Sulfonamides and Derivatives
Sulphonamides are compounds that contain a sulphonamide functional group (-SO₂NH₂), where a sulphur atom is bonded to an amino group. They were among the first synthetic antibiotics used in medicine, inhibiting folic acid synthesis in bacteria, which gives them antimicrobial properties. They are mainly used to treat bacterial infections, although their use has declined due to antimicrobial resistance. In addition to their use as antibiotics, sulphonamides also have applications in the treatment of diseases such as malaria and inflammatory bowel diseases.
At CymitQuimica, we offer high-purity sulphonamides and their derivatives for research in microbiology and pharmaceutical development.
Found 2592 products of "Sulfonamides and Derivatives"
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Cotrimoxazole
CAS:<p>Applications Cotrimoxazole is an antibiotic. Pseudomonas aeruginosa has a drug resistant rate of 66% in the years 2010-2013.<br>References Sun, D., et. al.: Zhonghua Yiyuanganranxue Zazhi, 24, 345 (2014)<br></p>Formula:C24H29N7O6SColor and Shape:NeatMolecular weight:543.63,4,4'-Trichlorocarbanilide(Triclocarban)
CAS:Controlled ProductFormula:C13H9Cl3N2OColor and Shape:White Crystalline PowderMolecular weight:315.58Dimethyl n-methylsulfamide
CAS:Purity:97.0%Color and Shape:Liquid, ClearMolecular weight:138.19000244140625Decarboxy Etodolac
CAS:Controlled Product<p>Impurity Etodolac EP Impurity J<br>Applications Decarboxy Etodolac (Etodolac EP Impurity J) is an impurity of Etodolac (racemic, E933100), which is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2). Etodolac displays anti-inflammatory effects in both adjuvant arthritic and normal rats. Etodolac is anti-inflammatory.<br>References Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987); Balfour, J.A, et al.: Drugs, 42, 274 (1991); Kato, et al.: J. Pharm. Pharmacol., 53 1679 (2001)<br></p>Formula:C16H21NOColor and Shape:White To YellowMolecular weight:243.342-Chlorobenzoic Acid
CAS:<p>Impurity Mesalazine EP Impurity L<br>Applications The toxicity of halogenated benzoic acids was found to be directly related to the compound's hydrophobicity. Toxicity and quantitative structure-activity relationships of benzoic acids to Pseudokirchneriella subcapitata.<br>References Moore, D., et al.: Environ. Toxicol. Chem., 16, 794 (1997), Zhao, Y., et al.: Sci. Total Environ., 216, 205 (1998), Fiorentino, A., et al.: J. Agric.Food Chem., 51, 1005 (2003),<br></p>Formula:C7H5ClO2Color and Shape:NeatMolecular weight:156.572,7-Diamino-6-phenyl-4-pteridinol
CAS:Controlled Product<p>Impurity Triamterene EP Impurity B/ Triamterene USP Related Compound B<br>Applications 2,7-Diamino-6-phenyl-4-pteridinol has potential as a pteridine diuretic. Impurity in the synthesis of Triamterene (T767325), a weak diuretic with potassium sparing properties; blocks Na+ reuptake in the kidneys.<br>References Osdene, et al.: J. Med. Chem., 10, 431 (1967), Kapoor, V.K., et al.: Anal. Profiles Drug Subs. Excip., 23, 571 (1994); Weinstock, J. et al.: J. Med. Chem., 11, 573 (1968);<br></p>Formula:C12H10N6OColor and Shape:NeatMolecular weight:254.25Mordant Yellow 10 (Technical Grade)
CAS:Controlled Product<p>Impurity Sulfasalazine Impurity I<br>Stability Light Sensitive<br>Applications Mordant Yellow 10 is a monoazo dye used in wool textiles. Mordant Yellow 10 is used as organic reagent for spectrometric determination of iron(III) as well as in the study of other metal complexations.<br>References Ledneva, I.A. Izvest. Vyssh. Ucheb. Zav. Tekh. Teks. Prom., 5, 58 (1986); Vladescu, L. et al.: Rev. Roum. Chem., 54, 85 (2009); Gupta, P.N. et al.: Asian J. Chem., 4, 15 (1992);<br></p>Formula:C13H8N2O6S·2NaColor and Shape:NeatMolecular weight:366.264-Acetaminophen-d3 Sulfate
CAS:Controlled Product<p>Applications 4-Acetaminophen-d3 Sulfate is deuterium labeled metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961) (2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Formula:C82H3H6NO5SColor and Shape:White To Off-WhiteMolecular weight:234.243-Hydroxyacetaminophen
