Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65578 products of "Quinazoline and Quinoline Derivatives"
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3-[2-(3,4-dimethoxyphenyl)ethyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one
CAS:Purity:98%Molecular weight:342.412-METHOXY-5-(5-(PYRIDIN-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PHENOL
CAS:Purity:95.0%Molecular weight:317.34799194335942-Amino-4-(4-isopropyl-phenyl)-thiophene-3-carboxylic acid amide
CAS:Formula:C14H16N2OSPurity:97%Color and Shape:SolidMolecular weight:260.36N-methoxy-N-methyl-2-phenylquinoline-4-carboxamide
CAS:Purity:95.0%Molecular weight:292.33801269531252-[5-bromo-2-(pyridin-2-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Purity:95.0%Molecular weight:352.66000366210946-Amino-4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-7-ethoxyquinoline-3-carbonitrile
CAS:Purity:98%Molecular weight:445.91000366210941-(1,3-Dimethyl-1H-pyrazol-4-yl)-4,4,4-trifluoro-butane-1,3-dione
CAS:Formula:C9H9F3N2O2Purity:98%Color and Shape:SolidMolecular weight:234.1782-((2R,3R)-3-(tert-butyl)-4-methoxy-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine
CAS:Purity:95%,99%eeMolecular weight:301.32598876953125(2S,2'S)-1,1'-[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)imino]bis(1-oxo-2,1-ethanediyl)]bis-2-pyrrolidinecarbonitrile
CAS:Formula:C24H33N5O3Color and Shape:Off-WhiteMolecular weight:439.55Safinamide Mesylate
CAS:Controlled Product<p>Applications Safinamide mesylate is a potent and selective MAO-B inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C17H19FN2O2·CH4O3SColor and Shape:White To Off-WhiteMolecular weight:398.45Telmisartan-d3
CAS:Controlled ProductFormula:C332H3H27N4O2Color and Shape:BeigeMolecular weight:517.64Dasatinib monohydrate
CAS:Controlled ProductFormula:C22H26ClN7O2S·H2OColor and Shape:White To Off-WhiteMolecular weight:506.02Brexpiprazole-d8
CAS:Controlled Product<p>Applications Isotope labelled Brexpiprazole (B677385) is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders.<br>References Yamashita, H., et al.: PCT Int. Appl., WO 2006112464 A1 20061026 (2006)<br></p>Formula:C25H19D8N3O2SColor and Shape:White To BeigeMolecular weight:441.62(S)-(-)-Thalidomide
CAS:Controlled Product<p>Applications Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative.<br>References D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)<br></p>Formula:C13H10N2O4Color and Shape:White To Off-WhiteMolecular weight:258.23Ebastine-d5
CAS:Controlled Product<p>Applications A nonsedating type histamine H1-receptor antagonist. Antihistaminic.<br>References Vincent, J., et al.: Brit. J. Clin. Pharmacol., 26, 497 (1988)<br></p>Formula:C32H34D5NO2Color and Shape:NeatMolecular weight:474.694-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Hydrochloride
CAS:Controlled ProductFormula:C14H17N3O4·ClHColor and Shape:NeatMolecular weight:327.761,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one
CAS:Controlled Product<p>Impurity Ondansetron EP Impurity D; Ondansetron USP Related Compound D<br>Applications 1,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one (Ondansetron EP Impurity D; Ondansetron USP Related Compound D) is an impurity of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feng, R. et al.: Zhong. Yaox. Zaz., 46, 1436 (2011); Zizkovsky, V. et al.: J. Pharm. Biomed. Anal., 44, 1048 (2007)<br></p>Formula:C14H13NOColor and Shape:WhiteMolecular weight:211.261-(3-Hydroxypropyl)theobromine
CAS:Controlled ProductFormula:C10H14N4O3Color and Shape:White To Off-WhiteMolecular weight:238.243Nimodipine-d7
