Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4949 products of "Steroids and Derivatives"
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Eplerenone Hydroxyacid Potassium Salt
CAS:Controlled Product<p>Applications A metabolite of Eplerenone. Used in combination therapy for treatment of cardiovascular disorders.<br>References Staessen, J., et al.: J. Endocrinol., 91, 457 (1981), de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), MacFadyen, R., et al.: Cardiovasc. Res., 35, 30 (1997),<br></p>Formula:C24H31O7·KColor and Shape:Off-White To Light YellowMolecular weight:470.6017-Hydroxy-3,11-dioxo-androsta-1,4-diene-17β-carboxylic Acid
Controlled Product<p>Applications 17-Hydroxy-3,11-dioxo-androsta-1,4-diene-17β-carboxylic Acid is an intermediate used to prepare (11β,17α)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-androsta-1,4-diene-17-carboxylic acid (E890570) which is a derivative of Loteprednol Etabonate (L471400), an ophthalmic corticosteroid.<br>References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)<br></p>Formula:C20H24O5Color and Shape:NeatMolecular weight:344.4017-Hydroxy Pregnenolone
CAS:Controlled Product<p>Applications 17-Hydroxy Pregnenolone, is a metabolite of Pregnenolone (P712200).<br>References Kramer, R., et al.: J. Steroid Biochemi., 18, 715 (1983), Hiwatashi, A., et al.: J. Biochem., 98, 619 (1985), Eiichi, T., et al.: J. Pharmacol. Sci., 95, 140 (2004),<br></p>Formula:C21H32O3Color and Shape:White To Off-WhiteMolecular weight:332.48(E)-Betamethasone-∆17,20 21-Aldehyde
CAS:Formula:C22H27FO4Color and Shape:NeatMolecular weight:374.45(11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:<p>Applications (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, can be used for the synthesis of Calicoferol E, a vitamin D3 analogues.<br>References Vir Singh, T., et al.: ARKAT USA, INc., (2002);<br></p>Formula:C22H28O5Color and Shape:White To Light RedMolecular weight:372.4517β-Estradiol
CAS:Controlled Product<p>Impurity Ethinylestradiol EP Impurity D<br>Applications 17b-Estradiol is the major estrogen (1) secreted by the premenopausal ovary (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.<br></p>Formula:C18H24O2Color and Shape:NeatMolecular weight:272.38Testosterone 17-Isobutyrate
CAS:Controlled Product<p>Applications Testosterone ester.<br>References Zarzycki, P., et al.: Anal. Bioanal. Chem., 391, 2219 (2008), Talarovicova, A., et al.: Hormon. Behav., 55, 235 (2009),<br></p>Formula:C23H34O3Color and Shape:Off-WhiteMolecular weight:358.51Flurandrenolide
CAS:Controlled Product<p>Applications Glucocorticoid; antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Formula:C24H33FO6Color and Shape:NeatMolecular weight:436.51Dutasteride β-Dimer
CAS:Controlled Product<p>Applications Dutasteride β-Dimer is a dimer impurity of Dutasteride (D735000); a dual inhibitor of 5α-reductase isoenzymes type 1 and 2. Dutasteride is structurally related to Finasteride (F342000) and is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995); Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999); Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Formula:C46H55F6N3O4Color and Shape:NeatMolecular weight:827.94Lynestrenol
CAS:Controlled Product<p>Applications Lynestrenol is an orally available progestogen hormone used in contraception to avoid hereditary angiodema as well as in treatment of ischemic stroke.<br>References Saule, C. et al.: Clin. Exp. Allergy, 43, 475 (2013); Beraki, S. et al.: PLoS One., 8, e69233 (2013);<br></p>Formula:C20H28OColor and Shape:NeatMolecular weight:284.44Hydroxy Flutamide-d6
CAS:Controlled ProductFormula:C11H5D6F3N2O4Color and Shape:Light Yellow SolidMolecular weight:298.254-Hydroxy Atorvastatin-d5 Hemicalcium Salt
CAS:Controlled Product<p>Applications di(4-Hydroxy Atorvastatin-d5) Calcium Salt is a labeled metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Formula:C66H58D10CaF2N4O12Color and Shape:Beige SolidMolecular weight:1197.44-Pregnen-17α, 20α-diol-3-one
CAS:Controlled ProductFormula:C21H32O3Color and Shape:NeatMolecular weight:332.4811a-Hydroxy Canrenone
CAS:Controlled Product<p>Applications 11α-Hydroxy Canrenone is the key intermediate in the synthesis of Eplerenone, a cardiovascular drug. Canrenone was biotransformed into 11α-Hydroxycanrenone by Aspergillus ochraceus SIT34205.<br>References Luetscher, J., et al.: J. Clin. Invest., 29, 1576 (1950), Gaunt, R., et al.: J. Clin. Endocrinol. Metab., 15, 621 (1955), McMahon, E., et al.: Curr. Opin. Pharm., 1, 190 (2001), McMahon, E., et al.: Curr. Pharm. Des., 9, 1065 (2003),<br></p>Formula:C22H28O4Color and Shape:NeatMolecular weight:356.46Aldosterone
CAS:<p>Applications Aldosterone is an adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Biologically active aldosterone isomer; a mineralocorticoid produced by the adrenal cortex that induces urinary excretion of K+ and renal reabsorptioon of Na+. Exists as an equilibrium mixture of the aldehyde and the hemiacetal.<br>References Simpson, et al.: Experienta, 9, 333 (1953), Morel, A., et al.: Nature, 356, 523 (1992), Arima, S., et al.: Clin. Exp. Nephrol., 7, 172 (2003), Hirasawa, A., et al.: Eur. J. Pharmacol., 267, 71 (1994), Hiroyama, M., et al.: Mol. Endocrinol., 21, 247 (2007),<br></p>Formula:C21H28O5Color and Shape:White To Off-WhiteMolecular weight:360.4417β-Hydroxy Exemestane-d3
CAS:Controlled Product<p>Applications A labelled metabolite of Exemestane; exerts biological effects as an androgen.<br>References Howell, A., et al.: Lancet, 365, 60 (2005), Goss, P., et al.: Clin. Cancer Res., 10, 5717 (2004), Buzdar, A., et al.: Lancet Oncol., 7, 633 (2006), Coates, A., et al.: J. Clin. Oncol., 25, 486 (2007), Jordan, V., et al.: Steroids, 72, 7 (2007),<br></p>Formula:C20H23D3O2Color and Shape:NeatMolecular weight:301.44Dexamethasone Acid Ethyl Ester
CAS:<p>Applications Dexamethasone Acid Ethyl Ester is a derivative of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Formula:C23H31FO5Color and Shape:Off-WhiteMolecular weight:406.49δ4-Androstene-3β,17β-diol
CAS:Controlled Product<p>Applications A metabolite of Testosterone (T155000).<br>References Janer, G., et al.: Aquat. Toxicol., 75, 32 ( 2005), Lavado, R., et al.: Steroids, 71, 489 (2006),<br></p>Formula:C19H30O2Color and Shape:NeatMolecular weight:290.4416-Epiestriol, Ultra Pure (contains less than 0.3% Estriol)
CAS:Controlled ProductFormula:C18H24O3Color and Shape:NeatMolecular weight:288.38
