Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65578 products of "Quinazoline and Quinoline Derivatives"
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N-Nitroso-N-methyl-4-aminobutyric Acid (200 μg/mL in Methanol)
CAS:Formula:C5H10N2O3Color and Shape:ColourlessMolecular weight:146.14Ramifenazone
CAS:<p>Applications Analgesic, antipyretic, anti-inflammatory.<br>References Tubaro, E., et al.: Arzneim.-Forsch., 20, 1024 (1970),<br></p>Formula:C14H19N3OColor and Shape:NeatMolecular weight:245.325-(Aminosulfonyl)-2-methoxy-benzoic Acid Methyl Ester
CAS:<p>Impurity Sulpiride EP impurity B<br>Applications A reactant used in the preparation of many pharmaceutical compounds used as anticoagulants, HCV NS5B polymerase inhibitors, therapeutic drugs for treatment of neurodegenerative diseases and oral hypoglycemic agents.<br></p>Formula:C9H11NO5SColor and Shape:White To Off-WhiteMolecular weight:245.25Sitagliptin Triazecine Analog
CAS:Controlled Product<p>Impurity Sitagliptin Tablets EP Impurity FP-B<br>Applications Sitagliptin Triazecine Analog is related to the family of Sitagliptin compounds which has recently been approved for the therapy of type II diabetes.<br>References Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005), Bergman, A., et al: Clin. Ther. 28, 55 (2006)<br></p>Formula:C16H13F6N5O2Color and Shape:NeatMolecular weight:421.30Quinoxaline-2-carbonyl chloride
CAS:Purity:95.0%Color and Shape:Solid, No data available.Molecular weight:192.600006103515624-(methylthio)-N-(pyridin-3-ylmethyl)benzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:287.39999389648445-(Pyridin-2-yl)thiophene-2-carbaldehyde
CAS:Formula:C10H7NOSPurity:97.0%Color and Shape:SolidMolecular weight:189.23Methyl-1-naphthalenemethylamine
CAS:<p>Impurity Terbinafine EP Impurity A; Terbinafine BP Impurity A; Terbinafine USP Related Compound A<br>Applications Terbinafine EP Impurity A. Terbinafine BP Impurity A. Terbinafine USP Related Compound A<br></p>Formula:C12H13NColor and Shape:OrangeMolecular weight:171.241,2,3,4-Tetrahydro-2-[2-(4-hydroxyphenyl)-1-methylethyl]-4,6,8-isoquinolinetriol
CAS:Controlled ProductFormula:C18H21NO4Color and Shape:NeatMolecular weight:315.36rac Mepindolol
CAS:Controlled Product<p>Applications Mepindolol is a non-selective β-adrenoceptor blocking agent. Mepindolol is used in the treatment of glaucoma.<br>References Luque Otero, M. et al.: Br. J. Clin. Pharmacol., 17, 361 (1984); Beckmann, R. et al.: Arzneim.-Forsch., 36, 811 (1986);<br></p>Formula:C15H22N2O2Color and Shape:NeatMolecular weight:262.353',4'-Dihydroxyacetophenone
CAS:Controlled Product<p>Applications 3',4'-Dihydroxyacetophenone is an active constituent of Chinese medicine and also has antimelanogenic actiivity.<br>References Kim. Y., et al.: Biosci., Biotech., Biochem., 70, 532 (2006); Yang, D., et al.: Prostaglandins, 38, 497 (1989)<br></p>Formula:C8H8O3Color and Shape:NeatMolecular weight:152.151-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl] Aripiprazole
CAS:<p>Impurity Aripiprazole Impurity 4<br>Applications 1-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl] Aripiprazole is a synthetic impurity of the drug aripiprazole (A771000). Aripiprazole is a novel atypical antipsychotic drug used in the treatment of schizophrenia. Aripiprazole Impurity 4<br>References Filijovic, N. D., et al.: Acta Chromatogr., 26, 13 (2014)<br></p>Formula:C36H42Cl2N4O4Color and Shape:White To Off-WhiteMolecular weight:665.649Captopril
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Orally active angiotensin-converting enzyme (ACE) inhibitor. Neuroprotective & Neuroresearch Product.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978),<br></p>Formula:C9H15NO3SColor and Shape:NeatMolecular weight:217.29Captopril-d3
CAS:Controlled Product<p>Applications Orally active angiotensin-converting enzyme (ACE) inhibitor.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978),<br></p>Formula:C9D3H12NO3SColor and Shape:White SolidMolecular weight:220.30rac-Monepantel Sulfone
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications rac-Monepantel Sulfone is a derivative of Monepantel (M515800), a recently discovered anthelmitic used in the treatment of parasitic nematodes via stun or kill without damaging the host entity.<br>References Baur, R. et al.: Mol. Pharm., 87, 96 (2015); Stuchlikova, L. et al.: Chemico. Biol. Interact., 227, 63 (2015);<br></p>Formula:C20H13F6N3O4SColor and Shape:NeatMolecular weight:505.39Pyraclostrobin
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Pyraclostrobin is a fungicide for use in seed grass and food crops. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gyldenkaerne, S., et al.: Pestic Sci., 55, 1210 (1999), Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007),<br></p>Formula:C19H18ClN3O4Color and Shape:YellowMolecular weight:387.822-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzamide
CAS:Purity:95.0%Molecular weight:297.289001464843755-amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile
CAS:Purity:97%Molecular weight:262.70001220703125Tianeptine-d12
