Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65580 products of "Quinazoline and Quinoline Derivatives"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
(S)-9-Hydroxy Risperidone
CAS:Controlled Product<p>Applications The S-enantiomer metabolite of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),<br></p>Formula:C23H27FN4O3Color and Shape:NeatMolecular weight:426.48Nepafenac
CAS:<p>Applications A non-steroidal anti-inflammatory with analgesic activity; selective COX-2 inhibitor. Prodrug of Amfenac.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Walsh, D.A., et al.: J. Med. Chem., 33, 2296 (1990), Gamache, D.A., et al.: Inflammation, 24, 357 (2000), Lindstrom, R., et al.: Curr. Med. Res. Opin., 22, 397 (2006),<br></p>Formula:C15H14N2O2Color and Shape:NeatMolecular weight:254.282,6-Dimethoxypyridine-3,5-diamine hydrochloride
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:205.639999389648442-Deschloro Aripiprazole
CAS:<p>Impurity Aripiprazole EP Impurity D<br>Applications 2-Deschloro Aripiprazole (Aripiprazole EP Impurity D) is an impurity of the antipsychotic agent Aripiprazole (A771000). Aripiprazole impurity B.<br>References Akaike, A., et al.: Brain Res., 418, 262 (1987); Kikuchi, K., et al.: Life Sci., 42, 343 (1988); Caprathe, B., et al.: J. Med. Chem., 34, 2736 (1991); Yamada, S., et al.: J. Pharm. Pharmacol., 49, 206 (1997);<br></p>Formula:C23H28ClN3O2Color and Shape:WhiteMolecular weight:413.944-(5-Amino-3-methylpyrazol-1-yl)-piperidine-1-carboxylic acid tert-butyl ester
CAS:Formula:C14H24N4O2Purity:97%Color and Shape:SolidMolecular weight:280.372L-Valine Methyl Ester Hydrochloride
CAS:Controlled Product<p>Applications L-Valine Methyl Ester Hydrochloride is used in the synthesis of Valaciclovir (V085000), the L-Valine ester prodrug of Acyclovir (A192400), orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral.<br>References McClean, K. et al.: Tetrahedron Lett., 52, 215 (2011); Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979), Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988), Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992), Beauchamp, L.M., et al.: Antiviral Chem. Chemother., 3, 157 (1992), Weller, S., et al.: Clin. Pharmacol. Ther., 54, 595 (1996), Lowance, D., et al.: N. Engl. J. Med., 340, 1462 (1999),<br></p>Formula:C6H13NO2·ClHColor and Shape:NeatMolecular weight:167.633,3'-(5'-(3-(Pyridin-3-yl)phenyl)-[1,1':3',1''-terphenyl]-3,3''-diyl)dipyridine
CAS:Purity:97%Molecular weight:537.666015625Anastrozole
CAS:Controlled Product<p>Applications An aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Formula:C17H19N5Color and Shape:NeatMolecular weight:293.374-Diphenylmethoxypiperidine hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications 4-Diphenylmethoxypiperidine, HCl<br></p>Formula:C18H21NO·ClHColor and Shape:WhiteMolecular weight:303.832-(9-(Pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetonitrile
CAS:Purity:97%Color and Shape:SolidMolecular weight:256.3489990234375Eltrombopag Olamine
CAS:<p>Stability Hygroscopic<br>Applications Eltrombopag is an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008)<br></p>Formula:C25H22N4O4·2C2H7NOColor and Shape:Dark RedMolecular weight:564.63Bupivacaine
CAS:<p>Applications Bupivacaine is a sodium channel blocker, local anesthetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wilson, T.D., et al.: Anal. Profiles Drug Subs., 19, 59 (1990), McClellan, K.J., et al.: Drugs, 56, 355 (1998),<br></p>Formula:C18H28N2OColor and Shape:NeatMolecular weight:288.431-[2-(2,4-Difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole
