Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65630 products of "Quinazoline and Quinoline Derivatives"
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Pseudo Vardenafil
CAS:<p>Applications Vardenafil analog.<br>References Blok-Tip, L., et al.: Food Addit. Contam., 21, 737 (2004), Reffelmann, T., et al.: Curr. Pharm. Des., 12, 3485 (2006), Reepmeyer, J., et al.: J. Pharm. Biomed. Anal., 43, 1615 (2007),<br></p>Formula:C22H29N5O4SColor and Shape:NeatMolecular weight:459.56N-Phenoxycarbonylparoxetine
CAS:Controlled Product<p>Applications N-Phenoxycarbonylparoxetine is an impurity of Paroxetine (P205750), a selective serotonin reuptake inhibitor. Used as an antidepressant.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982),<br></p>Formula:C26H24FNO5Color and Shape:NeatMolecular weight:449.47Gabapentin-d4 (100 μg/mL in Methanol)
CAS:Controlled ProductFormula:C9D4H13NO2Color and Shape:Single SolutionMolecular weight:175.262-(2-methyl-1H-indol-3-yl)-N-(thiophen-2-ylmethyl)ethan-1-amine hydrochloride
CAS:Purity:95.0%Molecular weight:306.8500061035156[2-(1H-indol-3-yl)ethyl][(pyridin-4-yl)methyl]amine hydrochloride
CAS:Purity:95.0%Molecular weight:287.7900085449219N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-nitroquinazolin-4-yl)acetamide
CAS:Purity:97.0%Molecular weight:390.760009765625Afatinib, Free Base
CAS:Purity:99.0%Color and Shape:Solid, No data available.Molecular weight:485.94000244140625Pamabrom
CAS:Controlled Product<p>Applications A diuretic used to reduce menstrual pains.<br>References Varga, J., et al.: Mol. Immunol., 28, 641 (1991), Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005), Ibrahim, H., et al.: Drug Discov. Ther., 3, 168 (2009),<br></p>Formula:C7H7BrN4O2·C4H11NOColor and Shape:NeatMolecular weight:348.204-[6-(4-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Purity:95.0%Molecular weight:278.31500244140625Cabozantinib N-oxide
CAS:Controlled Product<p>Applications Cabozantinib N-oxide is a impurity of Cabozantinib (X745500), a medication used to treat medullary thyroid cancer. As well, it can be used in biological study. Computational network biological approach based on pathway cross-talk inhibition identified new synergistic drug combinations using raloxifene and cabozantinib for treatment of human breast cancer in xenograft mouse model. Potent c-MET inhibitor.<br>References Jaeger, S., et al.: Cancer Res, 77, 459-469 (2017)<br></p>Formula:C28H24FN3O6Color and Shape:Off-WhiteMolecular weight:517.513-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:303.3179931640625Ethyl (3-cyano-4,6-dimethylpyridin-2-ylamino)acetate
CAS:Formula:C12H15N3O2Purity:95.0%Color and Shape:SolidMolecular weight:233.271Pyrimethamine-d3
CAS:Controlled Product<p>Applications Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial.<br>References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983), Leport, C., et al.: Am. J. Med., 84, 94 (1988), McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1998), Plowe, C.V., et al.: Br. Med. J., 328, 545 (2004),<br></p>Formula:C12H10D3ClN4Color and Shape:Off-WhiteMolecular weight:251.732-(CHLOROMETHYL)-3,5-DIMETHYL-4-METHOXYPYRIDINE
CAS:Purity:97.0%Color and Shape:Liquid, No data available.Molecular weight:185.64999389648438Everolimus-d4 (>85%)
CAS:Controlled Product<p>Applications Macrolide immunosuppressant; derivative of Rapamycin. Inhibits cytokine-mediated lymphocyte proliferation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>Formula:C532H4H79NO14Purity:>85%Color and Shape:White To Light YellowMolecular weight:962.25Omeprazole-d3 Sulfone
CAS:Controlled ProductFormula:C17H16D3N3O4SColor and Shape:NeatMolecular weight:364.43Doravirine
CAS:<p>Applications Doravirine is a novel non-nucleoside inhibitor of HIV-1 reverse transcriptase with potent activity against wild-type virus.<br>References Feng, M., et al.: Antimicrob Agents Chemother, 60, 2241-7 (2016); Lai, M.T., et al.: Antimicrob Agents Chemother, 58, 1652-63 (2014); Anderson, M.S., et al.: Antivir Ther., 20, 397-405 (2015);<br></p>Formula:C17H11ClF3N5O3Color and Shape:NeatMolecular weight:425.75(2E)-1-{[1,1'-biphenyl]-4-yl}-3-(thiophen-2-yl)prop-2-en-1-one
CAS:Purity:95.0%Molecular weight:290.3800048828125Azasetron-d3 Hydrochloride
CAS:Controlled Product<p>Applications A 5-HT3 receptor antagonist. Used as an antiemetic.<br>References Sato, N., et al.: Japan J. Pharmacol., 59, 443 (1992), Haga, K., et al.: Japan J. Pharmacol., 63, 377 (1993)<br></p>Formula:C172H3H17ClN3O3·ClHColor and Shape:NeatMolecular weight:389.291-(4-Chlorophenyl)-5-(furan-2-yl)-1h-pyrazole-3-carboxylic acid
CAS:Purity:95%Molecular weight:288.69000244140625Gefitinib-d3
