Purines and Pyrimidine Derivatives
Purines have a bicyclic structure, consisting of a six-membered ring fused to a five-membered ring, both containing nitrogen atoms in key positions. Purine derivatives, such as adenine and guanine, are essential for the formation of DNA and RNA. These compounds have therapeutic applications in cancer and viral disease treatments by inhibiting cell replication. Pyrimidines, on the other hand, have a monocyclic six-membered structure with two nitrogen atoms. Their derivatives, such as cytosine, thymine, and uracil, are also essential components of DNA and RNA and are used in chemotherapy and antiviral treatments.
At CymitQuimica, we offer purine and pyrimidine derivatives for research in molecular biology, genomics, and the development of innovative therapies.
Found 8902 products of "Purines and Pyrimidine Derivatives"
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4-Amino-1,3-dimethyl-5-nitrosouracil x-H2O
CAS:Controlled Product<p>Applications 4-Amino-1,3-dimethyl-5-nitrosouracil is a useful building block for organic synthesis.<br></p>Formula:C6H8N4O3Color and Shape:NeatMolecular weight:184.15Methotrexate (1 mg/mL in Methanol with 0.1N NaOH)
CAS:Formula:C20H22N8O5Color and Shape:Single SolutionMolecular weight:454.443,5-Dimethyl-1-adamantanol
CAS:Controlled Product<p>Impurity Memantine USP Related Compound B (3,5-Dimethyladamantane-1-ol)<br>Applications 3,5-Dimethyl-1-adamantanol is an impurity of Memantine (M218000). Memantine impurity B. Memantine USP Related Compound B (3,5-Dimethyladamantane-1-ol).<br>References England, P., et al.: Biochemistry, 43, 11623 (2004), Schousboe, A., et al.: Eur. J. Pharmacol., 500, 281 (2004), Horvat, S., et al.: J. Med. Chem., 49, 3136 (2006),<br></p>Formula:C12H20OColor and Shape:WhiteMolecular weight:180.295-Cyclopropyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one
CAS:Formula:C7H8N2OSPurity:95.0%Color and Shape:SolidMolecular weight:168.213-Amino-4-carbamoylpyrazole Hemisulfate
CAS:Controlled Product<p>Impurity Allopurinol EP Impurity A / Allopurinol USP Related Compound A<br>Stability Hygroscopic<br>Applications 3-Amino-4-carbamoylpyrazole Hemisulfate (Allopurinol EP Impurity A) is an impurity of Allopurinol (A547300), a pyrazole derivative that has been shown to induce neoplasm immunogenicity.<br>References Nicolin, A. et al.: Cancer, Chemother. Rep., 57, 3 (1973); Bonmassar, E. et al.: Cancer Res., 35, 1957 (1975);<br></p>Formula:C4H6N4O·H2O4SColor and Shape:White To Light BrownMolecular weight:350.312-Isopropyl-pyrimidine-5-carboxylic acid
CAS:Formula:C8H10N2O2Purity:95.0%Color and Shape:SolidMolecular weight:166.18Iso Rizatriptan
CAS:Controlled Product<p>Impurity Rizatriptan EP Impurity C<br>Applications Iso Rizatriptan (Rizatriptan EP Impurity C) is a potential impurity of Rizatriptan. A regioisomer of Rizatriptan.<br>References Dill, K., et al.: J. Phys. Chem., 91, 1980 (1987), Cole, L., et al.: Anal. Chem., 64, 1317 (1992), Street, L., et al.: J. Med. Chem., 1995, 38, 1799<br></p>Formula:C15H19N5Color and Shape:NeatMolecular weight:269.34N-Butyldeoxynojirimycin Hydrochloride
CAS:Controlled Product<p>Applications An inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. N-Butyldeoxynojirimycin has recently been used to retard lipid storage in the central nervous system of an animal model of Tay-Sachs disease.1-Deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man.<br>References Hettkamp, H., et al.: Eur. J. Biochem., 142, 85 (1984), Szumilo, T., et al.: Arch. Biochem. Biophys., 247, 261 (1986), Fleet, G.W.J., et al.: FEBS Letters, 237, Number 1,2, 128 (1988), Kolter, T., et al.: Angew. Chem. Int. Ed. Engl., 36, 1955 (1997),<br></p>Formula:C10H21NO4·ClHColor and Shape:NeatMolecular weight:255.742-[(2-Amino-6-chloro-4-pyrimidinyl)amino]ethanol
CAS:Purity:95.0%Color and Shape:Solid, Yellow powderMolecular weight:188.61999511718754-Hydroxythiobenzamide
CAS:<p>Applications 4-Hydroxythiobenzamide is used in the synthesis of PPARα agonists used in increasing HDLc levels. Also used in the synthesis of potent CDK5 inhibitors in the treatment of Alzheimer’s disease.<br>References Sierra, M. et al.: J. Med. Chem., 50, 685 (2007); Zhong, W. et al.: Bioorg. Med. Chem. Lett., 17, 5384 (2007);<br></p>Formula:C7H7NOSColor and Shape:NeatMolecular weight:153.2N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyladenosine
CAS:Purity:95%Molecular weight:687.753Iopamidol-d8
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Iopamidol, a nonionic radiocontrast medium. Diagnostic aid (radiopaque medium).<br>References Drayer, B., et al.: Am. J. Neuroradiol., 3, 59 (1982); Molyneux, A.J., et al.: Br. J. Radiol., 55, 117 (1982); Sovak, M., et al.: Radiology, 142, 115 (1982); Felder, E., et al.: Anal. Profiles Drug Subs., 17, 115 (1988);<br></p>Formula:C17H14D8I3N3O8Color and Shape:NeatMolecular weight:785.136-Methyl-2-methylsulfanyl-3H-pyrimidin-4-one
CAS:Purity:98.0%Color and Shape:Solid, CrystallineMolecular weight:156.1999969482422Mono-POC Isopropyl Tenofovir(Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Tenofovir (T018500) impurity.<br></p>Formula:C17H28N5O7PColor and Shape:White SolidMolecular weight:445.416,6'-Binicotinic Acid
CAS:Controlled Product<p>Applications A Nicotinic acid (N429250) derivative for treatment of hypercholesterolemia and hyperlipidemia and cardiovascular disease.<br>References Hales, N.J., et al.: J. Med. Chem., 36, 3853 (1993),<br></p>Formula:C12H8N2O4Color and Shape:NeatMolecular weight:244.20Pentostatin
CAS:Controlled Product<p>Applications An adenosine deaminase inhibitor used as an anti-cancer therapeutic drug. Shown to be effective in the treatment of hairy cell leukemia as well as having use in the treatment of other types of cancer such as chronic lymphocytic leukemia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rogler-Brown, T. et al.: Biochem. Pharmacol., 28, 201 (1979); Johnston, J.B. et al.: J. Natl. Canvcer Inst., 80, 765 (1988); Fortune, A.F. et al.: Leuk. and Lymph., 51, 839 (2010); Robak, T. et al.: Drugs, 69, 2415 (2009);<br></p>Formula:C11H16N4O4Color and Shape:White To Off-WhiteMolecular weight:268.27Paraxanthine
CAS:<p>Stability Store tightly sealed at RT<br>Applications Paraxanthine is an adenosine receptor ligand and a major metabolite of caffeine.This compound is a contaminant of emerging concern (CECs).<br>References Proc. Natl. Acad. Sci. USA 78, 3260 (1981); Cell Mol. Neurobiol., 3, 69 (1983); Eur. J. Pharmacol., 179, 295 (1990)<br></p>Formula:C7H8N4O2Color and Shape:White To Light YellowMolecular weight:180.16
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