CAS:<p>Impurity Fluconazole EP Impurity G<br>Applications 1-[2-(2,4-Difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole (Fluconazole EP Impurity G) is an epoxy impurity of the antifungal agent Fluconazole (F421000).<br>References Bourichi, H. et al.: STP Pharm. Prat., 18, 285 (2008); Dongre, V.G. et al.: J. Pharmac. Biomed. Anal., 42, 334 (2006):<br></p>Formula:C11H9F2N3OColor and Shape:NeatMolecular weight:237.21Dolutegravir-d4
CAS:Controlled Product<p>Applications Isotope labelled Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.<br>References Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011);<br></p>Formula:C20H15D4F2N3O5Purity:>80%Color and Shape:NeatMolecular weight:423.404-Pyrazol-1-ylmethyl-phenylamine; hydrochloride
CAS:Formula:C10H12ClN3Purity:95.0%Color and Shape:SolidMolecular weight:209.68((3S,4R)-4-(4-Fluorophenyl)piperidin-3-yl)methanol
CAS:Controlled Product<p>Applications ((3s,4r)-4-(4-Fluorophenyl)Piperidin-3-Yl)Methanol (cas# 125224-43-3) is a useful research chemical.<br></p>Formula:C12H16FNOColor and Shape:Light YellowMolecular weight:209.262-{[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-5,5-dimethylcyclohexane-1,3-dione
CAS:Molecular weight:404.89001464843755-Chloro-2-thiophenecarboxylic Acid
CAS:Controlled Product<p>Applications 5-Chloro-2-thiophenecarboxylic Acid is a metabolite of Rivaroxaban (R538000).<br>References Brickner, S., et al.: J. Med. Chem., 39, 673 (1996), Sato, K., et al.: Eur. J. Pharmacol., 347, 231 (1998), Chang, P., et al.: IDrugs, 7, 50 (2004), Weinz, C., et al.: Drug Metab. Dispos., 37, 1056 (2009)<br></p>Formula:C5H3ClO2SColor and Shape:NeatMolecular weight:162.59ent-Montelukast Sodium Salt
CAS:<p>Impurity Montelukast EP Impurity A<br>Applications ent-Montelukast Sodium Salt (Montelukast EP Impurity A) is the S-enantiomer of Montelukast. Results indicate that there is no apparent bioinversion of Montelukast to its S-enantiomer in humans.<br>References Cheng, H., et al.: Pharm. Res., 11, 824 (1994), Amin, R., et al.: J. Pharm. Biomed. Anal., 13, 155 (1995), Jones, T., et al.: Can. J. Physiol. Pharmacol., 73, 191 (1995), Labelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1995),<br></p>Formula:C35H35ClNO3S·NaColor and Shape:Off-White To Light YellowMolecular weight:608.17rac Albuterol
CAS:Controlled Product<p>Applications rac Albuterol is a β2-adrenoceptor agonist. Bronchodilator; tocolytic. This compound is a contaminant of emerging concern (CECs).<br>References Miyagawa, N., et al.: Biol. Pharm. Bull., 31, 2260 (2008), Gonzalez-Munoz, C., et al.: Eur. J. Pharmacol., 607, 151 (2009), Kern, C., et al.: J. Med. Chem., 52, 1773 (2009),<br></p>Formula:C13H21NO3Color and Shape:WhiteMolecular weight:239.31Semicarbazide-13C,15N2 Hydrochloride
CAS:Controlled Product<p>Applications A labelled metabolite of Nitrofuran.Environmental contaminants; Food contaminants; Heat processing contaminants<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Elliott, J., et al.: J. Pharm. Pharmacol., 41, 37 (1989), Tribalat, L., et al.: Anal. Bioanal. Chem., 386, 2168 (2006), Chu, P., et al.: J. Agric. Food Chem., 55, 2129 (2007),<br></p>Formula:CH515N2NO·ClHColor and Shape:NeatMolecular weight:114.511-[3-(Dimethylamino)propyl]-3-ethylurea
CAS:Controlled Product<p>Applications 1-[3-(Dimethylamino)propyl]-3-ethylurea is a reagent used in the preparation of water soluble, multifunctional antibody-porphyrin gold nanoparticles.<br>References Penon, O. et al.: J. Colloid. Inter. Sci., 496, 100 (2017);<br></p>Formula:C8H19N3OColor and Shape:NeatMolecular weight:173.262-[(2,4-Dimethylphenyl)sulfanyl]aniline
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 2-[(2,4-Dimethylphenyl)sulfanyl]aniline is used in the study of N-O-glucuronide metabolites of Lu AA21004 (Vortioxetine [V766000]), an antidepressant.<br>References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013); Uldam, H. et al.: Drug Metab. Disp., 39, 2264 (2011);<br></p>Formula:C14H15NSColor and Shape:Light Brown To Dark BrownMolecular weight:229.342-(2-pyridinylamino)-8-quinolinol