CAS:Controlled Product<p>Applications A labelled dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral).<br>References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),<br></p>Formula:C21H19D7N2O7Color and Shape:NeatMolecular weight:425.48Deacetyl Ketoconazole
CAS:Controlled Product<p>Impurity Ketoconazole EP Impurity D<br>Applications Deacetyl Ketoconazole (Ketoconazole EP Impurity D) is a Ketoconazole derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C24H26Cl2N4O3Color and Shape:Off-WhiteMolecular weight:489.391-Methoxy Empagliflozin
CAS:Controlled Product<p>Applications 1-Methoxy Empagliflozin is an impurity in the synthesis of Empagliflozin drug (E521510), which is potent and selective inhibitor of sodium glucose co-transporter-2 (SGLT-2).<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Formula:C24H29ClO8Color and Shape:White To Off-WhiteMolecular weight:480.94(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane Hydrochloride
CAS:Controlled ProductFormula:C12H17NO2·ClHColor and Shape:NeatMolecular weight:243.736-Chloro-pyrimidine-2,4-diamine
CAS:Controlled Product<p>Impurity Minoxidil EP Impurity B<br>Applications 6-Chloro-pyrimidine-2,4-diamine (cas# 156-83-2) is a compound useful in organic synthesis.<br></p>Formula:C4H5ClN4Color and Shape:WhiteMolecular weight:144.56Azobenzene
CAS:<p>Applications Impurity in the production of Phenylbutazone (P319570). Dyes and metabolites.<br>References Chung, K., et al.: Mutation Res., 114, 269 (1983), Kawanishi, S., et al.: J. Biol. Chem., 261, 5952 (1986), Floyd, R., et al.: Carcinogenesis, 11, 1447 (1990), Shibutani, S., et al.: Nature, 349, 431 (1991),<br></p>Formula:C12H10N2Color and Shape:NeatMolecular weight:182.22Saxagliptin Hydrate
CAS:Controlled Product<p>Applications Saxagliptin Hydrate is a selective and reversible dipeptidyl peptidase-4 (DPP4) inhibitor that may be used to develop treatment for type 2 diabetes.<br>References Gu, S., et al.: PLoS One. 11, e0167190 (2016); Dave, D. J.: J Pharmacol Pharmacother 2, 230 (2011)<br></p>Formula:C18H25N3O2·H2OColor and Shape:NeatMolecular weight:333.432-Descarboxy-2-cyano Telmisartan
CAS:<p>Impurity Telmisartan EP Impurity G<br>Applications 2-Descarboxy-2-cyano Telmisartan (Telmisartan EP Impurity G) is an impurity of the angiotensin II receptor antagonist, Telmisartan (T017000).<br>References Reddy, M.R. et al.: Int. J. Pharm. Pharmac. Sci., 4, 497 (2012);<br></p>Formula:C33H29N5Color and Shape:NeatMolecular weight:495.62Argatroban Ethyl Ester
Controlled ProductFormula:C25H40N6O5SColor and Shape:NeatMolecular weight:536.6871-Amino-3-adamantanol
CAS:Controlled Product<p>Applications Reagent used in the preparation of Vildagliptin.<br>References Fukushima, H., et al.: Bioorg. Med. Chem., 16, 4093 (2008), Anand, R., et al.: J. Med. Chem., 52, 1602 (2009),<br></p>Formula:C10H17NOColor and Shape:NeatMolecular weight:167.25Iloperidone-d3
CAS:Controlled Product<p>Applications Labelled Iloperidone. Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sainati, S.M., et al.: J. Clin. Pharmacol., 35, 713 (1995), Szewczak, M.R., et al.: J. Pharmacol. Exp. Ther., 274, 1404 (1995), Kongsamut, S., et al.: Eur. J. Pharmacol., 317, 417 (1996)<br></p>Formula:C24H24D3FN2O4Color and Shape:Light YellowMolecular weight:429.5Axitinib Tetrahydro-2H-pyran
CAS:Controlled ProductFormula:C27H26N4O2SColor and Shape:NeatMolecular weight:470.586(+/-)-Epinephrine Hydrochloride
