Organic Phosphates and Phosphonates
Organic phosphates are compounds that contain a phosphate group (-PO₄) attached to a carbon atom within an organic structure, typically in combination with alcohols, acids, or amines. These compounds are used in API formulation to enhance the solubility, stability, and bioavailability of active ingredients. Organic phosphates also play a role in controlled drug release and in improving the absorption of certain medications.
Organic phosphonates contain a phosphonate group (-PO₃H₂) in which the phosphorus atom is bonded to a carbon atom and two oxygen groups. These compounds have important pharmacological properties, particularly in enzyme inhibition and biochemical process modulation. Organic phosphonates are used in the production of APIs that target bone metabolism, bacterial infections, or antiviral treatments due to their specific biological effects.
At CymitQuimica, we offer organic phosphates and phosphonates for research in medicinal chemistry, biochemistry, and the development of advanced formulations.
Found 1191 products of "Organic Phosphates and Phosphonates"
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Cilazaprilat
CAS:Controlled Product<p>Applications The active metabolite of Cilazapril. An ACE inhibitor. Antihypertensive.<br>References Natoff, I.L., et al.: J. Cardiovasc. Pharmacol., 7, 569 (1985), Szucs, T., et al.: Drugs, 41, Suppl.1, 18 (1991), Pordy, R.C., et al.: Cardiology, 86, 41 (1995),<br></p>Formula:C20H27N3O5Color and Shape:Off-WhiteMolecular weight:389.455-Descyano Milrinone 5-Carboxyamide
CAS:<p>Impurity Milrinone USP Related Compound A<br>Stability Hygroscopic<br>Applications 5-Descyano Milrinone 5-Carboxyamide (Milrinone USP Related Compound A) is an impurity of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Cardiotonic.<br>References Alousi, A.A., et al.: J. Cardiovasc Pharmacol., 5, 792 (1983), Maskin, C.S., et al.: Circulation, 67, 1065 (1983), Sinoway, L.S., et al.: J. Am. Coll. Cardiol., 2, 327 (1983), Baim, D.S., et al.: N. Engl. J. Med., 309, 748 (1983),<br></p>Formula:C12H11N3O2Color and Shape:Light YellowMolecular weight:229.23N-Nitroso Cilazapril (Ethyl-D5)
CAS:Controlled ProductFormula:C22D5H25N4O6Color and Shape:NeatMolecular weight:451.528Captopril-d3
CAS:Controlled Product<p>Applications Orally active angiotensin-converting enzyme (ACE) inhibitor.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978),<br></p>Formula:C9D3H12NO3SColor and Shape:White SolidMolecular weight:220.30Tris(1,3-dichloro-2-propyl) Phosphate-d15
CAS:Controlled Product<p>Applications Isotope labelled Tris(1,3-dichloro-2-propyl) Phosphate is a flame retardant present in polyurethane foams.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stapleton, H. et al.: Env. Sci. Tech., 45, 5323 (2011);<br></p>Formula:C9D15Cl6O4PColor and Shape:Colourless To BrownMolecular weight:446.00N-Nitroso Bis(2-chloroethyl)amine
CAS:<p>Applications N-Nitroso bis(2-chloroethyl)amine is a nitroamine compound that has carcinogenic effects.<br>References Luan, F. et al.: Che. Res. in Tox., 18(2), 198-203, (2005)<br></p>Formula:C4H8Cl2N2OColor and Shape:NeatMolecular weight:171.025Malathion-d6
CAS:Controlled Product<p>Applications Used as an insecticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C102H6H13O6PS2Color and Shape:NeatMolecular weight:336.40N-Nitroso Cilazapril
CAS:Controlled ProductFormula:C22H30N4O6Color and Shape:NeatMolecular weight:446.5Captopril Disulfide
