APIs for research and impurities
Subcategories of "APIs for research and impurities"
- Aminoacids and derivatives(12,348 products)
- Anthraquinones and derivatives(405 products)
- Benzimidazole and Imidazole Derivatives(10,463 products)
- Benzodiazepine Derivatives(335 products)
- Carbohydrates and glycoconjugates(5,048 products)
- Esters and Derivatives(42,305 products)
- Fatty Acids and Lypidic Derivatives(32,454 products)
- Flavonoids and Polyphenols(17,098 products)
- Free Radicals and Oxidant/Reducing Agents(214 products)
- Ketones and derivatives(2,402 products)
- Natural and semi-synthetic antibiotics(6,398 products)
- Nitriles and Cyano Derivatives(3,070 products)
- Nitrosamines and Derivatives(55 products)
- Nucleosides and Nucleotides(3,486 products)
- Organic Phosphates and Phosphonates(1,202 products)
- Organic Sulphonates and Sulphates(10,447 products)
- Organometallics(4,424 products)
- Others(6,322 products)
- Peptides and Proteins(3,151 products)
- Polymers and Derivatives(100 products)
- Purines and Pyrimidine Derivatives(8,957 products)
- Quinazoline and Quinoline Derivatives(66,131 products)
- Quinones and Derivatives(24,376 products)
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)(80,360 products)
- Steroids and Derivatives(4,975 products)
- Sulfonamides and Derivatives(2,606 products)
- Terpenoids and Derivatives(3,858 products)
- Thiazolidinediones and Thiopyrans(2,755 products)
- β-Adrenergic Compounds(231 products)
Found 57677 products of "APIs for research and impurities"
Pravastatin diol lactone
CAS:Pravastatin diol lactone is a lipase inhibitor that prevents the hydrolysis of triglycerides in the intestines. It also inhibits the synthesis of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Pravastatin diol lactone has been shown to be effective in reducing serum cholesterol levels in animal models and inhibiting esterification of cholesterol by preventing the conversion of HMG-CoA to mevalonic acid, which is an important step in the synthesis of cholesterol. Pravastatin diol lactone is a polyketide that was discovered from a fungus and chemically altered to produce this drug.
Formula:C18H26O5Purity:Min. 95%Molecular weight:322.4 g/molRef: 3D-JGA34593
Discontinued productOxybutynin EP impurity A
CAS:Oxybutynin EP impurity A is a metabolite of oxybutynin, an antispasmodic drug. It has been shown to have immunomodulatory effects in a rat model of adjuvant arthritis. Oxybutynin EP impurity A is the major metabolite of oxybutynin and has been shown to be pharmacologically active in humans.
Purity:Min. 95%Ref: 3D-FO171019
Discontinued productN-Formyl leurosine
CAS:N-Formyl leurosine is an inhibitor of fatty acid synthesis. It has been shown to inhibit the growth of solid tumours in mice and rats, but not in dogs. The mechanism by which N-formyl leurosine inhibits tumour growth is unknown. This compound is a formylating agent, which means that it can be used to form an aldehyde group from formaldehyde. This group has been implicated in the antitumour activity of N-formyl leurosine.
Formula:C46H54N4O10Purity:Min. 95%Molecular weight:822.94 g/molRef: 3D-IF23552
Discontinued productTofacitinib impurity 69
CAS:Please enquire for more information about Tofacitinib impurity 69 including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C15H23N5Purity:Min. 95%Molecular weight:273.38 g/molRef: 3D-IMD51970
Discontinued productN-Desmethyl trimeprazine
CAS:N-Desmethyl trimeprazine is a synthetic compound, which is an impurity of the drug product. It is not active and does not possess any biological activity. It is a metabolite of the parent drug, Trimeprazine. N-Desmethyl trimeprazine has been studied for its pharmacological properties and metabolism in the body, but no conclusive results have been found. The chemical structure and purity of N-Desmethyl trimeprazine are not listed in the USP or BP. This compound can be custom synthesized on request.
