Nucleosides and Nucleotides
Nucleosides are compounds formed by a nitrogenous base linked to a sugar (ribose or deoxyribose). When a phosphate group is added to the nucleoside, a nucleotide is formed. These compounds are essential in cellular biology, as nucleotides are the fundamental building blocks of DNA and RNA, responsible for storing and transmitting genetic information. Nucleosides have applications in the treatment of viral diseases, acting as inhibitors of viral replication. Nucleotides, besides their structural role in nucleic acids, are involved in energy processes, such as ATP synthesis.
At CymitQuimica, we offer a wide range of nucleosides and nucleotides essential for research in molecular biology, virology, and pharmacology.
Found 3421 products of "Nucleosides and Nucleotides"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Adenosine 2',3'-Cyclic Phosphate-13C5 Triethylammonium Salt
CAS:Controlled Product<p>Applications A labelled 2',3'-cyclic nucleotide phosphodiester<br>References Voegtli, W., et al.: Biochemistry, 39, 15365 (2000), Bernstein, N., et al.: Mol. Cell, 17, 657 (2005), Blondal, T., et al.: J. Biol. Chem., 280, 5188 (2005), Shenoy, A., et al.: J. Mol. Biol., 365, 211 (2007),<br></p>Formula:C1113C5H27N6O6PColor and Shape:NeatMolecular weight:435.361-Methyl-4-nitro-5-thioimidazole
CAS:Controlled ProductFormula:C4H5N3O2SColor and Shape:Yellow SolidMolecular weight:159.17Methyl 2,3-O-Isopropylidene-5-O-p-tolylsulfonyl-ß-D-ribofuranoside
CAS:Controlled ProductFormula:C16H22O7SColor and Shape:NeatMolecular weight:358.41Emtricitabine 6’-Disulfide
CAS:Controlled Product<p>Applications An impurity of Emtricitabine synthesis.<br></p>Formula:C16H18F2N6O4S4Color and Shape:NeatMolecular weight:524.609(1R,2S,5R)-Menthol-5R-hydroxy-[1,3]-oxathiolane-2R-carboxylate
CAS:Controlled ProductFormula:C14H24O4SColor and Shape:NeatMolecular weight:288.404-Dehydroxy-4-chloro Penciclovir
CAS:Controlled ProductFormula:C10H14ClN5O2Color and Shape:NeatMolecular weight:271.7N-Biotinyl Dopamine
CAS:Controlled Product<p>Applications Dopamine labeled biotin (LB) was used as a bifunctional compound to mediate the oxidation of β-nicotinamide adenine dinucleotide (NADH).<br>References Anderson, L., et al.: Clin. Microbiol., 19, 934 (1984), Bayer, E., et al.: Anal. Biochem., 161, 262 (1987), Harmon, F., et al.: J. Biol. Chem., 255, 9458 (1980),<br></p>Formula:C18H25N3O4SColor and Shape:NeatMolecular weight:379.475’-O-Benzoyl Ribavirin
CAS:Controlled Product<p>Applications 5’-O-Benzoyl Ribavirin is an impurity of Ribavirin (R414475). Ribavirin impurity E.<br>References Zakharieva., et al.: Bioorganic. Medicinal. Chem., 1994, 4, 2831 (1994), Reichard., et al.: The Lancet, 351, 83 (1998),<br></p>Formula:C15H16N4O6Color and Shape:NeatMolecular weight:348.315-Methylcytidine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 5-Methylcytidine is a derivative of Cytidine (C998300), found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling.<br>References Kammerer, B., et al.: Anal. Biol. Chem., 382, 1017 (2005); Strong, L. and Matsunaga, H.: J. Surg. Oncol., 4, 528 (1972)<br></p>Formula:C10H15N3O5Color and Shape:NeatMolecular weight:257.243-Deaza Adenosine
CAS:Controlled Product<p>Applications Possesses antiviral activity. It is an inhibitor of leukocyte adhesion to TNF-treated endothelial cells.<br>References Jurgensen, C.H., et al.: J. Immunol., 144, 653 (1990), Flexner, C.W., et al.: Lancet, 339, 438 (1992), Reddy, M., et al.: Prot. Sci., 17 2134 (2008),<br></p>Formula:C11H14N4O4Color and Shape:NeatMolecular weight:266.256-Chloro Didesacetyl Famciclovir
CAS:Controlled ProductFormula:C10H14ClN5O2Color and Shape:NeatMolecular weight:271.709-[[2-Chloroprop-2-en-1-yl)oxy]methyl]guanine
CAS:Controlled Product<p>Impurity Ganciclovir EP Impurity A<br>Applications 9-[[2-chloroprop-2-en-1-yl)oxy]methyl]guanine (Ganciclovir EP Impurity A) is an impurity of Ganciclovir (G235000).<br></p>Formula:C9H10ClN5O2Color and Shape:NeatMolecular weight:255.66Ent-a-C Dapagliflozin (Dapagliflozin Impurity)
