Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4948 products of "Steroids and Derivatives"
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Cortodoxone
CAS:<p>Cortodoxone (11-Desoxycortisol) is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.</p>Formula:C21H30O4Purity:99.26% - 99.87%Color and Shape:SolidMolecular weight:346.46Fluocortolone Impurity 1
CAS:Formula:C27H37FO5Color and Shape:White To Off-White SolidMolecular weight:460.59D-Homo B Derivative of Prednisolone
Formula:C21H29O8PColor and Shape:Off-White SolidMolecular weight:440.43Methylprednisolone Impurity 51
CAS:Formula:C22H28O5Color and Shape:White To Off-White SolidMolecular weight:372.46Desoximetasone
CAS:<p>Desoximetasone (Topicort) is a topical corticosteroid for treating skin conditions like rashes.</p>Formula:C22H29FO4Purity:99.06% - 99.89%Color and Shape:SolidMolecular weight:376.46Zeaxanthin
CAS:<p>Zeaxanthin is a dietary carotenoid that accumulates in the retina (particularly the macula) and has antioxidant activity.Cost-effective and quality-assured.</p>Formula:C40H56O2Purity:98.15% - 99.44%Color and Shape:SolidMolecular weight:568.8717-α-Ethynyl Estradiol-3-Sulfate-d7 Triethylamine Salt
Formula:C20H17D7O5S·C6H15NMolecular weight:383.51 101.19Testosterone-2,2,4,6,6-d5 (1 mg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C192H5H23O2Color and Shape:ColourlessMolecular weight:293.46Dutasteride
CAS:Controlled Product<p>Applications Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Formula:C27H30F6N2O2Color and Shape:NeatMolecular weight:528.53Digitoxin-21,23,23-d3
CAS:Controlled Product<p>Applications Isotope labelled Digitoxin (D445950), is used as a cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Foerster, et al.: Arch. Int. Pharmacodyn. Ther., 159, 1 (1966), Jakovljevic, I.M., Anal. Profiles Drug Subs., 3, 149 (1974)<br></p>Formula:C41H61D3O13Purity:90%Color and Shape:NeatMolecular weight:767.96Prednisolone 17-Acetate
CAS:Controlled Product<p>Applications Prednisolone 17-Acetate is an intermediate in the preparation of anti-inflammatory drugs.<br>References Yoon, Kyoung-Jin, et al.: Steroids, 60(7), 445-51 (1995);Uszycka-Horawa, Teresa, et al.: Pol., PL 161012 B1 19930531 (1993)<br></p>Formula:C23H30O6Color and Shape:NeatMolecular weight:402.48Dexamethasone-d5
CAS:Controlled Product<p>Applications A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Formula:C222H5H24FO5Color and Shape:NeatMolecular weight:397.493-O-Methyl Estrone
CAS:Controlled ProductFormula:C19H24O2Color and Shape:White To Dark BrownMolecular weight:284.3917-epi-Norethindrone
CAS:Controlled Product<p>Impurity Norethindrone EP Impurity G<br>Applications Norethindrone (N676000) epimer. Norethindrone and acetate is used in combination with estrogen as contraceptive (oral). Norethindrone EP Impurity G.<br>References Angel, P., et al.: Biochim. Biophys. Acta., 1072, 129 (1991), Chenu, C., et al.: J. Cell Biol., 127, 1149 (1994), Schmidt, M., et al.: J. Endocrinol., 158, 401 (1998),<br></p>Formula:C20H26O2Color and Shape:Off White SolidMolecular weight:298.42Testosterone Undecanoate-d3
CAS:Controlled Product<p>Applications A Labelled metabolite of Testosterone (T155000). It is a promising androgen for male hormonal contraception.CONTROLLED SUBSTANCE<br>References Glass, A., et al.: J. Clin. Endocrinol. Metab., 45, 1211 (1977), Behre, H., et al.: Eur. J. Endocrinol., 140, 414 (1999), Nieschlag, E., et al.: Steroids, 68, 965 (2003), Wang, C., et al.: J. Clin. Endocrinol. Metab., 91, 460 (2006),<br></p>Formula:C30H45D3O3Color and Shape:NeatMolecular weight:459.7214,15-Dehydro Budesonide
CAS:Controlled Product<p>Impurity Budesonide EP Impurity E<br>Applications 14,15-Dehydro Budesonide (Budesonide EP Impurity E) is a Budesonide (B689490) impurity.<br>References Aherne, G., et al.: J. Steroid Biochem., 17, 559 (1982), Assi, K., et al.: J. Pharm. Biomed. Anal., 41, 325 (2006),<br></p>Formula:C25H32O6Color and Shape:WhiteMolecular weight:428.51820(S)-Hydroxy Prednisolone