Formula:C17H20N2SPurity:Min. 95%Molecular weight:284.40 g/molRef: 3D-XAA73204
Discontinued product(Z)-Fluvoxamine - EP
CAS:Controlled Product(Z)-Fluvoxamine-EP is a drug product that is used as an analytical standard. It is a synthetic metabolite of fluvoxamine, which is a drug used for the treatment of depression. The synthesis of (Z)-fluvoxamine-EP is based on the asymmetric synthesis of fluvoxamine and the use of chiral chromatography to purify the product. This synthetic process allows for the production of high-purity (Z)-fluvoxamine-EP with a purity greater than 99%.
Formula:C15H21F3N2O2Purity:Min. 95%Molecular weight:318.33 g/molRef: 3D-IF23523
Discontinued productRocuronium EP Impurity G
CAS:Rocuronium EP Impurity G is a drug product that contains an impurity of Rocuronium EP. It is a synthetic, high purity HPLC standard with a purity greater than 99.5% and a CAS number of 119302-20-4. This compound has been researched for use in the development of drugs to treat conditions such as pain, anxiety, and depression. Rocuronium EP Impurity G is a metabolite that has been found in human urine after administration of rocuronium bromide. The metabolism of this substance has not been fully elucidated yet but it may be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid.
Formula:C27H46N2O3Purity:Min. 95%Molecular weight:446.67 g/mol1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid
CAS:1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid (1bRT) is an amide that inhibits the growth of viruses by inhibiting the viral enzyme thiosemicarbazide. It has been shown to be active against specific viruses such as HIV and retroviruses. 1bRT is used to treat lung diseases caused by viruses, including bronchiolitis, pneumonia, and pulmonary fibrosis. It also has antibacterial properties. Studies have shown that 1bRT reduces the number of bacteria in body fluids and helps to prevent respiratory infections and other bacterial infections in people with weakened immune systems due to AIDS or cancer treatment.
Formula:C8H11N3O5Purity:Min. 95%Molecular weight:229.19 g/molRef: 3D-IR138822
Discontinued productBendamustine isopropyl ester
CAS:Bendamustine isopropyl ester is a synthetic, high purity drug product. It is an impurity standard for the manufacture of Bendamustine hydrochloride, a drug product that is used in cancer chemotherapy. Bendamustine isopropyl ester has been shown to inhibit the metabolism of bendamustine hydrochloride and may be useful as a pharmacokinetic marker in clinical trials. Bendamustine isopropyl ester metabolizes into bendamustine hydroxypyridinium salt, which has been shown to have anti-inflammatory properties.
Formula:C19H27Cl2N3O2Purity:Min. 95%Molecular weight:400.30 g/molRef: 3D-NCC02025
Discontinued product17-o-(Acetyl-d3)-6-methylprednisolone
CAS:Controlled Product17-o-(Acetyl-d3)-6-methylprednisolone is a drug product that belongs to the group of corticosteroids. It is used for the treatment of inflammatory conditions and autoimmune diseases. This API is used as an impurity standard in analytical methods such as HPLC, and it can be synthesized from natural sources or synthetically. 17-o-(Acetyl-d3)-6-methylprednisolone can also be used in R&D for the development of drugs targeting niche markets, such as those with high purity requirements.
Formula:C24H29D3O6Purity:Min. 95%Molecular weight:419.53 g/molRef: 3D-LDA40194
Discontinued product[5-L-Aspartic Acid]-desmopressin
Desmopressin is a synthetic drug that is used to treat diabetes insipidus and bleeding in patients who are on anticoagulants. It is also used as a diagnostic agent to distinguish between central and nephrogenic diabetes insipidus. Desmopressin is a peptide hormone with amino acid sequence L-Asp-D-Phe-L-Arg-L-Phe. It is synthesized by the combination of two amino acids, L-Aspartic Acid and L-Phenylalanine, which are then linked together through an amide bond. The synthesis of desmopressin occurs in two steps: first, the coupling of amino acid L-Aspartic Acid with the peptide linkage (N-[3-(2'-aminoethyl) carbonyl]glycine) to form the intermediate N-[3-(2'-Aminoethyl) carbonyl]-L-Aspartic Acid; second
Purity:Min. 95%Adefovir dipivoxil dimer
CAS:Adefovir dipivoxil dimer is a synthetic and natural product that is used as an analytical standard for HPLC, as well as in the development of new drug products. It is also used to identify impurities in API. Adefovir dipivoxil dimer has CAS number 323201-05-4 and can be found on the FDA Orange Book.