CAS:<p>Impurity Captopril EP Impurity A<br>Applications Captopril Disulfide (Captopril EP Impurity A) is a metabolite of Captopril. A new antihypertensive agent.<br>References Sprague, P., et al.: Perspect. Drug Discovery Des., 3, 21 (1995), Cushman, D., et al.: Nat. Med., 5, 1110 (1999), Jacoby, E., et al.: Drug News Perspect., 16, 93 (2003), Lengauer, T., et al.: Drug Discovery Today, 9, 27 (2004),<br></p>Formula:C18H28N2O6S2Color and Shape:WhiteMolecular weight:432.55Nitrilotris(methylene)triphosphonic Acid
CAS:Controlled Product<p>Applications A powerful complexing agent. A potent acid sphingomyelinase inhibitor.<br>References Marathe, S., et al.: J. Biol. Chem., 273, 4081 (1998), Lang, P., et al.: Nat. Med., 13, 164 (2007), Nara, F., et al.: J. Antibiot., 52, 525 (1999), Szajnman, S., et al.: Bioorg. Med. Chem. Lett., 15, 4685 (2005),<br></p>Formula:C3H12NO9P3Color and Shape:NeatMolecular weight:299.053-[[2-[(2-Chloroethyl)amino]ethyl]amino]propyl Monophosphate Dihydrochloride
CAS:Controlled Product<p>Impurity Cyclophosphamide Impurity D Dihydrochloride<br>Stability Hygroscopic<br>Applications A metabolite of Cyclophosphamide (C988580).<br>References Joqueviel, C. et al.: Drug Metab. Dispos., 26, 418 (1998);<br></p>Formula:C7H18ClN2O4P·2ClHColor and Shape:White To Off-WhiteMolecular weight:333.584-Oxo Cyclophosphamide
CAS:<p>Applications A minor metabolite of Cyclophosphamide<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Juma, F., et al.: Br. J. Clin. Pharmacol., 10, 327 (1980), Powers, J., et al.: Cancer Res., 43, 1101 (1983), Hardy, R., et al.: Ther. Drug Monit., 9, 221 (1987),<br></p>Formula:C7H12Cl2NO4PColor and Shape:NeatMolecular weight:276.05Deferasirox Ferrate(III) Tripotassium Complex Methanoate Hydrate
CAS:<p>Applications A metal complex of Deferasirox (D228650) as oxidation catalysts. Coordination compound.<br>References Rouan, M., et al.: Biomed. Sci. Applic., 755, 203 (2001)<br></p>Formula:C44H36FeK3N6O12Color and Shape:NeatMolecular weight:1013.93Diethyl (Ethoxycarbonyl)phosphonate
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications Diethyl (Ethoxycarbonyl)phosphonate is an impurity in the synthesis of Foscarnet (F727400), an inhibitor of viral DNA polymerase and reverse transcriptase. Foscarnet is used as an antiviral.<br>References Helgstrand, E., et al.: Science, 201, 819 (1978), Reno, J.M., et al.: Antimicrob. Agents Chemother., 13, 188, (1978), Alenius, S., et al.: Arch. Virol., 60, 197 (1979),<br></p>Formula:C7H15O5PColor and Shape:NeatMolecular weight:210.16Zoledronic-d3 Acid
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Zoledronic-d3 Acid is the labeled analogue of Zoledronic Acid (Z623500), a biphosphonate bone resorption inhibitor.<br>References Green, J.R., et al.: J. Bone Min. Res., 9, 745 (1994); Risser, F., et al.: J. Pharm. Biomed. Anal., 15, 1877 (1997); Body, J.J., Cancer, 80, 1699 (1997)<br></p>Formula:C5H7D3N2O7P2Color and Shape:NeatMolecular weight:275.112-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one
CAS:Controlled Product<p>Applications Intermediate in the production of Deferasirox.<br></p>Formula:C14H9NO3Color and Shape:NeatMolecular weight:239.23Diazinon-d10
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A labelled cholinesterase inhibitor; a nonsystemic organophosphate insecticide. Used as a standard for Pesticide detection.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gaines, T.B., et al.: Toxicol. Appl. Pharmacol., 14, 515 (1969),<br></p>Formula:C122H10H11N2O3PSColor and Shape:ColourlessMolecular weight:314.41(6-Amino-1-hydroxyhexane-1,1-diyl)diphosphonic acid
CAS:Purity:95.0%Molecular weight:277.1499938964844Malathion
CAS:<p>Applications Malathion is a pestanal and used primarily as an insecticide. Malathion is also useful in cannabis testing kits as a component of pesticide mixes (P698230).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Josse, R et al.: Chem. Bio., Interact., 209, 76 (2014);<br></p>Formula:C10H19O6PS2Color and Shape:Colourless To Light YellowMolecular weight:330.362-Isopropyl-6-methyl-4-pyrimidone
