Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65573 products of "Quinazoline and Quinoline Derivatives"
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4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Hydrochloride
CAS:Controlled ProductFormula:C14H17N3O4·ClHColor and Shape:NeatMolecular weight:327.761,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one
CAS:Controlled Product<p>Impurity Ondansetron EP Impurity D; Ondansetron USP Related Compound D<br>Applications 1,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one (Ondansetron EP Impurity D; Ondansetron USP Related Compound D) is an impurity of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feng, R. et al.: Zhong. Yaox. Zaz., 46, 1436 (2011); Zizkovsky, V. et al.: J. Pharm. Biomed. Anal., 44, 1048 (2007)<br></p>Formula:C14H13NOColor and Shape:WhiteMolecular weight:211.26rac Ramelteon-d3
CAS:Controlled Product<p>Applications Melatonin MT1/MT2 receptor agonist. Sedative, hypnotic.<br>References Yukuhiro, N., et al.: Brain Res., 59, 1027 (2004), Cajochen, C., et al.: Curr. Opin. Invest. Drugs, 6, 114 (2005), Kato, K., et al.: Neuropharmacology, 48, 301 (2005),<br></p>Formula:C16H18D3NO2Color and Shape:NeatMolecular weight:262.361?-Hydroxy Bufuralol-d9 (Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Bufuralol, a β-Adrenergic blocker with peripheral vasodilating activity.<br>References Boobis, A.R., et al.: Biochem. Pharmacol., 34, 65 (1985), Yamazaki, H., et al.: Mol. Pharmacol., 46, 568 (1994), Mast, N., et al.: Biochem., 42, 14284 (2003),<br></p>Formula:C16H14D9NO3Color and Shape:White To YellowMolecular weight:286.41N-Benzyl Carvedilol
CAS:Controlled Product<p>Impurity Carvedilol EP Impurity C; Carvedilol Impurity C; Carvedilol USP C<br>Applications N-Benzyl Carvedilol (Carvedilol EP Impurity C) is an impurity of Carvedilol (C184625) and a degradation product in Carvedilol tablets.<br>References Karle, C., et al.: Cardiovasc. Res., 49, 361 (2001), Chen, J., et al.: Acta Cardiol. Sin., 19, 93 (2003), Xiang, T., et al.: Pharm. Res., 22, 1205 (2005),<br></p>Formula:C31H32N2O4Color and Shape:NeatMolecular weight:496.60Gefitinib Morpholine N-oxide
CAS:Controlled Product<p>Applications Gefitinib Morpholine N-oxide is the N-oxide derivative of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).<br>References Lynch, T.J., et al.: N. Engl. J. Med., 350, 2129 (2004); Engelman, J.A., et al.: Science, 316, 1039 (2007); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003)<br></p>Formula:C22H24ClFN4O4Color and Shape:White To Off-WhiteMolecular weight:462.902-(3-Pyridyl)-2-oxazoline
CAS:Controlled Product<p>Applications 2-(3-Pyridyl)-2-oxazoline is an impurity of Nicorandil (N398500). Nicorandil impurity E.<br></p>Formula:C8H8N2OColor and Shape:Off-White To Light YellowMolecular weight:148.16N-Benzyl Salbutamon Hydrochloride
CAS:Controlled Product<p>Applications N-Benzyl Salbutamon Hydrochloride is an impurity of Albuterol (Salbutamol) (A514500), an β2-adrenoceptor agonist. Bronchodilator; tocolytic.<br>References 1. Collin, D. et al.: J. Med. Chem. 1970 Jul;13(4):674-80.2. Raidal, S. et al.: Vet. J. 2017 Apr;222:22-28.<br></p>Formula:C20H25NO3·ClHColor and Shape:NeatMolecular weight:363.882-Acetoxy-N-(2-thiazolyl)benzamide
CAS:Controlled Product<p>Applications 2-Acetoxy-N-(2-thiazolyl)-benzamide is used in the synthesis of thiazolides as novel antiviral agents. Used in the inhibition of hepatitis C virus replication. Nitazoxanide Impurity<br>References Edwards, G. et al.: J. Med. Chem., 54, 8670 (2011);<br></p>Formula:C12H10N2O3SColor and Shape:Off-WhiteMolecular weight:262.281-(2-Methoxyphenyl)piperazine
CAS:Controlled Product<p>Applications A piperazine derivative and a selective antagonist at D3 receptors that influences the expression of cocaine-induced conditioned place preference (CPP).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Byrska, B. et al.: Zagadnien Nauk Sadowych 81, 101 (2010); Cervo, L. et al.: Pharmacol Biochem Be 82, 727 (2005)<br></p>Formula:C11H16N2OColor and Shape:NeatMolecular weight:192.262-Mercapto-N-methyl-benzamide
