Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10373 products of "Benzimidazole and Imidazole Derivatives"
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2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole
CAS:<p>2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole is a protonated sulfonamide that is used as an analytical method to detect the presence of other drugs in human liver tissue. It has been shown to inhibit the activity of cytochrome P450 3A4 (CYP3A4), one of the enzymes responsible for metabolizing many drugs. Bromoenol lactone and powder diffraction spectrum are two additional analytical methods that can be used to detect 2-[([(4-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole.</p>Formula:C18H21N3O4SPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:375.44 g/molOmeprazole impurity F and G
CAS:<p>Omeprazole is a proton pump inhibitor that inhibits the H+/K+-ATPase enzyme in gastric parietal cells. Omeprazole impurity F and G are metabolites of omeprazole. Omeprazole impurity F is a metabolite of omeprazole that forms by oxidation of the methylthio group in omeprazole to form a sulfoxide. Omeprazole impurity G is formed by hydrolysis of the methylthio group in omeprazole to form an alcohol. The purity of this product is high and can be custom synthesized based on customer's needs. It is also available as an HPLC standard or as an API impurity for use in metabolism studies.</p>Formula:C16H13N3O2SPurity:Min. 95%Color and Shape:Red PowderMolecular weight:311.36 g/mol5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole
CAS:<p>5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole is a natural product. It is an impurity in the drug development process and may be present as an analytical marker for impurities. 5-Methoxy-2-[(3,5-dimethylpyridinium)methyl]sulfinyl]-1Hbenzimidazole is used as a pharmacopoeia standard and can be synthesized on request.</p>Formula:C16H17N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:315.39 g/molPantoprazole sodium hydrate - Mixture of impurities D and F
CAS:<p>Pantoprazole sodium hydrate is a custom synthesis that is used as a drug product. The CAS number for this compound is 624742-53-6. This compound has the following impurities: D and F. Pantoprazole sodium hydrate has been shown to be metabolized in vitro by human liver microsomes to its metabolites, including the following: (1) pantoprazol acid, (2) 4-hydroxypantoprazol acid, (3) 4-hydroxyisoxazole acid, and (4) 5-(4-hydroxyphenyl)-2H-1,2-benzoxazin-3(4H)-one. The metabolite 4-hydroxypantoprazol acid has been found to be pharmacologically active in animal models of gastric ulceration and healing.</p>Formula:C17H17F2N3O4SPurity:Min. 95%Color and Shape:Off-white to yellow powder.Molecular weight:397.4 g/mol(R)-5-Hydroxymethyl tolterodine
CAS:<p>(R)-5-Hydroxymethyl tolterodine is a prodrug that is metabolized by cytochrome P450 3A4 (CYP3A4) in the liver to its active form, tolterodine. This drug can be used as an alternative for gabapentin in the treatment of detrusor muscle overactivity associated with neurogenic bladder dysfunction. The pharmacokinetic properties of (R)-5-hydroxymethyl tolterodine are similar to those of gabapentin, including the elimination half-life and volume of distribution. However, unlike gabapentin, which has been shown to increase the glomerular filtration rate (GFR) and renal blood flow, there is no evidence that this drug has any effect on GFR or renal blood flow. There is also no evidence that (R)-5-hydroxymethyl tolterodine causes any symptoms that may be attributed to</p>Formula:C22H31NO2Purity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:341.49 g/mol2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
CAS:<p>2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].</p>Formula:C15H15N3OS2Purity:Min. 95%Molecular weight:317.43 g/mol5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one (donepezil impurity)
CAS:<p>5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one (donepezil impurity) is an analytical standard used as a reference in HPLC assays for donepezil. It is also a metabolite of donepezil and has been found to have pharmacological activity similar to that of the parent compound. This impurity is present in donepezil drug products at levels up to 0.5%.</p>Formula:C17H21NO3Purity:Min. 95%Molecular weight:287.35 g/mol2-Hydroxybenzimidazole
