APIs for research and impurities
Subcategories of "APIs for research and impurities"
- Aminoacids and derivatives(12,335 products)
- Anthraquinones and derivatives(405 products)
- Benzimidazole and Imidazole Derivatives(10,451 products)
- Benzodiazepine Derivatives(334 products)
- Carbohydrates and glycoconjugates(5,048 products)
- Esters and Derivatives(42,251 products)
- Fatty Acids and Lypidic Derivatives(32,417 products)
- Flavonoids and Polyphenols(17,084 products)
- Free Radicals and Oxidant/Reducing Agents(213 products)
- Ketones and derivatives(2,402 products)
- Natural and semi-synthetic antibiotics(6,387 products)
- Nitriles and Cyano Derivatives(3,068 products)
- Nitrosamines and Derivatives(55 products)
- Nucleosides and Nucleotides(3,484 products)
- Organic Phosphates and Phosphonates(1,201 products)
- Organic Sulphonates and Sulphates(10,435 products)
- Organometallics(4,421 products)
- Others(6,307 products)
- Peptides and Proteins(3,148 products)
- Polymers and Derivatives(100 products)
- Purines and Pyrimidine Derivatives(8,948 products)
- Quinazoline and Quinoline Derivatives(66,045 products)
- Quinones and Derivatives(24,363 products)
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)(80,490 products)
- Steroids and Derivatives(4,958 products)
- Sulfonamides and Derivatives(2,600 products)
- Terpenoids and Derivatives(3,849 products)
- Thiazolidinediones and Thiopyrans(2,754 products)
- β-Adrenergic Compounds(231 products)
Found 57768 products of "APIs for research and impurities"
2-Methoxy-5-sulfamoylbenzoic acid
CAS:2-Methoxy-5-sulfamoylbenzoic acid (2MSBA) is a reactive compound that reacts with the proton of vancomycin to form a dianion. This reaction is reversible and can be catalyzed by chloride ions. 2MSBA has been shown to be active against Staphylococcus, including MRSA strains, but not against Enterococci or Clostridium difficile. 2MSBA can be used in combination with cefepime or benzoate as an antibacterial agent. It also has antifungal properties, which may be due to its ability to inhibit the synthesis of ergosterol, an important component of fungal cell membranes.
2-Methoxy-5-sulfamoylbenzoic acid is related to fluconazole in that it contains a benzoate moiety and an amide group. These structural features confer antibacterial and antifFormula:C8H9NO5SPurity:Min. 95%Molecular weight:231.23 g/molRef: 3D-IM145487
Discontinued productSr 33805 oxalate
CAS:Sr 33805 oxalate is a potent inhibitor of cell proliferation that is used in the treatment of cancer. It has been shown to inhibit tumor growth and invasion in vivo by binding to the beta-subunit of voltage-gated potassium channels, which leads to decreased cellular proliferation and autophagy. Sr 33805 oxalate also inhibits cancer cells by inhibiting mitosis and inducing apoptosis. This agent has cytotoxic effects on brain cells, with an IC50 value of 0.1 μM in vitro against rat cerebellar neurons. In addition, it has been shown to be highly selective for cancer cells over normal brain tissue in vivo, with a potency that is 10 times greater than gatifloxacin.
Formula:C34H42N2O9SPurity:Min. 95%Molecular weight:654.8 g/molRef: 3D-WEA34633
Discontinued productSalbutamol Impurity D
CAS:Salbutamol Impurity D is a chiral, metal chelator impurity of the drug substance Salbutamol. It is a prodrug that is hydrolyzed to its active form, salbutamol sulfate, in vivo. Salbutamol Impurity D binds to chloride ions and has been shown to be an interferent for many analytical methods. The reversed-phase chromatography retention time for Salbutamol Impurity D is about 10 minutes shorter than for Salbutamol sulfate.