CAS:Controlled Product<p>Stability Air Sensitive<br>Applications 2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib (A794650) which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.<br>References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),<br></p>Formula:C8H9NOSColor and Shape:BeigeMolecular weight:167.228(2,6-Dichloro-phenyl)guanidine
CAS:Controlled ProductFormula:C7H7Cl2N3Color and Shape:NeatMolecular weight:204.0571,5-Dihydroxyempagliflozin
CAS:Controlled ProductFormula:C23H29ClO8Color and Shape:NeatMolecular weight:468.92Norketamine-d4
CAS:Controlled Product<p>Applications A labelled metabolite of Ketamine (K165300).<br>References Sullivan, H., et al.: J. Med. Chem., 16, 909 (1973), Moreton, J., et al.: J. Pharmacol. Exp. Ther., 203, 303 (1977), Lin, H., et al.: J. Food Drug Anal., 13, 107 (2005),<br></p>Formula:C12H10D4ClNOColor and Shape:NeatMolecular weight:227.72Edoxaban Tosylate Monohydrate
CAS:<p>Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Formula:C31H38ClN7O7S2•xH2OColor and Shape:White To Off-WhiteMolecular weight:720.26(R)-3-Aminopiperidine Dihydrochloride
CAS:Controlled Product<p>Applications (R)-3-Aminopiperidine Dihydrochloride has been used as a reactant for the preparation of dipeptidyl peptidase IV inhibitors derived from Alogliptin.<br>References Xie, Hui., et. al.: Eur. J. Med. Chem., 68, 312 (2013)<br></p>Formula:C5H14Cl2N2Color and Shape:NeatMolecular weight:173.08Deferiprone-d3
CAS:Controlled Product<p>Applications A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transferrin and ferritin in vitro.<br>References Kontoghiorghes, G.J.: Lancet I, 817 (1985), Kontoghiorghes, G.J., et al.: Br. J. Haematol., 62, 607 (1986), Kontoghiorghes, G.J., et al.: Biochem. Biophys. Acta, 869, 141 (1986), Kontoghiorghes, G.J., et al.: Arzneim.-Forsch., 37, 1099 (1987),<br></p>Formula:C7H6D3NO2Color and Shape:White To Off-WhiteMolecular weight:142.172,6-Dimethylaniline-d6
CAS:Controlled Product<p>Applications Labelled Bupivacaine (B689560) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lepage, F., et al.: Eur. J. Med. Chem., 27, 581 (1992), Thummel, K.E., et al.: Drug Metab. Dispos., 21, 350 (1993)<br></p>Formula:C82H6H5NColor and Shape:BrownMolecular weight:127.22rac N-Propyl-2-cyanimidopyrrolidine-5-acetic Acid
CAS:Controlled Product<p>Applications rac N-Propyl-2-cyanimidopyrrolidine-5-acetic Acid is a potent peptidic renin inhibitor. Pramipexole Related Compound<br></p>Formula:C10H15N3O2Color and Shape:NeatMolecular weight:209.24Lansoprazole-d4
CAS:Controlled ProductFormula:C162H4H10F3N3O2SColor and Shape:NeatMolecular weight:373.39Dipyridamole Tri(diethanolamine)
CAS:Controlled Product<p>Impurity Dipyridamole EP Impurity B<br>Applications Dipyridamole Tri(diethanolamine) (Dipyridamole EP Impurity B) Dipyridamole (D492625) impurity.<br>References Gerlach, E., et al.: Arzneim.-Forsch., 15, 558 (1965),<br></p>Formula:C23H40N8O6Color and Shape:NeatMolecular weight:524.61Sulindac Sulfide
CAS:<p>Stability Hygroscopic<br>Applications An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP.<br>References Hermann, C., et al.: Oncogene, 17, 1769 (1998), Lim, T.J., et al.: Biochem. Pharmacol., 58, 1097 (1999), Zhang, Z. and DuBois, R.N.: Gastroenterology, 118, 1012 (2000),<br></p>Formula:C20H17FO2SColor and Shape:Yellow-OrangeMolecular weight:340.41(Z)-Flunarizine
CAS:Controlled Product<p>Impurity Flunarizine EP Impurity D<br>Applications (Z)-Flunarizine is Z-isomer of Flunarizine(F455200, Dihydrochloride), which is a calcium channel blocker. Flunarizine is a fluorinated derivative of Cinnarizine and a vasodilator (cerebral and peripheral). EP Impurity C<br>References Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975), Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979), Nihard, P., et al.: Angiology, 33, 37 (1982), Holmes, B., et al.: Drugs, 27, 6 (1984),<br></p>Formula:C26H26F2N2Color and Shape:NeatMolecular weight:404.49N-Desmethyl Riociguat
