APIs for research and impurities
Active Pharmaceutical Ingredients (APIs) are the substances in drugs responsible for their therapeutic effects. In this section, you will find a wide variety of APIs intended for research use. These compounds are essential for the development, testing, and validation of new pharmaceutical formulations. CymitQuimica offers high-quality APIs to support research in drug discovery and development.
Subcategories of "APIs for research and impurities"
- Aminoacids and derivatives(12,441 products)
- Anthraquinones and derivatives(407 products)
- Benzimidazole and Imidazole Derivatives(10,465 products)
- Benzodiazepine Derivatives(335 products)
- Carbohydrates and glycoconjugates(5,388 products)
- Esters and Derivatives(42,307 products)
- Fatty Acids and Lypidic Derivatives(32,488 products)
- Flavonoids and Polyphenols(17,101 products)
- Free Radicals and Oxidant/Reducing Agents(214 products)
- Ketones and derivatives(2,692 products)
- Natural and semi-synthetic antibiotics(6,411 products)
- Nitriles and Cyano Derivatives(3,070 products)
- Nitrosamines and Derivatives(55 products)
- Nucleosides and Nucleotides(3,492 products)
- Organic Phosphates and Phosphonates(1,205 products)
- Organic Sulphonates and Sulphates(10,452 products)
- Organometallics(4,425 products)
- Others(6,340 products)
- Peptides and Proteins(3,163 products)
- Polymers and Derivatives(100 products)
- Purines and Pyrimidine Derivatives(8,975 products)
- Quinazoline and Quinoline Derivatives(66,221 products)
- Quinones and Derivatives(24,379 products)
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)(92,967 products)
- Steroids and Derivatives(4,987 products)
- Sulfonamides and Derivatives(2,607 products)
- Terpenoids and Derivatives(3,871 products)
- Thiazolidinediones and Thiopyrans(2,755 products)
- β-Adrenergic Compounds(232 products)
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Found 66884 products of "APIs for research and impurities"
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2,5-Pyrazinedipropionic acid
CAS:2,5-Pyrazinedipropionic acid is a pyrazine derivative with two carboxylic acid groups. It has been shown to be effective in the stabilization of bladder tissue and as a treatment method for bladder cancer. 2,5-Pyrazinedipropionic acid can also be used in the diagnosis of cutaneous melanoma and mesoporous silica nanoparticles that are used in cancer detection. The compound has been found to have a high melting point and water absorption capacity, which makes it suitable for use as an aminolevulinic acid precursor for photodynamic therapy. The compound also has vibrational spectral characteristics that make it suitable for nucleophilic attack on DNA
Formula:C10H12N2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:224.21 g/mol5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole
CAS:5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole is a natural product. It is an impurity in the drug development process and may be present as an analytical marker for impurities. 5-Methoxy-2-[(3,5-dimethylpyridinium)methyl]sulfinyl]-1Hbenzimidazole is used as a pharmacopoeia standard and can be synthesized on request.Formula:C16H17N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:315.39 g/mol5-(2-Ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS:Sildenafil is a selective PDE-5 inhibitor that is used in the treatment of erectile dysfunction. It has been shown to have anticancer activity in vitro and in vivo. Sildenafil inhibits the activity of cyclic guanosine monophosphate (cGMP) phosphodiesterase type 5 (PDE-5), which is found in the corpus cavernosum of the penis and inhibits cGMP degradation, leading to vasodilation and increased blood flow. Sildenafil has been shown to inhibit cancer cell proliferation by blocking the synthesis of both DNA and protein, as well as inhibiting the expression of genes encoding for anti-apoptotic proteins. Sildenafil binds to PDE-5 with high affinity, but does not bind to other PDEs or ion channels at therapeutic concentrations.Formula:C17H20N4O2Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:312.37 g/mol4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine
CAS:4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine is an impurity standard of the drug product. It is a high purity synthetic compound with a niche in pharmacopoeia and drug development. 4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine has been shown to be a metabolite of the natural product.Formula:C6H5IN4Purity:Min. 97 Area-%Color and Shape:PowderMolecular weight:260.04 g/molHydrocortisone dimer impurity 4
