Sulfonamides and Derivatives
Sulphonamides are compounds that contain a sulphonamide functional group (-SO₂NH₂), where a sulphur atom is bonded to an amino group. They were among the first synthetic antibiotics used in medicine, inhibiting folic acid synthesis in bacteria, which gives them antimicrobial properties. They are mainly used to treat bacterial infections, although their use has declined due to antimicrobial resistance. In addition to their use as antibiotics, sulphonamides also have applications in the treatment of diseases such as malaria and inflammatory bowel diseases.
At CymitQuimica, we offer high-purity sulphonamides and their derivatives for research in microbiology and pharmaceutical development.
Found 2592 products of "Sulfonamides and Derivatives"
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rac Indapamide-d3
CAS:Controlled Product<p>Applications Labelled Indapamide. Used as an antihypertensive. Diuretic.<br>References Leary, et al.: Curr. Ther. Res., 15, 571 (1973), Kyncl, J., et al.: Arzneim.-Forsch., 25, 1491 (1975), DiFeo, T.J., et al.: Anal. Profiles Drug Subs. Excip., 23, 229 (1994),<br></p>Formula:C16H13D3ClN3O3SColor and Shape:White To Light Orange ColorMolecular weight:368.858-Methylquinoline
CAS:<p>Applications 8-Methylquinoline is used in QSAR treatment of mutagenicity and cytotoxicity of quinolines.<br>References Smith, C. J., et al.: Mutat. Res., Fund. Mol. Mech. Mut., 379, 167 (1997)<br></p>Formula:C10H9NColor and Shape:Light Yellow LiquidMolecular weight:143.1854’-Hydroxyacetophenone Oxime
CAS:Controlled Product<p>Impurity Paracetamol EP Impurity G<br>Applications 4’-Hydroxyacetophenone Oxime is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Sengupta, S., et al.: Metal. Based Drugs, 8, 293 (2002) (2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)<br></p>Formula:C8H9NO2Color and Shape:NeatMolecular weight:151.16Gliclazide-d4
CAS:Controlled ProductFormula:C152H4H17N3O3SColor and Shape:White To Off-WhiteMolecular weight:327.44Tosylurethane
CAS:Controlled Product<p>Impurity Gliclazide EP Impurity C<br>Applications Tosylurethane (Gliclazide EP Impurity C) is an intermediate in the synthesis of Gliclazide (G409877), a sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972); Holmes, B., et al.: Drugs, 27, 301 (1984)<br></p>Formula:C10H13NO4SColor and Shape:Off WhiteMolecular weight:243.284-Amino-6-chloro-1,3-benzenedisulfonamide
CAS:Controlled Product<p>Impurity Hydrochlorothiazide EP Impurity B<br>Applications Diuretic. Hydrochlorothiazide EP Impurity B.<br>References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Joshi, S., et al.: J. Pharm. Biomed. Anal., 52, 362 (2010), Castillo-Garit, J., et al.: Eur. J. Pharm. Sci., 39, 30 (2010),<br></p>Formula:C6H8ClN3O4S2Color and Shape:White To Light BrownMolecular weight:285.73Sulfacetamide-d4
CAS:Controlled Product<p>Applications Sulfacetamide-d4 is the isotope labelled analog of Sulfacetamide. Sulfacetamide is an antibiotic used for the treatment of skin infections and urinary tract infections. Sulfacetamide is also used to treat acne and seborrheic dermatitis. Sulfacetamide was investigated for potential anti-inflammatory properties<br>References Wittwer, M.B., et al.: J. Med. Chem., 56, 781 (2013); Wang. X., et al.: Afr. J. Micriobiol., 6, 4533 (2012); Yu, B., et al.: Euro. J. Med. Chem., 46, 5833 (2011);<br></p>Formula:C8H6D4N2O3SColor and Shape:NeatMolecular weight:218.27Acetaminophen-13C2, 15N1
CAS:Controlled Product<p>Applications Acetaminophen-13C2, 15N1 is doubly labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C613C2H915NO2Color and Shape:WhiteMolecular weight:154.14Sulfamethoxazole β-D-Glucuronide
