Food Industry Standards

<p>Applications Hexacosanoic Acid (cas# 506-46-7) is a compound useful in organic synthesis.<br></p>

<p>Applications A metabolite of Nefazodone (N389100), a novel antidepressant.<br>References Myol, R., et al.: Clin. Pharmacol. Ther., 37, 210 (1985), Haria, M., et al.: Drugs Aging, 4, 331 (1994), Kalgutkar, A., et al.: Drug Metab. Dispos., 33 243 (2005),<br></p>

<p>Applications Diphenyl Phthalate-3,4,5,6-d4 (CAS# 1398065-61-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications (2-Decyl)benzene is a linear alkylbenzene used to synthesize aryl olefins.<br>References Faghihian, H., et al.: App. Surface. Sci., 264, 492 (2013);<br></p>

<p>Applications Isotope labelled Diundecyl Phthalate is a phthalate diester and has been investigated for its toxicology in male rats for risk assessment.<br>References Kwack, S.J., et al.: J. Toxicol. Environ. Health., 72, 1446 (2009); Serafimova, R., et al.: Chem. Res. Toxiciol., 20, 662 (2007);<br></p>

<p>Applications Tributyl Trimellitate (cas# 1726-23-4) is a useful research chemical.<br></p>

<p>Applications Tricosanoic Acid is a saturated fatty acid. It may be used to activate orphan G protein-coupled receptor GPR40.<br>References Briscoe, C., et al.: J. Biol. Chem., 278, 11303 (2003)<br></p>

<p>Applications Dimethyl Terephthalate-2,3,5,6-d4 (CAS# 74079-01-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Eriodictyol is used in biological studies as natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation. Eriodictyl is extracted from Yerba santa, an herb. The leaf is used to make medicine.Yerba santa is used for respiratory conditions including coughs, colds, tuberculosis, asthma, and chronic bronchitis. It is also used for fever and dry mouth. Some people use it to relieve muscle spasms, to loosen phlegm, and as a tonic.<br>References Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012)<br></p>

<p>Applications 1,​9-​Decadiene is used in acyclic diene metathesis copolymerization (ADMET) along with 1, 5-hexadiene to form polybutadiene –polyoctenamer copolymers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wagener, K.B., et al.: Macromolecules, 23, 5155-57 (1990);<br></p>

<p>Applications (1R,​4S)​-1,​3,​3-​Trimethylbicyclo[2.2.1]​heptan-​2-​one also known more commonly as (-)-Fenchone is a chiral intermediate of Fenchone and is currently being used for studies ranging from inhibitory effects of monoterpenes on human TRPA1 and odorant receptor of the malaria vector Anopheles gambiae.<br>References Rahman, S., et al. J. Biol. Chem., 292, 18916-23 (2017); Takaishi, M., et al.: J Physio. Sci., 64, 47-57 (2014)<br></p>

<p>Applications Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells.<br>References Lee, H., et al.: J. Immunol., 185, 6698 (2010); Hsieh, T.J., et al.: Food. Chem. Toxicol., 42, 843 (2004);<br></p>

<p>Applications (1,2-Dioxoethylene)bis(iminoethylene) bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate) (cas# 70331-94-1) is a useful research chemical.<br></p>

<p>Applications A component of garlic which revealed antiplatelet, antithrombotic activity and reduced LDL oxidation thus indicating their possible use for cardiovascular disease.<br>References Steinberg, D., et al.: J. Biol. Chem., 272, 20963 (1997), Lawson, L., et al.: J. Agric. Food Chem., 53, 6254 (2005), Gonen, A., et al.: Pathobiology, 72, 325 (2005),<br></p>

<p>Applications Methacrylamide (cas# 79-39-0) is a useful research chemical.<br></p>

<p>Applications trans-p-Methoxycinnamaldehyde is used in the food industry as a flavor and fragrance agent. It also acts as a nematicidal agent in certain organisms.<br>References Kawashima, Y. et al.: Foods. Food. Ingred. J. Jpn., 169, 29 (1996); Kong, J.O. et al.: J. Nematol., 39, 31 (2007);<br></p>

<p>Stability Hygroscopic<br>Applications A glucuronide conjugate of the phthalate ester metabolite Monomethyl Phthalate (M566540).<br>References Thompson, R.M. et al.: Drug Metab. Disp., 1, 489 (1973);<br></p>

<p>Applications A reagent for high performance polymer research.<br>References Fouassier, J., et al.: Polymer, 36, 5005 (1995),<br></p>

<p>Applications 17-epi-10-Deacetyl Baccatin III is an impurity of Paclitaxel (P132500) and derivatives.<br>References Hu, S., et al.: Biocatal. Biotransform., 14, 241 (1997), Sun, D., et al.: Bioorg. Med. Chem., 9, 1985 (2001),<br></p>

<p>Applications Triphenylphosphine is used in the synthesis of Chlorambucil with cytotoxicity in breast and pancreatic cancers. Also used in the preparation of α-Tocopherol analogues for monitoring antioxidant status.<br>References Millard, M. et al.: J. Med. Chem., 56, 9170 (2013); Krumova, K. et al.: J. Am. Chem. Soc., 135, 17135 (2013);<br></p>