CAS:<p>2-Hydroxybenzimidazole is a benzimidazole compound that is used in the treatment of nervous system diseases. It has been shown to have anti-inflammatory properties and can be used in the treatment of syncytial virus infection. 2-Hydroxybenzimidazole inhibits the production of reactive oxygen species and nitric oxide, which are involved in neurodegenerative disorders. The mechanism of action for 2-Hydroxybenzimidazole involves the formation of hydrogen bonds with hydroxyl groups on proteins. It also has been shown to reduce locomotor activity and increase sleep time in mice, which may be due to inhibition of acetylcholine release from cholinergic neurons.</p>Formula:C7H6N2OPurity:Min. 97.5 Area-%Color and Shape:Off-White PowderMolecular weight:134.14 g/mol1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine
CAS:<p>1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine is an analytical standard and a drug product. It is a synthetic compound that has been shown to have pharmacological effects similar to those of the analgesic or opioid drugs. 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine can be used as an impurity standard for HPLC analyses as well as metabolic studies. This compound is also known to have potential interactions with other drugs.</p>Formula:C24H27NO3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:377.48 g/molPantoprazole sulfide N-oxide
CAS:<p>Pantoprazole sulfide N-oxide is a metabolite of pantoprazole, which is a proton pump inhibitor used to reduce stomach acid production. Pantoprazole sulfide N-oxide is an impurity in pantoprazole that can be detected by HPLC. It has been shown to have about the same biological activity as pantoprazole when given orally.</p>Formula:C16H15F2N3O4SPurity:Min. 95%Color and Shape:Off-White To Yellow SolidMolecular weight:383.37 g/molN-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide
CAS:<p>N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide is a pharmaceutical dosage form that is titrated to achieve the desired therapeutic effect. It is used to treat epilepsy and bipolar disorder. Lamotrigine binds to sodium channels in nerve cells and blocks their opening. This prevents the influx of sodium ions that are necessary for neuronal transmission. Lamotrigine has been shown to have an anticonvulsant effect by reducing the frequency of seizures in patients with epilepsy.</p>Formula:C16H9Cl4N5OPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:429.09 g/mol6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine
CAS:<p>6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is a metabolite that can be found in the urine and blood of humans. It has been shown to have cytotoxic effects on human lymphocytes and erythrocytes. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is used as an impurity standard for HPLC analysis and as a reference compound for pharmacopoeia. This chemical is also used in the synthesis of some drugs. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is not listed in any pharmacopoeia or natural product database.</p>Formula:C9H7Cl2N5Purity:Min. 95%Color and Shape:White PowderMolecular weight:256.09 g/mol2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt
<p>2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt is a white to off-white crystalline powder. It is soluble in water and sparingly soluble in alcohol. This product is used as an analytical standard and has been found to be a metabolite of the drug clozapine. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt has also been found to be an impurity in the drug product lamotrigine.</p>Formula:C24H29NO5•NaPurity:Min. 95%Molecular weight:434.49 g/molRabeprazole Impurity 2
CAS:<p>Rabeprazole Impurity 2 is a research and development impurity standard that is used for qualitative analysis. It can be custom synthesized to meet specific needs, and it can also be used in drug product synthesis. Rabeprazole Impurity 2 is a high purity synthetic compound that has been pharmacopoeia-qualified. It can also be used as a metabolite or analytical standard, and it has been studied for its metabolism studies with HPLC-MS. Rabeprazole Impurity 2 has CAS No. 1807988-36-8.</p>Formula:C18H19N3O4Purity:Min. 95%Molecular weight:341.36 g/mol6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione
CAS:<p>6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione is a chlorinating agent that converts alcohols to alkyl chlorides. It is used for the conversion of diazotizable aromatic compounds to diazo compounds. This compound has been shown to be neuroprotective in animal models and provides protection against glutamate excitotoxicity. 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione also reacts with nitrite ions to form the corresponding nitroso derivatives. These derivatives can cause DNA damage and are mutagenic. 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5(2H,4H)-dione has been shown to react with aminoguanidine to produce a chromat</p>Formula:C9H5Cl2N3O2Purity:Min. 95%Color and Shape:PowderMolecular weight:258.06 g/mol2,3-Dichlorobenzoic acid