CAS:<p>Applications The main metabolite of Sulfamethoxazole.<br>References Altenburger, R., et al.: Environ. Toxicol. Chem., 19, 2341 (2000), Pascoe, R., et al.: Anal. Chem., 73, 6014 (2001), Zhaohua, H., et al.: Eur. J. Med. Chem., 36, 863 (2001),<br></p>Formula:C16H19N3O9SColor and Shape:NeatMolecular weight:429.40p-Butyl Ibuprofen (~90%)
CAS:Controlled ProductFormula:C13H18O2Purity:~90%Color and Shape:NeatMolecular weight:206.28Ibuprofen Piconol
CAS:Controlled Product<p>Applications Ibuprofen Piconol is an anti-inflammatory agent that can be synthesized from Ibuprofen (I140000), which is a selective cyclooxygenase inhibitor.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); Xiang, L., et al.: Huaxi Yaoxue Zazhi, 21, 178 (2006); Chem. and Eng. News p9, July 4 (2016);<br></p>Formula:C19H23NO2Color and Shape:NeatMolecular weight:297.394'-Isobutylacetophenone
CAS:Controlled Product<p>Impurity Ibuprofen EP Impurity E<br>Applications 4'-Isobutylacetophenone (Ibuprofen EP Impurity E) is a degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reynolds, D., et al.: Pharm. Technol., 26, 48 (2002), Wasylaschuk, W., et al.: J. Pharm. Sci., 96, 106 (2007),<br></p>Formula:C12H16OColor and Shape:Colourless To Light YellowMolecular weight:176.25rac Indapamide
CAS:<p>Applications Used as an antihypertensive. Diuretic.<br>References Leary, et al.: Curr. Ther. Res., 15, 571 (1973), Kyncl, J., et al.: Arzneim.-Forsch., 25, 1491 (1975), DiFeo, T.J., et al.: Anal. Profiles Drug Subs. Excip., 23, 229 (1994),<br></p>Formula:C16H16ClN3O3SColor and Shape:White To Off-WhiteMolecular weight:365.833-[4-(2-Pyridylsulfamoyl)phenyl] Sulfasalazine
CAS:Controlled Product<p>Applications An impurity of Sulfasalazine (S699084).<br></p>Formula:C29H22N6O7S2Color and Shape:NeatMolecular weight:630.65rac Ibuprofen
CAS:Controlled Product<p>Applications A selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Ibuprofen has has been shown to reduce Ebola infection in rodents (4).This compound is a contaminant of emerging concern (CECs).<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); (4) Chem. and Eng. News p9, July 4 (2016);<br></p>Formula:C13H18O2Color and Shape:NeatMolecular weight:206.28Ethyl 2-Bromoisovalerate
CAS:<p>Applications Ethyl 2-Bromoisovalerate (cas# 609-12-1) is a compound useful in organic synthesis.<br></p>Formula:C7H13BrO2Color and Shape:NeatMolecular weight:209.08Indomethacin-d4
CAS:Controlled Product<p>Applications Nonsteroidal anti-inflammatory agent (NSAID).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Formula:C192H4H12ClNO4Color and Shape:White To Off-WhiteMolecular weight:361.81Brinzolamide
CAS:Controlled Product<p>Applications Carbonic anhydrase inhibitor. Antiglaucoma agent.<br>References Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, 99, 276 (2002),<br></p>Formula:C12H21N3O5S3Color and Shape:NeatMolecular weight:383.51N-Hydroxy Sulfamethoxazole
CAS:Controlled Product<p>Applications A Sulfamethoxazole metabolite.<br>References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),<br></p>Formula:C10H11N3O4SColor and Shape:NeatMolecular weight:269.282-(4-Chloro-3-sulfobenzoyl)-benzoic Acid
CAS:Controlled Product<p>Applications 2-(4-Chloro-3-sulfobenzoyl)-benzoic Acid is an impurity of Chlorthalidone (C427500) which is used as a diuretic.<br>References Beisenherz, et al.: Arch. Int. Pharmacodyn. Ther., 161, 76 (1966); Zsoter, et al.: J. Pharmacol. Exp. Ther., 180, 723 (1972); Singer, J.M., et al.: Anal. Profiles Drug Subs., 14, 1 (1985)<br></p>Formula:C14H9ClO6SColor and Shape:NeatMolecular weight:340.74Phthalide
CAS:Controlled Product<p>Applications Phthalide may be used in scaffolds for the design of high potency monoamine oxidase (MAO) inhibitors.<br>References Li, P.Z., et. al.: Med. Chem. Res., 23, 3624 (2014)<br></p>Formula:C8H6O2Color and Shape:ColourlessMolecular weight:134.13(R)-(-)-Ibuprofen