CAS:Controlled Product<p>Applications 2-Isopropyl-6-methyl-4-pyrimidone, is an intermediate used for the synthesis of various benzophenone derivatives, having antifungal and antibacterial activities. It can also be used for the synthesis of Diazinon (D416880), and Diazoxon (D416890), the organophosphate insecticides.<br>References Sun, L., et al.: Molecules, 16, 9739 (2011); Pasti, T. L., J. Environ. Protect. Ecology, 12, 1168 (2011);<br></p>Formula:C8H12N2OColor and Shape:NeatMolecular weight:152.19Fenthion-d6
CAS:Controlled Product<p>Applications Labelled Fenthion, an organothiophosphate insecticide. Fenthion is also a potent acaricide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pati, B.R. et al.: Plant Soil, 80, 215 (1984); Barros, A.T. et al.: Vet. Parasitol., 96, 243 (2001); Kyriakidis, N.V. et al.: Food Chem., 91, 241 (2005);<br></p>Formula:C102H6H9O3PS2Color and Shape:ColourlessMolecular weight:284.36Terbufos-sulfoxide
CAS:Controlled Product<p>Applications Terbufos-sulfoxide was identified in vegetables and fruit by gas chromotography.<br>References Zhang, Q., et al.: Shandong Huagong, 45, 57 (2016)<br></p>Formula:C9H21O3PS3Color and Shape:NeatMolecular weight:304.433-Acetylthio-2-methylpropionic Acid
CAS:Controlled Product<p>Impurity Captopril EP Impurity G<br>Applications 3-Acetylthio-2-methylpropionic Acid (Captopril EP Impurity G) is a key intermediate for Captopril (C175750) and other hypertension drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cushman, D., et al.: Biochem., 16, 5484 (1977), Ondetti, M., et al.: J. Med. Chem., 24, 355 (1981), Tseng, T., et al.: Cancer Lett., 62, 233 (1992),<br></p>Formula:C6H10O3SColor and Shape:NeatMolecular weight:162.214-Hydroperoxy Cyclophosphamide-d4
CAS:Controlled Product<p>Stability Moisture Sensitive, Temperature Sensitive<br>Applications A labelled metabolite of Cyclophosphamide. Antineoplastic; bone marrow purging agent.<br>References Takamizawa, A., et al.: J. Med. Chem., 18, 376 (1975), Jones, R.J., et al.: J. Hematother., 1, 343 (1992), Biggs, D., et al.: Prog. Clin. Biol. Res., 389, 9 (1994),<br></p>Formula:C7H11D4Cl2N2O4PColor and Shape:NeatMolecular weight:297.111,2-Dioleoyl-3-trimethylammonium-propane, Chloride
CAS:Controlled ProductFormula:C42H80NO4·ClColor and Shape:NeatMolecular weight:698.54Toldimfos Sodium
CAS:Controlled Product<p>Applications Toldimfos Sodium, is a cattle drug that can be used to investigate the bovine serum paraoxonase 1 (PON1) activity.<br>References Arslan, M., et al.: J. Enzyme Inhibit. Med. Chem., 27, 722 (2012);<br></p>Formula:C9H13NO2P·NaColor and Shape:White To Off-WhiteMolecular weight:221.173-Mercapto-2-methylpropanoic Acid
CAS:Controlled Product<p>Impurity Captopril EP Impurity C<br>Applications 3-Mercapto-2-methylpropanoic Acid (Captopril EP Impurity C) is a useful synthetic intermediate.<br>References Lewis, S.N. et al.: J. Het. Chem., 8, 571-580 (1971)<br></p>Formula:C4H8O2SColor and Shape:NeatMolecular weight:120.17Cilazapril
CAS:Controlled Product<p>Applications An ACE inhibitor. Hydrolyzed in vivo to the active diacid metabolite (Cilazaprilat). Antihypertensive.<br>References Natoff, I.L., et al.: J. Cardiovasc. Pharmacol., 7, 569 (1985), Szucs, T., et al.: Drugs, 41, Suppl.1, 18 (1991), Pordy, R.C., et al.: Cardiology, 86, 41 (1995),<br></p>Formula:C22H31N3O5Color and Shape:WhiteMolecular weight:417.50Phosphoric Acid Potassium