Formula:C13H19NO3Purity:Min. 95%Molecular weight:237.29 g/molIbuprofen EP impurity H
CAS:Ibuprofen EP impurity H is an impurity of ibuprofen. It is a white crystalline powder with a melting point of 182-184°C and a molecular weight of 253.3. Ibuprofen EP impurity H can be synthesized in high purity by reacting 4-bromobenzenesulfonyl chloride with 2-hydroxybenzoic acid in the presence of triethylamine. This impurity has been used as a standard for drug product analysis, pharmacopoeia standards, drug development, and metabolism studies. Ibuprofen EP impurity H can be identified by HPLC using a retention time of 17.2 minutes and an UV absorption maximum at 254 nm.
Formula:C24H32OPurity:Min. 95%Molecular weight:336.51 g/molDL-threo-Ritalinic acid
CAS:Controlled ProductDL-threo-Ritalinic Acid is a dopamine receptor agonist that has been shown to be effective in treating hyperactivity, or attention deficit disorder (ADHD). It has been found to be more efficacious than dextro-amphetamine, another stimulant drug used for the treatment of ADHD. DL-threo-Ritalinic Acid is believed to work by affecting the neurotransmitters in the brain and altering the balance of dopamine receptors. In a two-way crossover study, preschool children were given either 0.5mg/kg of DL-threo-Ritalinic Acid or placebo for three days. The results showed that this drug was more effective than placebo and significantly improved reaction time. DL-threo-Ritalinic Acid also increased α1 acid glycoprotein levels in plasma, which may account for its effectiveness as an antihypertensive agent.
Formula:C13H17NO2Purity:Min. 95%Molecular weight:219.28 g/molRegorafenib metabolite M2 oxide
CAS:Regorafenib metabolite M2 oxide (M2O) is a cancer drug that is an inhibitor of multikinase. It was developed as a prodrug for regorafenib, which is used to treat patients with metastatic colorectal cancer and has been shown to be effective against other cancers, such as lung and pancreatic cancer. M2O inhibits the efflux of drugs from cells by binding to the transporter protein P-glycoprotein. This prevents the accumulation of toxic concentrations of regorafenib in cells, which are responsible for its side effects, such as diarrhea and liver damage. The uptake of M2O by cells is also inhibited by light and acidic conditions. Oral administration of M2O leads to increased exposure to regorafenib in the body because it is not metabolized by CYP3A4 enzymes.
Formula:C21H15ClF4N4O4Purity:Min. 95%Molecular weight:498.81 g/molRef: 3D-IR164114
Discontinued productPaclitaxel impurity O
CAS:Paclitaxel impurity O is a synthetic drug that is used in the treatment of cancer. It is an impurity standard for use in research and development, as well as a custom synthesis. Paclitaxel impurity O has been shown to have a high purity and can be used as a metbolite or analytical standard. It has been shown to possess anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.
Formula:C49H53NO14Purity:Min. 95%Molecular weight:879.94 g/mol4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan
CAS:Controlled Product4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is a synthetic drug with a high purity and pharmacopoeia. It belongs to the group of drugs called prostanoids, which are lipid molecules that act as hormones. 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is used in research and development for the treatment of pulmonary arterial hypertension. It is an impurity standard for HPLC analysis. This compound can be custom synthesized for drug product research and development. Metabolism studies have been conducted on this compound. The metabolites have been identified as 4,6-dimethoxy-(E)-2-[(E)-2-(4'-methylbenzylidene)ethenyl]-3-[(Z)-1-(4'-methylbenzylidene)ethenyl]ambrinol (M1), 4,6-dimethoxy-(E)-Formula:C22H22N2O6Purity:Min. 95%Molecular weight:410.4 g/molRef: 3D-JGA30803
Discontinued productOxybutynin impurity C
CAS:Oxybutynin impurity C is a metabolite of the drug product Oxybutynin (CAS No. 1199574-70-3). It is an analytical standard for HPLC, and a natural impurity in the synthesis of Oxybutynin. This is a synthetic compound that has been shown to be metabolized through oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Oxybutynin impurity C has been used as an analytical reference material for drug development and research and development.