<p>Applications 2,2-Diethylhexanoic Acid is a pollutant that is found in anaerobic environment of river sediments,<br>References Chau, H., et al.: Appl. Biochem. Biotechnol., 70, 853 (1998); McInerney, M., et al.: Appl. Env. Microbiol., 41, 1029 (1981)<br></p>

<p>Applications Butyl Benzoate has a fruity aroma an is commonly employed in food additives and flavorings. Butyl Benzoate is also a useful reagent in synthesis.<br>References Mkhonazi, B., et al.: Molecules., 25, 1040 (2020); Rottiers, H., et al.: Eur. Food Res. Technol., 245, 2459-2478 (2019)<br></p>

<p>Applications Substrate specificity of haloalkane dehalogenases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Koudelakova, T., et al.: Biochem. J., 435, 345 (2011),<br></p>

<p>Applications 2,2-Dimethyloctanoic Acid is used in biological studies as benzyl dimethyloctanoate metabolite of sewage bacteria.<br>References Millier, A., et al.: Bull. Environ. Contam. Toxicol., 28, 113 (1982);<br></p>

<p>Applications Dichloroacetonitrile is commonly used with gas chromatography-mass spectrometry instrument to evaluate and quantify the common halogenated disinfection by products using the headspace technique.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Montesinos, I., et al.: J. Chromatogr. A., 1310 113 (2013)<br></p>

<p>Applications Ergosine is an ergot alkaloid which are used in the treatment of vasoconstriction and as well as Parkinson’s disease. Also certain derivatives act as psychedelics mimicking lysergic acid.<br>References Martucci N. et al.: Cephal., 1, 151 (1983); Kehr, W. et al.: Eur. J. Phamracol., 41, 261 (1977);<br></p>

<p>Applications 1,3-Diethyl-2-thiourea (cas# 105-55-5) is a useful research chemical.<br></p>

<p>Applications 1,​1,​1,​2-​Tetrachloroethane is a chlorinated hydrocarbon and used as a solvent for cellulose, acetate, fat, waxes, greases, rubber, and sulfur. It is a contaminant in groundwater. 1,​1,​1,​2-​Tetrachloroethane can also induce heptotoxicity.Environmental contaminants; food contaminants.<br>References Lorah, M. M., and Olsen, L. D. Environ. Sci. Technol. 33, 227 (1999); Zheng, R. D., et al.: J Dig Dis. 13, 321 (2012)<br></p>

<p>Applications Pentadecanolide is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.<br>References Jan, S.U., et. al.: AFR. J. Pharm. Pharmacol., 6, 601 (2012)<br></p>

<p>Applications 1,2,3,4-Tetrachlorodibenzofuran-13C6 is the labelled version of 1,2,3,4-Tetrachlorodibenzofuran; a dioxin-like PCB impurity that is found in some Japanese agrochemical formulations.<br>References Masunaga, S., et al.: Chemosphere, 44, 873 (2001)<br></p>

<p>Applications Heptanoic-5,5,6,6,7,7,7-d7 Acid (CAS# 1219802-86-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications Phthalic Acid Bis(3,7-dimethyloctyl) Ester-d4 is the isotope labelled analog of Phthalic Acid Bis(3,7-dimethyloctyl) Ester (P384535); a diester derivative of Phthalic Acid (P384480) which can be used as a plasticizer for PVC-type compositions.<br>References Takeuchi, H., et al. Jpn. Kokai Tokkyo Koho. JP 2001002829 A 20010109. Jan 9, 2001<br></p>

<p>Applications Fucosterol is a steroid for proteomics research.<br></p>

<p>Applications isotope labelled Dibenzyl Phthalate is an plasticizer used in toys that was found to exhibit potential estrogen agonist/ antagonist properties.<br>References Zhang, Z.B., et al.: Toxicol. Lett., 207, 7 (2011); Mentlein, R., et al.: BIochem. Pharma., 38, 3126 (1989);<br></p>

<p>Applications 2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene (cas# 36431-72-8) is a useful research chemical.<br></p>

<p>Applications 2-Ethyl-alpha,alpha-d2-pyrazine-3,5,6-d3 (CAS# 1276197-45-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Nonadecane is a long chain saturated aliphatic hydrocarbon. Nonadecane is found in tar from coal and other forssil organic matter. Nonadecane is used as a fragrance agent in cosmetics and perfumes.<br>References Youtcheff, J.J. et al.: Org. Geochem., 5, 157 (1983): Etienne, J.J.: Riv. Ital. EPPOS, 15, 418 (1997);<br></p>

<p>Stability Hygroscopic<br>Applications (±)-Isomenthone is a constituent of some commercial essential oils with antimicrobial and antioxidant properties.<br>References Baratta, M., et al.: Flavour Frag. J., 13, 235 (1998); Iscan, G., et al.: J. Agric. Food Chem., 50, 3943 (2002)<br></p>

<p>Applications 5-Ethyl-6-hydroxyhexanoic Acid is an intermediate in the synthesis of metabolites of Bis(2-ethylhexyl) Phthalate (DEHP) (B433850).<br>References Kaulen, J., et al.: Tetrahedron., 38, 3299 (1982);<br></p>

