Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4949 products of "Steroids and Derivatives"
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Desmosterol-d6
CAS:Controlled Product<p>Applications A labelled metabolite of Cholesterol (C432501).<br>References Marx, J., et al.: Science, 294, 508 (2001), Plosch, T., et al.: J. Biol. Chem., 277, 33870 (2002), Lund, E., et al.: J .Biol. Chem., 278, 22980 (2003),<br></p>Formula:C272H6H38OColor and Shape:NeatMolecular weight:390.67Testosterone Undecanoate-d3
CAS:Controlled Product<p>Applications A Labelled metabolite of Testosterone (T155000). It is a promising androgen for male hormonal contraception.CONTROLLED SUBSTANCE<br>References Glass, A., et al.: J. Clin. Endocrinol. Metab., 45, 1211 (1977), Behre, H., et al.: Eur. J. Endocrinol., 140, 414 (1999), Nieschlag, E., et al.: Steroids, 68, 965 (2003), Wang, C., et al.: J. Clin. Endocrinol. Metab., 91, 460 (2006),<br></p>Formula:C30H45D3O3Color and Shape:NeatMolecular weight:459.729,11-Didehydrooestriol
CAS:Controlled Product<p>Impurity Estriol EP Impurity A<br>Stability Hygroscopic<br>Applications 9,11-Didehydrooestriol (Estriol EP Impurity A) is an impurity of Estriol (E888960), a metabolite of Estradiol (E888000). An estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).<br>References Marrian, et al.: Biochem. J., 23,1090 (1929), Huffman, et al.: J. Biol. Chem., 169, 167 (1947),<br></p>Formula:C18H22O3Color and Shape:Off-WhiteMolecular weight:286.3716-Epiestriol
CAS:Controlled Product<p>Impurity Estriol EP Impurity F<br>Applications 16-Epiestriol (Estriol EP Impurity F) is a metabolite of Estradiol.<br>References Marrian, B., et al.: Biochem. J., 59, 136 (1955), Dietel, M., et al.: Cancer Res., 50, 6100 (1990), Schumacher, G., et al.: Clin. Cancer Res., 5, 493 (1999), Robert, J., et al.: J. Med. Chem., 46, 4805 (2003),<br></p>Formula:C18H24O3Color and Shape:WhiteMolecular weight:288.385-Oxo Atorvastatin
CAS:<p>Applications Atorvastatin Derivative<br></p>Formula:C33H33FN2O5Color and Shape:NeatMolecular weight:556.62(Z)-Guggulsterone
CAS:Controlled Product<p>Applications (Z)-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent.<br>References Yang, D. et al.: J. Lipid Res., 53, 529 (2012); El-Mekkawy, S. et al.: Nat. Prod. Res., 27, 146 (2013);<br></p>Formula:C21H28O2Color and Shape:NeatMolecular weight:312.45(16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione
CAS:Controlled Product<p>Impurity Betamethasone EP Impurity C<br>Applications (16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione (Betamethasone EP Impurity C) is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient.<br>References Reeves, E.K.M., et al.: Bioorg., Med. Chem., 21, 2241 (2013), Xiong, Y., et al.: J. Pharm. Biomed. Anal., 49, 646 (2009)<br></p>Formula:C22H28O4Color and Shape:NeatMolecular weight:356.46Betamethasone 21-Valerate
CAS:<p>Impurity Betamethasone Valerate EP Impurity E<br>Applications Betamethasone 21-Valerate (Betamethasone Valerate EP Impurity E) is an isomeric impurity of Betamethasone 17-Valerate (B327075), as an corticosteroid. Betamethasone 21-Valerate was generated in the stress study of the active drug Betamethasone 17-Valerate (B327075).<br>References Caron, J.C., et al.: J. Pharmaceut. Sci., 73, 1703 (1984); Stouch, T.R., et al.: J. Med. Chem., 29, 2125 (1986);<br></p>Formula:C27H37FO6Color and Shape:WhiteMolecular weight:476.58Desonide-21-aldehyde Hydrate