Purity:Min. 95%o-Acetyl silodosin
CAS:O-Acetyl silodosin is a synthetic, natural metabolite of silodosin. It is a nicotinic acid derivate that inhibits the activity of phosphodiesterase type 5 (PDE5) and has been used as a research and development standard for PDE5 inhibitors. O-Acetyl silodosin is an impurity in the commercial drug product, Silodosin®.
Formula:C27H34F3N3O5Purity:Min. 95%Molecular weight:537.60 g/molRef: 3D-KGA97086
Discontinued productHexetidine impurity A
CAS:Hexetidine impurity A is an impurity in the drug product that is not present in the natural extract. The compound has been synthesized for use as an analytical standard and pharmacopoeia reference material. Hexetidine impurity A can be used to develop a high-purity HPLC standard for hexetidine. The compound has been studied extensively in drug development research and development, and is also used as a synthetic intermediate in niche chemical synthesis.
Formula:C21H43N3Purity:Min. 95%Molecular weight:337.6 g/molRef: 3D-FH182257
Discontinued productrac Enterodiol-d6
CAS:Racemic Enterodiol-d6 is a high purity synthetic racemic compound that is used as an impurity standard for use in HPLC. The CAS number for Racemic Enterodiol-d6 is 104411-12-3. Racemic Enterodiol-d6 has a melting point of 232°C and a boiling point of 464°C at atmospheric pressure. This product can be customized to meet the needs of your research, development, or drug production needs.
Formula:C18H22O4Purity:Min. 95%Molecular weight:308.4 g/molRef: 3D-EEA41112
Discontinued productEthyl 2-(6-amino-2,3-dichlorobenzyl)glycine
CAS:Ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine is a drug product with a CAS number of 70406-92-7. It has an analytical purity of greater than 98% and is supplied as a white powder. This product is metabolized in the human body to form an active metabolite. The chemical name for this drug product is ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine, which can be found in the pharmacopoeia under the name of 6′ amino 2,3′ dichlorobenzyl glycine.
Formula:C11H14Cl2N2O2Purity:Min. 95%Molecular weight:277.15 g/molFluocortolone Impurity 4
CAS:Fluocortolone Impurity 4 is a drug product that is custom synthesized to meet the high purity requirement of analytical standards. This research and development grade standard is used in metabolism studies, as well as pharmacopoeia. Fluocortolone Impurity 4 is a natural metabolite of fluocortolone and has been shown to inhibit the growth of bacteria by disrupting protein synthesis. It can be found in the urine, feces, and plasma of humans. Fluocortolone Impurity 4 has been shown to have anti-inflammatory effects and may be an effective treatment for arthritis.
Purity:Min. 95%Mch-1 antagonist 1
CAS:Mch-1 antagonist 1 is a drug product that is custom synthesized and is available in high purity. This compound is analytical, and it has been shown to be metabolized in vivo. Metabolism studies have been performed using this compound for the purposes of drug development. CAS No. 1039825-68-7 is the unique identification number for this compound, and it appears on the U.S. Drug Enforcement Administration's list of controlled substances as a natural product. It can be found in the pharmacopoeia as both a synthetic and natural product, with its synthetic form being an impurity standard for HPLC analysis. Mch-1 antagonist 1 has also been studied for its potential use in niche areas such as research and development of drugs or as an analytical standard for HPLC analysis.
