Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65624 products of "Quinazoline and Quinoline Derivatives"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
4-Desmethyl-2-methyl Celecoxib
CAS:Controlled Product<p>Applications 4-Desmethyl-2-methyl Celecoxib is an analog of Celecoxib (C251000). It is a cyclooxygenase 2 inhibitor.<br>References Penning, T., et al.: J. Med. Chem., 40, 1347 (1997); Wesolowski, S., et al.: Bioorg. Med. Chem. Lett., 12, 267 (2002)<br></p>Formula:C17H14F3N3O2SColor and Shape:White To BeigeMolecular weight:381.37Ethionamide-d3
CAS:Controlled Product<p>Applications Ethionamide-d3 is the isotope labelled analogue of Ethionamide (E890420), a antibacterial (tuberculostatic) agent.<br>References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),<br></p>Formula:C8H7D3N2SColor and Shape:NeatMolecular weight:169.263-Hydroxy-2-pyrone
CAS:Controlled Product<p>Applications 3-Hydroxy-2-pyrone<br></p>Formula:C5H4O3Color and Shape:NeatMolecular weight:112.081-Phenyl-1,2-propanediol (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications 1-Phenyl-1,2-propanediol is a reagent in pharmaceutical chemistry, used in the synthesis of nor(pseudo)ephedrine related compounds.<br>References Sehl, T. et al.: Green Chem., 16, 3341 (2014); Moorthy, J. et al.: J. Org. Chem., 76, 9593 (2011);<br></p>Formula:C9H12O2Color and Shape:NeatMolecular weight:152.19Ibrutinib
CAS:Controlled Product<p>Applications Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.<br>References MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)<br></p>Formula:C25H24N6O2Color and Shape:Off-WhiteMolecular weight:440.503-((2-CHLOROPYRIDIN-4-YL)METHYL)-1-CYCLOBUTYL-6,7,8,9-TETRAHYDRO-3H-PYRAZOLO[3,4-C]ISOQUINOLIN-5(4H)-ONE
CAS:Purity:95.0%Molecular weight:368.8699951171875Ethyl 5-Pyridin-4-yl-1,2,4-oxadiazole-3-carboxylate
CAS:Purity:97.0%Molecular weight:219.19999694824225-(Pyridin-2-yl)thiophene-2-carbaldehyde
CAS:Formula:C10H7NOSPurity:97.0%Color and Shape:SolidMolecular weight:189.23Tipranavir
CAS:<p>Applications Nonpeptidic HIV protease inhibitor (NPPI). Antiviral.<br>References Poppe, S.M., et al.: Antimicrob. Agents Chemother., 41, 1058 (1997), McGregor, T.R., et al.: HIV Clin. Trials, 5, 371 (2004), Boffito, M., et al.: J. Clin. Pharmacol., 46, 130 (2006),<br></p>Formula:C31H33F3N2O5SColor and Shape:NeatMolecular weight:602.66Ref: 10-F673022
1gTo inquire2gTo inquire5gTo inquire10gTo inquire100mgTo inquire250mgTo inquire500mgTo inquire1-Methyl-4-[5-(2-methylsulfamoylethyl)-1H-indol-3-yl]pyridinium Chloride
Controlled Product<p>Impurity Naratriptan pyridinium Impurity<br>Stability Hygroscopic<br>Applications Naratriptan (N378730) impurity.<br></p>Formula:C17H20ClN3O2SColor and Shape:NeatMolecular weight:365.882-Chloro-5-(2-phenyl-5-(pyridin-4-yl)-1H-imidazol-4-yl)phenol
CAS:Purity:95.0%Molecular weight:347.79998779296875Felodipine Ester Lactone
CAS:Controlled Product<p>Applications Felodipine Ester Lactone is an intemediate used in the synthesis of Dehydro Felodipine Ester Lactone (D229690), which is a metabolite of Felodipine (F232375).<br>References Wang, S.X. et al.: J. Pharmacol. Exp. Therap., 250, 632 (1989); Baeaernhielm, C. et al.: Drug Metab. Disp., 14, 613 (1986);<br></p>Formula:C17H15Cl2NO4Color and Shape:NeatMolecular weight:368.211-Difluoromethyl-3,5-dimethyl-1H-pyrazole-4-sulfonyl chloride
CAS:Formula:C6H7ClF2N2O2SColor and Shape:LiquidMolecular weight:244.648-Methyl-2-pyridin-2-yl-quinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:264.283996582031254-Defluoro 2-Fluoro Flunarizine Dihydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 4-Defluoro 2-Fluoro Flunarizine Dihydrochloride is an impurity of Flunarizine(F455200, Dihydrochloride), which is a calcium channel blocker. Flunarizine is a fluorinated derivative of Cinnarizine and a vasodilator (cerebral and peripheral).<br>References Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975), Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979), Nihard, P., et al.: Angiology, 33, 37 (1982), Holmes, B., et al.: Drugs, 27, 6 (1984)<br></p>Formula:C26H26F2N2HClColor and Shape:White SolidMolecular weight:404.4923646Omeprazole Sulfone