CAS:Controlled Product<p>Applications (+/-)-Epinephrine hydrochloride is an adrenergic receptor agonist; Neurotransmitter; Causes suppression of efferent activity of the adrenal nerve.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirano, T., et al.: J. Auton. Nerv. Syst., 1, 283-290 (1980)<br></p>Formula:C9H13NO3·ClHColor and Shape:Off-WhiteMolecular weight:219.67Meloxicam-d3
CAS:Controlled Product<p>Applications Labelled form of Meloxicam. Preferential cyclooxygenase (COX-2) inhibitor. Used as an anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hawkey, C., et al.: Br. J. Rheumatol., 35, Suppl. 1, 1 (1996), Fleischmann, R., et al.: Expert Opin. Pharmacother., 3, 1501 (2002),<br></p>Formula:C142H3H10N3O4S2Color and Shape:Light Yellow To YellowMolecular weight:354.42Desisopropyl Atrazine-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Atrazine (ATR) (A794600).<br>References Compton, D., et al.: Eur. J. Pharmacol., 110, 157 (1985), Das, P., et al.: Toxicol. Sci., 59, 127 (2001), Das, P., et al.: Life Sci., 73, 3123 (2003), Coban, A., et al.: J. Neurochem., 100, 1177 (2007),<br></p>Formula:C52H5H3ClN5Color and Shape:Off-WhiteMolecular weight:178.63Asenapine N-Oxide
CAS:Controlled Product<p>Applications A metabolite of Asenapine (A788000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ven der Wildenberg, H.M., et al.: Arzneim.-Forsch., 40, 540 (1990),<br></p>Formula:C17H16ClNO2Color and Shape:NeatMolecular weight:301.77Reserpine-d9
CAS:Controlled Product<p>Applications Labelled Reserpine (R144600). An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive.<br>References Muller, J.M., et al.: Experientia, 8, 338 (1952), Schirmer, R.E., et al.: Anal. Profiles Drug Subs., 4, 384 (1975), Diener, R.M., et al.: Toxicol. Pathol., 8, 1 (1980),<br></p>Formula:C332H9H31N2O9Color and Shape:NeatMolecular weight:617.734-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride
CAS:<p>Applications 4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride is a derivative of (4-Methoxyphenyl)hydrazine Hydrochloride (M265880). It is a useful synthetic intermediate for the preparation of Indomethacin (I641000); a potent, time-dependent, nonselective inhibitor of the cyclooxygenase enzymes COX-1 and COX-2.<br>References Blobaum, Anna L., et al.: ACS Med. Chem. Lett., 4(5), 486-490 (2013); Prusakiewicz, Jeffery J., et al.: Biochemistry, 43(49), 15439-15445 (2004)<br></p>Formula:C14H13ClN2O2·HClColor and Shape:NeatMolecular weight:313.18N-Nitrosooxprenolol
CAS:Controlled ProductFormula:C15H22N2O4Color and Shape:Light YellowMolecular weight:294.346Rimonabant Hydrochloride
CAS:Controlled Product<p>Applications Rimonabant Hydrochloride is a potent and selective CB1 cannabinoid antagonist used to investigate CB receptor properties (1). Rimonabant Hydrochloride is also an anti-obesity agent (2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Carai, M.A.M., et al.: Life Sci., 77, 2339 (2005) (2) Janiak, P., et al.: Kidney Int. 72, 1345 (2007)<br></p>Formula:C22H21Cl3N4O·ClHColor and Shape:White To Off-WhiteMolecular weight:500.25Propylthiouracil N-β-D-Glucuronide Sodium Salt
CAS:Controlled Product<p>Applications Salt of Propylthiouracil N-β-D-Glucuronide (P838315), also a metabolite of Propylthiouracil (P838310).<br>References Lindsay, R. H., et al.: J. Pharm. Sci., 63 1383 (1974)Taurog, A., et al.: Endocrinology, 122, 592 (1988),<br></p>Formula:C13H17N2NaO7SColor and Shape:NeatMolecular weight:368.344-Benzyloxybenzylidene 4-Fluoroaniline
CAS:Controlled ProductFormula:C20H16FNOColor and Shape:Dark OrangeMolecular weight:305.35Rivaroxaban-d4