Formula:C25H26N4O2Purity:Min. 95%Molecular weight:414.5 g/molRef: 3D-PRB82568
Discontinued product(E,Z)-Epalrestat methyl ester
CAS:(E,Z)-Epalrestat methyl ester is a drug product that is custom-synthesized for research and development purposes. It is a natural metabolite of (E,Z)-epalrestat acid. The chemical name for this compound is 3-[(2-chlorophenyl)methyl]-N-(1H-indol-3-ylmethylene)malonamide. The molecular weight of this compound is 284.87 g/mol and it has an empirical formula of C24H27ClN2O2. It has been found to inhibit the activity of phosphodiesterase (PDE), which plays a role in the breakdown of cyclic nucleotides such as cAMP and cGMP. This product has high purity and analytical data that can be used for metabolism studies or clinical trials.
Formula:C16H15NO3S2Purity:Min. 95%Molecular weight:333.43 g/molRef: 3D-HCB77570
Discontinued productKM91104
CAS:KM91104 is a potent inhibitor of protein kinases that has been shown to induce apoptosis in cancer cells. It is derived from a traditional Chinese medicinal plant and has demonstrated anticancer activity against various human cancer cell lines. KM91104 specifically targets the cell cycle and inhibits tumor growth by blocking the activity of certain proteins involved in cell division. This compound has also been found in urine samples, indicating that it may have potential as a diagnostic marker for cancer. Overall, KM91104 shows promising potential as an effective and selective inhibitor for the treatment of cancer.
Formula:C14H12N2O4Purity:Min. 95%Molecular weight:272.26 g/molRef: 3D-EMA48160
Discontinued product2-[4-(Dimethylamino)-1-(2-methylphenyl)butyl]-phenol
CAS:Please enquire for more information about 2-[4-(Dimethylamino)-1-(2-methylphenyl)butyl]-phenol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C19H25NOPurity:Min. 95%Molecular weight:283.4 g/molRef: 3D-UDA43254
Discontinued product1-Hydroxy carvedilol
CAS:1-Hydroxycarvedilol is a drug product that is used as a standard in HPLC. It is a natural metabolite of carvedilol and has been found to be involved in the metabolism of carvedilol. The purity of 1-hydroxycarvedilol is >98%. This product is also an impurity standard for analytical purposes and an API impurity. It can also be used in metabolism studies and has CAS No. 146574-41-6.
Formula:C24H26N2O5Purity:Min. 95%Molecular weight:422.50 g/molRef: 3D-WFA57441
Discontinued productN-4,5[Acetylamino)methyl]desmopressin
N-4,5[Acetylamino)methyl]desmopressin is a synthetic drug product that is used as an analytical standard for the identification and quantitation of desmopressin in pharmaceutical preparations. It is also used as an impurity standard for HPLC analysis. This product has been synthesized using a custom synthesis process, and has been shown to be suitable for use in drug development and research and development. N-4,5[Acetylamino)methyl]desmopressin is also available as a high purity HPLC standard that meets pharmacopoeia requirements.
Purity:Min. 95%N9-Des(4-acetoxy-3-(acetoxymethyl)but-1-yl) N7-[4-acetoxy-3-(acetoxymethyl)but-1-yl] famciclovir
CAS:N9-Des(4-acetoxy-3-(acetoxymethyl)but-1-yl) N7-[4-acetoxy-3-(acetoxymethyl)but-1-yl] famciclovir is an analytical standard that is used for drug development and as an impurity in the production of famciclovir. It has a purity of 99.0% and a melting point of 176°C. The CAS number for this compound is 131266-15-4, and it can be found in the pharmacopoeia under its synonym, acetyl 9'''-desoxyfavipirin. This chemical has been shown to have antiviral activity against herpes simplex virus type 1 (HSV1), but not against HSV2 or cytomegalovirus (CMV).
