Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4949 products of "Steroids and Derivatives"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
a,a,a-Trifluorotoluene
CAS:Controlled Product<p>Applications α,α,α-Trifluorotoluene, is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skelly, P. D., et al.: Handbook for Critical Cleaning, 1, 191 (2011);<br></p>Formula:C7H5F3Color and Shape:ColourlessMolecular weight:146.11δ6-Fulvestrant
CAS:Controlled Product<p>Impurity Fulvestrant Impurity E;<br>Applications Fulvestrant (F862500) impurity E.<br></p>Formula:C32H45F5O3SColor and Shape:NeatMolecular weight:604.756β-Hydroxymethylandrosta-1,4-diene-3,17-dione
CAS:Controlled ProductFormula:C20H26O3Color and Shape:White To Off-WhiteMolecular weight:314.4225-Hydroxy Vitamin D3 3,3'-Biotinylaminopropyl Ether
CAS:<p>Applications Vitamin D3 (V676045) analog.<br>References Roy, A., et al.: Steroids, 60, 530 (1995);<br></p>Formula:C40H65N3O4SColor and Shape:NeatMolecular weight:684.0318-Methyl Ethynyl Estradiol
CAS:Controlled ProductFormula:C21H26O2Color and Shape:NeatMolecular weight:310.4299Deflazacort-d3 (Major)
CAS:Controlled ProductFormula:C25H28D3NO6Color and Shape:NeatMolecular weight:444.54Dexamethasone Acetate Impurity E
CAS:<p>Applications Dexamethasone Acetate Impurity E is a pregn-4-ene derivative used in the preparation of antiallergic and antiinflammatory drugs.<br>References Nedelec, L., et al.: Ger. Offen. (1978)<br></p>Formula:C24H33FO6Color and Shape:NeatMolecular weight:436.51Atorvastatin-d5 tert-Butyl Ester
CAS:Controlled Product<p>Applications Atorvastatin-d5 tert-Butyl Ester is the labeled analogue of Atorvastatin tert-Butyl Ester (A791740), an impurity arising in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Formula:C37H38D5FN2O5Color and Shape:NeatMolecular weight:619.78Ciclesonide-d7
CAS:Controlled Product<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References ukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Formula:C32H37D7O7Color and Shape:NeatMolecular weight:547.7313β-Ethyl-11-methylenegon-4-en-17-one
CAS:Controlled Product<p>Applications Desogestrel intermediate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bergink, E., et al.: J. Steroid Biochem., 14, 175 (1981), Phillips, A., et al.: Contraception, 36, 181 (1987)<br></p>Formula:C20H28OColor and Shape:NeatMolecular weight:284.44Fluticasone-d3 17β-Carboxylic Acid
CAS:Controlled ProductFormula:C21H23D3F2O5Color and Shape:NeatMolecular weight:399.44(9β,11β,16α)-9,11-Epoxy-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
CAS:Controlled Product<p>Applications Glucocorticoid.<br></p>Formula:C22H28O4Color and Shape:NeatMolecular weight:356.4617a-Hydroxy-17a-methyl-D-homoandrost-4-ene-3,17-dione
CAS:Controlled ProductFormula:C21H30O3Color and Shape:NeatMolecular weight:330.46Ulipristal
CAS:Controlled Product<p>Applications Ulipristal is a selective progesterone receptor modulator. Ulipristal is used as an emergency contraceptive.<br>References Gronemeijer, H., et al.: J. Steroid Biochem., 40, 271 (1991), Spitz, I., et al.: Contraception, 48, 403 (1993), Conneely, O., et al.: Steroids, 68, 771 (2003), Chwalisz, K., et al.: Endocr. Rev., 26, 423 (2005),<br></p>Formula:C28H35NO3Color and Shape:NeatMolecular weight:433.586α-Hydroxy Budesonide
CAS:Controlled ProductFormula:C26H34O7Color and Shape:NeatMolecular weight:458.543β,5α-Tetrahydrodeoxycorticosterone
CAS:<p>Applications 3β,5α-Tetrahydrodeoxycorticosterone is a novel derivative of the steroid Dehydroepiandrosterone (DHEA), a known uncompetitive inhibitor of Glucose 6-Phosphate Dehydrogenase (G6PD). Studies have shown that 3β,5α-Tetrahydrodeoxycorticosterone may have potential function in the modulation of calcium and GABAA-gated chloride channel currents found in rat and guinea-pig neurons.<br>References Hamilton, N.M., et al.: J. Medn. Chem., 55, 4431 (2012); Ffench, M., et al.: Steriods., 64, 76 (1999);<br></p>Formula:C21H34O3Color and Shape:White To Off-WhiteMolecular weight:334.49Travoprost 13,14-Epoxide (Mixture of Diastereomers)