CAS:Controlled Product<p>Applications Labelled Gefitinib (G304000). Gefitinib is an antineoplastic.<br>References Anderson, N.G., et al.: Int. J. Cancer, 94, 774 (2001), Hirata, A., et al.: Cancer Res., 62, 2554 (2002), Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003), Tamura, K., et al.: Expert Opin. Pharmacother., 6, 985 (2005),<br></p>Formula:C22H21D3ClFN4O3Color and Shape:NeatMolecular weight:449.92Pimozide N-Oxide
CAS:<p>Applications Pimozide N-Oxide is an impurity of Pimozide (P447800) with hERG inhibitory activity. Pimozide impurity E.<br></p>Formula:C28H29F2N3O2Color and Shape:Off White PowderMolecular weight:477.544-fluoro-2-(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)aniline
CAS:Purity:95.0%Molecular weight:256.239990234375Methyl 3-(3-carbamoyl-4-(3-methoxyphenylamino)-8-methylquinolin-6-ylsulfonyl)benzoate
CAS:Purity:98%Molecular weight:505.54998779296875PD-153,035
CAS:<p>M02324 - PD-153,035</p>Formula:C16H14ClN3O2Purity:>98%Color and Shape:SolidMolecular weight:315.7600097656255-(Dimethylaminomethyl)-2-furfuryl Alcohol Hydrochloride
CAS:Controlled Product<p>Impurity Ranitidine EP Impurity F<br>Stability Hygroscopic<br>Applications 5-(Dimethylaminomethyl)-2-furfuryl Alcohol Hydrochloride (Ranitidine EP Impurity F) is an intermediate in the synthesis of Ranitidine hydrochloride (R120000).<br>References Salameh, A., et al.: J. Food Sci., 71, 10 (2006), Guerrieri, P., et al.: Pharm. Res., 24, 147 (2007),<br></p>Formula:C8H13NO2·ClHColor and Shape:BrownMolecular weight:191.662-(Pyridin-4-ylmethyl)-2,3-dihydro-1H-isoindole-1,3-dione dihydrate
CAS:Purity:98.0%Molecular weight:274.2760009765625Deshydroxyethoxy Ticagrelor
CAS:<p>Applications Deshydroxyethoxy Ticagrelor analog of Ticagrelor (T437700) an antiplatelet agent, and preventative in the treatment of heart attacks, myocardial infarction, and other pulmonary diseases.<br>References Zhang, H. et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012);<br></p>Formula:C21H24F2N6O3SColor and Shape:White To Off-WhiteMolecular weight:478.52N-(7-BROMOISOQUINOLIN-3-YL)CYCLOPROPANECARBOXAMIDE
CAS:Purity:95.0%Molecular weight:291.14801025390625Dermofungin
CAS:Controlled Product<p>Applications Dermofungin, is an impurity of Cioquinol, which is an antifungal and antiprotozoal drug.<br>References Hongchao, J., et al.: Cancer Lett., 312, 11 (2011); LeVine, H., et al.: Neuroscience Lett., 465, 99 (2009);<br></p>Formula:C9H6ClNOColor and Shape:NeatMolecular weight:179.60N-Nitrosomorpholine-d8
CAS:Controlled Product<p>Applications N-Nitrosomorpholine-d8 (CAS# 1219805-76-1) is a useful isotopically labeled research compound.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C42H8N2O2Color and Shape:Light YellowMolecular weight:124.171-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl-7-hydroxy-3,4-dihydro Carbostyril (Aripiprazole Imp
CAS:<p>Applications This compound is an impurity in the synthesis of Aripiprazole (A771000) which is a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998), Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998),<br></p>Formula:C23H27Cl2N3O2Color and Shape:NeatMolecular weight:448.39Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid
CAS:Controlled Product<p>Applications Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid is a reactant used in the preparation of peptidase IV inhibitors.<br>References Park, W. et al.: Bioorg. Med. Chem. Lett., 21, 1366 (2011);<br></p>Formula:C15H18F3NO4Color and Shape:NeatMolecular weight:333.35-Chloro-7-[(4-methylpiperidin-1-yl)methyl]quinolin-8-ol
CAS:Purity:95.0%Molecular weight:290.7900085449219o-Flutamide
CAS:Controlled Product<p>Impurity Flumazenil EP Impurity F<br>Applications o-Flutamide is an isomer of Flutamide (F598850), a nonsteroidal antiandrogen drug; antineoplastic (hormonal).<br>References Neri, et al.: Endocrinology, 91, 427 (1972), Sogani, P.C., et al.: J. Urol., 122, 640 (1979), Greenway, B.A., et al.: Br. Med. J., 316, 1935 (1998),<br></p>Formula:C11H11F3N2O3Color and Shape:NeatMolecular weight:276.214-Chloro-2-methyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidine
CAS:Purity:95%Molecular weight:266.760009765625rac-Praziquanamine
CAS:Controlled Product<p>Applications Praziquanamine, as the main intermediate for synthesizing antiparasitic agent Praziquantel (P702095).<br>References Dong, Y., et al.: Bioorg. Med. Chem. Lett., 20(8), 2481 (2010)<br></p>Formula:C12H14N2OColor and Shape:NeatMolecular weight:202.25245-p-Tolyl-1H-pyrazole-3-carboxylic acid methyl ester
CAS:Purity:95.0%Molecular weight:216.24000549316406α-Ethyl Norepinephrine Hydrochloride (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications A bronchodilator.<br>References Daly, J. W., et al.: J. Med. Chem., 9(3), 273 (1966).<br></p>Formula:C10H15NO3·ClHColor and Shape:NeatMolecular weight:233.69
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