CAS:Controlled Product<p>Applications N-Desmethyl-riociguat, is a complex that is part affiliated with potent oral stimulator for the treatment of pulmonary hypertension.<br>References Mittendorf, J., et al.: ChemMedChem., 4, 853 (2009)<br></p>Formula:C19H17FN8O2Color and Shape:NeatMolecular weight:408.39Brexpiprazole S-Oxide
CAS:<p>Applications Brexpiprazole S-Oxide is an impurity and potential metabolite of Brexpiprazole (B677385), a drug candidate useful in treatment and prevention of mental disorders including CNS disorders.<br>References Yamashita, H., et al.: PCT Int. Appl., WO 2006112464 A1 20061026 (2006);<br></p>Formula:C25H27N3O3SColor and Shape:NeatMolecular weight:449.565Hydroxymethyl Ivacaftor
CAS:Controlled Product<p>Applications Hydroxymethyl Ivacaftor is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.<br>References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)<br></p>Formula:C24H28N2O4Color and Shape:NeatMolecular weight:408.49(S,S)Dinitroso Ethambutol
CAS:Controlled ProductFormula:C10H22N4O4Color and Shape:WhiteMolecular weight:262.311-[3-(Dimethylamino)propyl]-3-ethylurea
CAS:Controlled Product<p>Applications 1-[3-(Dimethylamino)propyl]-3-ethylurea is a reagent used in the preparation of water soluble, multifunctional antibody-porphyrin gold nanoparticles.<br>References Penon, O. et al.: J. Colloid. Inter. Sci., 496, 100 (2017);<br></p>Formula:C8H19N3OColor and Shape:NeatMolecular weight:173.26Cathine Hydrochloride
CAS:Controlled ProductFormula:C9H13NO·ClHColor and Shape:Off-WhiteMolecular weight:187.67(R)-Praziquantel
CAS:Controlled ProductFormula:C19H24N2O2Color and Shape:White To Light YellowMolecular weight:312.413,4-Dihydro-7-(4-hydroxybutoxy)-2(1H)-quinolinone
CAS:Formula:C13H17NO3Color and Shape:NeatMolecular weight:235.28Empagliflozin α-Anomer
CAS:Controlled ProductFormula:C23H27ClO7Color and Shape:White To Off-WhiteMolecular weight:450.9092-[-2[(5-Nitro-2-furanyl)methylene]hydrazinyl]acetic Acid
CAS:Controlled Product<p>Applications 2-[-2[(5-Nitro-2-furanyl)methylene]hydrazinyl]acetic Acid is an impurity of Nitrofurantoin (N493850), a nitrofuran antibiotic with low resistance potential that is rapidly metabolized by mammals.<br>References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976); Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004);<br></p>Formula:C7H7N3O5Color and Shape:NeatMolecular weight:213.1483-Hydroxyagomelatine
CAS:<p>Impurity Agomelatine Impurity 11/ Agomelatine 3-Hydroxy Impurity<br>Applications 3-Hydroxyagomelatine is an intermediate in the synthesis of 1-(aminoethyl)naphthalene derivative with potential binding affinity for melatonin receptors. Agomelatine Impurity 11<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simonin, G., et al.: J. Pharma. Biomed. Anal., 21, 591 (1999)<br></p>Formula:C15H17NO3Color and Shape:NeatMolecular weight:259.3(S)-5-Iodo Naproxen
CAS:Controlled ProductFormula:C14H13IO3Color and Shape:NeatMolecular weight:356.16N1-Ethylcarbamoyl Cabergoline (>90%)
CAS:Formula:C29H42N6O3Color and Shape:Off White SolidMolecular weight:522.68Baricitinib
CAS:Controlled Product<p>Applications Baricitinib is a JAK1 and JAK2 inhibitor and have been used as a promising treatment for rheumatoid arthritis.<br>References Greenwald, L.J., et al.: Int. J. Clin. Rheumatol., 6, 401 (2011); Fridman, J.S., et al.: J. Immunol., 184, 5298 (2010);<br></p>Formula:C16H17N7O2SColor and Shape:White SolidMolecular weight:371.42rac-Epinephrine-3-O-sulfate
CAS:Formula:C9H13NO6SColor and Shape:White To Off-WhiteMolecular weight:263.268Rebamipide 3-Chloro Impurity (>80%)
CAS:Controlled Product<p>Applications Rebamipide 3-Chloro Impurity (CAS# 90098-05-8) is a useful research chemical compound.<br></p>Formula:C19H15ClN2O4Purity:>80%Color and Shape:White To Off-WhiteMolecular weight:370.7864
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