CAS:<p>Stability Hygroscopic<br>Applications Potassium salt of Phosphoric Acid (P359200), used in various chemical processes as a phosphorylating compound. Also used in the preparation of prosthetics and collagen nanocomposites due to the bone-like properties. pH buffer.<br>References Ezhova, Z. et al.: Russ. J. Inorg. Chem., 58, 1177 (2013); Wu, Y. et al.: Asian J. Chem., 25, 5881 (2013);<br></p>Formula:K·H2O4PColor and Shape:WhiteMolecular weight:136.09Carboxyphosphamide
CAS:Controlled Product<p>Applications A metabolite of Cyclophosphamide (CPA) (C988580).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Takamizawa, A., et al.: J. Med. Chem., 18, 376 (1975), Jones, R.J., et al.: J. Hematother., 1, 343 (1992), Biggs, D., et al.: Prog. Clin. Biol. Res., 389, 9 (1994),<br></p>Formula:C7H15Cl2N2O4PColor and Shape:NeatMolecular weight:293.08Fenthion
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications Fenthion is an organothiophosphate used as an insecticide. Fenthion is also a potent acaricide. Useful in cannabis testing kits as a component of pesticide mixes (P698230).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pati, B.R. et al.: Plant Soil, 80, 215 (1984); Barros, A.T. et al.: Vet. Parasitol., 96, 243 (2001); Kyriakidis, N.V. et al.: Food Chem., 91, 241 (2005);<br></p>Formula:C10H15O3PS2Color and Shape:Colourless To Light YellowMolecular weight:278.33Malathion β-Monoacid
CAS:<p>Stability Hygroscopic<br>Applications A major biodegradation product of Malathion (M111000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, Y. et al.: Chemosphere, 60, 1349 (2005); Yoshii, K. et al.: J. Health Sci., 54, 535 (2008); Hayasaka, M. et al.: Jap. J. Forensic Toxicol., 12, 15 (1994);<br></p>Formula:C8H15O6PS2Color and Shape:NeatMolecular weight:302.30Difluoromethylenediphosphonic Acid
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A phosphonic acid derivative for development of biologically active compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ma, Q.F., et al.: Biochemistry, 29, 1412 (1990), Soti, C., et al.: Eur. J. Biochem., 270, 2421 (2003), Barabas, O., et al.: J. Biol. Chem., 279, 42907 (2004),<br></p>Formula:CH4F2O6P2Color and Shape:NeatMolecular weight:211.98Amifostine Trihydrate
CAS:Controlled Product<p>Applications Amifostine Trihydrate is a widely used cytoprotective and radio-protective agent.<br>References Adibhatla K.S., et al. Novel method of manufacture of high purity Amifostine trihydrate. Indian Pat. Appl. IN 2005CH01592 A 20080125. Jan 25, 2008<br></p>Formula:C5H15N2O3PS·3H2OColor and Shape:NeatMolecular weight:268.27Alendronic Acid-d6 Sodium Salt Hydrate
CAS:Controlled Product<p>Applications Alendronic Acid-d6 Sodium Salt is a labelled salt analogue of Alendronic Acid (A521250), a bisphosphonate used as a bone reabsoption inhibitor.<br>References Wang, X.M., et al.: Clin. J. Dent. Res., 3, 26 (2000); Woo, T., et al.: Best Pract. Res. Clin. Rheumatol., 15, 469 (2001); Benford, H.L., et al.: Bone, 28, 465 (2001)<br></p>Formula:C4H6D6NNaO7P2xH2OColor and Shape:NeatMolecular weight:277.11Zofenopril Calcium Salt
CAS:<p>Applications Angiotensin-converting enzyme ACE inhibitor. A prodrug that is de-esterified to the active inhibitor, the sulfhydryl group containing metabolite, Zofenoprilat.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gorren, A., et al.: Biochem. J., 331, 801 (1998), Subissi, A., et al.: Cardivascular Drug Reviews, 17, 2 (1999), Marchand, C., et al.: Mol. Pharmacol., 64, 600 (2003), Maurin, C., et al.: J. Med. Chem., 47, 5583 (2004),<br></p>Formula:C22H22NO4S2·CaColor and Shape:NeatMolecular weight:897.17Triethyl Phosphonoacetate
CAS:Controlled Product<p>Applications Reagent used for Horner-Emmons modification.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hediger, M., et al.: Bioorg. Med. Chem., 12, 4995 (2004), Kim, J., et al.: Nat., 452, 239 (2008),<br></p>Formula:C8H17O5PColor and Shape:ColourlessMolecular weight:224.19Butafosfan
