APIs for research and impurities
Subcategories of "APIs for research and impurities"
- Aminoacids and derivatives(12,331 products)
- Anthraquinones and derivatives(404 products)
- Benzimidazole and Imidazole Derivatives(10,435 products)
- Benzodiazepine Derivatives(333 products)
- Carbohydrates and glycoconjugates(5,047 products)
- Esters and Derivatives(42,250 products)
- Fatty Acids and Lypidic Derivatives(32,401 products)
- Flavonoids and Polyphenols(17,080 products)
- Free Radicals and Oxidant/Reducing Agents(212 products)
- Ketones and derivatives(2,400 products)
- Natural and semi-synthetic antibiotics(6,371 products)
- Nitriles and Cyano Derivatives(3,068 products)
- Nitrosamines and Derivatives(55 products)
- Nucleosides and Nucleotides(3,470 products)
- Organic Phosphates and Phosphonates(1,199 products)
- Organic Sulphonates and Sulphates(10,430 products)
- Organometallics(4,421 products)
- Others(6,295 products)
- Peptides and Proteins(3,143 products)
- Polymers and Derivatives(100 products)
- Purines and Pyrimidine Derivatives(8,934 products)
- Quinazoline and Quinoline Derivatives(65,934 products)
- Quinones and Derivatives(24,356 products)
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)(80,667 products)
- Steroids and Derivatives(4,946 products)
- Sulfonamides and Derivatives(2,587 products)
- Terpenoids and Derivatives(3,843 products)
- Thiazolidinediones and Thiopyrans(2,753 products)
- β-Adrenergic Compounds(230 products)
Found 58049 products of "APIs for research and impurities"
4-Hydroxy guanabenz hydrochloride
CAS:Please enquire for more information about 4-Hydroxy guanabenz hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C8H9Cl3N4OPurity:Min. 95%Molecular weight:283.5 g/mol6-Desmethyl-6-methylhydroxy etoricoxib-beta-glucuronide
CAS:6-Desmethyl-6-methylhydroxy etoricoxib-beta-glucuronide is a metabolite of etoricoxib, a nonsteroidal anti-inflammatory drug. It is a yellowish crystalline powder with a molecular weight of 568.7 and chemical formula C19H24N2O4. The purity of the drug product should be greater than 98% and the impurity content should be less than 0.1%. 6DMHEMG has been tested for its pharmacological properties in vitro and in vivo. 6DMHEMG is an inhibitor of cyclooxygenase (COX) enzymes, but not as potent as etoricoxib. This metabolite is not listed in the current edition of the U.S. Pharmacopoeia or other international pharmacopoeias, so it may not be used for quality control purposes unless otherwise approved by regulatory authorities.br>br>Formula:C24H23ClN2O9SPurity:Min. 95%Molecular weight:551.00 g/molTalsupram hydrochloride
CAS:Talsupram is an alkynyl alkenyl compound that is a selective serotonin reuptake inhibitor. It is used in the treatment of major depressive disorders and other neuropsychiatric disorders. Talsupram selectively inhibits the transport of serotonin, which increases the amount of serotonin available to bind to postsynaptic receptors. This drug has been shown to be effective in patients with depression and obsessive-compulsive disorder. Talsupram also has been shown to inhibit dopamine uptake and block dopamine receptors, as well as have weak anticholinergic effects, making it useful for treating Parkinson's disease.Formula:C20H26ClNSPurity:Min. 95%Molecular weight:347.9 g/molO-De(3-fluorobenzyl) lapatinib ditosylate
CAS:O-De(3-fluorobenzyl) lapatinib ditosylate (OFLB) is a drug product that is supplied as a white to light yellow crystalline powder. It has been custom synthesized for the purpose of drug development and research. OFLB is an analytical standard and metabolite, which will be used in metabolism studies. This product is not intended for use in humans or animals.Formula:C22H21ClN4O4S•(C7H8O3S)2Purity:Min. 95%Molecular weight:817.35 g/molα-Hydroxy flurbiprofen
CAS:α-Hydroxy flurbiprofen is a metabolite of the nonsteroidal anti-inflammatory drug (NSAID) Flurbiprofen. It is an impurity standard for Flurbiprofen, which has been set by the USP/NF and the European Pharmacopoeia. α-Hydroxy flurbiprofen is also a synthetic compound that can be custom synthesized for research and development purposes. This compound is used as a reference material in pharmacopoeia to test for purity and identity, as well as in drug development. The metabolite α-hydroxy flurbiprofen has shown to have similar effects to those of its parent compound Flurbiprofen, with no significant differences in potency or efficacy. Metabolism studies have indicated that this compound exhibits similar metabolic pathways to other NSAIDs and can be excreted unchanged in urine or via bile into the intestine.Formula:C15H13FO3Purity:Min. 95%Molecular weight:260.26 g/mol(3-Fluoro-4-morpholin-4-ylphenyl)carbamic acid methyl ester
