Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65924 products of "Quinazoline and Quinoline Derivatives"
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4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide
CAS:<p>Applications 4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide is an impurity of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Formula:C15H17N3O2SColor and Shape:White To Light YellowMolecular weight:303.384-ethyl-N-(pyridin-4-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.3699951171875Sibutramine, Hydrochloride Monohydrate
CAS:Controlled ProductFormula:C17H26ClN·ClH·H2OColor and Shape:Off White SolidMolecular weight:334.32Propiconazole
CAS:Controlled Product<p>Applications Propiconazole is a systemic foliar fungicide. Agricultural fungicide. Useful in cannabis testing kits as a component of pesticide mixes (P698235).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Child, R., et al.: Plant Growth Regul., 13, 203 (1993), Jaleel, C., et al.: Plant Sci., 171, 271 (2006), Jaleel, C., et al.: Pestic Biochem. Physiol., 91, 170 (2008),<br></p>Formula:C15H17Cl2N3O2Color and Shape:YellowMolecular weight:342.221-cyclopropyl-1-(3-methyl-2-pyridinyl)methanamine
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:162.235992431640624-Methyl Erlotinib Hydrochloride
CAS:Controlled Product<p>Applications Erlotinib (E625000) derivative as internal standard for HPLC.<br></p>Formula:C23H25N3O4·ClHColor and Shape:NeatMolecular weight:443.92324-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-ol
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:328.375Levofloxacin N-oxide
CAS:Controlled Product<p>Impurity Oxifloxacin EP Impurity F<br>Applications Levofloxacin N-oxide is an impurity of Ofloxacin (O245750), which is a fluorinated quinolone antibacterial.<br>References Horstkotter, C., et al.: J. Chromatography Biomed. Sci. Appli., 754, 169 (2001); Monk, J.P., et al.: Drugs, 33, 346 (1987), Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990)<br></p>Formula:C18H20FN3O5Color and Shape:NeatMolecular weight:377.371-Benzyl-3-(4-methylphenyl)-1h-pyrazole-4-carboxylic acid
CAS:Purity:97%Molecular weight:292.33801269531255-(4-Fluorophenyl)-2-methyl-4-(4-pyridyl)-1h-pyrimidin-6-one
CAS:Purity:98%Molecular weight:281.2900085449219Vildagliptin Lactam
CAS:<p>Impurity Rac-Vildagliptin Impurity F<br>Applications Vildagliptin Lactam is an impurity of Vildagliptin (V305000). Glyptins are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. ASide from there use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formula:C17H24N2O3Color and Shape:Off-WhiteMolecular weight:304.386-METHYL-N1-(3-METHYL-1-(6-(METHYLAMINO)PYRIMIDIN-4-YL)-1H-PYRAZOL-5-YL)BENZENE-1,3-DIAMINE
CAS:Purity:95.0%Molecular weight:309.37701416015625Cinitapride Tartrate
CAS:<p>Applications Cinitapride Tartrate is the salt analogue of Cinitapride (C441990), a novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors.<br>References Alarcon de la Lastra, C. et al.: Pharmacol, 54, 193 (1997); Robert, M. et al.: Drug Metab. Disp., 35, 1149 (2007); Alarcon de la Lastra, C. et al.: Inflam. Res., 47, 131 (1998)<br></p>Formula:C21H30N4O4·C4H6O6Color and Shape:NeatMolecular weight:552.573,6-Bis(5-bromothiophen-2-yl)-2,5-bis(2-octyldodecyl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione
CAS:Purity:95%Molecular weight:1019.219970703125O-Desmethyl Carvedilol
CAS:Controlled Product<p>Applications A metabolite of Carvedilol (C184625), a nonselective β-adrenergic blocker with α1-blocking activity.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., et al.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Clohs, L., et al.: J. Pharm. Biomed. Anal., 31, 407 (2003),<br></p>Formula:C23H24N2O4Color and Shape:NeatMolecular weight:392.456-Bromo-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester
CAS:Controlled ProductFormula:C19H18BrNO3SColor and Shape:Off White SolidMolecular weight:420.324,7-dimethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.36999511718752-(thiophen-2-yl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine
CAS:Purity:95.0%Molecular weight:230.33000183105472,6-Di(1H-benzo[d]imidazol-2-yl)pyridine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:311.34799194335943-methyl-1-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-5-amine
CAS:Purity:95.0%Molecular weight:256.3299865722656A77 1726-d4
CAS:Controlled Product<p>Applications The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function.<br>References Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)<br></p>Formula:C122H4H5F3N2O2Color and Shape:Off-WhiteMolecular weight:274.232-Ethyl-2-methyl-succinonitrile
CAS:Controlled Product<p>Applications An intermediate in the preparation of Ethosuximide.<br></p>Formula:C7H10N2Color and Shape:NeatMolecular weight:122.17Pefloxacin Mesylate
CAS:Controlled Product<p>Applications Pefloxacin is a fluorinated quinolone antibacterial; analog of Norfloxacin.<br>References Barre, J., et al.: J. Pharm. Sci., 73, 1379 (1984), Contrepois, A., et al.: J. Antimicrob. Chemother., 14, 51 (1984),<br></p>Formula:C17H20FN3O3·CH4O3SColor and Shape:Off-WhiteMolecular weight:429.46Tazarotene
CAS:<p>Applications An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>Formula:C21H21NO2SColor and Shape:Light YellowMolecular weight:351.46(E)-Ethyl 7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-5-hydroxy-3-oxohept-6-enoate
CAS:Purity:96%Molecular weight:447.5060119628906Dimetridazole
CAS:Controlled Product<p>Applications An antihistomonal agent. Antiprotozoal (Histomonas).<br>References Butler, K., et al.: J. Med. Chem., 10, 891 (1967), Mitrovic, M., et al.:; Antimicrob. Agents Chemother., 445, 1968, Mitrovic, M., et al.: Poult. Sci., 49, 86 (1970),<br></p>Formula:C5H7N3O2Color and Shape:NeatMolecular weight:141.133-(3,5-Dimethyl-pyrazol-1-yl)-benzoic acid
CAS:Formula:C12H12N2O2Purity:95.0%Color and Shape:SolidMolecular weight:216.247-(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one
CAS:Purity:98.0%Molecular weight:397.211389724rac Phenylephrine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Phenylephrine is a selective α1-adrenergic receptor agonist used as a decongestant. Phenylephrine lowers intraocular pressure and is used as an agent to dilate the pupil.<br>References Lorenzetti, O.J. et al.: Exp. Eye Res., 12, 80 (1971); Ando, J. et al.: Nip. Yakur. Zas., 61, 471 (1965);<br></p>Formula:C9H14ClNO2Color and Shape:NeatMolecular weight:203.67rac-Paroxetine-d4 Hydrochloride
CAS:Controlled Product<p>Applications rac-Paroxetine-d4 Hydrochloride is a racemic labeled analogue of Paroxetine Hydrochloride (P205750), a selective serotonin reuptake inhibitor. Used as an antidepressant.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978); Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982)<br></p>Formula:C19H17D4ClFNO3Color and Shape:White To Light BrownMolecular weight:369.852,3-Dichlorothiophene-5-sulfonyl chloride
CAS:Formula:C4HCl3O2S2Purity:≥97%Color and Shape:SolidMolecular weight:251.523-(Methoxycarbonyl)thiophene-2-boronic acid
CAS:Purity:95%Color and Shape:SolidMolecular weight:185.99000549316406(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
CAS:Purity:95.0%Molecular weight:345.42001342773443-(1-Methanesulfonyl-3,5-dimethyl-1 H -pyrazol-4-yl)-propionic acid ethyl ester
CAS:Formula:C11H18N2O4SPurity:97%Color and Shape:SolidMolecular weight:274.34Rizatriptan
CAS:Rizatriptan (Risatriptan) is a selective 5-hydroxytryptamine 1B/1D receptor agonist used in the study of migraine.Formula:C15H19N5Purity:99.74%Color and Shape:SolidMolecular weight:269.35Bupivacaine-d9 Hydrochloride
CAS:Controlled Product<p>Applications Labelled Bupivacaine (B689560). Sodium channel blocker, local anesthetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wilson, T.D., et al.: Anal. Profiles Drug Subs., 19, 59 (1990), McClellan, K.J., et al.: Drugs, 56, 355 (1998),<br></p>Formula:C182H9H19N2O·ClHColor and Shape:NeatMolecular weight:333.944-((Chloromethyl)sulfonyl)morpholine