Formula:C41H64N10O16P2Purity:Min. 95%Molecular weight:1,014.95 g/molRef: 3D-YMA20105
Discontinued productAdx 10059 hydrochloride
CAS:Adx 10059 hydrochloride is a synthetic drug that is used in research and development. It is an impurity standard for the manufacture of drugs and drug products. Adx 10059 hydrochloride is also used as a high-purity reagent in pharmacopoeia and drug development, as well as in analytical chemistry. The compound has been shown to be metabolized by the liver, with metabolites being excreted through urine. This product may also have effects on acetylcholine release, which may make it useful in the treatment of Parkinson's disease.
Formula:C15H14ClFN2Purity:Min. 95%Molecular weight:276.73 g/molRef: 3D-HFB94998
Discontinued productRosuvastatin anhydro lactone
CAS:Rosuvastatin anhydro lactone is a pure chemical compound that is used as an analytical reference standard for high-performance liquid chromatography (HPLC) for the determination of purity and identification of impurities in pharmaceuticals. It is also utilized as a drug development, API impurity, and HPLC standard. Rosuvastatin anhydro lactone is a metabolite of rosuvastatin and is chemically designated as C22H29NO3. The CAS number for rosuvastatin anhydro lactone is 1246665-85-9.
Formula:C22H24FN3O4SPurity:Min. 95%Molecular weight:445.50 g/molRef: 3D-WZB66585
Discontinued productRetinyl retinoate
CAS:Controlled ProductRetinyl retinoate is a synthetic retinoid that is chemically stable and has been shown to be effective in clinical studies. Retinyl retinoate is a lipophilic molecule with antioxidant properties, and it also has the ability to bind to hyaluronic acid and other natural compounds to maintain skin condition. This compound is synthesized by esterification of all-trans-retinoic acid with fatty acids, such as oleic acid or linoleic acid. The chemical structure of this compound can be determined by nuclear magnetic resonance spectroscopy.
Formula:C40H56O2Purity:Min. 95%Molecular weight:568.9 g/molRef: 3D-QAA49886
Discontinued productN-4,5[Acetylamino)methyl]desmopressin
N-4,5[Acetylamino)methyl]desmopressin is a synthetic drug product that is used as an analytical standard for the identification and quantitation of desmopressin in pharmaceutical preparations. It is also used as an impurity standard for HPLC analysis. This product has been synthesized using a custom synthesis process, and has been shown to be suitable for use in drug development and research and development. N-4,5[Acetylamino)methyl]desmopressin is also available as a high purity HPLC standard that meets pharmacopoeia requirements.
Purity:Min. 95%Albendazole sulfone
CAS:Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.
Formula:C12H15N3O4SPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:297.33 g/molRef: 3D-IA17258
Discontinued productDecladinose roxithromycin
CAS:Decladinose roxithromycin is a novel drug that can be used for the diagnosis and treatment of disorders related to the mutation. Decladinose roxithromycin has been shown to be effective in the detection and treatment of mutants, such as those related to cystic fibrosis.
Formula:C33H62N2O12Purity:Min. 95%Molecular weight:678.85 g/molDexamethasone Impurity A
Impurity A is an impurity of the drug product, dexamethasone. The impurity is a natural metabolite of dexamethasone that is found in the urine of patients taking this medication. Impurity A is chemically identified using HPLC and its purity verified using GC-MS and LC-MS. This impurity can be used as a reference standard for analytical purposes and as an impurity standard for pharmacopoeia testing.
Formula:C22H29FO5Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:392.46 g/molMonobenzyl fosaprepitant
CAS:Monobenzyl fosaprepitant is a drug product that is used for research and development purposes. It is an impurity standard for the analysis of API (Active Pharmaceutical Ingredient) impurities, which are synthetic products. Monobenzyl fosaprepitant has been shown to be metabolized in vitro. The metabolism studies have shown that this compound can be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid. Monobenzyl fosaprepitant is a high-purity analytical standard and is used as a pharmacopoeia monograph material.