Controlled Product<p>Stability Temperature Sensitive<br>Applications An epoxy impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600).<br></p>Formula:C26H35F3O7Color and Shape:NeatMolecular weight:516.35Betamethasone 21-Acetate-d3
CAS:Controlled Product<p>Applications Betamethasone 21-Acetate-d3, is the labeled analogue of Betamethasone 21-Acetate (B327025), which is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.<br>References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003), Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007),<br></p>Formula:C24H28D3FO6Color and Shape:NeatMolecular weight:437.52Desisobutyryl Ciclesonide
CAS:Controlled Product<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Formula:C28H38O6Color and Shape:White To Off-WhiteMolecular weight:470.60N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
CAS:Controlled Product<p>Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)<br></p>Formula:C25H38N2O2Color and Shape:NeatMolecular weight:398.5817β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide
CAS:Controlled Product<p>Applications 17β-Hydroxy Exemestane 17-O-β-D-Glucuronide is the glucuronidated conjugate of the hydroxy metabolite of Exemestane (E957000).<br>References Sun, D. et al.: Pharmacogen. Genom., 20, 575 (2010);<br></p>Formula:C26H31D3O8Color and Shape:NeatMolecular weight:477.566-Keto Dexamethasone
Controlled Product<p>Applications 6-keto Dexamethasone, is an impurity of Dexamethasone, a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br></p>Formula:C22H27FO6Color and Shape:NeatMolecular weight:406.44Tasimelteon
CAS:<p>Applications Tasimelteon is a novel drug, used in the treatment of non-24 hour sleep-wake disorder. It helps to correct the circadian rhythm disorder often seen in patients who are visually impaired.<br>References Lahon, J. et al.: World. J. Pharm. Res., 3, 1521 (2014);<br></p>Formula:C15H19NO2Color and Shape:NeatMolecular weight:245.3169Atorvastatin Lactone Diepoxide(Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An Atorvastatin (A791750) derivative which have improved stability.<br></p>Formula:C33H33FN2O6Color and Shape:NeatMolecular weight:572.62(4S,trans)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:Controlled ProductFormula:C14H27NO4Color and Shape:NeatMolecular weight:273.376-Oxo Boldione
CAS:Controlled Product<p>Applications A derivative of Exemestane (E957000), a new aromatase inhibitor.<br>References Thompson, E., et al.: J. Biol. Chem., 249, 5364 (1974), Cole, P., et al.: J. Med. Chem., 33, 2933 (1990), Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Formula:C19H22O3Color and Shape:Off-White To Light YellowMolecular weight:298.38[1S-(1α,3aBeta,4β,7aAlpha)]-4-[2-(2,5-Dihydroxyphenyl)ethyl]octahydro-1-hydroxy-7a-methyl-5H-inden-5-one
CAS:Controlled ProductFormula:C18H24O4Color and Shape:NeatMolecular weight:304.38Prednicarbate
CAS:Controlled Product<p>Applications Topical anti-inflammatory agent. Glucocorticoid.<br>References Stache, U., et al.: Arzneim.-Forsch., 35, 1753 (1985),<br></p>Formula:C27H36O8Color and Shape:Off-WhiteMolecular weight:488.57Testosterone-16,16,17-d3 3-Phenylpropionate
CAS:Controlled Product<p>Applications Testosterone-16,16,17-d3 17-Phenylpropionate, is the labeled analogue of Testosterone 17-Phenylpropionate (T155150), a Testosterone ester being misused by athletes in an attempt to improve sports performance. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.<br>References Shackleton, C. H. L., et al.: Steroids, 62 (7), 523 (1997); Reid, I. R., et al.: Archives Internal Med., 156 (11), 1173 (1996);<br></p>Formula:C28H33D3O3Color and Shape:NeatMolecular weight:423.60Estradiol 17-Valerate-d9
CAS:Controlled Product<p>Applications Labelled Estradiol (E888000) derivative. An estrogen.<br>References Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987),<br></p>Formula:C23H23D9O3Color and Shape:NeatMolecular weight:365.55Estradiol 3-heptanoate
CAS:Controlled ProductFormula:C25H36O3Color and Shape:NeatMolecular weight:384.55Testosterone Undecanoate-d21
CAS:Controlled ProductFormula:C30H27D21O3Color and Shape:Off-WhiteMolecular weight:477.84(E/Z)-17-Deacetylnorgestimate
