Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4948 products of "Steroids and Derivatives"
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Deltamedrane
CAS:<p>Stability Hygroscopic<br>Applications Deltamedrane is an impurity in the synthesis of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);<br></p>Formula:C22H30O4Color and Shape:BeigeMolecular weight:358.47S-deacetyl spironolactone
CAS:<p>Applications A metabolite of Spironolactone.<br>References Morris, R., et al.: Eur. J. Clin. Pharmacol., 34, 233 (1988), Dasgupta, A., et al.: Am. J. Clin. Pathol., 111, 406 (1999)<br></p>Formula:C22H30O3SColor and Shape:NeatMolecular weight:374.54D-(-)-Norgestrel 17-Acetate
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications D-(-)-Norgestrel 17-Acetate is an impurity of Norgestrel (N689500), progestational and ovulation inhibiting steroid.<br>References Sonneveld, E., et al.: Toxicol. Sci., 89, 173 (2006); Sopirak, A.M., et al.: Anal. Profiles Drug Subs., 4, 294 (1975), Dunson, T.R., et al.: Contraception, 48, 109 (1993),<br></p>Formula:C23H30O3Color and Shape:NeatMolecular weight:354.48Ciclesonide
CAS:Controlled Product<p>Applications A glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References Fukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001),<br></p>Formula:C32H44O7Color and Shape:White To Off-WhiteMolecular weight:540.69Secalciferol
CAS:Controlled Product<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of Vitamin D, a possibly anti-inflammatory steroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Boyan, B., et al.: Steroids, 66, 363 (2001), Holick, M., et al.: J. Cell Biochem., 88, 296 (2003), Vogeser, M., et al.: Clin. Chem., 50, 1415 (2004), Singh, R., et al.: J. Clin. Endocrinol. Metab., 91, 3055 (2006),<br></p>Formula:C27H44O3Color and Shape:NeatMolecular weight:416.6416-Keto 17β-Estradiol-d5 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Estradiol (E888000).<br>References Ball, P., et al.: Steroids, 33, 563 (1979), Wong, T., et al.: Clin. Chem., 38, 1830 (1992), Xu, X., et al.: J. Clin. Endocrinol. Metab., 84, 3914 (1999), Todorovic, R., et al.: Carcinogenesis, 22, 905 (2001), Travis, R., et al.: Breast Cancer Res., 5, 239 (2003),<br></p>Formula:C18H17D5O3Color and Shape:NeatMolecular weight:291.417-epi-Testosterone-d3
CAS:Controlled Product<p>Applications 17-epi-Testosterone-d3 is the labelled analog of 17-epi-Testosterone.Testosterone (T155000) and epitestosterone (T155005) are endogenous steroids that differ in the configuration of the hydroxyl-bearing carbon at C-17. Testosterone is the predominant male sex hormone, whereas the role of epitestosterone is largely unclear. In humans, both androgens are excreted mainly as glucuronide conjugates.<br>References Wudy, S., et al.: Steroids, 66, 759 (2001), Kootstra, P., et al.: Anal. Chim. Acta., 586, 82 (2007), Sten, T., et al.: Drug Metab. Dispos., 37, 417 (2009),<br></p>Formula:C192H3H25O2Color and Shape:NeatMolecular weight:291.446α-Hydroxy Progesterone (>80%)
CAS:Controlled ProductFormula:C21H30O3Purity:>80%Color and Shape:NeatMolecular weight:330.4616a-Methyl Prednisolone
CAS:Controlled Product<p>Applications 16α-Methylprednisolone is the 16α-Methyl analogue of Prednisolone (P703740). 16α-Methylprednisolone is an anti-inflammatory corticosteroid.<br>References Biju, P. et al.: Bioorg. Med. Chem. Lett., 22, 1086 (2012); Dausse, J.P. et al.: Mol. Pharmacol., 13, 948 (1977):<br></p>Formula:C22H30O5Color and Shape:NeatMolecular weight:374.4722b-Hydroxy Cholesterol
CAS:Controlled Product<p>Applications The 22S-metabolite of Cholesterol (C432501). 22-Hydroxycholesterol inhibits chemokine receptor activity.<br>References Samson, M., et al.: J. Biol. Chem., 272, 24934 (1997), Mackay, C., et al.: Nature Immunol., 2, 95 (2001), Navenot, J., et al.: J. Mol. Biol., 313, 1181 (2001),<br></p>Formula:C27H46O2Color and Shape:Off White SolidMolecular weight:402.65Triamcinolone Furetonide