Formula:C30H28F7N4O6PPurity:Min. 95%Molecular weight:704.50 g/molRef: 3D-PKB85202
Discontinued productPalbociclib Impurity F
CAS:Palbociclib Impurity F is a high purity synthetic intermediate for the production of Palbociclib. It is made by reacting 4-chloro-3-[4-(4-methylpiperidinium)butyl]benzoic acid with 3,5-dichloro-2-hydroxybenzaldehyde in the presence of triethylamine and 2,6-diisopropylaniline. This product has been shown to be metabolized through an oxidation process to form metabolites that are structurally similar to those found in urine. The chemical structure of this impurity can be found in CAS No. 851067-56-6.
Formula:C22H26BrN7OPurity:Min. 95%Molecular weight:484.4 g/molCp-66713 mesylate
CAS:Cp-66713 mesylate is a synthetic drug product with a molecular formula of C17H19NO2 and a molecular weight of 269.34. It has the following CAS number: 91896-58-1. The purity of this compound is >99% (HPLC).
Formula:C15H10ClN5Purity:Min. 95%Molecular weight:295.72 g/molRef: 3D-RDA89658
Discontinued product1-Hydroxy carvedilol
CAS:1-Hydroxycarvedilol is a drug product that is used as a standard in HPLC. It is a natural metabolite of carvedilol and has been found to be involved in the metabolism of carvedilol. The purity of 1-hydroxycarvedilol is >98%. This product is also an impurity standard for analytical purposes and an API impurity. It can also be used in metabolism studies and has CAS No. 146574-41-6.
Formula:C24H26N2O5Purity:Min. 95%Molecular weight:422.50 g/molRef: 3D-WFA57441
Discontinued productDisodium monooctyl sulfosuccinate
CAS:Disodium monooctyl sulfosuccinate (DSMS) is a sodium-based surfactant that is used as an excipient in tablets and capsules. DSMS can be used to treat infectious diseases, such as cholera, dysentery, and typhoid fever. It has been shown to be effective in treating these types of infections due to its long-term efficacy and low potency. The most common side effects of DSMS are mild skin irritation or an allergic reaction. This drug does not have any known contraindications with other drugs or foods. It is also biocompatible with a variety of polymers and fatty acids.
Formula:C12H20Na2O7SPurity:Min. 95%Molecular weight:354.33 g/molRef: 3D-LDA87853
Discontinued product1-Glycoloyl-L-prolinamide
CAS:1-Glycoloyl-L-prolinamide is a drug product that is an analytical standard for the impurity 1-glycoloyl-L-proline (CAS No. 96166-39-1) in the API 1,4,5,6-tetrahydrobenzothiazole (CAS No. 86687-93-0). It has been synthesized to be used as an impurity standard and is provided at a purity of 98.0% or greater by weight. This chemical compound can be used in research and development for the production of drugs as well as in pharmaceutical manufacturing.
Formula:C7H12N2O3Purity:Min. 95%Molecular weight:172.18 g/molRef: 3D-FG167741
Discontinued productDihydrexidine hydrochloride
CAS:Dihydrexidine hydrochloride is a phosphate ion transport inhibitor that binds to the acetylcholine transporter, and inhibits the uptake of acetylcholine in the brain. It is used as an opioid analgesic, as well as to treat depression, cognitive disorders, and Parkinson's disease. Dihydrexidine hydrochloride binds to the catechol-O-methyltransferase (COMT) enzyme and prevents it from breaking down dopamine. This leads to increased levels of dopamine in the synapse and enhanced transmission of nerve impulses between neurons. Dihydrexidine hydrochloride also has been shown to bind to antigen molecules on cells, which may be important for its antiviral properties.
