Off-White To Light YellowMolecular weight:247.274-Nitro-2,3-lutidine N-Oxide
CAS:Controlled Product<p>Applications Nitropyridine oxide derivatives show carcinogenicity and mutagenicity.<br>References Nagao, M., et al.: Cancer Res., 32, 2369 (1972),<br></p>Formula:C7H8N2O3Color and Shape:NeatMolecular weight:168.15Miconazole Impurity B
CAS:Controlled Product<p>Applications Miconazole Impurity B, is the impurity of Miconazole (M342500), which is an imidazole antifungal agent, that is applied topically to the skin or to mucus membranes for the treatment of fungal infections.<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H15Cl3N2OColor and Shape:NeatMolecular weight:381.683-Methoxy-temazepam
CAS:Controlled ProductFormula:C17H15ClN2O2Color and Shape:Off-White To Light YellowMolecular weight:314.77Triazolam
CAS:Controlled Product<p>Applications Sedative, hypnotic.Controlled substance (depressant).<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976), Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978), Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>Formula:C17H12Cl2N4Color and Shape:WhiteMolecular weight:343.21Ronidazole-d3
CAS:Controlled Product<p>Applications Labelled Ronidazole (R640200). Antimicrobial.<br>References Yamada, R., et al.: Biosci. Biotechnol. Biochem., 70, 54 (2006), Mohamed, R., et al.: J. Agric. Food Chem., 56, 3500 (2008), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009),<br></p>Formula:C62H3H5N4O4Color and Shape:Off-WhiteMolecular weight:203.17Imidacloprid-d4
CAS:Controlled Product<p>Applications Imidacloprid-d4 is labelled Imidacloprid (I274990) which is a neonicotinoid, the active ingredient in certain neuro-active insecticides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:C92H4H6ClN5O2Color and Shape:WhiteMolecular weight:259.692-Methoxy-4-(6-nitro-1H-benzo[d]imidazol-2-yl)phenol
CAS:Purity:97%Molecular weight:285.25900268554692-(benzylthio)-1H-benzimidazole
CAS:Purity:95.0%Color and Shape:Solid, White powderMolecular weight:240.320007324218754-Methoxy-2-(((6-methoxy-1H-benzo[d]imidazol-2-yl)sulfonyl)methyl)-3,5-dimethylpyridine 1-oxide
CAS:Purity:95.0%Molecular weight:377.42001342773442-(4-Morpholinyl)-1H-benzimidazole
CAS:Purity:95.0%Color and Shape:Solid, White powderMolecular weight:203.24499511718752-(2-Aminoethyl)-1-methyl-1H-imidazole x 2 HCl
CAS:Formula:C6H13Cl2N3Purity:98.0%Color and Shape:Liquid, No data available.Molecular weight:198.09Thiabendazole-d4 (Major)
CAS:Controlled ProductFormula:C10D4H3N3SColor and Shape:Off WhiteMolecular weight:205.27rac Desethyl Oxybutynin-d11 Hydrochloride
CAS:Controlled ProductFormula:C20D11H16NO3·HClColor and Shape:NeatMolecular weight:376.96N-(2-Hydroxyethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide
CAS:<p>Applications N-(2-Hydroxyethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide is a photolysis product of Metronidazole (M338880), an antibiotic.<br>References Moore, Douglas E., et al.: Radiation Phy. and Chem., 36(4), 547-50 (1990)<br></p>Formula:C6H9N3O3Color and Shape:NeatMolecular weight:171.1542-(4-Chlorobenzyl)-1H-benzimidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:242.71000671386725-Methyl-2-phenoxypyridine
CAS:Controlled ProductFormula:C12H11NOColor and Shape:NeatMolecular weight:185.232-(((6-(Difluoromethoxy)-1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-3,4-dimethoxypyridine 1-oxide
CAS:Purity:95.00%Molecular weight:399.3699951171875(R)-3-Boc-4-(Methoxymethylcarbamoyl)-2,2-dimethyloxazolidine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:288.343994140625(1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-8-azabicyclo[3.2.1]oct-6-en-8-ium Bromide
CAS:Controlled Product<p>Impurity Tiotropium bromide EP impurity C<br>Applications (1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-8-azabicyclo[3.2.1]oct-6-en-8-ium Bromide is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.<br>References Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);<br></p>Formula:C19H22NO3S2·BrColor and Shape:NeatMolecular weight:456.42Albendazole Sulfone