CAS:<p>2,3-Dichlorobenzoic acid is an organic compound that belongs to the class of carboxylates. It is used as a drug substance in the treatment of mycobacterial infections. 2,3-Dichlorobenzoic acid has been shown to have antimicrobial activity against Mycobacterium tuberculosis and other mycobacteria. The sensitivity index for this compound was determined using a chromatographic method with human erythrocytes as the test organism. 2,3-Dichlorobenzoic acid displays its antibacterial activity by inhibiting protein synthesis and cell division. This drug also forms crystalline solids that are soluble in organic solvents such as chloroform or benzene.</p>Formula:C7H4Cl2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:191.01 g/mol2-Hydroxy-2,2-bis(2-thienyl) acetic acid
CAS:<p>2-Hydroxy-2,2-bis(2-thienyl) acetic acid is a long-acting bronchodilator that can be administered by inhalation. It has been used in the clinical development of medicines for the treatment of asthma and chronic obstructive pulmonary disease. 2-Hydroxy-2,2-bis(2-thienyl) acetic acid is chemically related to pyridinium compounds. It is a potent inhibitor of muscarinic receptors and has an anticholinergic profile similar to atropine. The safety profile of this drug seems to be favourable in humans with no major side effects reported so far.</p>Formula:C10H8O3S2Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:240.3 g/mol5-Methoxy-2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole
CAS:<p>5-Methoxy-2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H benzimidazole is a synthetic drug product. It has been used as a positive control in metabolism studies and as an impurity standard. 5-Methoxy 2-[(4-chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfinyl]-5 methoxy 1H benzimidazole is also a metabolite of the active pharmaceutical ingredient (API) which is used to develop drugs. This chemical is synthesized by custom synthesis and can be obtained at high purity levels. The metabolite of this compound is 5 methoxy 2-[(4 chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfonyl]-5 methoxy 1H benzimidazole.</p>Formula:C16H16ClN3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:349.84 g/molVarenicline
CAS:<p>Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.</p>Formula:C13H13N3Purity:99.76%Color and Shape:SolidMolecular weight:211.26Ethyl 4-amino-1-methyl-1H-imidazole-5-carboxylate
CAS:Formula:C7H11N3O2Purity:98%Color and Shape:SolidMolecular weight:169.184tert-butyl N-[(1S)-1-[4-(4-bromophenyl)-1H-imidazol-2-yl]-2-methylpropyl]carbamate
CAS:Purity:98%Molecular weight:394.3131-Methyl-3-octyl-1H-imidazol-3-ium bis(2,2,2-trifluoroacetyl)amide
CAS:Purity:97%Molecular weight:403.369(3-METHYL-1H-INDAZOL-6-YL)BORONIC ACID PINACOL ESTER
CAS:Formula:C14H19BN2O2Purity:98%Color and Shape:SolidMolecular weight:258.132-METHYLINDAZOLE-7-BORONIC ACID
CAS:Formula:C8H9BN2O2Purity:95%Color and Shape:SolidMolecular weight:175.984-(1H-IMIDAZOL-1-YLMETHYL)BENZOIC ACID
CAS:Formula:C11H10N2O2Purity:97%Color and Shape:SolidMolecular weight:202.213TERT-BUTYL 3-METHYL-5-NITRO-1H-INDAZOLE-1-CARBOXYLATE
CAS:Formula:C13H15N3O4Purity:98%Molecular weight:277.28Ref: 10-F672798
1g797.00€5g2,158.00€10g3,200.00€2.5g1,461.00€50mg210.00€100mg299.00€250mg414.00€500mg633.00€2-(Piperidin-3-yl)-1H-benzo[d]imidazole
CAS:Formula:C12H15N3Purity:95%Color and Shape:SolidMolecular weight:201.2732-Methyl-1H-imidazole-4-carboxylic acid
CAS:Formula:C5H6N2O2Purity:95%Color and Shape:SolidMolecular weight:126.1156-Bromo-3-chloro-1H-indazole
CAS:Formula:C7H4BrClN2Purity:98%Color and Shape:Solid, Yellow solidMolecular weight:229.9251H-Benzimidazole-5-boronic acid pinacol ester
CAS:Formula:C13H17BN2O2Purity:95%Color and Shape:SolidMolecular weight:244.1(4-FLUORO-1-ISOPROPYL-2-METHYL-1H-BENZO[D]IMIDAZOL-6-YL)BORONIC ACID PINACOL ESTER
CAS:Formula:C17H24BFN2O2Purity:95%Color and Shape:SolidMolecular weight:318.25-Methyl-6-nitro-1H-indazole
CAS:Formula:C8H7N3O2Purity:98%Color and Shape:SolidMolecular weight:177.0547-Bromo-5-(trifluoromethyl)-1H-indazole
CAS:Formula:C8H4BrF3N2Purity:97%Color and Shape:Solid, No data available.Molecular weight:265.033
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