Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65578 products of "Quinazoline and Quinoline Derivatives"
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Rilmenidine Phosphate
CAS:<p>Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.</p>Formula:C10H19N2O5PPurity:99.87% - ≥95%Color and Shape:SolidMolecular weight:278.24JNJ0966
CAS:<p>JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).</p>Formula:C16H16N4O2S2Purity:99.46% - 99.62%Color and Shape:SolidMolecular weight:360.45Cinitapride
CAS:<p>Cinitapride (Blaston) treats acid reflux and gastric issues, targeting 5-HT2, 5-HT1, and 5-HT4 receptors.</p>Formula:C21H30N4O4Purity:99.52%Color and Shape:SolidMolecular weight:402.49Lomerizine
CAS:<p>Lomerizine, a blocker of diphenylmethylpiperazine Ca2+ channel, is used to prevent migraines.</p>Formula:C27H30F2N2O3Color and Shape:SolidMolecular weight:468.54Firsocostat
CAS:<p>Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM).</p>Formula:C28H31N3O8SPurity:98% - 98.46%Color and Shape:SolidMolecular weight:569.63Eberconazole
CAS:<p>Eberconazole, a potent antifungal, is an imidazole derivative effective against dermatophytes. Administered topically.</p>Formula:C18H14Cl2N2Color and Shape:SolidMolecular weight:329.22Tofacitinib Citrate
CAS:<p>Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).</p>Formula:C22H28N6O8Purity:99.19% - 99.75%Color and Shape:SolidMolecular weight:504.49Aclidinium bromide
CAS:<p>Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis.</p>Formula:C26H30NO4S2·BrPurity:99.53% - 99.69%Color and Shape:SolidMolecular weight:564.55Vardenafil hydrochloride
CAS:<p>Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes</p>Formula:C23H33ClN6O4SPurity:99.76% - 99.86%Color and Shape:White To Off-White Cyrstalline SolidMolecular weight:525.06Dantrolene
CAS:<p>Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.</p>Formula:C14H10N4O5Purity:99.97%Color and Shape:Crystals From Aq DimethylformamideMolecular weight:314.25Olodaterol hydrochloride
CAS:<p>Olodaterol hydrochloride (BI-1744 HCl) is a novel, long-acting β2-adrenergic agonist that exerts its pharmacological effect by binding and activating β2-AR.</p>Formula:C21H27ClN2O5Purity:99.11%Color and Shape:SolidMolecular weight:422.9T-5224
CAS:<p>T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription</p>Formula:C29H27NO8Purity:97.88% - 99.29%Color and Shape:SolidMolecular weight:517.53Mosapride Citrate
CAS:<p>Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.</p>Formula:C21H25ClFN3O3·C6H8O7Purity:99.70%Color and Shape:White PowderMolecular weight:614.02Tacrine
CAS:<p>Tacrine (CS 12602) is an indirect cholinergic agonist and centrally acting anticholinesterase. It is approved for the treatment of Alzheimer's disease.</p>Formula:C13H14N2Purity:99.97%Color and Shape:SolidMolecular weight:198.26Maprotiline
CAS:<p>Maprotiline blocks norepinephrine uptake, has antidepressant properties, and fights cancer by inducing apoptosis and inhibiting ERK and CRABP1.</p>Formula:C20H23NColor and Shape:SolidMolecular weight:277.4Palbociclib monohydrochloride
CAS:<p>Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases</p>Formula:C24H29N7O2·HClPurity:99.73% - >99.99%Color and Shape:SolidMolecular weight:483.99Stiripentol
CAS:<p>Stiripentol (BCX2600) (STP) is an anticonvulsant agent, which can inhibit N-demethylation of CLB to NCLB mediated by CYP3A4 (noncompetitively) and CYP2C19 (</p>Formula:C14H18O3Purity:99.87% - >99.99%Color and Shape:White SolidMolecular weight:234.29Barnidipine hydrochloride
CAS:<p>Barnidipine HCl is a potent dihydropyridine Ca²⁺ blocker with 0.35 nM IC50 in pig coronary artery.</p>Formula:C27H30ClN3O6Purity:99.88%Color and Shape:SolidMolecular weight:528Palbociclib Isethionate
CAS:<p>Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂，IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。</p>Formula:C24H29N7O2·C2H6O4SPurity:99.01% - 99.27%Color and Shape:SolidMolecular weight:573.66Nor-benzetimide
CAS:<p>Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.</p>Formula:C16H20N2O2Purity:98.63%Color and Shape:SolidMolecular weight:272.34Elvitegravir
CAS:<p>Elvitegravir (JTK-303) is an HIV integrase inhibitor and CYP2C9 inducer.</p>Formula:C23H23ClFNO5Purity:98.43% - 99.57%Color and Shape:SolidMolecular weight:447.88Apalutamide
CAS:<p>Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.</p>Formula:C21H15F4N5O2SPurity:99.03% - 99.91%Color and Shape:SolidMolecular weight:477.43SM-7368
CAS:<p>The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.</p>Formula:C10H5ClN4O5SPurity:99.64%Color and Shape:SolidMolecular weight:328.69