CAS:Controlled Product<p>Applications 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)<br></p>Formula:C8H9NO3Color and Shape:NeatMolecular weight:167.16(3RS)-1,3-Bis[4,-2-(methylpropyl)phenyl]butan-1-one
CAS:Controlled ProductFormula:C24H32OColor and Shape:Colourless To Light YellowMolecular weight:336.51Tolbutamide-d9
CAS:Controlled ProductFormula:C122H9H9N2O3SColor and Shape:White To Off-WhiteMolecular weight:279.40Sulfathiazole
CAS:Controlled Product<p>Applications Antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Kapoor, V.K., et al.: Anal. Profiles Drug Subs. Excip., 22, 389 (1993),<br></p>Formula:C9H9N3O2S2Color and Shape:WhiteMolecular weight:255.325-Amino-1,3,4-thiadiazole-2-sulfonamide Hydrochloride Salt
CAS:Controlled Product<p>Impurity Acetazolamide EP Impurity D Hydrochloride<br>Applications Acetazolamide intermediate. (Acetazolamide EP Impurity D Hydrochloride)<br>References Carta, F., et al.: Bioorg. Med. Chem. Lett., 19, 6649 (2009), Joseph, P., et al.: J. Med. Chem., 53, 2277 (2010), Srinivasu, P., et al.: J. Pharm. Biomed. Anal., 52, 142 (2010),<br></p>Formula:C2H5ClN4O2S2Color and Shape:NeatMolecular weight:216.67Trimethoprim-d3
CAS:Controlled Product<p>Applications Deuterated Trimethoprim, an antibacterial.<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Formula:C14D5H15N4O3Color and Shape:Off WhiteMolecular weight:297.3643-Oxo-1,2-benzoisothiazoline-2-acetic Acid Methyl Ester 1,1-Dioxide
CAS:<p>Impurity Piroxicam EP Impurity D<br>Applications Piroxicam impurity D.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Formula:C10H9NO5SColor and Shape:NeatMolecular weight:255.25Ibuprofen Alcohol
CAS:Controlled Product<p>Applications Ibuprofen Alcohol (Ibuprofen EP Impurity P) is an impurity of Ibuprofen (I140000). Ibuprofen impurity P as per EP.<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Zhao, J., et al.: Anal. Chem., 72, 302 (2000), Kucera, R., et al.: J. Pharm. Biomed. Anal., 38, 609 (2005),<br></p>Formula:C13H20OColor and Shape:Colourless To Light YellowMolecular weight:192.306,6'-Oxybis-2-naphthalenesulfonic Acid Disodium Salt (>85%)
CAS:Controlled Product<p>Applications An impurity contained in the commercial food Yellow No.5 (Sunset Yellow FCF) which has a potent mutagenicity effect.<br>References Yamada, M., et al.: Chem. Pharm. Bull., 44, 1624 (1996), Yamada, M., et al.: J. Food Chem., 3, 151 (1996),<br></p>Formula:C20H12O7S2·2NaPurity:>90%Color and Shape:White To Light GreyMolecular weight:474.41Glimepiride
CAS:<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ratheiser, K., et al.: Arzneim.-Forsch., 43, 856, (1993),<br></p>Formula:C24H34N4O5SColor and Shape:NeatMolecular weight:490.624-Nitro Sulfamethoxazole
CAS:Controlled Product<p>Applications A Sulfamethoxazole metabolite.<br>References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),<br></p>Formula:C10H9N3O5SColor and Shape:Light BrownMolecular weight:283.263-Desmethyl Trimethoprim
CAS:Controlled Product<p>Applications 3-Desmethyl Trimethoprim is a metabolite of Trimethoprim (T795615); an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections. 3-Desmethyl Trimethoprim gets excreted in the urine of rats, dogs, and man in the form of glucuronides.<br>References Roth, B., et al.: J. Med. Chem., 24, 933 (1981); Liu, Z., et al.: Biomed. Chromatogr., 26, 1101 (2012); Schwartz, D. E., Arzneimittel-Forsch., 20, 1867 (1970)<br></p>Formula:C13H16N4O3Color and Shape:White To Light BrownMolecular weight:276.29Diacetic Aceclofenac
CAS:Controlled Product<p>Impurity Aceclofenac EP Impurity H<br>Applications A 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative as anti-inflammmatory and analgesic agent. (Aceclofenac EP Impurity H)<br></p>Formula:C20H17Cl2NO8Color and Shape:White To Off-WhiteMolecular weight:470.26Terizidone
CAS:Controlled Product<p>Applications A drug used to treat tuberculosis.<br>References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005),<br></p>Formula:C14H14N4O4Color and Shape:NeatMolecular weight:302.294-Hydroxy Trimethoprim
