Organic Phosphates and Phosphonates
Organic phosphates are compounds that contain a phosphate group (-PO₄) attached to a carbon atom within an organic structure, typically in combination with alcohols, acids, or amines. These compounds are used in API formulation to enhance the solubility, stability, and bioavailability of active ingredients. Organic phosphates also play a role in controlled drug release and in improving the absorption of certain medications.
Organic phosphonates contain a phosphonate group (-PO₃H₂) in which the phosphorus atom is bonded to a carbon atom and two oxygen groups. These compounds have important pharmacological properties, particularly in enzyme inhibition and biochemical process modulation. Organic phosphonates are used in the production of APIs that target bone metabolism, bacterial infections, or antiviral treatments due to their specific biological effects.
At CymitQuimica, we offer organic phosphates and phosphonates for research in medicinal chemistry, biochemistry, and the development of advanced formulations.
Found 1201 products of "Organic Phosphates and Phosphonates"
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N-Dechloroethyl Cyclophosphamide
CAS:<p>Stability Reacts with DMSO<br>Applications A metabolite of Cyclophosphamide (C988580).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bohnenstengel, F., et al.: Eur. J. Clin. Pharmacol., 51, 297 (1996), Busse, D., et al.: J. Clin. Oncol., 15, 188 (1997), Roy, P., et al.: Drug Metab. Dispos., 27, 655 (1999),<br></p>Formula:C5H12ClN2O2PColor and Shape:NeatMolecular weight:198.59(R,S)-4-Hydroxy Cyclophosphamide-d4 Preparation Kit
CAS:Controlled ProductFormula:C7H11D4Cl2N2O3PColor and Shape:White To Off-WhiteMolecular weight:281.11(S)-(-)-3-Acetylthio-2-methylpropionic Acid
CAS:Controlled Product<p>Applications S-Acetylthio-2-methylpropionic Acid (S-AMPA) is a key chiral intermediate for Captopril (C175750) and other hypertension drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cushman, D., et al.: Biochem., 16, 5484 (1977), Ondetti, M., et al.: J. Med. Chem., 24, 355 (1981), Tseng, T., et al.: Cancer Lett., 62, 233 (1992),<br></p>Formula:C6H10O3SColor and Shape:ColourlessMolecular weight:162.214-Ethoxy-2-isopropyl-6-methylpyrimidine
CAS:Controlled Product<p>Applications 4-Ethoxy-2-isopropyl-6-methylpyrimidine, is the product of Diazinon (D416880) decomposition, an organophosphorus pesticide.<br>References Mekhakyan, L. A., et al.: Nov. Khim. Sredstva Zashch. , 62 (1979); Sovocool, G. W., et al.: J. Anal. Toxic., 5, 73 (1981);<br></p>Formula:C10H16N2OColor and Shape:NeatMolecular weight:180.25Bis(2-chloroethyl)-1,1,2,2-d4-amine Hydrochloride
CAS:Controlled Product<p>Applications Isotope labelled Bis(2-chloroethyl)amine is a cytotoxic metabolite of Cyclophosphamide; a deuterated analog of Nor-nitrogen mustard.<br>References Colvin, M., et al.: Cancer Res., 36, 1121 (1976), Ludeman, S., et al.: Drug Metab Dispos., 20, 337 (1992), Ludeman, S.M., et al.: J. Pharmaceut. Sci., 84, 393 (1995), Yu, L., et al.: Drug Metab. Dispos., 24, 1254 (1996),<br></p>Formula:C42H4H5Cl2N·ClHColor and Shape:NeatMolecular weight:182.51Epicaptopril
CAS:<p>Stability Air Sensitive<br>Applications Epicaptopril is an impurity of Captopril (C175750) which is an orally active angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978);<br></p>Formula:C9H15NO3SColor and Shape:White To Off-WhiteMolecular weight:217.28Glufosinate-d3 Hydrochloride
CAS:Controlled Product<p>Stability Very Hygroscopic<br>Applications Labelled Glufosinate (G596952). Used as a herbicide.<br>References Abbas, H., et al.: J. Agric. Food Chem., 50, 5246<br></p>Formula:C52H3H9NO4P·ClHColor and Shape:White To Light BeigeMolecular weight:220.61Captopril