CAS:Controlled ProductFormula:C33H35FO8Color and Shape:NeatMolecular weight:578.62Flurandrenolone Acetate
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity G<br>Applications Flurandrenolone Acetate, is the derivative of Flurandrenolide (F598650), which is a Glucocorticoid, used as an antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Formula:C26H35FO7Color and Shape:NeatMolecular weight:478.55Dienogest-d8 (major)
CAS:Controlled Product<p>Applications Dienogest-d8 (major) is labelled derivative of 19-Nortestosterone. It is used in combination with estrogen as oral contraceptive.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998)<br></p>Formula:C20H17D8NO2Color and Shape:Light YellowMolecular weight:319.47Paricalcitol
CAS:Controlled Product<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Synthetic analog of vitamin D. Antihyperparathyroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sidek, H., et al.: Biochim. Biophys. Acta, 801, 26 (1984), Ciftci, M., et al.: J. Pharmacol., 54, 275 (2002),<br></p>Formula:C27H44O3Color and Shape:NeatMolecular weight:416.64Testosterone Sulfate-d3 Triethylamine Salt
CAS:Controlled Product<p>Applications The labelled analogue of a metabolite of Testosterone (T155000). It is a urinary metabolite of Androstenedione (A637550) in patients with Addison's disease and also used as a marker in blood plasma for detection of prostate cancer.<br>References Lokhov, P.G. et al.: Metabolomics, 6, 156 (2010); Bonnaire, Y. et al.: J. Anal. Toxicol., 19, 175 (1995); Tamm, J. et al.: Steroids, 8, 659 (1966);<br></p>Formula:C25H40D3NO5SColor and Shape:Off-WhiteMolecular weight:472.717α-Hydroxy Progesterone
CAS:Controlled Product<p>Impurity Progesterone 17?-Hydroxy Impurity<br>Applications 17α-Hydroxy Progesterone is a metabolite of Progesterone (P755900). It was isolated from adrenal glands.<br>References Pfiffner, N., et al.: J. Biol. Chem., 132, 459 (1940), Florey, K., et al.: Anal. Profiles Drug Subs.,4, 209 (1975),<br></p>Formula:C21H30O3Color and Shape:Off-WhiteMolecular weight:330.4611-Deoxy Prednisolone
CAS:Controlled Product<p>Impurity Prednisolone EP Impurity J<br>Applications 11-Deoxy Prednisolone (Prednisolone EP Impurity J) is a Prednisolone (P703740) derivative as a corticosteroid.<br>References Kobayashi, Y., et al.: Biol. Pharm. Bull., 16, 1175 (1993), Ogata, M., et al.: J. Pharm. Sci., 87, 91 (1998), Hou, S., et al.: J. Pharm. Biomed. Anal., 24, 371 (2001),<br></p>Formula:C21H28O4Color and Shape:Light BrownMolecular weight:344.445β-Dihydrocortisol-d6
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 5β-Dihydrocortisol-d6 is an isotope labelled analog of 5β-Dihydrocortisol (D448595). 5β-Dihydrocortisol, is a derivative of Cortisol (H714615), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland.<br>References Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),<br></p>Formula:C21H26D6O5Color and Shape:NeatMolecular weight:370.51Betamethasone 17-Valerate
CAS:Controlled Product<p>Applications Betamethasone 17-Valerate is a corticosteroid with anti-inflammatory properties. Topical application of Betamethasone 17-Valerate has been shown to inhibit heat-induced vasodilatation in man.<br>References Banfi, S. et al.: Curr. Ther. Res., 19, 126 (1976); Ahluwalia, A. et al.: Br. J. Dermatol., 128, 45 (1993);<br></p>Formula:C27H37FO6Color and Shape:WhiteMolecular weight:476.5817β-Estradiol-d3 17-Acetate
CAS:Controlled Product<p>Applications Protected Estradiol.<br>References Miilunpohja, M., et al.: J. Steroid Biochem. Mol. Biol., 100, 59 (2006), Ikonomou, M., et al.: Environ. Toxicol. Chem., 27, 243 (2008),<br></p>Formula:C20H23D3O3Color and Shape:NeatMolecular weight:317.44Dienestrol
