Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65644 products of "Quinazoline and Quinoline Derivatives"
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Etomidate-D5
CAS:Controlled Product<p>Applications A labelled isotope of Etomidate (E933300) which is used in neuroprotective products.<br>References Goetz, E., et al.: Anaesthesist, 23, 331 (1974), Chang, Z. L., et al.: Anal. Profiles Drug Subs., 12, 191 (1983),<br></p>Formula:C14D5H11N2O2Color and Shape:NeatMolecular weight:249.32N-Octyl Nortadalafil
CAS:Controlled Product<p>Applications Tadalafil (T004500) analog which is a phosphodiesterase 5 inhibitor.<br>References Jiru, M., et al.: J. Pharm. Biomed. Anal., 164, 713-724 (2019)<br></p>Formula:C29H33N3O4Color and Shape:White To Off-WhiteMolecular weight:487.595-Morpholinopyridin-3-amine trihydrochloride
CAS:Color and Shape:SolidMolecular weight:288.6000061035156Anastrozole Monoamide
CAS:<p>Impurity Anastrozole Monoamide Impurity<br>Applications Anastrozole Monoamide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Formula:C17H21N5OColor and Shape:WhiteMolecular weight:311.388-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
CAS:Controlled Product<p>Impurity Loratadine EP Impurity B; Loratadine USP Related Compound C<br>Applications 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one (Loratadine EP Impurity B; Loratadine USP Related Compound C) is a Loratadine intermediate. Loratidine impurity C.<br>References Cox, A., et al.: Drugs, 61, 723 (2001), Caponigro, F., et al.: Anti-Cancer Drugs, 13, 891 (2002), , Haluska, P., et al.: Eur. J. Cancer, 38, 1685 (2002),<br></p>Formula:C14H10ClNOColor and Shape:Light YellowMolecular weight:243.694-(5-(3-Hydroxyphenyl)thiophen-2-yl)-2-methylphenol
CAS:Purity:95.0%Molecular weight:282.35998535156254-(2-Keto-1-benzimidazolinyl)piperidine
CAS:Controlled Product<p>Applications 4-(2-Keto-1-benzimidazolinyl)piperidine is an impurity of Pimozide (P447800). Pimozide impurity A.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Andersson, L., et al.: J. Lipid Res., 36, 1392 (1995), Andersson, M., et al.: J. Biol. Chem., 2005, 280, 27578 (2005),<br></p>Formula:C12H15N3OColor and Shape:WhiteMolecular weight:217.27Sodium Borohydride
CAS:<p>Applications Sodium Borohydride is used as a reagent in the reduction of amino acids and their derivatives. Also used in the catalysis of ammonia borane dehydrogenation.<br> E0<br>References McKennon, M. et al.: J. Org. Chem., 58, 3568 (1993); Denney, M. et al.: J. Am. Chem. Soc., 128, 12048 (2006);<br></p>Formula:BH4NaColor and Shape:White To Off-WhiteMolecular weight:37.83Riociguat-13C-d3
CAS:Controlled Product<p>Applications Riociguat-13C-d3 is the labelled analogue of Riociguat (R520000), which is used in the treatment for pulmonary hypertension.<br>References Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011);<br></p>Formula:C1913CH16D3FN8O2Color and Shape:NeatMolecular weight:426.43Ofloxacin-d8
CAS:Controlled Product<p>Applications Labelled fluorinated quinolone antibacterial.<br>References Monk, J.P., et al.: Drugs, 33, 346 (1987), Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990)<br></p>Formula:C182H8H12FN3O4Color and Shape:NeatMolecular weight:369.421-(5-(BENZYLOXY)PYRIDIN-2-YL)CYCLOPROPANECARBOXYLIC ACID
Purity:95.0%Molecular weight:269.29998779296875Flubendazole alcohol
CAS:Controlled Product<p>Applications Flubendazole alcohol is a metabolite of the anthelmintic Flubendazole (F418500).<br>References Meuldermans, W., et al.: Eur. J. Drug Metab. Pharmacokinet., 1, 35 (1976), Dusi, G., et al.: J. Pharmaceut. Biomed. Anal., 38, 375 (2005), Cvilink, V., et al.: Vet. Parasitol., 151, 242 (2008),<br></p>Formula:C16H14FN3O3Color and Shape:White To Off-WhiteMolecular weight:315.305-(1,3-Dioxolan-2-yl)-2-(4-nitrobenzoyl)thiophene
CAS:Purity:97.0%Molecular weight:305.29998779296875Spirodiclofen
CAS:Controlled Product<p>Applications Spirodiclofen is a tetronic acid acaricide fungicide used in controlling red mites. Spirodiclofen is used in cannabis testing kits as a component of pesticide mixes (P698240).<br>References Kramer, T., et al.: Pest. Manage. Sci., 67, 1285 (2011); Ilias, A., et al.: Crop. Protect., 42, 305 (2012); Bretschneider, T., et al.: Modern. Crop. Protect. Compounds., 3, 1108 (2012)<br></p>Formula:C21H24Cl2O4Color and Shape:White To Off-WhiteMolecular weight:411.322-(Chloromethyl)-4-methylquinazoline