CAS:Formula:C5H10ClNO3SPurity:95.0%Color and Shape:No data available.Molecular weight:199.656-(methylsulfonyl)-N-(pyridin-3-ylmethyl)benzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:319.39999389648441-(4-Pyridyl)-1,2,3,4-tetrahydro isoquinoline
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:210.27999877929688(1,3-benzodioxol-5-ylmethyl)(2-pyridinylmethyl)amine dihydrobromide
CAS:Purity:95.0%Molecular weight:404.101989746093754-Amino-3,5-dichloropyridine
CAS:<p>Applications 4-Amino-3,5-dichloropyridine is a metabolite of the selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast (R639700).<br>References Jeffrey, A.D. et al.: Drug Chem. Toxicol., 25, 93 (2002); Cassidy, K.C. et al.: J. Pharmac. Biomed. Anal., 22, 869 (2000);<br></p>Formula:C5H4Cl2N2Color and Shape:NeatMolecular weight:163.0(4-(3-Methoxypropoxy)-3-methylpyridin-2-yl)methanol Hydrochloride
CAS:Controlled ProductFormula:C11H17NO3·HClColor and Shape:NeatMolecular weight:211.26 + 36.46S-[5-Chloro-3-(trifluoromethyl)pyrid-2-yl]-S-methylsulfilimine 2,4,6-trimethylbenzenesulfonate
CAS:Formula:C16H18ClF3N2O3S2Purity:95.0%Molecular weight:442.93-Mercapto-2-methylpropanoic Acid
CAS:Controlled Product<p>Impurity Captopril EP Impurity C<br>Applications 3-Mercapto-2-methylpropanoic Acid (Captopril EP Impurity C) is a useful synthetic intermediate.<br>References Lewis, S.N. et al.: J. Het. Chem., 8, 571-580 (1971)<br></p>Formula:C4H8O2SColor and Shape:NeatMolecular weight:120.17Desamino Chloroimiquimod
CAS:Controlled Product<p>Impurity Imiquimod USP Related Compound C<br>Applications Desamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.<br>References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998); Gerster, J. et al.: J. Med. Chem., 48, 3481 (2005);<br></p>Formula:C14H14ClN3Color and Shape:NeatMolecular weight:259.734-(4-Methylpiperidin-4-yl)morpholinedihydrochloride
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:257.20001220703125Methyl 6-(benzyloxy)-4-chloroquinoline-2-carboxylate
CAS:Purity:97.0%Molecular weight:327.760009765625Atrazine
CAS:<p>Applications Selective herbicide. Potential symptoms of overexposure are irritation of eyes and skin; dermatitis, skin sensitization; dyspnea, weakness, incoordination, salivation; hypothermia; liver injury.This compound is a contaminant of emerging concern (CECs)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dalgaard-Mikkelsen, S., et al.: Pharmacol. Rev., 14, 225 (1962), Muller, K., et al.: J. Environ. Qual., 31, 309 (2002), Backhaus, T., et al.: Environ. Toxicol. Chem., 23, 258 (2004),<br></p>Formula:C8H14ClN5Color and Shape:ColourlessMolecular weight:215.685-Amino-1-(5-chloro-2-pyridinyl)-1H-pyrazole-4-carbonitrile
CAS:Formula:C9H6ClN5Purity:95.0%Color and Shape:SolidMolecular weight:219.633-(3,4-Dihydro-2H-1,5-benzodioxepin-7-yl)-1-methyl-1H-pyrazole-4-carboxaldehyde
CAS:Purity:98%Molecular weight:258.2770080566406Sarafloxacin
CAS:<p>Applications Sarafloxacin is a quinolone antibiotic drug that was discontinued in 2001. Useful for biological studies and can be detected with colloidal gold test strips.<br>References Jia, F., et al.: Agric. Biotechnol., 8, 172 (2019)<br></p>Formula:C20H17F2N3O3Color and Shape:Light YellowMolecular weight:385.366-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one
CAS:Purity:98.0%Molecular weight:475.8500061035156Ref: 10-F549703
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquire(R,R)-Montelukast Bis-sulfide (~90%)
CAS:<p>Impurity Montelukast EP Impurity D; Montelukast USP Related Compound C<br>Applications (R,R)-Montelukast Bis-sulfide (Montelukast EP Impurity D; Montelukast USP Related Compound C) is an impurity of Montelukast and is a part of the diastereomer mixture Montelukast Bis-Sulfide (M567985).<br></p>Formula:C41H46ClNO5S2Purity:~90%Color and Shape:Light YellowMolecular weight:732.392-[5-chloro-2-(pyridin-4-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Purity:95.0%Molecular weight:308.2099914550781N,N-Didesmethyl Diltiazem Hydrochloride