Hydrocortisone dimer impurity 4 is an impurity found in the drug product Hydrocortisone. It is a natural, API impurity, CAS No. 5949-44-8, and has been synthesized for use as an analytical standard. The substance's Metabolism studies were conducted using rats and mice, and it was found to be metabolized mainly by hydrolysis with glucuronidases or esterases. It also has a high purity of >99%.Purity:Min. 95%Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside
CAS:Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside is a synthetic impurity standard for the drug product. It has been used in studies on metabolism and as an analytical reference material. Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside is also available as a custom synthesis at high purity.Formula:C22H24O6Purity:Min. 95%Color and Shape:White powder.Molecular weight:384.42 g/molCalcipotriol EP Impurity B
Calcipotriol EP Impurity B is a drug product that is an impurity in Calcipotriol EP. It is produced during the synthesis of calcipotriol and may be present in the natural product. It has been shown to have anti-inflammatory properties, and can be used as a research tool to study calcipotriol metabolism.Formula:C27H40O3Purity:Min. 95%Molecular weight:412.6 g/molAcetylenedicarboxylic acid methyl ester
CAS:Acetylenedicarboxylic acid methyl ester (ADME) is a potent inhibitor of kinases that play a crucial role in cancer cell growth and apoptosis. It has been shown to exhibit anticancer activity against various tumor cell lines, including Chinese hamster ovary cells and human bladder carcinoma cells. ADME has also been found in urine samples from healthy individuals, indicating its presence in the human body. This compound specifically targets D-xylose kinases, which are overexpressed in certain cancer cells, leading to their growth inhibition and apoptosis induction. As an inhibitor of these kinases, ADME has potential as a therapeutic agent for the treatment of cancer.Formula:C5H4O4Purity:Min. 95%Molecular weight:128.08 g/molLinear Semaglutide
Linear semaglutide, or simply L-Sema, is the semaglutide compound without the lipid side chain modification. It is essentially a linear version of the peptide.Formula:C152H230N42O47Molecular weight:3,397.76 g/mol5-Hydroxy duloxetine
CAS:5-Hydroxy duloxetine (5HD) is a drug product that is synthesized by Custom Synthesis. It has high purity and analytical specifications, and can be used for metabolism studies, natural product development, pharmacopoeia, and research and development. 5HD also has a CAS number of 741693-77-6. This product is synthetically produced with impurity standards. The molecular weight of 5HD is 236.3 g/mol with an impurity level of less than 1%. 5HD can be used in the following applications: HPLC standard, HPLC calibration standard, Impurity standard for LCMS, Impurity standard for GCMS.
Formula:C18H19NO2SPurity:Min. 95%Color and Shape:PowderMolecular weight:313.40 g/molDoxorubicin impurity
CAS:Doxorubicin is an organic compound that belongs to the class of polycyclic aromatic hydrocarbons. It is used as a cancer therapy, primarily in the treatment of breast cancer. The chemical sensing of impurities in doxorubicin can be done using phase transfer methods. The quantification of these impurities can be done using high-performance liquid chromatography (HPLC) or gas chromatography (GC).Formula:C26H27NO11Purity:Min. 90 Area-%Color and Shape:Red PowderMolecular weight:529.49 g/molAfatinib Impurity 2
CAS:Afatinib Impurity 2 is a synthetic API impurity that is used as an HPLC standard in the pharmaceutical industry. It is also a metabolite of afatinib, which is used as a drug product. This impurity has niche applications in drug development and research and development. Afatinib Impurity 2 has been synthesized from natural sources and can be custom-synthesized to meet customer needs.Purity:Min. 95%Ceftazidime impurity B
CAS:Ceftazidime impurity B is a ceftazidime impurity that is found in the drug Ceftazidime. Ceftazidime is an antibiotic that belongs to the group of cephalosporin antibiotics and inhibits bacterial growth by inhibiting cell wall synthesis. Ceftazidime impurity B has been shown to be toxic to gram-positive bacteria, such as Enterococcus faecium and Staphylococcus aureus, but not to gram-negative bacteria, such as Escherichia coli. In addition, it has been shown to have no effect on the IL-2 receptor of T cells or the binding of penicillin-binding protein. It has also been shown to be safe for injection into mice and rats in toxicity studies.Formula:C22H22N6O7S2Purity:Min. 95%Molecular weight:546.58 g/molAtorvastatin diepoxide
CAS:Atorvastatin diepoxide is an analytical standard for the drug atorvastatin that is used in the development of pharmaceuticals. It is synthesized by reacting atorvastatin with epichlorohydrin, which produces a diepoxide derivative. This synthetic molecule can be used as an impurity standard for HPLC analysis. The CAS number for atorvastatin diepoxide is 887470-43-1.