CAS:<p>Applications Dienestrol is a metabolite of Diethylstilbestrol, a non-steroidal synthetic estrogen derivative.<br>References Liehr, J.G., et al.: Steroids, 40, 713 (1982); Yearley, E. et al.: J. Mol. Struct., 890, 240 (2008);<br></p>Formula:C18H18O2Color and Shape:NeatMolecular weight:266.335α-Pregnane-3β,20(S)-diol
CAS:Controlled Product<p>Applications 5α-Pregnane-3β,20(S)-diol, is a metabolite of Progesterone (P755900).<br>References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),<br></p>Formula:C21H36O2Color and Shape:NeatMolecular weight:320.511,2-Dihydrobudesonide (Mixture of diastereomers)
CAS:Controlled Product<p>Impurity Budesonide EP Impurity G<br>Applications 1,2-Dehydrobudesonide (Budesonide EP Impurity G) is an impurity in the synthesis of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),<br></p>Formula:C25H36O6Color and Shape:NeatMolecular weight:432.55Budesonide-d6
CAS:Controlled Product<p>Applications Labelled Budesonide, a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),<br></p>Formula:C25H28D6O6Color and Shape:NeatMolecular weight:436.5717α-Hydroxy Progesterone-d8
CAS:Controlled Product<p>Applications Labelled 17α-Hydroxyprogesterone (H952330). 17α-Hydroxy Progesterone is a metabolite of Progesterone. It was isolated from adrenal glands.<br>References Pfiffner, N., et al.: J. Biol. Chem., 132, 459 (1940), Florey, K., et al.: Anal. Profiles Drug Subs.,4, 209 (1975),<br></p>Formula:C212H8H22O3Color and Shape:Off-WhiteMolecular weight:338.5117β-Estradiol-16,16,17-d3 3-Benzoate
CAS:Controlled Product<p>Applications 17beta-Estradiol-16,16,17-d3 3-Benzoate (CAS# 1192354-74-7) is a useful isotopically labeled research compound.<br></p>Formula:C25H25D3O3Color and Shape:NeatMolecular weight:379.514-Hydroxy Estrone
CAS:Controlled ProductFormula:C18H22O3Color and Shape:Light Brown SolidMolecular weight:286.37Estradiol-13C2 17-Benzoate
CAS:<p>Applications Estradiol-13C2 17-Benzoate is an intermediate in the synthesis of 17β-Estradiol-13C2 (E888003). Isotope labelled 17β-Estradiol (E888000) is the major estrogen (1) secreted by the premenopausal ovary (2).<br></p>Formula:C2313C2H28O3Purity:>90%Color and Shape:NeatMolecular weight:378.47Fluocinolone Acetonide-21-aldehyde
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity D<br>Stability Hygroscopic<br>Applications Fluocinolone acetonide-21-aldehyde, is a derivative of Fluocinolone Acetonide (F455800), which is a Corticosteroid, used in dermatology to reduce skin inflammation and relieve itching.<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Formula:C24H28F2O6Color and Shape:White To Light YellowMolecular weight:450.47Aldosterone-d7 (Major)
CAS:Controlled ProductFormula:C21H21D7O5Color and Shape:NeatMolecular weight:367.4916α-Homo 2-(Hydroxymethyl)betamethasone
CAS:Controlled ProductFormula:C22H29FO5Color and Shape:NeatMolecular weight:392.461Fluvastatin
CAS:<p>Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent cardiovascular disease.</p>Formula:C24H26FNO4Purity:98.94%Color and Shape:SolidMolecular weight:411.47Testosterone Hexanoate
CAS:Controlled ProductFormula:C25H38O3Color and Shape:NeatMolecular weight:386.574-Hydroxy Atorvastatin-d5 Hemicalcium Salt
CAS:Controlled Product<p>Applications di(4-Hydroxy Atorvastatin-d5) Calcium Salt is a labeled metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Formula:C66H58D10CaF2N4O12Color and Shape:Beige SolidMolecular weight:1197.45,6-trans-Vitamin D3, ~90%
CAS:Controlled Product<p>Impurity Cholecalciferol EP Impurity A<br>Stability Light Sensitive, Temperature Sensitive<br>Applications 5,6-trans-Vitamin D3 (Cholecalciferol EP Impurity A) is the major photoisomer of Vitamin D3 analog, as an impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bikle, D., et al.: Biochemistry, 25, 1545 (1986), Webb, A., et al.: J. Clin. Endocrinol. Metab., 68, 882 (1989), Baran, D., et al.: J. Cell Biochem., 50, 124 (1992), Tian, X., et al.: J. Biol. Chem., 268, 14888 (1993),<br></p>Formula:C27H44OPurity:~90%Color and Shape:White To Light YellowMolecular weight:384.64β-Methyl Digoxin