CAS:Controlled Product<p>Impurity Linagliptin 2-Chloromethyl Impurity<br>Applications 2-(Chloromethyl)-4-methylquinazoline, is a building block used for the preparation of Linagliptin (L465900), and its impurities, acting as type 2 diabetes drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Formula:C10H9ClN2Color and Shape:NeatMolecular weight:192.647-Hydroxy Risperidone
CAS:Controlled ProductFormula:C23H27FN4O3Color and Shape:NeatMolecular weight:426.48O3-Desethyl Apremilast
CAS:Controlled ProductFormula:C20H20N2O7SColor and Shape:NeatMolecular weight:432.453-[4-(2,4-Bis-trifluoromethyl-phenyl)-pyridin-2-yl]-4-(2,2-dimethyl-butyryl)-4H-[1,2,4]oxadiazol-5-one
Purity:95.0%Molecular weight:473.375N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:360.210998535156252-(3,4-Dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Purity:97.0%Molecular weight:288.35998535156254'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic Acid
CAS:Controlled Product<p>Impurity Telmisartan Bromo Acid Impurity<br>Applications An impurity of Telmisartan (D294250). An intermediate in the preparation of antihypertensive agents.<br>References Sharma, M.C. et al.: Adv. Appl. Sci, Res., 1, 120 (2010); Sharma, M.C. et al.: Int. J. Adv. Pharmac. Sci., 1, 249 (2010);<br></p>Formula:C14H11BrO2Color and Shape:NeatMolecular weight:291.14Oxaprozin-d10
CAS:Controlled Product<p>Applications Oxaprozin-d10 is the labeled analogue of Oxaprozin (O845400), an anti-inflammatory drug. Oxaprozin was comparable to Aspirin (A687780).<br>References Whitehouse, M.W., et al.: Biochem. Pharmacol., 20, 2309 (1971); Janssen, F.W., et al.: Drug Metab. Dispos., 6, 465 (1978); Shriver, D.A., et al.: Toxicol. Appl. Pharmacol., 42, 75 (1977)<br></p>Formula:C18H5D10NO3Color and Shape:NeatMolecular weight:303.38C-[5-(4-Thiophen-2-yl-phenyl)-[1,3,4]oxadiazol-2-yl]-methylamine; hydrochloride
Purity:95.0%Molecular weight:293.7699890136719Alogliptin Benzoate
CAS:<p>Applications Alogliptin Benzoate is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Alogliptin Benzoate is used in the treatment of type 2 diabetes.<br>References Wang, Y., et. al.: Drugs Future, 33, 7 (2008); Lynn, F., et al.: Diabetes, 50, 1004 (2001); Trumper, A., et al.: J. Endocrinol., 174, 233 (2002); Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009)<br></p>Formula:C18H21N5O2·C7H6O2Color and Shape:NeatMolecular weight:461.515-Hydroxy Dantrolene
CAS:Controlled ProductFormula:C14H10N4O6Color and Shape:YellowMolecular weight:330.255-Amino-2-bromo-pyridine-4-carbonitrile
CAS:Purity:98+%Color and Shape:SolidMolecular weight:198.02299499511726-(4-methoxyphenyl)-3-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidine
CAS:Purity:95.0%Molecular weight:307.3699951171875Brivaracetam-d7
CAS:Controlled Product<p>Applications Brivaracetam-d7, is the labeled analogue of Brivaracetam (B677645), which is a 4-n-propyl analog of levetiracetam (L331500), and a racetam derivative with anticonvulsant properties.<br>References Rosenstiel, P., et al.:Neurotherapeutics, 4 (1), 84 (2007);<br></p>Formula:C11H13D7N2O2Color and Shape:Off White SolidMolecular weight:219.33N’-Cyano-N,N-dimethylguanidine
CAS:Controlled Product<p>Impurity Cimetidine EP Impurity G<br>Applications N-Cyano-N',N''-dimethylguanidine (Cimetidine EP Impurity G) is an impurity of Cimetidine (C441650), which acts as a competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output (1).<br>References 1. Brimblecombe, R. et al.: J. Int. Med. Res. 1975 Mar:3(2) 86-92<br></p>Formula:C4H8N4Color and Shape:NeatMolecular weight:112.13Chlorpromazine-d6 Oxalate (N,N-dimethyl-d6)
CAS:Controlled Product<p>Applications Chlorpromazine-d6 Oxalate (N,N-dimethyl-d6) (CAS# 1276197-23-9) is a useful isotopically labeled research compound.<br></p>Formula:C17D6H13ClN2S·C2H2O4Color and Shape:Off-WhiteMolecular weight:414.936-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-((1-methylpiperidin-4-yl)amino)quinazolin-7-ol (trihydrochloride)
Purity:98%Molecular weight:509.9Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS:Controlled Product<p>Applications Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is an impurity of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Nevuluri, N. et al.: Monat. fuer Chem., 148, 1477 (2017);<br></p>Formula:C22H22N4O4Color and Shape:NeatMolecular weight:406.43(R)-N-Desacryloyl N-3-Chloropropionyl Ibrutinib
