Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65541 products of "Quinazoline and Quinoline Derivatives"
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4-(4-Chloro-pyrazol-1-ylmethyl)-phenylamine
CAS:Formula:C10H10ClN3Purity:97%Color and Shape:SolidMolecular weight:207.664-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide
CAS:<p>Applications 4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide is an impurity of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Formula:C15H17N3O2SColor and Shape:White To Light YellowMolecular weight:303.38Sibutramine, Hydrochloride Monohydrate
CAS:Controlled ProductFormula:C17H26ClN·ClH·H2OColor and Shape:Off White SolidMolecular weight:334.323-(2-Amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile
CAS:Purity:98.0%Molecular weight:426.48400878906252-Pyridin-3-yl-benzofuran-5-carboxylic acid methyl ester
Purity:95.0%Molecular weight:253.25700378417975-(1,3-Dioxolan-2-yl)-2-(4-isopropylbenzoyl)thiophene
CAS:Purity:97.0%Molecular weight:302.3900146484375N-pyridin-3-yl-2-(tetrahydro-2H-pyran-4-ylcarbonyl)hydrazinecarbothioamide
Molecular weight:280.35000610351562-(3,4-Dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Purity:97.0%Molecular weight:288.35998535156253-methyl-1-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-1H-pyrazol-5-amine
CAS:Purity:95.0%Molecular weight:291.3179931640625TERT-BUTYL 3-(THIOPHEN-2-YL)PYRROLIDINE-1-CARBOXYLATE
CAS:Purity:95.0%Molecular weight:253.360000610351563-Amino-5-(4-benzyloxyphenyl)thiophene-2-carboxylic acid methyl ester
CAS:Purity:99.0%Color and Shape:SolidMolecular weight:339.4100036621094Olanzapine
CAS:Controlled Product<p>Applications Olanzapine is a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity. Antipsychotic. Neuroprotective product.<br>References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)<br></p>Formula:C17H20N4SColor and Shape:Light Yellow CrystallineMolecular weight:312.43Everolimus
CAS:Controlled Product<p>Impurity Everolimus EP Impurity C<br>Stability Hygroscopic<br>Applications Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>Formula:C53H83NO14Purity:~90%Color and Shape:NeatMolecular weight:958.222-Methoxy Phenothiazine
CAS:<p>Applications An impurity of Methotrimeprazine (M260785).A derivative of Phenothiazine (P318040) exhibits tuberculostatic activity.<br>References Waisser, K., et al.: Folia. Pharm. Univ. Carol., 18, 41 (1995)<br></p>Formula:C13H11NOSColor and Shape:Grey To BrownMolecular weight:229.30N-[(2E)-1-[(4-Nitrophenyl)methoxy]-1,2-dihydropyridin-2-ylidene]benzenesulfonamide
Molecular weight:385.3900146484375Afatinib-d6
CAS:Controlled ProductFormula:C24H19D6ClFN5O3Color and Shape:Light Yellow SolidMolecular weight:491.98MDV 3100 (Enzalutamide)
CAS:Controlled Product<p>Applications MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.<br>References Scher, H.I. et al.: Lancet, 375, 1437 (2010); Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010); Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2011);<br></p>Formula:C21H16F4N4O2SColor and Shape:WhiteMolecular weight:464.442,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
CAS:Controlled Product<p>Applications Varenicline intermediate.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005),<br></p>Formula:C13H14F3N3OColor and Shape:NeatMolecular weight:285.261,5-Dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid
CAS:Purity:95.0%Molecular weight:167.164001464843754,4',5,5'-Tetra(pyridin-4-yl)-2,2'-bi(1,3-dithiolylidene)
CAS:Purity:98%Molecular weight:512.6799926757812Lansoprazole Sulfone
CAS:<p>Impurity Lansoprazole USP Related Compound A<br>Applications A metabolite of Lansoprazole, as gastric pump inhibitor. Lansoprazole USP Related Compound A.<br>References De Morais, S., et al.: Mol. Pharmacol., 46, 594 (1994), Spencer, C., et al.: Drugs, 48, 404 (1994), Pearce, R., et al.: J. Pharmacol. Exp. Ther., 277, 805 (1996), Tassaneeyakul, W., et al.: Br. J. Clin. Pharmacol., 49, 139 (2000),<br></p>Formula:C16H14F3N3O3SColor and Shape:NeatMolecular weight:385.36(S)-Lansoprazole
CAS:Controlled Product<p>Applications The S-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),<br></p>Formula:C16H14F3N3O2SColor and Shape:NeatMolecular weight:369.365-Morpholinopyridin-3-amine trihydrochloride
CAS:Color and Shape:SolidMolecular weight:288.6000061035156PD 169,316
CAS:<p>M02298 - PD 169,316</p>Formula:C20H13FN4O2Purity:>98%Color and Shape:SolidMolecular weight:360.3479919433594Retigabine N-β-D-Glucuronide Sodium Salt
CAS:Controlled Product<p>Applications Sodium salt of Retigabine N-β-D-Glucuronide is the major metabolite of the antiepileptic drug Retigabine (R189050) that is produced via N-glucuronidation in humans.<br>References Hiller, A. et al.: Drug Metab. Dispos., 27, 605 (1999); Borlak, J. et al.: Metab. Clin. Exp., 55, 711 (2006); McNeilly, P.P. et al.: Zenobiotica, 27, 431 (1997);<br></p>Formula:C22H25FN3NaO8Color and Shape:NeatMolecular weight:501.445-Hydroxy Omeprazole (~5% Triethylamine as stabilizer)
CAS:<p>Stability Hygroscopic, Temperature Sensitive<br>Applications 5-Hydroxy Omeprazole is the main metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O4SColor and Shape:NeatMolecular weight:361.42Risperidone N-Oxide
CAS:Controlled Product<p>Applications Risperidone (R525000) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References El-Sherif, Z., et al.: J. Pharm. Biomed. Anal., 36, 975 (2005), Sattanathan, P., et al.: J. Pharm. Biomed. Anal., 40, 598 (2006),<br></p>Formula:C23H27FN4O3Color and Shape:WhiteMolecular weight:426.482-(((6-(Difluoromethoxy)-1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-3,4-dimethoxypyridine 1-oxide
CAS:Purity:95.00%Molecular weight:399.36999511718753,5-(Dimethyl-1H-pyrazol-4yl)methylamine
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:125.175003051757813-Methyl-2-phenylquinoline-4-carboxylic acid
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:263.29598999023444-(4-Phenylbutoxy)benzoic Acid
CAS:Controlled Product<p>Applications 4-(4-PHENYLBUTOXY)BENZOIC ACID (cas# 30131-16-9) is a useful research chemical.<br></p>Formula:C17H18O3Color and Shape:NeatMolecular weight:270.322-Methyl-6-(trifluoromethyl)nicotinonitrile
CAS:Purity:95%Color and Shape:Solid, Off white solidMolecular weight:186.136993408203122-(2,3-Dimethoxybenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Purity:97.0%Molecular weight:320.3599853515625Hydroxy Dehydro Nifedipine Lactone
CAS:Controlled ProductFormula:C16H12N2O6Color and Shape:NeatMolecular weight:328.28[[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyl]oxirane
CAS:Controlled ProductFormula:C15H20O3Color and Shape:NeatMolecular weight:248.322-(thiophen-2-yl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine
CAS:Purity:95.0%Molecular weight:230.33000183105472-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide
CAS:Controlled ProductFormula:C11H10ClN3OSColor and Shape:NeatMolecular weight:267.732-Cyclopropyl-quinoline-4-carboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:213.23599243164062
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