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Butafosfan, a component of Catosal, is licensed for the treatment of metabolic disorders or as a tonic in swine. It reduces the stress-induced cortisol (C696302, d4 labelled) response after mixing of unfamiliar pigs. It can also increase milk production in Holstein cows in combination with cyanocobalamin.<br>References De Groot, J., et al.: J. Vet. Pharmacol. Ther., 26, 222 (2003); Pereira, R., et al.: Animal, 7, 1143 (2013)<br></p>Formula:C7H18NO2PColor and Shape:White To Off-WhiteMolecular weight:179.20(4S)-4-(Phenylthio)-L-proline Hydrochloride
CAS:<p>Applications (4S)-4-(Phenylthio)-L-proline is an impurity of Zofenopril (Z587000).<br>References Krapcho, J., et al.: J. Med. Chem., 31, 1148 (1988),<br></p>Formula:C11H14ClNO2SColor and Shape:NeatMolecular weight:259.753-Aminopropyl Monophosphate
CAS:Controlled Product<p>Applications A metabolite of the anti-tumor drug Ifosfamide (I265000). An impurity of Cyclophosphamide (C988580).<br>References Gilard, V. et al.: J. Med. Chem., 42, 2542 (1999); Seligman, A.M. et al.: Cancer Chemother. Rep., 59, 233 (1975);<br></p>Formula:C3H10NO4PColor and Shape:White To Off-WhiteMolecular weight:155.09Malathion Diacid Dipotassium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A biodegradation product of Malathion (M111000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, Y. et al.: Chemosphere, 60, 1349 (2005); Yoshii, K. et al.: J. Health Sci., 54, 535 (2008); Hayasaka, M. et al.: Jap. J. Forensic Toxicol., 12, 15 (1994);<br></p>Formula:C6H9K2O6PS2Color and Shape:NeatMolecular weight:350.43(2-(3,6-Dimethoxy-9H-carbazol-9-yl)ethyl)phosphonic acid
CAS:Purity:98%Molecular weight:335.2959899902344Dichlorvos-d6
CAS:Controlled Product<p>Applications Dichlorvos-d6 is a deuterated analogue of Dichlorvos a Cholinesterase inhibitor. Anthelmintic, insecticide. Used as a standard for Pesticide detection. Also used in Cannabis testing.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gaines, T.B., et al.: Toxicol. Appl. Pharmacol., 14, 515 (1969), Reuber, M.D., et al.: Clin. Toxicol., 18, 47 (1981),<br></p>Formula:C42H6HCl2O4PColor and Shape:Clear Colourless To BrownMolecular weight:227.01Ethylenediamine-N,N,N’,N’-tetraacetic Acid-13C4
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Ethylenediaminetetraacetic Acid (E917745). EDTA is a powerful chelating agent; EDTA forms stable complexes with most metal ions. EDTA is used in treatment of lead and heavy metal poisoning of farm animals.<br>References Heindorff, K., et al.: Mutat. Res., 115, 149 (1983), Grier, M.T., et al.: Ann. Pharmacother., 27, 1504 (1993), Krokidis, A.A., et al.: Anal. Chim. Acta, 535, 57 (2005),<br></p>Formula:C4C6H16N2O8Color and Shape:NeatMolecular weight:296.2133D-Captopril
CAS:Controlled Product<p>Applications D-Captopril and Captopril analogues are New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors which are used clinically as antidotes for metal poisoning and bacterial infection.<br>References Ningning; X., et al.: Bioorg. Med. Chem. Lett., 24, 386 (2014); Guo, Y., et al.: Protein Cell, 2, 384 (2011)<br></p>Formula:C9H15NO3SColor and Shape:NeatMolecular weight:217.285Fenthion Sulfoxide
CAS:Controlled Product<p>Applications Fenthion Sulfoxide is the sulfoxide anlogue and metabolite of the organothiophosphate insecticide Fenthion (F278000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wallnoefer, P. et al.: Pflanzensch.-Nach., 29, 236 (1976); Minelli, E.V. et al.: J. Agric. Food. Chem., 44, 936 (1996);<br></p>Formula:C10H15O4PS2Color and Shape:NeatMolecular weight:294.33
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