CAS:Purity:95.0%Color and Shape:Solid, CrystallineMolecular weight:237.26199340820312(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
CAS:Purity:95.0%Molecular weight:345.4200134277344Cathine Hydrochloride
CAS:Controlled ProductFormula:C9H13NO·ClHColor and Shape:Off-WhiteMolecular weight:187.671-(Mercaptomethyl)cyclopropaneacetic Acid
CAS:Controlled Product<p>Applications An intermediate of Montelukast.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C6H10O2SColor and Shape:NeatMolecular weight:146.21Moclobemide-d8
CAS:Controlled Product<p>Applications Moclobemide-d8 is the labeled analogue of Moclobemide (M481000), a reversible monoamine oxidase inhibitor.<br>References Wiesel, F.A., et al.: Eur. J. Clin. Pharmacol., 28, 89 (1985), Burkard, W.P., et al.: J. Pharmacol. Exp. Ther., 248, 391 (1989)<br></p>Formula:C13H9D8ClN2O2Color and Shape:Off White SolidMolecular weight:276.794,6-Bis(3,5-di(pyridin-4-yl)phenyl)-2-phenylpyrimidine
CAS:Purity:98%Molecular weight:616.728027343751-(5-Fluoropyridin-2-yl)-1,4-diazepane dihydrochloride
CAS:Purity:95.0%Molecular weight:268.1600036621094(R)-Praziquantel
CAS:Controlled ProductFormula:C19H24N2O2Color and Shape:White To Light YellowMolecular weight:312.414-(4-Methylpiperidin-4-yl)morpholinedihydrochloride
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:257.20001220703125rac-4-Hydroxy Propranolol-d7 Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A labelled metabolite of Propranolol.<br>References Walle, T., et al.: Drug Metab. Dispos., 13, 204 (1985), Mason, R., et al.: J. Med. Chem., 34, 869 (1991), Anderson, R., et al.: Biochem. Pharmacol., 52, 341 (1996), Hung, D., et al.: J. Pharmacol. Exp. Ther., 297, 780 (2001),<br></p>Formula:C16D7H14NO3·ClHColor and Shape:Light Red To BrownMolecular weight:318.856-bromo-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:320.2099914550781Clofedanol Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A centrally-acting cough suppressant. It has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.<br>References Yuizono, T., et al.: Yakugaku Zasshi, 87, 915 (1967), Nomura, A., et al.: Oyo Yakuri, 8, 119 (1974),<br></p>Formula:C17H20ClNO·ClHColor and Shape:White To Off-WhiteMolecular weight:326.26Cimetidine-d3
CAS:Controlled Product<p>Applications Competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output.<br>References Brimblecombe, R.W., et al.: J. Int. Med. Res., 3, 86 (1975),<br></p>Formula:C10D3H13N6SColor and Shape:WhiteMolecular weight:255.34
![3,3'-(5'-(3-(Pyridin-3-yl)phenyl)-[1,1':3',1''-terphenyl]-3,3''-diyl)dipyridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF609972.webp&w=3840&q=75)
![2-(9-(Pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetonitrile](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF617708.webp&w=3840&q=75)
![1-[2-(2,4-Difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD446045.webp&w=3840&q=75)
![2-{[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-5,5-dimethylcyclohexane-1,3-dione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF094194.webp&w=3840&q=75)
![1-[3-(Dimethylamino)propyl]-3-ethylurea](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD492553.webp&w=3840&q=75)
![2-[(2,4-Dimethylphenyl)sulfanyl]aniline](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD447335.webp&w=3840&q=75)
![(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF448256.webp&w=3840&q=75)
![3-(3-Phenyl-[1,2,4]oxadiazol-5-ylmethyl)-pyridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF545451.webp&w=3840&q=75)