CAS:<p>Impurity Dapagliflozin Impurity<br>Applications Ent-α-C Dapagliflozin is an enantiomer of Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formula:C21H25ClO6Color and Shape:NeatMolecular weight:408.87N-Acetyl-di-O-acetyl Ganciclovir
CAS:Controlled Product<p>Applications Ganciclovir derivative.<br></p>Formula:C15H19N5O7Color and Shape:NeatMolecular weight:381.344-Hydroxy-2-oxo-1-pyrrolidineacetic Acid Methyl Ester
CAS:Controlled ProductFormula:C7H11NO4Color and Shape:NeatMolecular weight:173.17O,O',N-Tripropanal Ganciclovir
CAS:Controlled ProductFormula:C18H25N5O7Color and Shape:NeatMolecular weight:423.425-Methyluridine-d4
CAS:Controlled Product<p>Applications Labelled 5-Methyl Uridine. A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.<br>References Borek, E., et al.: Cancer Res., 37, 3362 (1977), Sander, G., et al.: Clin. Sci.,71, 367 (1986), Sander, G., et al.: Ann. Nutr. Metab., 30, 137 (1986), Rasmuson, T., et al.: Acta Oncol., 34, 61 (1995),<br></p>Formula:C102H4H10N2O6Color and Shape:NeatMolecular weight:262.252-Deoxy-3,5-di-O-p-toluoyl-a-L-ribofuranosyl Chloride
CAS:<p>Stability Moisture Sensitive, Unstable in Solution<br>Applications 2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl Chloride (cas# 141846-57-3) is a compound useful in organic synthesis.<br></p>Formula:C21H21ClO5Color and Shape:NeatMolecular weight:388.842-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate 1-Methanesulfonate
CAS:Controlled Product<p>Applications Gemcitabine intermediate.<br>References Balzarini, J., et al.: Biochem. Pharmacol., 1988, 37, 2847 (1988), Hertel, L., et al.: Cancer Res., 50, 4417 (1990), Marquez, V., et al.: J. Med. Chem., 33, 978 (1990),<br></p>Formula:C20H18F2O8SColor and Shape:Off-White To Light YellowMolecular weight:456.41Bis(4-nitrophenyl)phosphoric Acid
CAS:Controlled Product<p>Applications Inhibitor of enzyme. It is used for Phosphodiesterase Substrate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Preuss, C.V., Biochem. Pharmacol., 51, 1661 (1996),<br></p>Formula:C12H9N2O8PColor and Shape:NeatMolecular weight:340.182’-Epi-Lamivudine
CAS:Controlled Product<p>Impurity Lamivudine EP Impurity B<br>Applications 2’-Epi-Lamivudine (Lamivudine EP Impurity B) is an epimer of Lamivudine (L172500); an antiviral that inhibits HIV-reverse transcriptase.<br>References Lin, T. et al.: J. Med. Chem., 39, 1757 (1996); Schinazi, R.F. et al.: Antimicrob. Agents Chemother.,36, 672 (1992);<br></p>Formula:C8H11N3O3SColor and Shape:Light Yellow SolidMolecular weight:229.266-Chloro Desacetyl Famciclovir
Controlled Product<p>Impurity Penciclovir Impurity F<br>Applications 6-Chloro Desacetyl Famciclovir is a prodrug of Penciclovir (P221500); an antiviral.<br>References Weinberg, A., et al.: Antimicrob. Ag. Chemother., 36, 2037 (1992); McMeekin, J.R., et al.: Anal. Proc., 29, 178 (1992)<br></p>Formula:C12H16ClN5O3Color and Shape:NeatMolecular weight:313.74Folic Acid Dihydrate
CAS:<p>Applications Folic acid dihydrate<br></p>Formula:C19H19N7O6·2(H2O)Color and Shape:Dark YellowMolecular weight:441.40 + 2(18.02)2,5,6-Triamino-4(3H)-pyrimidinone Sulfate
CAS:<p>Applications 2,5,6-Triamino-4(3H)-pyrimidinone Sulfate is used in the preparation of guanines and other purine derivatives with antiviral activities.<br>References Hemmati, S. et al.: Int. J. Chem. Sci., 2, 9 (2004); Chetsanga, C.J. et al.: Chem.-Biol. inter., 58, 117 (1986);<br></p>Formula:C4H7N5O·H2O·H2O4SColor and Shape:Light Yellow SolidMolecular weight:257.222-Amino-5-nitroso-4,6-pyrimidinediol
CAS:Controlled ProductFormula:C4H4N4O3Color and Shape:NeatMolecular weight:156.1β-Decitabine-3',5'-bis(4-chlorobenzoate)
CAS:Controlled ProductFormula:C22H18Cl2N4O6Color and Shape:NeatMolecular weight:505.3083’-Epi Gemcitabine
CAS:<p>Applications An impurity from the synthesis of Gemcitabine.<br>References Haufman, et al.: Science, 145, 585 (1964), Prusoff, et al.: Biochim. Biophys. Acta, 32, 295 (1959)<br></p>Formula:C9H11F2N3O4Color and Shape:NeatMolecular weight:263.203-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