CAS:<p>Applications Trimethoprim (T795615) derivative. Antibacterial properties.<br></p>Formula:C14H18N4O4Color and Shape:NeatMolecular weight:306.32Pyroxasulfone
CAS:Controlled Product<p>Applications Pyroxasulfone is an inhibitor of the biosynthesis of very-long-chain fatty acids. Pyroxasulfone is also used to control grass weed species in pre-emergence in major field crops.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Busi, R., et al.: Pest. Manag. Sci., 72, 1665 (2016)<br></p>Formula:C12H14F5N3O4SColor and Shape:WhiteMolecular weight:391.31Napropamid
CAS:<p>Applications Napropamid is used as a pesticide.<br>References She-feng, J., et al.: Nanjing Nongye Daxue Xuebao, 35, 137 (2012);<br></p>Formula:C17H21NO2Color and Shape:Light Orange Color To Light BrownMolecular weight:271.35Phenacetin
CAS:Controlled Product<p>Applications Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959), Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983),<br></p>Formula:C10H13NO2Color and Shape:WhiteMolecular weight:179.22Despyridyl Piroxicam (Piroxicam Impurity C)
CAS:Controlled ProductFormula:C10H10N2O4SColor and Shape:NeatMolecular weight:254.261,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester
CAS:<p>Impurity Etodolac EP Impurity K<br>Applications 1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester (Etodolac EP Impurity K) is a derivative of Etodolac.<br>References Caldwell, J., et al.: Biochem. Pharmacol., 37, 105 (1988), Drummer, O., et al.: J. Anal. Toxicol., 17, 225 (1993)<br></p>Formula:C18H23NO3Color and Shape:White To Off-WhiteMolecular weight:301.38Diclosan
CAS:<p>Applications Diclosan is used in the treatment of halogenated phenolic compounds by sequential tri-metal reduction and laccase-catalytic oxidation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dai, Y., et al.: Water Res., 71, 64 (2015);<br></p>Formula:C12H8Cl2O2Color and Shape:White PowderMolecular weight:255.10Acetanilide (Acetylaniline)
CAS:Controlled Product<p>Impurity Paracetamol EP Impurity D<br>Applications Acetanilide (Acetylaniline) the first aniline derivative found to possess analgesic and antipyretic properties (1,2). It is also an impurity of Acetaminophen (A161220).<br>References (1) Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010) (2) Chang, C., et al.: J. Nat. Prod., 73, 229 (2010)<br></p>Formula:C8H9NOColor and Shape:White To Light BrownMolecular weight:135.16Furosemide
CAS:Controlled Product<p>Applications Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic. Non-competitve subtype-specific blocker of GABAA. Neuroprotective & Neuroresearch Products.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Benet, L.Z.: J. Pharmacokinet. Biopharm., 7, 1 (1979); Korpi, E. et al.: Mol. Pharmacology, 47, 283 (1995);<br></p>Formula:C12H11ClN2O5SColor and Shape:White To Off-WhiteMolecular weight:330.74Niflumic Acid
CAS:Controlled Product<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Formula:C13H9F3N2O2Color and Shape:Light YellowMolecular weight:282.22Ibuprofen Carboxylic Acid(Mixture of Diastereomers)
CAS:Controlled Product<p>Applications The major metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes.<br>References Bhuyan, K., et al.: Life Sci., 38, 1463 (1986), Blakytny, R., et al.: Biochem. J., 288, 303 (1992),Ganea, E., et al.: Eur. J. Biochem., 231, 181 (1995), Mitchell, J., et al.: Br. J. Pharmacol., 128, 1121 (1999),<br></p>Formula:C13H16O4Color and Shape:White SolidMolecular weight:236.264'-Isopropylacetophenone
CAS:Controlled ProductFormula:C11H14OColor and Shape:NeatMolecular weight:162.234-Acetamidobenzenesulfonic Acid
CAS:Controlled Product<p>Impurity Sulfadimethoxine EP Impurity C<br>Stability Hygroscopic<br>Applications 4-Acetamidobenzenesulfonic Acid (Sulfadimethoxine EP Impurity C) is a metabolite of Sulfanilic acid.<br>References Saab, N., et al.: Eur. J. Med. Chem., 34, 745 (1999), Kim, H., et al.: J. Pharm. Biomed. Anal., 27, 51 (2002), Santelli-Rouvier, C., et al.: Eur. J. Med. Chem., 39, 735 (2004),<br></p>Formula:C8H9NO4SColor and Shape:NeatMolecular weight:215.23Benzylhydrochlorothiazide