Formula:C17H18ClNO2Purity:Min. 95%Molecular weight:303.8 g/molRef: 3D-IGA70402
Discontinued productHydroxy cyclophosphamide semicarbazone-d4
CAS:Hydroxy cyclophosphamide semicarbazone-d4 is an analytical standard used to monitor the purity of a drug product. It can be used as a reference compound to determine the identity of impurities in a drug product. Hydroxy cyclophosphamide semicarbazone-d4 has been found to be an impurity in some drugs, such as dihydroxycyclophosphamide and hydroxyclorambucil. The chemical name for this substance is 4-[bis(2-chloroethyl)amino]benzoic acid hydroxycyclobutyl ester, and it is used in the synthesis of 3-(1-naphthyl)propionic acid semicarbazide and 2-methyl-2-nitropropane sulfonate. Hydroxy cyclophosphamide semicarbazone-d4 is also a metabolite that is formed when hydroxy cyclophosphamide is broken down by the liver or kidney.
Formula:C8H18Cl2N5O3PPurity:Min. 95%Molecular weight:334.14 g/molRef: 3D-DCA94846
Discontinued productNaproxen Impurity C
CAS:Naproxen Impurity C is an analytical impurity that is found in Naproxen. It is a white crystalline powder with a melting point of 210°C and an assay of 99%. It has been shown to be a metabolite of Naproxen, and may have therapeutic value for the treatment of pain, inflammation, or fever. The purity of this product has been verified by HPLC analysis.
Formula:C14H13BrO3Purity:Min. 95%Molecular weight:309.16 g/molDiltiazem EP Impurity H
CAS:Diltiazem EP Impurity H is a metabolite of diltiazem that is used as an impurity standard for the drug product. Diltiazem EP Impurity H has a purity level of 99% and is soluble in water. It is synthesized by reacting diltiazem with nitric acid, then hydrolyzing the product to form the desired compound. Diltiazem EP Impurity H can be used as an analytical reference material or a pharmacopoeia for HPLC standards.
Diltiazem EP Impurity H is a metabolite of diltiazem that is used as an impurity standard for the drug product. Diltiazem EP Impurity H has a purity level of 99% and is soluble in water. It is synthesized by reacting diltiazem with nitric acid, then hydrolyzing the product to form the desired compound. Diltiazem EP Impurity H can be used as an analytical reference materialFormula:C17H18N2O3SPurity:Min. 95%Molecular weight:330.4 g/molDesisobutyl-N-butyl bortezomib
CAS:Desisobutyl-N-butyl bortezomib is a drug product that has been custom synthesized for the purpose of research and development. The synthetic compound is an impurity standard for the API Desisobutyyl-N-butyl bortezomib. This API is metabolized in both humans and rats, with metabolites being found in urine, feces, and exhaled air. The impurities in this drug product are a result of incomplete synthesis and are not of natural origin.
Formula:C19H25BN4O4Purity:Min. 95%Molecular weight:384.2 g/molRef: 3D-EUB01135
Discontinued productEpi-canagliflozin
CAS:Epi-canagliflozin is a drug product that is manufactured by HPLC. It is a natural, synthetic drug development and research and development of the API impurity standard for analytical. The metabolite of this synthetic API impurity standard is used as an analytical impurity in the pharmacopoeia. This synthetic API impurity standard can be custom synthesized to meet your needs.
Formula:C24H25FO5SPurity:Min. 95%Molecular weight:444.5 g/molRef: 3D-PNC59087
Discontinued productImiloxan hydrochloride
CAS:Imiloxan hydrochloride is a diagnostic agent that is used to diagnose Parkinson's disease and other neurological disorders. Imiloxan hydrochloride has been shown to increase dopamine levels in the brain and improve symptoms of Parkinson's disease. Imiloxan hydrochloride inhibits the glucuronidation of dopamine, which leads to an increase in neurotransmitter levels. This drug also has a pain-relieving effect by increasing norepinephrine levels and blocking the reuptake of serotonin. Imiloxan hydrochloride is a prodrug that is metabolized into methyl-d-aspartate and norepinephrine through conjugation with fatty acids and esters.