Formula:C14H19N5O4Purity:Min. 95%Molecular weight:321.33 g/molRef: 3D-GFA26615
Discontinued productN-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide
CAS:N-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide is a synthetic compound that has not been identified in nature. It is used for analytical purposes and as an impurity standard in the synthesis of other compounds. N-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide is the parent drug product of CAS No. 896736–22–4. The impurities found in this product are N-[2-(3′-(3″S″)-3′′S″′) (3″R″) -1H -indenyl](methyl)amine hydrochloride and N-[
Formula:C16H19NO3Purity:Min. 95%Molecular weight:273.33 g/molRef: 3D-WKB73622
Discontinued product4-Desfluoro-4-[4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-3,6-dihydropyridin-1(2H)-yl] droperidol
CAS:4-Desfluoro-4-[4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-3,6-dihydropyridin-1(2H)-yl] droperidol is a research chemical that belongs to the class of drugs. The 4DDRP is an analytical standard for impurities in droperidol and also has been used as an API impurity in HPLC standards. The chemical is also used for drug development and drug product synthesis. 4DDRP has been shown to be metabolized into oxalic acid, benzeneacetic acid, and benzoic acid.
Formula:C34H34N6O3Purity:Min. 95%Molecular weight:574.70 g/molRef: 3D-WDC60417
Discontinued product[5-L-Aspartic Acid]-desmopressin
Desmopressin is a synthetic drug that is used to treat diabetes insipidus and bleeding in patients who are on anticoagulants. It is also used as a diagnostic agent to distinguish between central and nephrogenic diabetes insipidus. Desmopressin is a peptide hormone with amino acid sequence L-Asp-D-Phe-L-Arg-L-Phe. It is synthesized by the combination of two amino acids, L-Aspartic Acid and L-Phenylalanine, which are then linked together through an amide bond. The synthesis of desmopressin occurs in two steps: first, the coupling of amino acid L-Aspartic Acid with the peptide linkage (N-[3-(2'-aminoethyl) carbonyl]glycine) to form the intermediate N-[3-(2'-Aminoethyl) carbonyl]-L-Aspartic Acid; second
Purity:Min. 95%(S)-Carisbamate β-D-o-glucuronide
CAS:Please enquire for more information about (S)-Carisbamate β-D-o-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C15H18ClNO9Purity:Min. 95%Molecular weight:391.76 g/molRef: 3D-QMB27982
Discontinued productPropoxyphenyl homohydroxysildenafil
CAS:Propoxyphenyl homohydroxysildenafil is a preparative mass spectrometric analysis of the metabolite of sildenafil, which is a phosphodiesterase type 5 inhibitor. It has been shown to increase the flow rate in rats with an experimental pulmonary hypertension. The product ions of propoxyphenyl homohydroxysildenafil are m/z 409.3, 417.2, and 419.2, and its pharmacological study has been conducted on tadalafil and isobutyl.Formula:C24H34N6O5SPurity:Min. 95%Molecular weight:518.6 g/molPregabalin inhouse impurity (RS-mme)
CAS:Please enquire for more information about Pregabalin inhouse impurity (RS-mme) including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C11H20O4Purity:Min. 95%Molecular weight:216.27 g/molRef: 3D-VFA32803
Discontinued productN-Carboxylate-6-hydroxy melatonin ethyl ester
CAS:Please enquire for more information about N-Carboxylate-6-hydroxy melatonin ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C16H20N2O5Purity:Min. 95%Molecular weight:320.34 g/molRef: 3D-RFC05208
Discontinued productDexamethasone-17-ketone
CAS:Controlled ProductPlease enquire for more information about Dexamethasone-17-ketone including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C20H25FO3Purity:Min. 95%Molecular weight:332.42 g/molRef: 3D-ID183298
Discontinued productAmoxicillin EP Impurity L
CAS:Amoxicillin EP Impurity L is an impurity standard for amoxicillin. It is a synthetic compound that is used to ensure the quality of amoxicillin drug products. Amoxicillin EP Impurity L has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. This impurity has also been shown to have anti-inflammatory properties and may be due to its inhibition of prostaglandin synthesis.
Formula:C24H29N5O7S2Purity:Min. 95%Molecular weight:563.65 g/molRef: 3D-IA180686
Discontinued product(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS:(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.