CAS:<p>Applications (R)-N-Desacryloyl N-3-Propionyl Ibrutinib is an impurity of Ibrutinib (I124970), which is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.<br>References MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)<br></p>Formula:C25H25ClN6O2Color and Shape:NeatMolecular weight:476.95811-Morpholino-dibenzo[b,f][1,4]thiazepine
CAS:Controlled Product<p>Applications 11-Morpholino-dibenzo[b,f][1,4]thiazepine is part of a group of 11-(substituted-amino)dibenzo[b,f][1,4]thiazepine compounds that have analgesic and sedative properties.<br>References Schmutz, J. & Hunziker, F.: Patentschrift (Switz.), 7pp. (1969)<br></p>Formula:C17H16N2OSColor and Shape:NeatMolecular weight:296.392-Descyano-2-ethyl Formyl-tofacitinib
CAS:Controlled Product<p>Applications 2-Descyano-2-ethyl Formyl-tofacitinib is an impurity compound of Tofacitinib(C781351). Tofacitinib is a Janus kinase inhibitor for the treatment of rheumatoid arthritis.<br>References Sheiner, L., et al.: Clin. Pharmacol. Ther., 25, 358 (1979), Dayneka, N., et al.: J. Pharmacokin. Biopharm., 21, 457 (1993), Changelian, P., et al.: Science, 302, 875 (2003), Lee, H., et al.: Clin. Pharmacol. Ther., 73, 348 (2003), Hutmacher, M., et al.: J. Clin. Pharmacol., 47, 238 (2007),<br></p>Formula:C18H25N5O3Color and Shape:NeatMolecular weight:359.423Dehydro Nimodipine
CAS:Controlled Product<p>Impurity Nimodipine EP Impurity A; Nimodipine USP Related Compound A<br>Stability Light Sensitive<br>Applications Dehydro Nimodipine (Nimodipine EP Impurity A; Nimodipine USP Related Compound A) is the dehydrogenated analogue and the major metabolite of the calcium channel blocker Nimodipine (N478200).<br>References Scherling, D. et al.: Arzneim.-Forsch., 41, 392 (1991); Liu, X. et al.: Yaox. Xueb., 35, 257 (2000); Eicher, H. et al.: Arch. Gerontol. Geriat., 14, 309 (1992);<br></p>Formula:C21H24N2O7Color and Shape:Light YellowMolecular weight:416.42aR-Brivaracetam
CAS:Controlled Product<p>Applications αR-Brivaracetam acts as a reagent for the preparation of 2-Oxo-1-pyrrolidine derivatives and their anticonvulsants activity. Also, is an impurity of Brivaracetam (B677645), a 4-n-propyl analog of levetiracetam (L331500), and a racetam derivative with anticonvulsant properties.<br>References Differding, E., et al.: PCT Int. Appl. (2001), WO 2001062726 A2 20010830; Rosenstiel, P., et al.:Neurotherapeutics, 4 (1), 84 (2007); Malawska, B., et al.:, Curr. Opin. Investig. Drugs, 6(7), 740 (2005);<br></p>Formula:C11H20N2O2Color and Shape:NeatMolecular weight:212.29Stiripentol
CAS:Controlled Product<p>Applications An epilepsy drug. It has been used as co-therapy for treatment of epilepsy. It inhibits the enzymes responsible for metabolism of other anti-convulsant agents.<br>References Laurie, D., et al.: J. Neurosci., 12, 4151 (1992), Smith, A., et al.: J. Pharmacol. Exp. Therap., 311, 601 (2004), Trojnar, M., et al.: Pharm. Rep., 57, 154 (2005), Drafts, B., et al.: J. Pharm. Exp. Ther., 318, 1094 (2006), Picton, A., et al.: Brain Res., 1165, 40 (2007),<br></p>Formula:C14H18O3Color and Shape:Light Yellow SolidMolecular weight:234.29Mitotane-13C6
CAS:Controlled Product<p>Applications Mitotane-13C6 is the isotope labelled analogue of Mitotane (M372500), an antineoplastic and adrenolytic agent.<br>References Das, S., and Thomas, P.: Endocrinology, 140, 1953 (1999), Andersen, A., et al.: Ther. Drug. Monit., 21, 355 (1999), Leblond, V.S., and Hontela, T.: Toxicol. Appl. Pharmacol., 157, 16 (1999)<br></p>Formula:C6C8H10Cl4Color and Shape:Light YellowMolecular weight:326.0Methyl 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)benzoate
CAS:Purity:95.0%Molecular weight:356.385009765625Levetiracetam-d3
CAS:Controlled ProductFormula:C8H11D3N2O2Color and Shape:White To Off-WhiteMolecular weight:173.23
![8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC365245.webp&w=3840&q=75)
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![C-[5-(4-Thiophen-2-yl-phenyl)-[1,3,4]oxadiazol-2-yl]-methylamine; hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF545631.webp&w=3840&q=75)
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