CAS:Controlled ProductFormula:C19H14D4ClN3O5SColor and Shape:White To Off-WhiteMolecular weight:439.914-Desmethoxypropoxyl-4-chloro Rabeprazole
CAS:Controlled Product<p>Impurity Rabeprazole EP Impurity H (Lansoprazole EP Impurity F)<br>Applications 4-Desmethoxypropoxyl-4-chloro Rabeprazole (Rabeprazole EP Impurity H (Lansoprazole EP Impurity F)) is a process impurity of Rabeprazole (R070500).<br></p>Formula:C14H12ClN3OSColor and Shape:NeatMolecular weight:305.78(2R,4R)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol 4-(4-Methylbenzenesulfonate)
CAS:Controlled ProductFormula:C21H20Cl2N2O5SColor and Shape:NeatMolecular weight:483.3654-(2-Aminophenyl)-3-morpholinone
CAS:<p>Applications 4-(2-Aminophenyl)-3-morpholinone is a reagent used in the preparation of various Morpholine based pharmaceuticals.<br>References Mederski, W., et al.: Bioorg. Med. Chem. Lett., 14, 3763 (2004), Roehrig, S., et al.: J. Med. Chem., 48, 5900 (2005),<br></p>Formula:C10H12N2O2Color and Shape:Off White SolidMolecular weight:192.214Nitisinone-13C6
CAS:<p>Applications Labelled Nitisinone. Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I.<br>References Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998),<br></p>Formula:C813C6H10F3NO5Color and Shape:Light Beige To BrownMolecular weight:335.18Ethyl Ethanesulfonate
CAS:Controlled Product<p>Applications Ethyl Ethanesulfonate is used as a reactant in stereoselective Friedel-Crafts alkylation reactions. Also used in the preparation of 1-alkyl-3-methylimidazolium alkanesulfonate ionic liquids.<br>References Stadler, D., Bach, T.: Chem. Asian J., 3, 272 (2008); Blesic, M., et al.: Phys. Chem. Chem. Phys., 11, 8939 (2009);<br></p>Formula:C4H10O3SColor and Shape:NeatMolecular weight:138.19rac 8,14-Dihydroxy Efavirenz-d4
CAS:Controlled Product<p>Applications A labelled metabolite of Efavirenz (E425000) (secondary metabolism).<br>References Gorski, J., et al.: Biochem. Pharmacol., 47, 1643 (1994), Desta, Z., et al.: J. Pharmacol. Exp. Ther., 285, 428 (1998), Langmann, P., et al.: Eur. J. Med. Res., 7, 309 (2002), Chang, T., et al.: Drug Metab. Dispos., 31, 7 (2003),<br></p>Formula:C14H5D4ClF3NO4Color and Shape:NeatMolecular weight:351.70Pibrentasvir
CAS:Controlled Product<p>Applications Pibrentasvir (CAS# 1353900-92-1) is an antiviral used for hepatitis C virus NS3/4A protease inhibition.<br>References Ng, T. I.; et al.: Antimicrob. Agents Chemother., 62, 1 (2018).<br></p>Formula:C57H65F5N10O8Color and Shape:Off-White To Light YellowMolecular weight:1113.18
![3-[2-(3,4-dimethoxyphenyl)ethyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF988576.webp&w=3840&q=75)
![2-METHOXY-5-(5-(PYRIDIN-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PHENOL](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF332581.webp&w=3840&q=75)
![2-[5-bromo-2-(pyridin-2-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF526132.webp&w=3840&q=75)
![6-Amino-4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-7-ethoxyquinoline-3-carbonitrile](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF788588.webp&w=3840&q=75)
![2-((2R,3R)-3-(tert-butyl)-4-methoxy-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF604795.webp&w=3840&q=75)
![(2S,2'S)-1,1'-[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)imino]bis(1-oxo-2,1-ethanediyl)]bis-2-pyrro…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FH971385.webp&w=3840&q=75)
![4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA616975.webp&w=3840&q=75)
![(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane Hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD461760.webp&w=3840&q=75)