CAS:Controlled Product<p>Applications A metabolite of Diltiazem (D460620).<br>References Sugawara, Y., et al.: J. Pharmacobio-Dynamics, 11, 211 (1988),<br></p>Formula:C20H23ClN2O4SColor and Shape:NeatMolecular weight:422.935-Imino-N,4-bis(4-phenyl)-4,5-dihydro Riluzole
Controlled ProductFormula:C16H10F6N4O2SColor and Shape:NeatMolecular weight:436.33Dehydro Norketamine-d4 (>90%)
CAS:Controlled Product<p>Applications A labelled metabolite of Ketamine (K165300).<br>References Sullivan, H., et al.: J. Med. Chem., 16, 909 (1973), Moreton, J., et al.: J. Pharmacol. Exp. Ther., 203, 303 (1977), Lin, H., et al.: J. Food Drug Anal., 13, 107 (2005),<br></p>Formula:C12H8D4ClNOPurity:>90%Color and Shape:NeatMolecular weight:225.755-(4-Trifluoromethyl-phenyl)-thiophene-2-carbaldehyde
CAS:Formula:C12H7F3OSPurity:95.0%Color and Shape:SolidMolecular weight:256.24N'-Isopropylisonicotinohydrazide phosphate
CAS:Purity:95.0%Color and Shape:Solid, solidMolecular weight:277.2170104980469Monepantel
CAS:Monepantel (AAD1566) is an organic anthelmintic and an antagonist of nAChRs from roundworms and esophageostomy.Formula:C20H13F6N3O2SPurity:99.83%Color and Shape:White PowderMolecular weight:473.394-(dimethylamino)-1-neopentylpyridin-1-ium chloride
CAS:Purity:95+%Molecular weight:228.75999450683594(±)-Albuterol-d3 (3-Hydroxymethyl-d2; α-d1)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications (±)-Albuterol-d3 (3-hydroxymethyl-d2; alpha-d1) (CAS# 1219798-60-3) is a useful isotopically labeled research compound.<br></p>Formula:C132H3H18NO3Color and Shape:Off-WhiteMolecular weight:242.33Regorafenib
CAS:Controlled Product<p>Applications It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. Dual action VEGFR & Raf inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000),<br></p>Formula:C21H15ClF4N4O3Color and Shape:Off White PowderMolecular weight:482.822-(2-Chloro-phenoxymethyl)-2 H -pyrazole-3-carboxylic acid
CAS:Formula:C11H9ClN2O3Color and Shape:SolidMolecular weight:252.65Hydroxy Flutamide
CAS:Controlled Product<p>Applications The active metabolite of the widely used non-steroidal antagonist Flutamide (F598850). Shown to be an antianhydrogen.<br>References Katchen, B., et al.: J. Clin. Endocrinol. Metab., 41, 373 (1975), Fau, D., et al.: J. Pharmacol. Exp. Ther., 269, 954 (1994), Anzenbacher, P., et al.: Drug Metab. Dispos., 30, 100 (2002), Norlin, M., et al.: J. Lipid Res., 43, 721 (2002),<br></p>Formula:C11H11F3N2O4Color and Shape:Off White SolidMolecular weight:292.211,1’-N-[Methylenebis(sulphanediylethylene)]bis(N’-methyl-2-nitroethene-1,1-diamine
CAS:Controlled Product<p>Impurity Ranitidine EP Impurity J<br>Applications 1,1’-N-[Methylenebis(sulphanediylethylene)]bis(N’-methyl-2-nitroethene-1,1-diamine (Ranitidine EP Impurity J) is a Ranitidine (R120000) impurity.<br></p>Formula:C11H22N6O4S2Color and Shape:Off-White To BeigeMolecular weight:366.462-Hydroxy-6-methylpyridine-3,4-dicarboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:197.145996093752-Amino-3,4-dimethylpyridine
CAS:Formula:C7H10N2Purity:98%Color and Shape:SolidMolecular weight:122.171N-Desmethyl Asenapine Hydrochloride
CAS:<p>Applications Asenapine (A788000) metabolite.<br>References Lobell, M., et al.: J. Pharm., Sci., 92, 360 (2003), Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Toulmin, A., et al.: J. Med. Chem., 51, 3720 (2008),<br></p>Formula:C16H14ClNO·ClHColor and Shape:NeatMolecular weight:308.206-Oxo-1-[4-(trifluoromethyl)benzyl]-1,6-dihydro-3-pyridinecarboxylic acid
CAS:Formula:C14H10F3NO3Color and Shape:SolidMolecular weight:297.233METHYL-1-[4-(AMINOSULFONYL)PHENYL]-5-(4-CHLOROPHENYL)-1H-PYRAZOLE-3-CARBOXYLATE
CAS:Purity:95.0%Molecular weight:391.82998657226563-(4-Ethoxy-3-methylphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde
CAS:Purity:98%Molecular weight:306.364990234375
![4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM260090.webp&w=3840&q=75)
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