Formula:C14H17ClN2O2Purity:Min. 95%Molecular weight:280.75 g/molRef: 3D-GDA16722
Discontinued productFonofos
CAS:Fonofos is a potent inhibitor that has been shown to induce apoptosis in Chinese hamster ovary cells. It is also known to inhibit chitin kinase, a protein that plays an important role in the biosynthesis of chitin, which is essential for the formation of cell walls in fungi and insects. Fonofos has medicinal properties and has been studied as a potential anticancer agent due to its ability to inhibit tumor growth. In vitro studies have shown that Fonofos can inhibit the growth of human cancer cells by inhibiting heparin-binding proteins. Additionally, it has been found to have inhibitory effects on several other enzymes involved in cancer development and progression. Although not approved for use in humans, Fonofos may hold promise as a therapeutic agent for the treatment of certain cancers.
Formula:C10H15OPS2Purity:Min. 95%Molecular weight:246.3 g/molRef: 3D-AAA94422
Discontinued productAlloc bromoridane
CAS:Alloc bromoridane is a drug product that contains the active ingredient bromoridane. Bromoridane is a natural metabolite of the plant alkaloid berberine and has been shown to inhibit the activity of bacterial type IIA topoisomerases from both Gram-positive and Gram-negative bacteria. The chemical name for Alloc bromoridane is 2-[2-(4-bromobenzoyl)phenyl]dihydropyrimidine, and it has CAS number 117348-70-6. Bromoridane is an impurity standard in pharmacopoeias such as USP XXII, European Pharmacopoeia 6th Edition, Japanese Pharmacopoeia 2006, and Chinese Pharmacopoeia 2005. Alloc bromoridane is used in research and development for pharmaceuticals or as an analytical reference material.
Formula:C13H20BrNO4Purity:Min. 95%Molecular weight:334.21 g/molRef: 3D-SEA34870
Discontinued productPravastatin 6-oxo Impurity
CAS:Pravastatin 6-oxo Impurity is an impurity of Pravastatin, a drug used in the treatment of high cholesterol. The impurity has been identified through analytical methods and is characterized by HPLC analysis. This substance has been shown to be present in at least 0.1% of the drug product and may be present as a result of incomplete synthesis or a side-reaction during synthesis.
Formula:C23H34O7Purity:Min. 95%Molecular weight:422.51 g/molCeftazidime impurity H
CAS:Ceftazidime impurity H is a by-product that can be found in the synthesis of ceftazidime. It has been detected using magnetic separation and UV detection. Ceftazidime impurity H is an antibacterial agent that inhibits bacterial growth. This antibiotic binds to the 50S ribosomal subunit, preventing protein synthesis and cell division.
Formula:C23H24N6O7S2Purity:Min. 95%Molecular weight:560.6 g/molRef: 3D-IC63721
Discontinued productN-Methyl formoterol fumarate
CAS:N-Methyl formoterol fumarate is a drug product for the treatment of asthma and chronic obstructive pulmonary disease. It is a synthetic drug that has been approved by the FDA, but is also a metabolite of terbutaline. Metabolism studies have shown that N-methyl formoterol fumarate is an impurity in Terbutaline sulfate and Terbutaline hydrochloride. This drug is not active against bacteria, but may be used as an analytical standard to measure the purity of other drugs.
Formula:C44H56N4O12Purity:Min. 95%Molecular weight:832.94 g/molRef: 3D-VWC13397
Discontinued productDeschloro amlodipine
CAS:Deschloro amlodipine is a drug that is used for the treatment of high blood pressure. It belongs to a group of drugs called calcium channel blockers. Amlodipine has been shown to bind to and inhibit the activity of voltage-gated calcium channels in heart muscle, thereby lowering blood pressure. Deschloro amlodipine is an impurity standard for pharmacopoeia and analytical laboratories. The synthesis of deschloro amlodipine can be customized according to customer requirements. This product will be shipped as soon as possible after purchase.br> br> Desloro amlodipine is metabolized by cytochrome P450 enzymes, including CYP3A4, CYP2C9, and CYP2D6, which are found in the liver and intestines. These enzymes convert desloro amlodipine into two metabolites: 4-hydroxyamlodipine and 4
Formula:C20H26N2O5Purity:Min. 95%Molecular weight:374.43 g/molRef: 3D-NDA15052
Discontinued product(trans)-4-Propyl-1-methyl-L-proline
CAS:(trans)-4-Propyl-1-methyl-L-proline is a synthetic compound that has been used in the past as an impurity standard in the synthesis of several drugs, including metaxalone and aminopyrine. It is also found to have pharmacological effects on its own and was used as a drug product for the treatment of rheumatoid arthritis. (trans)-4-Propyl-1-methyl-L-proline is not listed in any pharmacopoeia or international list of approved drugs.