CAS:Controlled Product<p>Impurity Prednisolone EP Impurity G<br>Applications 20(S)-Hydroxy Prednisolone (Prednisolone EP Impurity G) is a Prednisolone (P703740) metabolite.<br>References Kim, H., et al.: J. Med. Chem., 30, 2239 (1987), Addison, R., et al.: J. Steroid Biochem., Mol. Biol., 39, 83 (1991),<br></p>Formula:C21H30O5Color and Shape:NeatMolecular weight:362.469,11-Didehydrooestriol
CAS:Controlled Product<p>Impurity Estriol EP Impurity A<br>Stability Hygroscopic<br>Applications 9,11-Didehydrooestriol (Estriol EP Impurity A) is an impurity of Estriol (E888960), a metabolite of Estradiol (E888000). An estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).<br>References Marrian, et al.: Biochem. J., 23,1090 (1929), Huffman, et al.: J. Biol. Chem., 169, 167 (1947),<br></p>Formula:C18H22O3Color and Shape:Off-WhiteMolecular weight:286.372-Hydroxymethylene Ethisterone
CAS:Controlled Product<p>Applications A derivative of Danazol (D145000).<br>References Manson, A.J., et al.: J. Med. Chem., 6, 1 (1963), Jordan, V.C., et al.: Endocrinology, 124, 1717 (1989),<br></p>Formula:C22H28O3Color and Shape:NeatMolecular weight:340.4610β-Peroxy ∆4-Tibolone
CAS:Controlled Product<p>Applications ∆4-Tibolone derivative. A potential impurity of ∆4-Tibolone (T437505).<br>References Grunwell, J.F., et al.: Steroids, 27, 759 (1976),<br></p>Formula:C21H28O4Color and Shape:NeatMolecular weight:344.44(3Z)-17-Desacetyl Norgestimate
CAS:Controlled Product<p>Applications A metabolite of Norgestimate. Note- The oxime isomerizes when: 1) Heated in any solvent or heating the crystalline form 2) Dissolved in MeOH at room temperature very quickly 3) Dissolved in acetone or CHCl3 at room temperature in a couple of hours at room temperature4) In EtOAc or EtOAc/isooctane over a couple of days at RT. It is stable in the crystalline form.<br>References Phillips, A., et al.: Steroids, 55, 373 (1990)<br></p>Formula:C21H29NO2Color and Shape:White To BeigeMolecular weight:327.46E,E-Dienestrol
CAS:Controlled Product<p>Applications A metabolite of Diethylstilbestrol.<br>References Liehr, J.G., et al.: Steroids, 40, 713 (1982),<br></p>Formula:C18H18O2Color and Shape:NeatMolecular weight:266.33Fulvestrant 3-β-D-Glucuronide
CAS:Controlled Product<p>Applications A metabolite of Fulvestrant (F862500).<br>References Rao, P., et al.: J. Steroid Biochem., 25, 417 (1986), Wakeling, A., et al.: J. Steroid Biochem. Mol. Biol., 43, 173 (1992), DeFriend, D., et al.: Cancer Res., 54, 408 (1994),<br></p>Formula:C38H55F5O9SColor and Shape:Off-White To Light BeigeMolecular weight:782.8916-Epiestriol
CAS:Controlled Product<p>Impurity Estriol EP Impurity F<br>Applications 16-Epiestriol (Estriol EP Impurity F) is a metabolite of Estradiol.<br>References Marrian, B., et al.: Biochem. J., 59, 136 (1955), Dietel, M., et al.: Cancer Res., 50, 6100 (1990), Schumacher, G., et al.: Clin. Cancer Res., 5, 493 (1999), Robert, J., et al.: J. Med. Chem., 46, 4805 (2003),<br></p>Formula:C18H24O3Color and Shape:WhiteMolecular weight:288.38a-Acetyl Digoxin
CAS:Controlled Product<p>Applications Digoxin derivative, a cardiotonic glycosides steroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yoshida, F., et al.: J. Med. Chem., 43, 2575 ( 2000), Turner, J., et al.: Pharm. Res., 21, 68 (2004), Wang, J., et al.: Anal. Chim. Acta, 601, 156 (2007),<br></p>Formula:C43H66O15Color and Shape:NeatMolecular weight:822.9817-O-Acetyl-6-methylprednisolone
CAS:Controlled ProductFormula:C24H32O6Color and Shape:NeatMolecular weight:416.51Dihydro Dutasteride
CAS:<p>Applications Dihydro Dutasteride is an impurity arose during the process development of Dutasteride (D735000).<br>References Solomons, W., et al.: J. Pharma. Sci., 63, 19 (1974), Rasmusson, G., et al.: J. Med. Chem., 29, 2298 (1986),<br></p>Formula:C27H32F6N2O2Color and Shape:NeatMolecular weight:530.55Estrone sulfate sodium
CAS:<p>Estrone sulfate sodium, an inactive estrogen ester, transforms into estrone via steroid sulfatase. It's studied for targeting polypeptide transporters.</p>Formula:C18H21NaO5SPurity:98% - 99.83%Color and Shape:SolidMolecular weight:372.41Estrone 3-O-Sulfamate