CAS:<p>Impurity USP Omeprazole Related Compound A<br>Applications A metabolite of Omeprazole.<br></p>Formula:C17H19N3O4SColor and Shape:White To Light BrownMolecular weight:361.42N-Deshydroxyethyl Dasatinib-d8
CAS:Controlled ProductFormula:C21D8H15ClN6OSColor and Shape:White SolidMolecular weight:451.017-Hydroxy Loxapine
CAS:Controlled Product<p>Applications 7-Hydroxy Loxapine is a metabolite of Loxapine (L472750), a neuroleptic medication used to treat patients with schizophrenia and obsessive compulsive disorder.<br>References Kapur, S., et al.: Am. J. Psychiatry, 154, 1525 (1997); Rivers-Bulkeley, N. & Hollender, M.: Am. J. Psychiat., 139, 1345 (1982)<br></p>Formula:C18H18ClN3O2Color and Shape:NeatMolecular weight:343.81Celecoxib Carboxylic Acid
CAS:Controlled ProductFormula:C17H12F3N3O4SColor and Shape:Off WhiteMolecular weight:411.362-bromo-1-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]ethanone hydrobromide
CAS:Purity:TECHMolecular weight:362.97198486328125(S)-Naproxen Acyl-β-D-glucuronide
CAS:<p>Applications A metabolite of Naproxen.<br>References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Jin, C., et al.: J. Pharmacol. Exp. Ther., 264, 475 (1993),King, C., et al.: Toxicol. Sci., 61, 49 (2001), Aresta, A., et al.: J. Pharm. Biomed. Anal., 39, 643 (2005),<br></p>Formula:C20H22O9Color and Shape:NeatMolecular weight:406.38Bis-[Des(5-Chloro-2-carboxythienyl)] Rivaroxaban Phthalamide
CAS:Controlled ProductFormula:C36H36N6O10Color and Shape:NeatMolecular weight:712.71Methyl 6-bromo-2-(4-methoxyphenyl)quinoline-4-carboxylate
CAS:Purity:95.0%Molecular weight:372.21798706054691-Quinoxalin-2-yl-piperidin-4-ylamine hydrochloride
CAS:Purity:95.0%Molecular weight:264.7600097656252,6-Dimethoxypyridine-3,5-diamine hydrochloride
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:205.63999938964844Sitagliptin-d4 Phosphate
CAS:Controlled Product<p>Applications A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.<br>References Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006).<br></p>Formula:C162H4H11F6N5O·H3O4PColor and Shape:Off-WhiteMolecular weight:509.33N-Chloromethyl Olanzapine Chloride
CAS:Controlled Product<p>Impurity Olanzapine EP Impurity C<br>Applications N-Chloromethyl Olanzapine Chloride (Olanzapine EP Impurity C) is an impurity of Olanzapine (O253750).<br>References Moore, N., et al.: J. Pharmacol. Exper. Ther., 262, 545 (1992), Tamminga, C., et al.: J .Neural .Transm., 109, 411 (2002), Moore, N., et al.: Curr. Opin Invest Drugs, 2, 281 (1993),<br></p>Formula:C18H22ClN4S·ClColor and Shape:NeatMolecular weight:397.37
![3-((2-CHLOROPYRIDIN-4-YL)METHYL)-1-CYCLOBUTYL-6,7,8,9-TETRAHYDRO-3H-PYRAZOLO[3,4-C]ISOQUINOLIN-5(4…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF386429.webp&w=3840&q=75)
![1-Methyl-4-[5-(2-methylsulfamoylethyl)-1H-indol-3-yl]pyridinium Chloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM321050.webp&w=3840&q=75)
![Tert-Butyl N-[1-(quinazolin-4-yl)azetidin-3-yl]carbamate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF091366.webp&w=3840&q=75)
![2-bromo-1-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]ethanone hydrobromide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF518747.webp&w=3840&q=75)
![Bis-[Des(5-Chloro-2-carboxythienyl)] Rivaroxaban Phthalamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FB415135.webp&w=3840&q=75)