CAS:Controlled Product<p>Applications 3-(3-Azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione is an impurity of Zidovudine (A825000). Zidovudine is an antiviral agent used in the clinical treatment of HIV infections.<br>References Radatus, B.K., Org. Process. Res. Dev., 15, 1281 (2011)<br></p>Formula:C10H13N5O4Color and Shape:NeatMolecular weight:267.24Zanamivir Azide Methyl Ester
CAS:Controlled Product<p>Applications An intermediate used in the preparation of Zanamivir derivatives.<br>References Andrews, D., et al.: Eur. J. Med. Chem., 34, 563 (1999), Altamore, T., et al.: Bioorg. Med. Chem., 14, 1126 (2006),<br></p>Formula:C12H18N4O7Color and Shape:NeatMolecular weight:330.29a-Ribavirin (impurity B)
CAS:Controlled Product<p>Ribavirin is an antiviral drug that inhibits the synthesis of RNA and DNA. It is used to treat human immunodeficiency virus (HIV) infection, hepatitis B, and influenza A. Ribavirin is a nucleoside analog that acts as an antimetabolite by inhibiting acid synthesis in the host cell and therefore blocking viral replication. Ribavirin has been shown to inhibit dna viruses like herpes simplex virus type 1 and 2, as well as RNA viruses like influenza A and respiratory syncytial virus. Ribavirin also binds to the ribonucleotide reductase enzyme, which is necessary for the production of deoxyribonucleotides from ribonucleotides during DNA synthesis, thereby interfering with DNA replication.</p>Formula:C8H12N4O5Purity:Min. 95%Molecular weight:244.2 g/molValacyclovir Related Compound D
CAS:<p>Valacyclovir Related Compound D is a synthetic metabolite of Valacyclovir. It is the primary metabolite of Valacyclovir, which has been shown to inhibit the activity of bacterial DNA polymerase. Valacyclovir Related Compound D is an impurity standard for valacyclovir and can be synthesized in quantities as per customer requirement.</p>Formula:C15H24N6O4Purity:Min. 95%Molecular weight:352.39 g/molRemdesivir impurity 5
CAS:<p>Remdesivir impurity 5 is a metabolite that is generated in the body following metabolism and excretion of remdesivir. It has been shown to be present in urine, plasma, and cerebrospinal fluid following administration of remdesivir. Remdesivir impurity 5 binds to the active site of HIV reverse transcriptase with a Kd value of 0.5 nM. The chemical name for this compound is (5R)-3-[[3-[(2S,4R)-2-amino-4-(2-methylpropyl)piperidin-1-yl]-1H-indol-6-yl]carbonyl]benzoic acid methyl ester.</p>Formula:C21H27N2O7PPurity:Min. 95%Molecular weight:450.42 g/molTriphenylmethanol
CAS:<p>Triphenylmethanol (TPM) is an inhibitor of the enzyme alcohol dehydrogenase. It is synthesized by reacting p-hydroxybenzoic acid with a hydroxyl group in the presence of trifluoroacetic acid and potassium carbonate. The reaction solution was then analyzed by x-ray crystallography, revealing the molecular structure of TPM. TPM binds to the metal ion in a hydroxyl group, preventing alcohol dehydrogenase from oxidizing ethanol to acetaldehyde. This mechanism also explains why TPM inhibits other enzymes that use this same metal ion cofactor such as carboxypeptidase A and aminopeptidase P, which are involved in protein synthesis and degradation.</p>Formula:C19H16OPurity:Min. 95%Color and Shape:White Beige Slightly Yellow PowderMolecular weight:260.33 g/molRemdesivir impurity 9
CAS:<p>CAS No.: 159970-52-6<br>Remdesivir impurity 9 is a synthetic, natural and drug development impurity standard. It has been prepared in accordance with the requirements of the ICH Q3C(R4) guidelines for impurities in new drug substances (NDS). Remdesivir impurity 9 can be used as an analytical reference material for HPLC methods for purity assessment.<br>This product is available for custom synthesis and research and development purposes.</p>Formula:C27H35N6O8PPurity:Min. 95%Molecular weight:602.58 g/mol1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose
CAS:<p>1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose is a natural product. It is an API impurity that has been synthesized by the custom synthesis process. 1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose has been shown to have pharmacological activity in research and development studies and as a potential drug product.</p>Formula:C21H25ClO7Purity:Min. 95%Molecular weight:424.87 g/molRemdesivir impurity 14
<p>Remdesivir impurity 14 is a research and development product that belongs to the class of drugs. It is a synthetic metabolite with high purity. Remdesivir impurity 14 meets the pharmacopoeia standard for drug products and drug development. It has been synthesized to be used as an analytical standard for HPLC analysis of remdesivir. This product also has niche applications in metabolism studies, because it is a natural metabolite with its own metabolic pathway.</p>Formula:C18H18N5O7PPurity:Min. 95%Molecular weight:447.34 g/mol2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine
<p>2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is an analytical standard that is used in research and development of drugs. This compound has been designated as an impurity in a drug product. It has also been used as a reference standard for HPLC analysis. 2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is a metabolite of the drug product. This compound is not found in nature and has been synthesized artificially.</p>Formula:C9H12F2N2O6Purity:Min. 95%Molecular weight:282.2 g/molRemdesivir related compound 5
CAS:<p>Remdesivir related compound 5 is a plant extract that inhibits the growth of wheat. Remdesivir related compound 5 contains allelopathy, which is the ability to inhibit the growth of other plants by releasing substances from its roots or leaves. A study was conducted in which wheat seeds were treated with extracts of this plant and it was found that there was a significant decrease in the growth of the plants. This may be due to the inhibition of protein synthesis and cell division, as shown in other studies.</p>Formula:C21H27N2O7PPurity:Min. 95%Molecular weight:450.42 g/molRemdesivir impurity 3 HCl
CAS:<p>Remdesivir impurity 3 HCl is a drug product that is a metabolite of Remdesivir. It has been shown to be a natural, synthetic and research and development impurity standard for HPLC analysis. CAS No.: 2096981-79-0</p>Formula:C9H19NO2·HClPurity:Min. 95%Molecular weight:209.71 g/molRemdesivir related compound 7
CAS:<p>Remdesivir related compound 7 is a drug product that is being synthesized for use in research and development. The synthesis of this compound will be carried out with an analytical purity of greater than 98%. This custom synthesis is not a natural product and has been designed for use in pharmacopoeia. Remdesivir related compound 7 metabolizes to form metabolites that are impurities. It is an API impurity that can be used as a synthetic standard or impurity standard for HPLC testing.</p>Formula:C15H17N5O4Purity:Min. 95%Molecular weight:331.33 g/molDecitabine related compound A
CAS:<p>Decitabine related compound A is an impurity that is found in the API, decitabine. It is an analytical standard for HPLC measurements and a reference material for impurity testing. It is also used as a pharmacopoeia standard for pharmacopoeias such as European Pharmacopoeia, USP, and Japanese Pharmacopoeia. Decitabine related compound A has been synthesized from natural sources such as plant-derived alkaloids and synthetically produced in the laboratory. CAS No. 1019659-87-0</p>Formula:C21H18Cl2O7Purity:Min. 95%Color and Shape:SolidMolecular weight:453.27 g/molSofosbuvir impurity 6
CAS:<p>Sofosbuvir impurity 6 is an impurity in the drug Sofosbuvir. It is a metabolite that is a by-product of the synthesis process of Sofosbuvir, which is used to treat chronic hepatitis C infection. The purity of this compound has been tested with HPLC and found to be 99.99% pure. This compound can also be synthesized from natural or synthetic sources.</p>Formula:C31H27N3O7Purity:Min. 95%Molecular weight:553.56 g/molLamivudine acid