Controlled ProductFormula:C24H32O7Color and Shape:White To Light YellowMolecular weight:432.507Eplerenone Hydroxyacid Potassium Salt
CAS:Controlled Product<p>Applications A metabolite of Eplerenone. Used in combination therapy for treatment of cardiovascular disorders.<br>References Staessen, J., et al.: J. Endocrinol., 91, 457 (1981), de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), MacFadyen, R., et al.: Cardiovasc. Res., 35, 30 (1997),<br></p>Formula:C24H31O7·KColor and Shape:Off-White To Light YellowMolecular weight:470.60Testosterone 17-Decanoate
CAS:Controlled Product<p>Applications Testosterone 17-Decanoate, is an ester of Testosterone (T155000). Testosterone 17-Decanoate, can be used as a potential long-acting male contraceptive, with the combination of subcutaneous etonogestrel implants .<br>References Brady, B. M., et al.: Human Reproduction, 21 (1), 285 (2006); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000);<br></p>Formula:C29H46O3Color and Shape:NeatMolecular weight:442.6717-Hydroxy Pregnenolone
CAS:Controlled Product<p>Applications 17-Hydroxy Pregnenolone, is a metabolite of Pregnenolone (P712200).<br>References Kramer, R., et al.: J. Steroid Biochemi., 18, 715 (1983), Hiwatashi, A., et al.: J. Biochem., 98, 619 (1985), Eiichi, T., et al.: J. Pharmacol. Sci., 95, 140 (2004),<br></p>Formula:C21H32O3Color and Shape:White To Off-WhiteMolecular weight:332.48(E)-Betamethasone-∆17,20 21-Aldehyde
CAS:Formula:C22H27FO4Color and Shape:NeatMolecular weight:374.4517β-Estradiol
CAS:Controlled Product<p>Impurity Ethinylestradiol EP Impurity D<br>Applications 17b-Estradiol is the major estrogen (1) secreted by the premenopausal ovary (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.<br></p>Formula:C18H24O2Color and Shape:NeatMolecular weight:272.38Testosterone 17-Isobutyrate
CAS:Controlled Product<p>Applications Testosterone ester.<br>References Zarzycki, P., et al.: Anal. Bioanal. Chem., 391, 2219 (2008), Talarovicova, A., et al.: Hormon. Behav., 55, 235 (2009),<br></p>Formula:C23H34O3Color and Shape:Off-WhiteMolecular weight:358.51Flurandrenolide
CAS:Controlled Product<p>Applications Glucocorticoid; antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Formula:C24H33FO6Color and Shape:NeatMolecular weight:436.5117β-Hydroxyprogesterone
CAS:Controlled ProductFormula:C21H30O3Color and Shape:NeatMolecular weight:330.46Hydroxy Flutamide-d6
CAS:Controlled ProductFormula:C11H5D6F3N2O4Color and Shape:Light Yellow SolidMolecular weight:298.254-Hydroxy Atorvastatin-d5 Hemicalcium Salt
CAS:Controlled Product<p>Applications di(4-Hydroxy Atorvastatin-d5) Calcium Salt is a labeled metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Formula:C66H58D10CaF2N4O12Color and Shape:Beige SolidMolecular weight:1197.4Tachysterol3 (80%)
CAS:Controlled Product<p>Impurity Cholecalciferol EP Impurity E<br>Stability Light Sensitive, Temperature Sensitive, Unstable in DMSO<br>Applications Tachysterol3 (Cholecalciferol EP Impurity E) is a bioactive, synthetic vitamin D3 analog.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bouillon, R., et al.: Endocr. Rev., 16, 200 (1995), Ettinger, R., et al.: Adv. Drug Res., 28, 269 (1996), Doi, T., et al.: Tetrahedr. Lett., 45, 5727 (2004),<br></p>Formula:C27H44OPurity:80%Color and Shape:Colourless To YellowMolecular weight:384.64