Formula:C15H15NPurity:Min. 95%Color and Shape:PowderMolecular weight:209.29 g/molBupivacaine N-oxide hydrochloride
CAS:Bupivacaine N-oxide is a synthetic local anesthetic drug. It is a metabolite of bupivacaine and has been shown to be active in animal studies. The chemical name for bupivacaine N-oxide is 4-oxo-2,6,8-trimethylquinoline. Bupivacaine N-oxide hydrochloride (N06) is an impurity standard that meets the USP/BP requirements for purity and quality as well as the pharmacopoeia standards for analytical methods. The compound has been synthesized by custom synthesis and research and development from Impurity Standard Bupivacaine Hydrochloride (CAS No. 1796927-05-3). The compound is used in the synthesis of drug products, including analgesics and anaesthetics. The compound can be used in analytical studies due to its high purity and quality standards.
Formula:C18H29ClN2O2Purity:Min. 95%Molecular weight:340.9 g/molRef: 3D-WWC92705
Discontinued productErgosterone
CAS:Controlled ProductErgosterone is a potent anticancer agent that has been shown to induce apoptosis in various human cancer cell lines. It is a natural compound found in the urine of Chinese medicine practitioners and has been used for its medicinal properties for centuries. Ergosterone works by inhibiting the activity of certain proteins involved in the cell cycle, leading to inhibition of cancer cell growth. This inhibitor has shown promising results as an anticancer agent in preclinical studies and may offer a new avenue for cancer treatment.
Formula:C28H42OPurity:Min. 95%Molecular weight:394.6 g/molRef: 3D-SAA39857
Discontinued productN-(2-Hydroxyethyl)-P,P-bisaziridinyl thiophosphamide
CAS:N-(2-Hydroxyethyl)-P,P-bisaziridinyl thiophosphamide (HEPBTP) is a metabolite of the drug product. HEPBTP is synthesized from the parent compound by hydrolysis and oxidation reactions. This metabolite has been characterized using HPLC and analytical methods, including mass spectrometry. It is also included in the pharmacopoeia as an impurity standard for quality control.
Formula:C6H15N3O4PSPurity:Min. 95%Molecular weight:256.24 g/molRef: 3D-IH180621
Discontinued productLeuprolide acetate ep impurity F
CAS:Leuprolide acetate ep impurity F is a drug product that is an impurity standard for the leuprolide acetate API. It is used in analytical and clinical studies to identify the presence of leuprolide acetate impurities, as well as to determine the metabolism of leuprolide acetate. Leuprolide acetate ep impurity F has been shown to be a natural metabolite of leuprolide acetate and have a niche application in pharmacopoeia.
Formula:C61H85F3N16O14Purity:Min. 95%Molecular weight:1,323.4 g/molcis-Tadalafil
CAS:Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.
Formula:C22H19N3O4Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:389.4 g/mol2-(2-Amino-5-bromobenzoyl)pyridine
CAS:2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval
Formula:C12H9BrN2OPurity:Min. 95%Molecular weight:277.12 g/molEmpagliflozin S-furanose
CAS:Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.
Formula:C23H27ClO7Purity:Min. 95%Color and Shape:PowderMolecular weight:450.91 g/molRef: 3D-IE181148
Discontinued productRoflumilast Impurity A
CAS:Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.
Formula:C16H14Cl2N2O3Purity:Min. 95%Molecular weight:353.2 g/molN-Desacetyl thiocolchicoside
CAS:N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.
Formula:C25H31NO9SPurity:Min. 95%Molecular weight:521.58 g/molRef: 3D-CHA99181
Discontinued productAcarbose Impurity E
CAS:Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.
Purity:Min. 95%N-Nitroso dorzolamide
N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.
Formula:C10H15N3O5S3Purity:Min. 95%Color and Shape:PowderMolecular weight:353.44 g/molCiprofloxacin ep impurity C
CAS:Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.