<p>Applications Palmitoleic Acid is a polyunsaturated fatty acid which contributes to reduced protein oxidation in mammals.<br>References Mendez, L. et al.: Free Rad. Biol. Med., 55, 8 (2013);<br></p>

<p>Applications 1,2-Dichloropropane is a byproduct in the production of epichlorohydrin (E582310), an important industrial chemical, is a bifunctional alkylating agent with the potential to form DNA cross-links.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stratula, C., et al.: Revista. De. Chimie., 56, 677 (2005); Kaiser, E.W., et al.: J. Phy. Chem., 100, 9788 (1996);<br></p>

<p>Applications Vitamin D5 is used in the synthetic preparation of 1α-Hydroxyvitamin D5 a promising chemopreventive agent for breast cancer.<br>References Moriarty, R.M., Albinescu, D.: J. Org. Chem., 70, 7624 (2005)<br></p>

<p>Applications L-Ascorbic acid 2-phosphate (AA2P) is a long-acting ascorbic acid derivative that stimulates collagen expression and formation and is used in human cell culture.<br>References Kurata, S., et al.: J. Biol. Chem., 266, 9997 (1991); Svetec, N., et al.: J. Exp. Biol., 208, 891 (2004); Furue, M., et al.:Proc. Natl. Acad. Sci. USA, 105, 13409 (2008)<br></p>

<p>Applications 3-Methoxy-d3-benzaldehyde (CAS# 1219795-07-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Ethyl Benzoylformate is a general chemical reagent used in the preparation of diaminoethanediyl bismethylpyridinium salts for designing recyclable organocatalysts.<br>References Lisnyak, V. et al.: J. Org. Chem., 80, 8570 (2015);<br></p>

<p>Applications Tetracosanoic Acid is a chemical component of a dried mushroom powder exhibiting antioxidant properties. It is a long chain fatty acid present in peanut oil.<br>References Carneiro, A. et al: Food Chem., 138, 2168 (2013); Beare-Rogers, J. et al. Pure Appl. Chem., 74, 685 (2001);<br></p>

<p>Applications Diethyl DL-Malate is used as a reagent in the synthesis of dicarboxylic nitroxyalkylamides and nitroxyalkylimides as anti-ischemic agents.<br>References Fedorov, B.S., et al.: Russ. Chem. B+., 63, 1119 (2014)<br></p>

<p>Applications 1,2,3,4,6-Penta-O-acetyl-b-D-mannopyranose (cas# 4026-35-1) is a useful research chemical.<br></p>

<p>Applications 6α-Naloxol is a metabolite of Naloxone (N285000), a specific opioid antagonist. Narcotic antagonist.<br>References Chatterjie, N., et al.: J. Med. Chem., 18, 490 (1975); Bilsky, E., et al.: J. Pharmacol. Exp. Ther., 277, 484 (1996); Blokhina, E., et al.: Eur. J, Pharmacol., 406, 227 (2000); Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967); McNicholas, L.F., et al.: Drugs, 27, 81 (1984); Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985); Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)<br></p>

<p>Applications Monobenzyl Phthalate β-D-Glucuronide is glucuronide conjugates of Monobenzyl Phthalate (M524900) which is a metabolite of phtalate.<br>References Samandar, E., et al.: Environ. Res., 109, 641 (2009)<br></p>

<p>Stability Hygroscopic, Temperature Sensitive<br>Applications Most important of the provitamins A. Widely distributed in the plant and animal kingdom. In plants it occurs almost always together with chlorophyll. Vitamin A precursor. Ultraviolet screen.<br>References Karrer, et al.: Helv. Chim. Acta, 12, 1142 (1929), Fischli, M., et al.: Helv. Chim. Acta, 58, 1584 (1975), Desmet, J., et al.: Biochem. Biophys. Acta, 912, 211 (1987), Tan, C., et al.: Food Chem., 92, 661 (2005), Chu, B., et al.: J. Agric. Food Chem., 55, 6754 (2007),<br></p>

<p>Applications Alanine is an amino acid that occurs naturally in nature. It is a functional component in the alanine cycle which regulates the level of alanine aminotransferases which can be used as a diagnostic tool to predict type II diabetes.<br>References Naveed S. et al.: Diab., 53, 11 (2004);<br></p>

<p>Applications 2-Phenyl-d5-ethyl Isothiocyanate (CAS# 912627-98-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications Bis(2-ethoxyethyl) Phthalate-3,4,5,6-d4 (CAS# 1398066-12-0) is a useful isotopically labeled research compound.<br></p>

<p>Stability Volatile<br>Applications (Z)-1,2-Dichloroethene is a synthetic intermediate of solvents and chlorinated compounds. It is mainly used as a solvent for resins, fats, perfumes, dyes, paints, plastics thermosensitive, phenols, etc., also used to extract sensitive products cold to heat (caffeine, rubber, fragrant fat, etc). It is also used in some degreasing metals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mark, J.: Physical Properties of Polymer Handbook, Springer,? 2nd Edition, 1076 (2007)<br></p>