CAS:<p>Impurity Albendazole EP Impurity C / Albendazole Sulfone<br>Applications A metabolite of Albendazole, an anthelmintic. Albendazole EP Impurity C<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol. Lett., 6, 2: 51 (1996)<br></p>Formula:C12H15N3O4SColor and Shape:BeigeMolecular weight:297.33(R)-Rabeprazole Sodium Salt
CAS:Controlled Product<p>Applications A partially reversible gastric proton pump inhibitor.<br>References Moda, T., et al.: Lett. Drug Des. Discov., 4, 502 (2007), Belaz, K., et al.: J. Pharm. Biomed. Anal., 47, 81 (2008),<br></p>Formula:C18H20N3NaO3SColor and Shape:NeatMolecular weight:381.422-Isobutyl-1H-benzoimidazol-5-ylamine
CAS:Formula:C11H15N3Purity:98%Color and Shape:SolidMolecular weight:189.2628-amino-2-(1H-1,2,3,4-tetrazol-5-yl)-4H-chromen-4-one hydrochloride
CAS:Purity:98%Molecular weight:265.6600036621094Ravuconazole-d4
CAS:Controlled Product<p>Applications Ergosterol biosynthesis inhibitor. Antifungal.<br>References Fung-Tomc., J.C., et al.: Antimicrob. Agents Chemother., 42, 313 (1988), Tsuruoka, A., et al.: Chem. Pharm. Bull., 46, 623 (1998), Gupta, A.K., et al.: J. Eur. Acad. Dermatol. Venereol., 19, 437 (2005),<br></p>Formula:C22H13D4F2N5OSColor and Shape:NeatMolecular weight:441.49Parbendazole
CAS:Controlled Product<p>Applications Parbendazole is a benzimidazole carbamate and a potent inhibitor of microtubule assembly and functions.<br>References Lahon, L.C.. et al.: Ind. J. Pharmacol., 26, 235 (1994); Havercroft, J.C., et al.: J. Cell. Sci., 49, 195 (1981);<br></p>Formula:C13H17N3O2Color and Shape:NeatMolecular weight:247.293-(2-Amino-2-oxoethyl)-5-methylhexanoic Acid
CAS:Formula:C9H17NO3Color and Shape:NeatMolecular weight:187.24a-Descyclohexyl-a-phenyl Oxybutynin
CAS:Controlled Product<p>Impurity Oxybutynin EP Impurity B<br>Applications α-Descyclohexyl-α-phenyl Oxybutynin (Oxybutynin EP Impurity B) is an Oxybutynin impurity; 4-(dialkylamino)-2-butynyl benzilates as parasympatholytic substances.<br>References Dahlbom, R., et al.: Acta Chem. Scand., 17, 2354 (1963),<br></p>Formula:C22H25NO3Color and Shape:NeatMolecular weight:351.44N-Methyl-1-(oxazol-2-yl)methanamine
CAS:Formula:C5H8N2OPurity:95.0%Color and Shape:LiquidMolecular weight:112.132Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone
CAS:Controlled Product<p>Applications Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Formula:C31H28N2OColor and Shape:NeatMolecular weight:444.572,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
CAS:Controlled Product<p>Applications Varenicline intermediate.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005),<br></p>Formula:C13H14F3N3OColor and Shape:NeatMolecular weight:285.268-Chloro-6-(2-fluorophenyl)-1-methyl-6H-Imidazo[1,5-a][1,4]benzodiazepine
CAS:Controlled Product<p>Impurity MIdazolam EP Impurity B<br>Applications 8-Chloro-6-(2-fluorophenyl)-1-methyl-6H-Imidazo[1,5-a][1,4]benzodiazepine is an isomer of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Walser, A., et al.: J. Org. Chem., 43, 936 (1978); Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3Color and Shape:NeatMolecular weight:325.774-(1H-Benzoimidazol-2-yl)-1-phenyl-pyrrolidin-2-one
CAS:Purity:95.0%Molecular weight:277.32699584960941-[2-(2-Chlorophenoxy)ethyl]-1H-benzoimidazol-2-ylamine
CAS:Formula:C15H14ClN3OColor and Shape:SolidMolecular weight:287.752-Methyllamotrigine Methanesulfonate
CAS:<p>Applications 2-Methyl-Lamotrigine is an impurity of Lamotrigine (L173250), an anticonvulsant which inhibits glutamate release, possible through inhibition of sodium, potassium and calcium currents. Used in treatment of bipolar depression.<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986), Grunze, et al.: Neuropsychobiology, 38, 131 (1998), Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999),<br></p>Formula:C10H9Cl2N5·CH4O3SColor and Shape:Off White SolidMolecular weight:366.22
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