CAS:Controlled Product<p>Applications A nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formula:C13H18O2Color and Shape:White SolidMolecular weight:206.282,4-Dichloro-5-sulfamoylbenzoic Acid
CAS:Controlled Product<p>Impurity Furosemide EP Impurity B<br>Applications 2,4-Dichloro-5-sulfamoylbenzoic Acid is a chlorinated sulfamoylbenzoic acid with diuretic acid.<br>References Shani, J. et al.: Pharmacology, 26, 172 (1983); Lebedev, A.A. et al.: Khim.-Farm. Zhur., 19, 1205 (1985);<br></p>Formula:C7H5Cl2NO4SColor and Shape:WhiteMolecular weight:270.09Hydroflumethiazide
CAS:Controlled Product<p>Applications Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Formula:C8H8F3N3O4S2Color and Shape:NeatMolecular weight:331.29Methiocarb Sulfone
CAS:<p>Applications Methiocarb Sulfone is a pesticide which is used in the protection of crops from insects and fungus.<br>References Wong, J. et al.: J. Agri,. Food. Chem., 58, 5897 (2010); Ghini, S. et al.: Arch. Env. Cont. Toxicol., 47, 479 (2004);<br></p>Formula:C11H15NO4SColor and Shape:Colourless SolidMolecular weight:257.31Furosemide-d5
CAS:Controlled Product<p>Applications Labelled Furosemide (F865000). Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Benet, L.Z.: J. Pharmacokinet. Biopharm., 7, 1 (1979)<br></p>Formula:C12D5H6ClN2O5SColor and Shape:WhiteMolecular weight:335.77Tetraethyleneglycol Bisibuprofen Ester
CAS:<p>Applications Tetraethyleneglycol Bisibuprofen Ester is an impurity of ibuprofen (rac, I140000) which is a selective cyclooxygenase inhibitor. It inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>Formula:C34H50O7Color and Shape:Colourless To Light BrownMolecular weight:570.7573-Chloro-2-methylaniline
CAS:Formula:C7H8ClNColor and Shape:Light Yellow To Light BrownMolecular weight:141.60Ibuprofen Sodium Salt Dihydrate
CAS:Controlled ProductFormula:C13H17O2·2H2O·NaColor and Shape:NeatMolecular weight:264.293N-Acetyl Zonisamide
CAS:Controlled Product<p>Applications A metabolite of Zonisamide (Z700000), a new anticonvulsant.<br>References Perchalski, R. J., et al.: J. Clin. Pharmacol., 26, 435 (1986), Stiff, D.D., et al.: Drug Metab. Disp., 18, 888 (1990),<br></p>Formula:C10H10N2O4SColor and Shape:NeatMolecular weight:254.26(R)-(-)-Ibuprofen-d3
CAS:Controlled Product<p>Applications A labelled nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formula:C13H15D3O2Color and Shape:NeatMolecular weight:209.3N-(p-Toluenesulfonyl)urea
CAS:<p>Applications N-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.<br>References Hellman, B., et al.: Metabol. Clinc. Experiment., 23, 839 (1974); Tozuka, Z., et al.: J. Pharma. Sci., 100, 4024 (2011);<br></p>Formula:C8H10N2O3SColor and Shape:NeatMolecular weight:214.242α-(4-Isobutylphenyl)ethanol
CAS:<p>Applications The photodegradation product of Ibuprofen (I140000). Shows cytotoxicity activity.<br>References Kobayashi, S., et al.: Biochemistry, 23, 4589 (1984), Karthein, R., et al.: Eur. J. Biochem., 171, 313 (1988), Maranon, M., et al.: Phytochem., 37, 1217 (1994),<br></p>Formula:C12H18OColor and Shape:Colourless LiquidMolecular weight:178.27Trimethoprim-13C3
CAS:Controlled Product<p>Applications Antibacterial.<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Formula:C3C11H18N4O3Color and Shape:NeatMolecular weight:293.30N-Methylsulfonyl Nimesulide
CAS:<p>Impurity Nimesulide EP Impurity F<br>Applications N-Methylsulfonyl Nimesulide is an impurity of Nimesulide (N477500).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kulkarni, S., et al.: Curr. Sci., 83, 1442 (2002), Nguyen, D., et al.: J. Sep. Sci., 29, 1836 (2006), Zacharis, C., et al.: J. Pharm. Biomed. Anal., 49, 726 (2009),<br></p>Formula:C14H14N2O7S2Color and Shape:NeatMolecular weight:386.40Ibuprofen Acyl-β-D-glucuronide (mixture of diastereomers)