Formula:C33H35FN2O7Purity:Min. 95%Molecular weight:509.64 g/mol2,4-Dicyano-3-(3,4-dihydroxy-5-nitrophenyl)-N1,N1,N5,N5-tetraethylpentanediamide
2,4-Dicyano-3-(3,4-dihydroxy-5-nitrophenyl)-N1,N1,N5,N5-tetraethylpentanediamide is a white crystalline solid that is used as an analytical reference standard in HPLC. It is used for the determination of purity and impurities in pharmaceuticals and drug products. This compound can be custom synthesized or obtained from natural sources. It can be found in the USP Drug Impurity Standards and the European Pharmacopoeia.Formula:C21H27N5O6Purity:Min. 95%Molecular weight:445.47 g/molN-Methyl-3-(4-naphthol)-3-(2-thienyl) propanamine hydrochloride
CAS:N-Methyl-3-(4-naphthol)-3-(2-thienyl) propanamine hydrochloride is a custom synthesis that has been shown to be a metabolite of naphthalene. It has been used as an impurity standard for N-methyl-3-(4-naphthol)-2-[(5-nitrofuran-2-yl)methyl] propanamine and in metabolism studies.Formula:C18H19NOS•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:333.88 g/mol3-(3-(Trifluoromethl)phenyl-N-(R)-1-(naphthalen-1-yl)ethyl)prop-2-en-1-amine hydrochloride
CAS:3-(3-(Trifluoromethl)phenyl-N-(R)-1-(naphthalen-1-yl)ethyl)prop-2-en-1-amine is a synthetic compound, which is not found in nature. It is an API impurity and a metabolite of the drug product. It can be synthesized in high purity and with a custom synthesis. 3-(3-(Trifluoromethl)phenyl-N-(R)-1-(naphthalen-1-yl)ethyl)prop-2-en-1-amine has been found to be involved in metabolism studies and research and development, as well as analytical purposes. This compound can also serve as an impurity standard for HPLC analysis.Formula:C22H20F3N•HClPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:391.86 g/mol4-(Aminomethyl)-1-cyclohexene-1-carboxylic acid
CAS:4-(Aminomethyl)-1-cyclohexene-1-carboxylic acid is an antifibrinolytic agent that can be used to control bleeding. It is a carboxymethyl cellulose with a menthol flavour and it stabilizes the hemostatic effect of tranexamic acid. 4-(Aminomethyl)-1-cyclohexene-1-carboxylic acid has been shown to be effective in controlling bleeding in patients with disorders such as hemophilia and von Willebrand disease. The drug is stable in acidic compositions, making it useful for dental applications as well.Formula:C8H13NO2Purity:Min. 95%Color and Shape:White PowderMolecular weight:155.19 g/molN-[4-Amido-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)-(R,S)-sulphinyl]-(R,S)-2-hydroxy-2-methylpropanamide
CAS:N-[4-Amino-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)-(R,S)-sulphinyl]- (R,S)-2-hydroxy-2-methylpropanamide is a sulfoxide that was designed to inhibit cancer cell proliferation. It has been shown to have anticancer activity in different models. The synthesis of this compound begins with the chlorination of 4-aminophenol, which produces 4-(chloromethyl)benzenesulfonyl chloride. This is then reacted with (R,S)-α-(4-Fluorophenyl)acetic acid and the resulting product is purified by column chromatography to give N-[4-(chloromethyl)phenyl]-3-[(4-fluorophenyl)(R,S)-sulphinyl]propaneamide. The final step in the synthesis is achieved by reacting the amideFormula:C18H14F4N2O3SPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:414.37 g/mol3-Amino-4-carbamoylpyrazole hemisulfate
CAS:3-Amino-4-carbamoylpyrazole hemisulfate is a white to yellowish crystalline powder that is soluble in water and methanol. It is a condensation product of allopurinol and ethyl orthoformate with a molecular weight of 312.4. 3-Amino-4-carbamoylpyrazole hemisulfate can be used as an anti-inflammatory agent, but it has not been approved for medical use in the United States.Formula:C4H6N4OH2O4SPurity:Min. 95%Color and Shape:White PowderMolecular weight:175.16 g/mol
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