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Orally active angiotensin-converting enzyme (ACE) inhibitor. Neuroprotective & Neuroresearch Product.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978),<br></p>Formula:C9H15NO3SColor and Shape:NeatMolecular weight:217.29Miltefosine
CAS:Controlled Product<p>Applications A phospholipid drug with antineoplastic and antiprotozoal/antifungal properties, also acts as an Akt inhibitor, and under investigation as a potential therapy against HIV infection.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chugh, P., et al al.: Retrovirology, 5, 11 (2008), Dorio, T., et al.: Antimicrob. Agents Chemother., 52, 2855 (2008),<br></p>Formula:C21H46NO4PColor and Shape:NeatMolecular weight:407.57Zoledronic Acid-15N2,13C2
CAS:Controlled ProductFormula:C313C2H1015N2O7P2Color and Shape:NeatMolecular weight:276.06Ethylenediamine-N,N,N’,N’-tetraacetic Acid-13C4
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Ethylenediaminetetraacetic Acid (E917745). EDTA is a powerful chelating agent; EDTA forms stable complexes with most metal ions. EDTA is used in treatment of lead and heavy metal poisoning of farm animals.<br>References Heindorff, K., et al.: Mutat. Res., 115, 149 (1983), Grier, M.T., et al.: Ann. Pharmacother., 27, 1504 (1993), Krokidis, A.A., et al.: Anal. Chim. Acta, 535, 57 (2005),<br></p>Formula:C4C6H16N2O8Color and Shape:NeatMolecular weight:296.2133N-Nitroso Delapril
CAS:Controlled ProductFormula:C26H31N3O6Color and Shape:Light YellowMolecular weight:481.541N,N-Bis(2-chloroethyl)phosphorodiamidic Acid Cyclohexylamine Salt
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications N,N-Bis(2-chloroethyl)phosphorodiamidic Acid Cyclohexylamine Salt is a cytotoxic metabolite of Cyclophosphamide (C988580).<br>References Driven, H.A.A.M. et al.: Chem. BIol. Inter., 93, 185 (1994); Fenselau, C. et al.: Xenobiotica, 22, 1207 (1992);<br></p>Formula:C10H24Cl2N3O2PColor and Shape:NeatMolecular weight:320.2Cilazaprilat
CAS:Controlled Product<p>Applications The active metabolite of Cilazapril. An ACE inhibitor. Antihypertensive.<br>References Natoff, I.L., et al.: J. Cardiovasc. Pharmacol., 7, 569 (1985), Szucs, T., et al.: Drugs, 41, Suppl.1, 18 (1991), Pordy, R.C., et al.: Cardiology, 86, 41 (1995),<br></p>Formula:C20H27N3O5Color and Shape:Off-WhiteMolecular weight:389.455-Descyano Milrinone 5-Carboxyamide
CAS:<p>Impurity Milrinone USP Related Compound A<br>Stability Hygroscopic<br>Applications 5-Descyano Milrinone 5-Carboxyamide (Milrinone USP Related Compound A) is an impurity of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Cardiotonic.<br>References Alousi, A.A., et al.: J. Cardiovasc Pharmacol., 5, 792 (1983), Maskin, C.S., et al.: Circulation, 67, 1065 (1983), Sinoway, L.S., et al.: J. Am. Coll. Cardiol., 2, 327 (1983), Baim, D.S., et al.: N. Engl. J. Med., 309, 748 (1983),<br></p>Formula:C12H11N3O2Color and Shape:Light YellowMolecular weight:229.23N-Nitroso Cilazapril (Ethyl-D5)
CAS:Controlled ProductFormula:C22D5H25N4O6Color and Shape:NeatMolecular weight:451.528Captopril-d3
CAS:Controlled Product<p>Applications Orally active angiotensin-converting enzyme (ACE) inhibitor.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978),<br></p>Formula:C9D3H12NO3SColor and Shape:White SolidMolecular weight:220.30Tris(1,3-dichloro-2-propyl) Phosphate-d15
CAS:Controlled Product<p>Applications Isotope labelled Tris(1,3-dichloro-2-propyl) Phosphate is a flame retardant present in polyurethane foams.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stapleton, H. et al.: Env. Sci. Tech., 45, 5323 (2011);<br></p>Formula:C9D15Cl6O4PColor and Shape:Colourless To BrownMolecular weight:446.00N-Nitroso Bis(2-chloroethyl)amine
CAS:<p>Applications N-Nitroso bis(2-chloroethyl)amine is a nitroamine compound that has carcinogenic effects.<br>References Luan, F. et al.: Che. Res. in Tox., 18(2), 198-203, (2005)<br></p>Formula:C4H8Cl2N2OColor and Shape:NeatMolecular weight:171.025