CAS:<p>Stability Hygroscopic, Not stable in aqueous solutions.<br>Applications Ibuprofen Acyl-β-D-glucuronide (mixture of diastereomers) (cas# 115075-59-7) is a compound useful in organic synthesis.<br></p>Formula:C19H26O8Color and Shape:NeatMolecular weight:382.408-Desethyl Etodolac
CAS:Controlled Product<p>Impurity Etodolac EP Impurity A<br>Applications 8-Desethyl Etodolac (Etodolac EP Impurity A) is an impurity of Etodolac (E933100) which was examined for mutagenicity in reverse mutation tests on bacteria. Etodolac impurity A.<br>References Franke, L., et al.: J. Med. Chem., 48, 6997 (2005), Fox, T., et al.: Curr. Top Med. Chem., 6, 1579 (2006),<br></p>Formula:C15H17NO3Color and Shape:NeatMolecular weight:259.30Glipizide
CAS:Controlled Product<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ambrogi, et al.: Arzneimittel-Forsch., 21, 200 (1971), Fuccella, et al.: J. Clin. Pharmacol., 13, 68 (1973), Brogden, R.N., et al.: Drugs, 18, 329 (1979), Lebovitz, H.E., et al.: Pharmacother., 5, 63 (1985)<br></p>Formula:C21H27N5O4SColor and Shape:WhiteMolecular weight:445.54Metazachlor
CAS:Controlled Product<p>Applications A chloroacetanilide herbicide used on vegetable crops.<br>References Matthies, M., et al.: Environ. Sci. Technol., 43, 9223 (2009); Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009); Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010); Liu, B., et al.: J. Agric. Food Chem., 58, 2673 (2010);<br></p>Formula:C14H16ClN3OColor and Shape:Off White To Light BeigeMolecular weight:277.752-Aminopyrimidine
CAS:<p>Applications 2-Aminopyrimidine is used in the synthesis of sulfonamides as isoform-selective inhibitors with efficacy in rodent pain models.<br>References Focken, T. et al.: ACS Med. Chem., 7, 277 (2016); Reddy, M. et al.: Bioorg. Med. Chem., 24, 521 (2016);<br></p>Formula:C4H5N3Color and Shape:NeatMolecular weight:95.10N-Acetyl Sulfamethoxazole-d4 (major)
CAS:Controlled ProductFormula:C122H4H9N3O4SColor and Shape:Light Orange Light BrownMolecular weight:299.34Diethyl Carbonate
CAS:Controlled Product<p>Applications Diethyl Ester Carbonic Acid is used in the synthesis of 2-oxooxazolidines as antibacterials. Also used in the synthesis of donepezil/huperzine fragments as acetylcholinesterase inhbitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gregory, W. et al.: J. Med. Chem., 32, 1673 (1989); Bioorg. Med. Chem., 21, 676 (2013);<br></p>Formula:C5H10O3Color and Shape:Colourless To Light YellowMolecular weight:118.034-(2-Methylpropyl)benzeneethanol
CAS:Controlled ProductFormula:C12H18OColor and Shape:NeatMolecular weight:178.27Triclocarban-d4 (4-chlorophenyl-d4)
CAS:Controlled Product<p>Applications Triclocarban-d4 (4-chlorophenyl-d4) (CAS# 1219799-29-7) is a useful isotopically labeled research compound.<br></p>Formula:C132H4H5Cl3N2OColor and Shape:Off-WhiteMolecular weight:319.614-Acetylamino-2-chlorophenol
CAS:Controlled Product<p>Impurity Paracetamol EP Impurity C/ Acetaminophen impurity C<br>Applications 4-Acetylamino-2-chlorophenol is an impuirty of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C8H8ClNO2Color and Shape:White To Light PurpleMolecular weight:185.61O-Desmethyl Indomethacin
CAS:Controlled Product<p>Applications The major metabolite of Indomethacin.<br>References Lewis, R., et al.: J. Clin. Invest., 53, 1607 (1974), Alvan, G., et al.: Clin. Pharmacol. Ther., 18, 364 (1975), Mungall, D., et al.: J. Pharm. Sci., 73, 1000 (1984), Baldwin, S., et al.: Xenobiotica, 25, 261 (1995),<br></p>Formula:C18H14ClNO4Color and Shape:NeatMolecular weight:343.76
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