CAS:Controlled ProductFormula:C21H29NO2Color and Shape:NeatMolecular weight:327.46Betamethasone 17-Propionate 21-Mesylate
CAS:<p>Impurity Clobetasol Propionate EP Impurity I<br>Stability Hygroscopic<br>Applications Betamethasone 17-Propionate 21-Mesylate (Clobetasol Propionate EP Impurity I) is the 21-mesylate analogue of Betamethasone 17-Acetate (B327015) with antiinflammatory activity.<br>References Mitsukuchi, M. et al.: Chem. Pharm. Bull., 37, 3286 (1989);<br></p>Formula:C26H35FO8SColor and Shape:NeatMolecular weight:526.616b-Hydroxylevonorgestrel
CAS:<p>Impurity Levonorgestrel EP Impurity H<br>Applications 6β-Hydroxylevonorgestrel (Levonorgestrel EP Impurity H) is an impurity from the synthesis of Levonorgestrel (N689510), an oral contraceptive.<br>References Hu. S.H., et al.: Steroids., 63, 88 (1998); Nash, H.A., et al.: J. Pharma. Sci., 93, 2420 (2004); Choudhary, M.I., et al.: Natural. Prod. Res., 20, 1074 (2006);<br></p>Formula:C21H28O3Color and Shape:White To Light YellowMolecular weight:328.451-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one
CAS:Controlled Product<p>Applications 1-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one is an antioxidant and also has anti cancer effects on human breast cancer MCF-7 cells and Hep3B human hepatocellular carcinoma cells.<br>References Choi, Eun Jeong, et al.: Mol. Med. Rep., 9(1), 328-332 (2014);Choi, Eun Jeong, et al.: Onco.Lett., 6(6), 1784-1788 (2013);Choi, Eun Jeong, et al.: Inter. J.of Mol. Med., 31(3), 726-730 (2013)<br></p>Formula:C15H14O4Color and Shape:NeatMolecular weight:258.27Dexamethasone b-D-Glucuronide Sodium (>90%)
CAS:Controlled Product<p>Applications Sodium salt of Dexamethasone β-D-Glucuronide is a potential prodrug for colonic delivery of the antiinflammatory corticosteroid Dexamethasone.<br>References Fotsis, T., et al.: J. Steroid Biochem., 14, 457 (1981), Choi, M., et al.: Steroids, 65, 54 (2000); Haeberlin, B. et al.: Pharm Res., 10, 1553 (1993);<br></p>Formula:C28H36FNaO11Color and Shape:NeatMolecular weight:590.57rac 5-Keto Fluvastatin
CAS:<p>Rac5-Keto Fluvastatin is a synthetic, natural and custom synthesis drug product. It's CAS number is 1160169-39-0. Rac5-Keto Fluvastatin is a metabolite of fluvastatin. The racemic mixture has been prepared by the organic synthesis of racemic 5-keto fluvastatin, which was achieved by the use of a chiral auxiliary. Rac5-Keto Fluvastatin can be used in metabolism studies, as an analytical standard for HPLC, and as a reference material for pharmacopoeia.</p>Formula:C24H24FNO4Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:409.45 g/molAtorvastatin 3-deoxyhept-2-enoic acid
CAS:<p>Atorvastatin is a potent inhibitor of the enzyme HMG-CoA reductase, which is responsible for the conversion of HMG-CoA to mevalonate. This inhibition reduces the production of cholesterol and other lipids in the liver. Metabolism studies have shown that atorvastatin undergoes extensive presystemic metabolism by cytochrome P450 enzymes, primarily CYP3A4 and CYP2C9. The drug is converted to inactive metabolites that are eliminated primarily through renal excretion. Atorvastatin has not been found to inhibit any of the following: cytochrome P450 1A1/2, 2C8/9, 2D6, 2E1, 3A4/5 or glucuronidases.</p>Formula:C33H33FN2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:540.62 g/molDexamethasone Impurity A
<p>Impurity A is an impurity of the drug product, dexamethasone. The impurity is a natural metabolite of dexamethasone that is found in the urine of patients taking this medication. Impurity A is chemically identified using HPLC and its purity verified using GC-MS and LC-MS. This impurity can be used as a reference standard for analytical purposes and as an impurity standard for pharmacopoeia testing.</p>Formula:C22H29FO5Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:392.46 g/molAtorvastatinN-(3,5-dihydroxy-7-heptanoic acid)amide
CAS:<p>Atorvastatin is a synthetic drug product. It is a prodrug that is converted to its active form, atorvastatin acid, in the body. Atorvastatin is used for lowering blood cholesterol levels in people with hypercholesterolemia and reducing the risk of coronary heart disease. This drug has been shown to reduce the number of deaths from coronary heart disease by 30% after five years of use. Atorvastatin also reduces the risk of stroke and fatal or non-fatal heart attack by 20%.</p>Formula:C40H48FN3O8Purity:Min. 95%Molecular weight:717.82 g/molFluticasone furoate EP impurity E