CAS:<p>Applications Cardiotonic. Obtained by the O-methylation of Digoxin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hunter, J., et al.: J. Biol. Chem., 268, 14991 (1993), Greiner, B., et al.: J. Clin. Invest., 104, 147 (1999), Jun, A., et al.: J. Pharm.Pharm. Sci., 4, 263 (2001), Sugiyama, D., et al.: Drug Metab. Dispos., 30, 220 (2002),<br></p>Formula:C42H66O14Color and Shape:NeatMolecular weight:794.97Difluprednate
CAS:Controlled Product<p>Applications A corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.<br>References Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002), Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003), Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005),<br></p>Formula:C27H34F2O7Color and Shape:WhiteMolecular weight:508.55δ4-Androstene-3β,17β-diol
CAS:Controlled Product<p>Applications A metabolite of Testosterone (T155000).<br>References Janer, G., et al.: Aquat. Toxicol., 75, 32 ( 2005), Lavado, R., et al.: Steroids, 71, 489 (2006),<br></p>Formula:C19H30O2Color and Shape:NeatMolecular weight:290.44(17β)-N-(1,1-Dimethylethyl)-3-oxoandrost-4-ene-17-carboxamide
CAS:Controlled ProductFormula:C24H37NO2Color and Shape:Off-WhiteMolecular weight:371.5617β-Estradiol 3-O-Sulfate Sodium
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 17β-Estradiol 3-O-Sulfate is a neuroactive steroid used in the studies of human recombinant p1 γ-aminobutyric acid type C (GABAC) recptors.<br>References Li, W.J., et al.: J. Pharmacol. Exp. Therp., 323, 236 (2007); Schneider, C., et al.: Steroids., 69, 245 (2004);<br></p>Formula:C18H23O5S·NaColor and Shape:NeatMolecular weight:374.43Diethylstilbestrol Dipropionate
CAS:<p>Applications Diethylstilbestrol dipropionate<br></p>Formula:C24H28O4Color and Shape:White To Off-WhiteMolecular weight:380.48Lathosterol
CAS:<p>Applications A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other.<br>References Chyou, P., et al.: Age Ageing, 29, 69 (2000), Schatz, I., et al.: Lancet, 358, 351 (2001), Bjorkman, M., et al.: Eur. J. Endocrinol., 158, 749 (2008),<br></p>Formula:C27H46OColor and Shape:White To Off-WhiteMolecular weight:386.6521-Dehydro Dexamethasone Hydrate
CAS:Formula:C22H27FO5·H2OColor and Shape:White To Light YellowMolecular weight:408.462,3-Dichloro-5,6-dicyanobenzoquinone
CAS:<p>Applications An oxidizing agent, especially in steroid synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C8Cl2N2O2Color and Shape:NeatMolecular weight:227.0Finasteride Carboxylic Acid
CAS:Controlled ProductFormula:C23H34N2O4Color and Shape:Light Yellow SolidMolecular weight:402.53(6a,11b,16b)-6-Bromo-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:<p>Applications (6α,11β,16β)-6-Bromo-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione is a derivative of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Formula:C22H28BrFO5Color and Shape:NeatMolecular weight:471.361,2-Dihydro Dexamethasone
CAS:<p>Applications A derivatives of Dexamethasone (D298800), an analog of cortical hormones.<br>References Giesen, E.M., et al.: Molec. Cell. Endocrinol., 22, 153 (1981),<br></p>Formula:C22H31FO5Color and Shape:White To Light BeigeMolecular weight:394.48Gestrinone
CAS:Controlled Product<p>Applications Gestrinone is a Steroidal antiestrogen, antiprogestogen, analog of Norgestrienone. Antigonadotropin.Controlled substance.<br>References Azadian-Boulanger, G., et al.: Am. J. Obstet. Gynecol., 125, 1049 (1976), Thomas, E.J., et al.: Br. Med. J., 294, 272 (1987), Coutinho, E.M., et al.: Fertil. Steril., 49, 418 (1988),<br></p>Formula:C21H24O2Color and Shape:NeatMolecular weight:308.40