Formula:C9H17NO2Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:171.24 g/molRef: 3D-FP27224
Discontinued productPyrrolo[1,2-f][1,2,4]triazin-4-amine
CAS:Pyrrolo[1,2-f][1,2,4]triazin-4-amine is a small molecule that inhibits the proliferation of leukemia cells as well as other tumor cells. It inhibits the replication of viruses in vitro and has been shown to inhibit the growth of viruses in cell culture. This compound also binds to phosphonates and can be used as an inhibitor in assays to measure phosphonate activity. Pyrrolo[1,2-f][1,2,4]triazin-4-amine has also been shown to have inhibitory properties against cancer cells in vivo and can be used to treat cancer. In addition, this compound reacts with hydroxyl groups by epimerization reactions and benzyl groups by substitution reactions.
Formula:C6H6N4Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:134.14 g/molRef: 3D-FP55646
Discontinued product1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride
CAS:1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride is a drug product that is not yet approved for use in humans. It is an impurity found in the drug cyclosporine, which is used to treat psoriasis and other skin conditions. 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride has been shown to be inactive in the metabolism studies of rats and dogs. This impurity was detected by HPLC with UV detection at 254 nm, but it did not show any significant absorption at 280 nm. The purity of this compound was determined to be 97% by NMR analysis and HPLC.
Formula:C16H25NO2·HClPurity:Min. 95%Molecular weight:299.84 g/molRef: 3D-IM63866
Discontinued producttert-Butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate
CAS:tert-Butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate is an impurity that is found in the production of tert-butyl 4-(4,5,6,7,8,9,10-hexahydrobenzo[a]pyrido[1,2:4,3]triazin-2(3H)-yl)piperazine-1 carboxylate. It has been used as a reference standard for HPLC. This compound is not active when administered orally and does not exhibit any pharmacological activity.Formula:C19H27N5O4Purity:Min. 95%Molecular weight:389.4 g/molRef: 3D-KAC93966
Discontinued product(1R,2R)-1-(M-Hydroxyphenyl)-2-amino-1-propanol
CAS:Controlled ProductPlease enquire for more information about (1R,2R)-1-(M-Hydroxyphenyl)-2-amino-1-propanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C9H13NO2Purity:Min. 95%Molecular weight:167.2 g/molRef: 3D-WAA48043
Discontinued productRisperidone carboxylate impurity
CAS:Risperidone carboxylate impurity is an analytical reference standard of risperidone that is used in the research and development, drug development, and production of drugs. It can be used as an impurity standard for the manufacture of pharmaceuticals. Risperidone carboxylate impurity has a molecular weight of 514.83 g/mol and a melting point of 200-202°C. Its CAS number is 1346603-86-8. Metabolites are also known to form from risperidone carboxylate impurity during metabolism.
Formula:C24H27FN4O4Purity:Min. 95%Molecular weight:454.50 g/molRef: 3D-WDC60386
Discontinued productcis-Tadalafil
CAS:Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.
Formula:C22H19N3O4Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:389.4 g/molAcarbose Impurity E
CAS:Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.
Purity:Min. 95%N-Desacetyl thiocolchicoside
CAS:N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.
Formula:C25H31NO9SPurity:Min. 95%Molecular weight:521.58 g/molRef: 3D-CHA99181
Discontinued productLinagliptin impurity G
CAS:Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.
Formula:C25H28N8O2Purity:Min. 95%Color and Shape:PowderMolecular weight:472.54 g/mol(3S,4R)-Tofacitinib
CAS:(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.
Formula:C16H20N6OPurity:Min. 95%Molecular weight:312.37 g/molN-Hydroxymethyl Sumatriptan
CAS:N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).
Formula:C15H23N3O3SPurity:Min. 95%Molecular weight:325.43 g/mol(4-Chlorophenyl)diphenylmethanol
CAS:Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C19H15ClOPurity:Min. 95%Molecular weight:294.8 g/molRef: 3D-GAA92289
Discontinued productCiprofloxacin ep impurity C
CAS:Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.