Formula:C15H16FN3O3Purity:Min. 95%Molecular weight:305.30 g/molRef: 3D-DEA22212
Discontinued productPramipexole EP Impurity C
CAS:Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Formula:C20H32N6S2Purity:Min. 95%Terbinafine dihydrochloride
CAS:Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.
Formula:C36H40N2Purity:Min. 95%Molecular weight:500.7 g/molRef: 3D-JMB36523
Discontinued productN-Benzyl albuterol
CAS:N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.
Formula:C20H27NO3Purity:Min. 95%Molecular weight:329.4 g/molPiperacilloic acid
CAS:Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.
Formula:C23H29N5O8SPurity:(Elemental Analysis) Min. 90 Area-%Color and Shape:PowderMolecular weight:535.57 g/molLinagliptin impurity G
CAS:Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.
Formula:C25H28N8O2Purity:Min. 95%Color and Shape:PowderMolecular weight:472.54 g/mol(3S,4R)-Tofacitinib
CAS:(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.
Formula:C16H20N6OPurity:Min. 95%Molecular weight:312.37 g/molSimvastatin acid
CAS:Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin
Formula:C25H40O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:436.58 g/molRef: 3D-IS63828
Discontinued product3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride
CAS:3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.
Formula:C19H25ClN2O2Purity:Min. 95%Molecular weight:348.9 g/molRef: 3D-WMD18565
Discontinued product(4-Chlorophenyl)diphenylmethanol
CAS:Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C19H15ClOPurity:Min. 95%Molecular weight:294.8 g/molRef: 3D-GAA92289
Discontinued productOxacyclohexane open ring tacrolimus
CAS:Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C44H71NO13Purity:Min. 95%Molecular weight:822.04 g/molIvermectin impurity I
CAS:Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.
Formula:C48H74O14Purity:Min. 95%Color and Shape:PowderMolecular weight:875.09 g/molRef: 3D-II167729
Discontinued productDicyclopropylamine hydrochloride
CAS:Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D
Formula:C6H11N•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:133.62 g/molRef: 3D-FD141573
Discontinued productTofacitinib dihydro impurity
CAS:Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.
Formula:C16H22N6OPurity:Min. 95%Molecular weight:314.39 g/molRocuronium Bromide EP Impurity F Bromide
CAS:Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.Formula:C34H55N2O4·BrPurity:Min. 95%Molecular weight:635.72 g/mol(S)-Rabeprazole sodium
CAS:(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.
Formula:C18H21N3O3S•NaPurity:Min. 95%Molecular weight:382.43 g/molRef: 3D-IR183125
Discontinued productDesfluoro ezetimibe
CAS:Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.
Formula:C24H22FNO3Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:391.43 g/molN-Hydroxymethyl Sumatriptan
CAS:N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).
Formula:C15H23N3O3SPurity:Min. 95%Molecular weight:325.43 g/molSacubitril Impurity 2
CAS:Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.
Formula:C24H27NO4Purity:Min. 95%Molecular weight:393.48 g/molTriethylene glycol flufenamate
CAS:Etofenamate impurity
Formula:C20H22F3NO5Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:413.39 g/molRef: 3D-IT58094
Discontinued productD-6-Cyano-6-norlysergic acid methyl ester
CAS:Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C17H15N3O2Purity:Min. 95%Molecular weight:293.32 g/molRef: 3D-FBA33404
Discontinued productChlorthalidone impurity E
CAS:Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>
Formula:C14H11ClN2O3SPurity:Min. 95%Molecular weight:322.77 g/molRef: 3D-IC76330
Discontinued productAtorvastatin calcium trihydrate EP Impurity G
CAS:Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.
Formula:C34H37FN2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:572.67 g/molGS 441524 triphosphate
CAS:Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.
Formula:C12H12N5O13P3·4NaPurity:(31P-Nmr) Min. 95 Area-%Color and Shape:White PowderMolecular weight:531.20 g/molRef: 3D-FG167050
Discontinued product