CAS:Controlled Product<p>Applications Labelled tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant.<br>References Malen, C., et al.: Experientia, 28, 811 (1972), Safa, A., et al.: J. Biol. Chem., 262, 7884 (1987), Ford, J.M., et al.: Pharmacol. Rev., 42, 155, (1990), Pierre, A., et a.: Cancer Res., 51, 2312 (1991),<br></p>Formula:C21H13D12ClN2O4SColor and Shape:NeatMolecular weight:449.031-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid
CAS:Formula:C25H24N4O5Color and Shape:Light Orange ColourMolecular weight:460.48Desmethyl Levofloxacin Hydrochloride
CAS:Controlled Product<p>Applications A metabolite of Levofloxacin.<br>References Sudo, K., et al.: Xenobiotica, 16, 72 (1986), Wong, F., et al.: Drug Metab. Dispos., 18, 1103 (1990), Aminimanizani, A., et al.: J. Clin. Pharmacokinet., 40, 169 (2001), Athamna, A., et al.: J. Antimicrob. Chemother., 53, 247 (2004), Tanaka, M., et al.: J. Pharmacol., 56, 463 (2004),<br></p>Formula:C17H18FN3O4•HClColor and Shape:NeatMolecular weight:347.343646Zomepirac Acyl-O-β-D-glucuronide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An unstable metabolite of the nonsteroidal anti-inflammatory drug (NSAID) Zomepirac (Z675000) that is capable of reacting with endogenous proteins to form potentially toxic covalent ZP-protein adducts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References King, A.R. et al.: J. Phamacol. Toxicol. Meth., 36, 131 (1996); Olsen, J. et al.: Chem. Res. Toxicol., 18, 1729 (2005); O’Neill, P.J. et al.: J. Clin. Pharmacol., 22, 470 (1982);<br></p>Formula:C21H22ClNO9Color and Shape:BeigeMolecular weight:467.85O-Desmethyl Astemizole
CAS:Controlled Product<p>Applications A metabolite of Astemizole.<br>References Nagata, K., et al.: J. Biol. Chem., 268, 24720 (1993), Benton, R., et al.: Clin. Pharmacol. Ther., 59, 383 (1996), Hashizume, T., et al.: Drug Metab. Dispos., 26, 566 (1998), Scarborough, P., et al.: Drug Metab. Rev., 31, 205 (1999),<br></p>Formula:C27H29FN4O·ClHColor and Shape:NeatMolecular weight:481.001-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:Purity:95.0%Molecular weight:309.32101440429693-Desamino-3,4-dehydro Sitagliptin
CAS:<p>Impurity Sitagliptin Tablets EP Impurity FP-C<br>Applications 3-Desamino-3,4-dehydro Sitagliptin is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.<br>References Kim, D., et al.: J. Med. Chem. 48, 141 (2005); Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005); Bergman, A., et al: Clin. Ther. 28, 55 (2006)<br></p>Formula:C16H12F6N4OColor and Shape:White To Off-WhiteMolecular weight:390.28Dothiepin-d3
CAS:Controlled Product<p>Stability Temperature Sensitive<br>Applications Labelled Dothiepin (D536500). A tricyclic antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Metysova, J., et al.: Arzneim.-Forsch., 13, 1039 (1963), Maguire, K.P., et al.: Br. J. Clin. Pharmacol., 12, 405 (1981), Donovan, S., et al.: Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 18, 1143 (1994),<br></p>Formula:C19H18D3NSColor and Shape:NeatMolecular weight:298.46rac Efavirenz
CAS:<p>Applications rac Efavirenz is a mixture of both enantiomers for Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.<br>References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995); Hadaruga, D. et al.: J. Med Chem., 48, 2432 (2005);<br></p>Formula:C14H9ClF3NO2Color and Shape:NeatMolecular weight:315.682-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid
CAS:Purity:97%Molecular weight:313.7399902343753-IODO-5-(PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDINE
CAS:Purity:95.0%Molecular weight:322.1090087890625(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide
CAS:Controlled Product<p>Applications (S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide is used in the synthesis of Vildagliptin (V305000), an oral anti-diabetic drug, and its impurities (H971380) (Impurity A).<br>References Kumar, N., et al.: J. Pharmaceut. Biomed.,119, 114 (2016); Deng, Y., et al.: Lett. Org. Chem., 11, 780 (2014);<br></p>Formula:C7H11ClN2O2Color and Shape:NeatMolecular weight:190.63(S)-(-)-Dropropizine N,N-Dioxide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications (S)-(-)-Dropropizine N,N-Dioxide, is an impurity of (S)-(-)-Dropropizine (D681500), S-Form of Dropropizine. Cough suppressive phenylpiperazine derivative. Antitussive.<br>References Bakken, G., et al.: J. Med. Chem., 43, 4534 (2000), Salunkhe, M., et al.: Enz. Microb. Technol., 28, 333 (2001), Atul, B., et al.: J. Pharm. Sci., 91, 2067 (2002),<br></p>Formula:C13H20N2O4Color and Shape:NeatMolecular weight:268.31Nilotinib N-Oxide
CAS:Controlled Product<p>Applications A metabolite of Nilotinib (N465300). It is a COVID19-related research product.<br></p>Formula:C28H22F3N7O2Color and Shape:NeatMolecular weight:545.52Tolmetine
CAS:Controlled Product<p>Applications 1-Methyl-5-p-toluoylpyrrole-2-acetic acid (cas# 26171-23-3) is a useful research chemical.<br></p>Formula:C15H15NO3Color and Shape:NeatMolecular weight:257.28
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