Formula:C15H16FN3O3Purity:Min. 95%Molecular weight:305.30 g/molRef: 3D-DEA22212
Discontinued productEmpagliflozin S-furanose
CAS:Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.
Formula:C23H27ClO7Purity:Min. 95%Color and Shape:PowderMolecular weight:450.91 g/molRef: 3D-IE181148
Discontinued productN-Nitroso dorzolamide
N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.
Formula:C10H15N3O5S3Purity:Min. 95%Color and Shape:PowderMolecular weight:353.44 g/molDesfluoro ezetimibe
CAS:Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.
Formula:C24H22FNO3Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:391.43 g/molTofacitinib dihydro impurity
CAS:Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.
Formula:C16H22N6OPurity:Min. 95%Molecular weight:314.39 g/molPiperacilloic acid
CAS:Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.
Formula:C23H29N5O8SPurity:(Elemental Analysis) Min. 90 Area-%Color and Shape:PowderMolecular weight:535.57 g/molTerbinafine dihydrochloride
CAS:Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.
Formula:C36H40N2Purity:Min. 95%Molecular weight:500.7 g/molRef: 3D-JMB36523
Discontinued productRoflumilast Impurity A
CAS:Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.
Formula:C16H14Cl2N2O3Purity:Min. 95%Molecular weight:353.2 g/mol(S)-Rabeprazole sodium
CAS:(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.
Formula:C18H21N3O3S•NaPurity:Min. 95%Molecular weight:382.43 g/molRef: 3D-IR183125
Discontinued productOxacyclohexane open ring tacrolimus
CAS:Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C44H71NO13Purity:Min. 95%Molecular weight:822.04 g/mol2-(2-Amino-5-bromobenzoyl)pyridine
CAS:2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval
Formula:C12H9BrN2OPurity:Min. 95%Molecular weight:277.12 g/molSacubitril Impurity 2
CAS:Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.
Formula:C24H27NO4Purity:Min. 95%Molecular weight:393.48 g/mol3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride
CAS:3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.
Formula:C19H25ClN2O2Purity:Min. 95%Molecular weight:348.9 g/molRef: 3D-WMD18565
Discontinued productN-Benzyl albuterol
CAS:N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.
Formula:C20H27NO3Purity:Min. 95%Molecular weight:329.4 g/molSimvastatin acid
CAS:Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin
Formula:C25H40O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:436.58 g/molRef: 3D-IS63828
Discontinued productIvermectin impurity I
CAS:Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.
Formula:C48H74O14Purity:Min. 95%Color and Shape:PowderMolecular weight:875.09 g/molRef: 3D-II167729
Discontinued productPramipexole EP Impurity C
CAS:Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Formula:C20H32N6S2Purity:Min. 95%Rocuronium Bromide EP Impurity F Bromide
CAS:Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.Formula:C34H55N2O4·BrPurity:Min. 95%Molecular weight:635.72 g/molDicyclopropylamine hydrochloride
CAS:Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D
Formula:C6H11N•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:133.62 g/molRef: 3D-FD141573
Discontinued productD-6-Cyano-6-norlysergic acid methyl ester
CAS:Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C17H15N3O2Purity:Min. 95%Molecular weight:293.32 g/molRef: 3D-FBA33404
Discontinued productTriethylene glycol flufenamate
CAS:Etofenamate impurity
Formula:C20H22F3NO5Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:413.39 g/molRef: 3D-IT58094
Discontinued productChlorthalidone impurity E
CAS:Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>
Formula:C14H11ClN2O3SPurity:Min. 95%Molecular weight:322.77 g/molRef: 3D-IC76330
Discontinued productAtorvastatin calcium trihydrate EP Impurity G
CAS:Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.
Formula:C34H37FN2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:572.67 g/molGS 441524 triphosphate
CAS:Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.
Formula:C12H12N5O13P3·4NaPurity:(31P-Nmr) Min. 95 Area-%Color and Shape:White PowderMolecular weight:531.20 g/molRef: 3D-FG167050
Discontinued product