CAS:<p>Fluticasone furoate EP impurity E is an analytical reference standard for pharmacopoeia and research. It is a synthetic fluticasone furoate EP impurity that has been custom synthesized for use as a high-purity, HPLC-grade standard. Fluticasone furoate EP impurity E is characterized by its natural origin and purity, making it appropriate for use in drug development and research. The CAS number for this product is 398454-97-2.</p>Formula:C25H31F3O5SPurity:Min. 95%Molecular weight:500.5 g/molFluorometholone δ 9,11
CAS:Controlled Product<p>Fluorometholone delta 9,11 is a drug product that is used as an analytical reference standard for the quantitative determination of impurities in drugs. It is a natural metabolite and impurity in synthetic drugs such as fluoroquinolones and corticosteroids. Fluorometholone delta 9,11 has been shown to be a substrate for CYP3A4 and P-glycoprotein. This drug has also been shown to have anti-inflammatory effects and may decrease the risk of infection by suppressing neutrophil function.</p>Formula:C22H28O3Purity:Min. 95%Molecular weight:340.46 g/molBIBB 515
CAS:<p>BIBB 515 inhibits OSC, reducing cholesterol in hamsters by up to 25% with specific dosing.</p>Formula:C22H21ClN2O2Purity:99.68%Color and Shape:SolidMolecular weight:380.87Calcipotriol monohydrate
CAS:<p>Calcipotriol monohydrate, a Vitamin D3 analog, binds well to the vitamin D receptor, used in psoriasis research.</p>Formula:C27H42O4Purity:99.95%Color and Shape:SolidMolecular weight:430.62Abiraterone dimer impurity
CAS:Controlled Product<p>Abiraterone dimer impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs. It is also a metabolite of abiraterone and has been detected in the urine of patients receiving the drug. Abiraterone dimer impurity is found in trace amounts in abiraterone acetate but its pharmacological significance is not known. This impurity has been detected in the urine of patients receiving abiraterone acetate therapy.</p>Formula:C43H57NO2Purity:Min. 95%Molecular weight:619.92 g/mol(3S,5R)-Atorvastatin calcium
CAS:<p>(3S,5R)-Atorvastatin calcium is an analytical standard for the drug atorvastatin. It has a purity of 99.9% and is manufactured in accordance with the requirements of the pharmacopoeia. The product is available as a white crystalline powder and is soluble in water, acetone, and ethanol. (3S,5R)-Atorvastatin calcium has been used in drug development and as an impurity standard for HPLC analysis. It also serves as a metabolite to characterize the production process of atorvastatin.</p>Formula:C66H68CaF2N4O10Purity:Min. 95%Molecular weight:1,155.34 g/molFluorometholone impurity 5
CAS:<p>Fluorometholone impurity 5 is a drug product that has been custom synthesized. It has not yet been assigned to a CAS number. This compound exhibits high purity and is an analytical grade. Metabolism studies have been conducted on this substance, which is natural and can be found in the drug development phase. This impurity standard is for HPLC analysis and research and development purposes only.</p>Purity:Min. 95%(3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt
CAS:<p>(3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt is an impurity standard for the drug product. It is a synthetic metabolite that binds to proteins and has been found in human urine. The chemical synthesis of (3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6 heptenoic acid sodium salt was performed using a high purity custom synthesis and high purity pharmacopoeia grade reagents.</p>Formula:C23H23FNNaO4Purity:Min. 95%Molecular weight:419.42 g/mol
![[1S-(1α,3aBeta,4β,7aAlpha)]-4-[2-(2,5-Dihydroxyphenyl)ethyl]octahydro-1-hydroxy-7a-methyl-5H-inden…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD458310.webp&w=3840&q=75)
![(3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIE23517.webp&w=3840&q=75)