CAS:<p>Lamivudine acid is a synthetic orotate prodrug that is converted to the active form, lamivudine. It inhibits the synthesis of viral DNA by inhibiting the reverse transcriptase enzyme and has been used as a treatment for HIV infection. Lamivudine acid is soluble in organic solvents such as acetone and cyclohexane. The crystal structure of this compound has been determined using X-ray crystallography and exhibits a zwitterion structure with a hydrogen bond between the carboxylate group and the amide nitrogen atom of the molecule.</p>Formula:C8H9N3O4SPurity:Min. 95%Molecular weight:243.24 g/mol2',3'-Isopropylidene ribavirin
CAS:<p>Intermediate in the synthesis of ribavirin</p>Formula:C11H16N4O5Purity:Min. 95%Molecular weight:284.27 g/molRemdesivir impurity 1
CAS:<p>Remdesivir impurity 1 is a drug product, analytical and Metabolism studies. It is a custom synthesis, Impurity standard, Synthetic and Drug development. Remdesivir impurity 1 is an API impurity that is a natural and has CAS No. 1355049-95-4. The HPLC standard of Remdesivir impurity 1 is high purity and pharmacopoeia.</p>Formula:C12H13N5O4Purity:Min. 95%Molecular weight:291.26 g/mol4-Amino-1-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one
CAS:<p>4-Amino-1-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one (4AAT) is an analytical chemical that is used for research and development purposes. 4AAT is a metabolite of the antibiotic ampicillin and has been identified as an impurity in the drug product. It can be synthesized from 2-(4'-chlorophenyl)benzaldehyde, 3,5'-di-O-(4'-chlorobenzoyl)-2',3'-dideoxyribose and sodium azide in a two step process with 98% purity. 4AATs are also found to be present in natural products such as honey or sugar cane juice.</p>Formula:C22H18Cl2N4O6Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:505.31 g/molPteroic acid, min95%
CAS:<p>Pteroic acid is a naturally occurring substance found in plants and animals. It has inhibitory activities against enzymes such as butyrate kinase, acetyl-CoA synthetase, and glutamate dehydrogenase. Pteroic acid is used to synthesize quinoxalines, which are used for the treatment of cancer. Pteroic acid also inhibits cell growth by inhibiting protein synthesis. This is done by conjugating with amino acids and inhibiting their uptake into the ribosome. The inhibition of glutamate dehydrogenase may be due to its ability to reduce levels of glutathione, which is an inhibitor of this enzyme.</p>Formula:C14H12N6O3Purity:Min. 95%Color and Shape:Slightly Yellow PowderMolecular weight:312.28 g/mol1'-Epi gemcitabine, hydrochloride
CAS:<p>Gemcitabine hydrochloride is an analog of the natural nucleoside cytidine. It is a chemotherapeutic drug that is used in the treatment of pancreatic, lung and breast cancer. Gemcitabine hydrochloride is metabolized to its active form by deamination of cytosine residues in DNA. This conversion is catalyzed by the enzyme cytidine deaminase. Gemcitabine hydrochloride has been shown to be effective against metastatic pancreatic cancer and advanced-stage non-small cell lung cancer, as well as early-stage breast cancer. Gemcitabine hydrochloride has also been shown to be effective against certain types of lymphoma and leukemia.</p>Formula:C9H12ClF2N3O4Purity:Min. 95%Molecular weight:299.66 g/molDapagliflozin Impurity 2
CAS:<p>Dapagliflozin impurity 2 is an impurity of dapagliflozin. It has been shown to be metabolized by erythrocytes and to be excreted in urine. Dapagliflozin impurity 2 has been identified in the USP Reference Standard for Dapagliflozin Impurity 2 (1830346-16-1). This material is available for custom synthesis, research, and development.</p>Formula:C15H14BrClOPurity:Min. 95%Molecular weight:325.63 g/mol
![(1R,2S,5R)-Menthol-5R-hydroxy-[1,3]-oxathiolane-2R-carboxylate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM219050.webp&w=3840&q=75)
![9-[[2-Chloroprop-2-en-1-yl)oxy]methyl]guanine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC379785.webp&w=3840&q=75)
![1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIC181108.webp&w=3840&q=75)
![4-Amino-1-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIA74824.webp&w=3840&q=75)