CAS:Controlled Product<p>Applications A potent inhibitor of estrone sulfatase. Inhibits estrone sulfatase >99% at 0.1uM in intact MCF-7 cells, IC50=65pM.<br>References Woo, L.W., et al.: J. Med. Chem., 41, 1068 (1998)<br></p>Formula:C18H23NO4SColor and Shape:NeatMolecular weight:349.44Algestone
CAS:Controlled Product<p>Applications A pregnane steroid, its acetonide is used as anti-inflammatory drug (topical) and combination with enanthate as injectable contraceptive.<br>References Hydorn, A., et al.: Steroids, 3, 493 (1964), Plesner, R., et al.: Acta Endorcinol., 61, 494 (1969),<br></p>Formula:C21H30O4Color and Shape:NeatMolecular weight:346.46Didemethyl Mifepristone
CAS:Controlled Product<p>Applications A metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Formula:C27H31NO2Color and Shape:NeatMolecular weight:401.54(6a,11b)-17,21-Bis(acetyloxy)-6,9-difluoro-11-hydroxy-pregna-1,4-diene-3,20-dione
CAS:Controlled ProductFormula:C25H30F2O7Color and Shape:NeatMolecular weight:480.55-Oxo Atorvastatin
CAS:<p>Applications Atorvastatin Derivative<br></p>Formula:C33H33FN2O5Color and Shape:NeatMolecular weight:556.62(Z)-Guggulsterone
CAS:Controlled Product<p>Applications (Z)-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent.<br>References Yang, D. et al.: J. Lipid Res., 53, 529 (2012); El-Mekkawy, S. et al.: Nat. Prod. Res., 27, 146 (2013);<br></p>Formula:C21H28O2Color and Shape:NeatMolecular weight:312.45(16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione
CAS:Controlled Product<p>Impurity Betamethasone EP Impurity C<br>Applications (16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione (Betamethasone EP Impurity C) is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient.<br>References Reeves, E.K.M., et al.: Bioorg., Med. Chem., 21, 2241 (2013), Xiong, Y., et al.: J. Pharm. Biomed. Anal., 49, 646 (2009)<br></p>Formula:C22H28O4Color and Shape:NeatMolecular weight:356.46Betamethasone 21-Valerate
CAS:<p>Impurity Betamethasone Valerate EP Impurity E<br>Applications Betamethasone 21-Valerate (Betamethasone Valerate EP Impurity E) is an isomeric impurity of Betamethasone 17-Valerate (B327075), as an corticosteroid. Betamethasone 21-Valerate was generated in the stress study of the active drug Betamethasone 17-Valerate (B327075).<br>References Caron, J.C., et al.: J. Pharmaceut. Sci., 73, 1703 (1984); Stouch, T.R., et al.: J. Med. Chem., 29, 2125 (1986);<br></p>Formula:C27H37FO6Color and Shape:WhiteMolecular weight:476.583α,5β-Tetrahydro Norgestrel
CAS:Controlled Product<p>Applications The major metabolite of the progestational agent Norgestrel (N689500).<br>References DeJongh, D.C. et al.: Steroids, 11, 649 (1968); Uniyal, J.P. et al.: Acta Endocrinol., 84, 155 (1977); Sisenwine, S.F. et al.: Drug Metab. Disp., 7, 1 (1979);<br></p>Formula:C21H32O2Color and Shape:NeatMolecular weight:316.48Desonide-21-aldehyde Hydrate
Controlled ProductFormula:C24H32O7Color and Shape:White To Light YellowMolecular weight:432.5077β-Spironolactone
CAS:Controlled Product<p>Impurity Spironolactone EP Impurity E<br>Applications 7β-Spironolactone (Spironolactone EP Impurity E) is the 7β-isomer of Spironolactone (S683000). It binds effectively to human plasma proteins.<br>References Chien, Y.W. et al.: J. Pharmac. Sci., 65, 1337 (1976);<br></p>Formula:C24H32O4SColor and Shape:NeatMolecular weight:416.57Dihydrodigoxin (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Dihydrodigoxin is a cardioinactive metabolite of Digoxin (D446575) that gets excreted in the urine after Digoxin administration in humans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Clark, D.R., et al.: Drug Metab. Dispos., 2, 148 (1974); Reuning, R.H., et al.: Drug Metab. Dispos., 13, 51 (1985); Butler, V.P., et al.: Pharmacology, 221, 123 (1982)<br></p>Formula:C41H66O14Color and Shape:NeatMolecular weight:782.95Norgestimate
CAS:Controlled Product<p>Applications Progestogen. In combination with estrogen as oral contraceptive.<br>References Hahn, D.W., et al.: Contraception, 16, 541 (1977), Weintraub, H.S., et al.: J. Pharm. Sci., 67, 1406 (1978),<br></p>Formula:C23H31NO3Color and Shape:White SolidMolecular weight:369.50