CAS:Controlled ProductFormula:C14H14ClN3O4S2Color and Shape:NeatMolecular weight:387.86Hydroflumethiazide-13CD2
CAS:Controlled Product<p>Applications Labelled Hydroflumethiazide. Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Formula:C713CH6D2F3N3O4S2Color and Shape:NeatMolecular weight:334.30rac 1-Nitroso-2-methylindoline
CAS:Controlled ProductFormula:C9H10N2OColor and Shape:BrownMolecular weight:162.19N-Nitroso Furosemide ( >80%)
CAS:Formula:C12H10ClN3O6SPurity:>80%Color and Shape:Light Orange To Dark OrangeMethyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide
CAS:Controlled Product<p>Impurity Piroxicam EP Impurity G<br>Applications Piroxicam impurity G.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Pharmacol., 36, 79 (1996), Bihovsky, R., et al.: Bioorg. Med. Chem. Lett., 14, 1035 (2004),<br></p>Formula:C10H9NO5SColor and Shape:NeatMolecular weight:255.254-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-2(1H)-pyrimidinone
CAS:Controlled Product<p>Impurity USP Trimethoprim Related Compound A<br>Applications 6-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-2(1H)-pyrimidinone, is an impurity of Trimethoprim (T795615), an antibacterial agent.<br>References Popov, V. M., et al.: Bioorg. Med. Chem. Lett., 16, 4366 (2006); Brogden, R.N., et al.: Drugs, 23, 405 (1982);<br></p>Formula:C14H17N3O4Color and Shape:WhiteMolecular weight:291.30Glimepiride-d5
CAS:Controlled Product<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ratheiser, K., et al.: Arzneimittel-Forsch., 43, 856, (1993),<br></p>Formula:C24H29D5N4O5SColor and Shape:Off-WhiteMolecular weight:495.65Dehydro Indapamide
CAS:Controlled Product<p>Impurity Indapamide USP Related Compound A/ Indapamide EP Impurity B<br>Applications A metabolite of Indapamide (M5). A dehydrogenation pathway by cytochromes P450. Indapamide USP Related Compound A<br>References Tamura A., et al.: Chem. Pharm. Bull., 38, 225 (1990), Harlow, G.R., et al.: J. Biol. Chem., 272, 5396 (1997), Ozden, T., et al.: Pharm. Pharmacol. Commun., 4, 397 (1998), Gruciani, G., et al.: J. Med. Chem., 48, 6970 (2005), Sun, H., et al.: Drug. Metab. Dispos., 37, 672 (2009),<br></p>Formula:C16H14ClN3O3SColor and Shape:White To Light BrownMolecular weight:363.823-Nitro-4-phenoxy-5-sulfamoylbenzoic Acid
CAS:<p>Impurity Bumetanide Impurity A<br>Applications 3-Nitro-4-phenoxy-5-sulfamoylbenzoic Acid is a compound related to Piretanide (P508700) and an intermediate in the production of Bumetanide, Bumetanide Impurity A (B689550).<br></p>Formula:C13H10N2O7SColor and Shape:NeatMolecular weight:338.29Ibuprofen Dimer
CAS:Controlled Product<p>Impurity Ibuprofen EP Impurity G<br>Applications Ibuprofen Dimer (Ibuprofen EP Impurity G) is a dimer impurity of Ibuprofen (I140000).<br></p>Formula:C26H32O4Color and Shape:Light Orange ColourMolecular weight:408.53rac Ibuprofen-d3
CAS:Controlled Product<p>Applications Labelled Ibuprofen, a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formula:C132H3H15O2Color and Shape:Off-WhiteMolecular weight:209.30Bis(4-hydroxyphenyl) Sulfone
CAS:Controlled Product<p>Applications Bis(4-hydroxyphenyl) Sulfone is commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin.<br>References Fu, J.W., et al.: Adv. Mat. Rsch., 266, 1022 (2011); Li, J.X., et al.: Polymers. Adv. Tech., 23, 803 (2012);<br></p>Formula:C12H10O4SColor and Shape:WhiteMolecular weight:250.274-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide
CAS:<p>Impurity Glimepiride EP Impurity B/ USP Glimepiride Related Compound B<br>Applications 4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide (Glimepiride EP Impurity B) is an intermediate for the preparation of Glimepiride.<br></p>Formula:C16H21N3O4SColor and Shape:Off-WhiteMolecular weight:351.42
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