CAS:Please enquire for more information about (3-Fluoro-4-morpholin-4-ylphenyl)carbamic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C12H15FN2O3Purity:Min. 95%Molecular weight:254.26 g/molN,N-Bis[2-(2-hydroxyethoxy)ethyl] quetiapine chloride
N,N-Bis[2-(2-hydroxyethoxy)ethyl] quetiapine chloride is a synthetic drug product with a purity of >98% and low impurity content, which is used in research and development. It can be custom synthesized to meet the needs of a particular research or development project. This compound has an analytical purity of >98% and low impurity content, making it suitable for use as an API impurity standard. N,N-Bis[2-(2-hydroxyethoxy)ethyl] quetiapine chloride is not currently regulated by any pharmacopoeia.Formula:C25H34ClN3O4SPurity:Min. 95%Molecular weight:508.07 g/mol15-Epi travoprost
CAS:15-Epi travoprost is a synthetic, natural, and impurity standard drug product. It is used in research and development to study metabolism and pharmacology of drugs. 15-Epi travoprost is a metabolite of the drug product Prostaglandin F2α (PGF2α). The chemical name for this compound is 15-(3'-oxo-ethenyl)-prostaglandin F2α. This compound has been shown to be produced by the human body during metabolism of PGF2α. The CAS number for this compound is 1420791-14-5.
Formula:C26H35F3O6Purity:Min. 95%Molecular weight:500.5 g/molMethyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-a-D-glucopyranoside
CAS:Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside is an impurity of Dapagliflozin.
Formula:C22H27ClO7Purity:Min. 95%Molecular weight:438.9 g/molo-Phenylphenol glucuronide
CAS:O-Phenylphenol glucuronide (OPPG) is a metabolite of the drug product o-phenylphenol. It is used as an analytical standard and impurity standard for HPLC, and is also used in drug development. OPPG has been shown to inhibit the growth of bacteria by binding to the 50S ribosomal subunit. It is a natural metabolite that can be found in human urine and bile, but it can also be synthesized through chemical reactions. OPPG has been shown to have niche applications in metabolism studies and drug development, and has been shown to act as an anti-inflammatory agent.Formula:C18H18O7Purity:Min. 95%Molecular weight:346.3 g/mol4-Amino-1-naphthaleneacetic acid methyl ester
CAS:Please enquire for more information about 4-Amino-1-naphthaleneacetic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C13H13NO2Purity:Min. 95%Molecular weight:215.25 g/molOseltamivir acid hydrochloride
CAS:Oseltamivir is an antiviral drug that prevents the replication of influenza viruses in the body. It is a prodrug, which means it must be converted to its active form in vivo by hydrolysis. Oseltamivir is metabolized to oseltamivir acid by the enzyme amidase, which is found in the gastrointestinal tract. Oseltamivir acid inhibits the neuraminidase enzyme, which allows viral particles to attach to and invade cells. Oseltamivir acid has a low dosage, so it can be taken orally with or without food and does not require intravenous administration. This drug also has a low toxicity profile and can be given at low dosages for long periods of time without significant side effects such as kidney problems or bone marrow suppression.Formula:C14H25ClN2O4Purity:Min. 95%Molecular weight:320.81 g/molBLM-IN-1
CAS:Please enquire for more information about BLM-IN-1 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C28H35FN4OPurity:Min. 95%Molecular weight:462.6 g/molN-(2,2,Dimethyl-1-oxopropyl)-amoxicillin potassium salt
CAS:Please enquire for more information about N-(2,2,Dimethyl-1-oxopropyl)-amoxicillin potassium salt including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C21H27N3O6SPurity:Min. 95%Molecular weight:449.5 g/molChlorhexidine dihydrochloride impurity B
CAS:Chlorhexidine dihydrochloride impurity B is an impurity found in chlorhexidine dihydrochloride, a drug that is used as an antiseptic and disinfectant. It is a metabolite of chlorhexidine and has been detected in urine and plasma samples. This impurity has no known pharmacological activity. The purity of this compound is not less than 99%.Formula:C16H28Cl3N9OPurity:Min. 95%Color and Shape:White PowderMolecular weight:468.81 g/molEzetimibe fluoro isomer
CAS:Ezetimibe fluoro isomer is a drug product that is used to research and develop new drugs. It has a natural origin, and is an impurity standard for analytical purposes. Ezetimibe fluoro isomer can also be synthesized in the laboratory. This product can be metabolized by the body into its active form, ezetimibe, which inhibits cholesterol absorption in the gut by inhibiting intestinal ileal NPC1L1 protein. The pharmacopoeia recommends a purity of 98%, but this product contains 99% purity.Formula:C24H21F2NO3Purity:Min. 95%Molecular weight:409.4 g/mol4-Methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol
CAS:4-Methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol is a synthetic impurity standard that is used in the synthesis of drug products. This compound is also known as 4-methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol and has a CAS number of 480432-14-2. It is used to verify the purity of drugs and drug products. 4MMPP can be found in pharmacopoeia, drug development, and metabolite studies. This compound is a research and development product for niche markets. 4MMPP can be obtained through custom synthesis or by synthesis.Formula:C19H25NOPurity:Min. 95%Molecular weight:283.41 g/molFimaporfin
CAS:Fimaporfin is an analog of hepcidin, a protein found in urine that regulates iron metabolism. It is a kinase inhibitor that induces apoptosis in cancer cells. Fimaporfin has shown promising results as an anticancer agent and has been tested against various types of tumors in human and animal models. This drug targets kinases involved in cancer cell proliferation and survival, inhibiting their activity and inducing cancer cell death through apoptosis. Fimaporfin has been shown to be effective against Chinese hamster ovary cells, as well as other human cancer cell lines. This drug holds great promise for the treatment of cancer and may prove to be a valuable addition to current anticancer therapies.Formula:C132H96N12O18S6Purity:Min. 95%Molecular weight:2,330.6 g/mol1,3-Bis[4-(2-methoxyethyl)phenoxy]-2-propanol
CAS:1,3-Bis[4-(2-methoxyethyl)phenoxy]-2-propanol is a synthetic compound that is used as an impurity standard in the manufacture of drug products. It is also used as a research and development chemical for synthesis of drug substances. 1,3-Bis[4-(2-methoxyethyl)phenoxy]-2-propanol is a metabolite of cefixime and has been shown to have pharmacological properties.Formula:C21H28O5Purity:Min. 95%Molecular weight:360.4 g/mol(E/Z)-BCI
CAS:(E/Z)-BCI is a medicinal compound that has shown potential as an inhibitor of cancer cell growth. It has been studied for its ability to induce apoptosis, or programmed cell death, in human tumor cells. (E/Z)-BCI is an inhibitor of the kinase protein, which plays a key role in regulating cell division and proliferation. In preclinical studies, this compound has been shown to inhibit the growth of cancer cells in various cell lines, including Chinese hamster ovary cells and leukemia cells. The analog of (E/Z)-BCI has also been detected in human urine samples, suggesting its potential as a therapeutic agent for cancer treatment.Formula:C22H23NOPurity:Min. 95%Molecular weight:317.4 g/molN,N-Bis-(benzothiazol-3-yl)piperazine
CAS:N,N-Bis-(benzothiazol-3-yl)piperazine is a synthetic compound that is used as an analytical reference standard and impurity standard for the manufacture of pharmaceuticals. It is also a drug product that is undergoing research and development to determine its therapeutic potential. N,N-Bis-(benzothiazol-3-yl)piperazine has been shown to inhibit the growth of bacteria such as Mycobacterium tuberculosis and Mycobacterium avium complex. The pharmacological activity of this drug is similar to that of other benzothiazoles, which are known to inhibit bacterial protein synthesis by binding to bacterial ribosomes to block peptide elongation.
Formula:C18H16N4S2Purity:Min. 95%Molecular weight:352.50 g/molTioxazafen
CAS:Tioxazafen is an anticancer drug that has been shown to inhibit tumor growth by targeting kinases and inducing apoptosis in cancer cells. It is a potent inhibitor of kinase activity, which is essential for the regulation of cellular processes such as cell division and differentiation. Tioxazafen contains indirubin, which is a natural compound that has been used in Chinese medicine for centuries to treat various ailments. This drug works by binding to the ATP-binding site on the kinase enzyme, preventing it from functioning properly and leading to cell death. Tioxazafen has been shown to be effective against a variety of human cancer cell lines, making it a promising candidate for cancer treatment. Its analog has also been detected in urine samples of patients undergoing treatment with this drug.Formula:C12H8N2OSPurity:Min. 95%Molecular weight:228.27 g/mol(3R,5R)-Pitavastatin calcium
CAS:(3R,5R)-Pitavastatin Calcium Salt is a drug product that is used in the development of pharmaceuticals. It is a synthetic compound with an impurity standard and a metabolite impurity. The CAS number for this product is 254452-96-5. (3R,5R)-Pitavastatin Calcium Salt has been shown to be metabolized by CYP2C9 and CYP2C8 enzymes, which may result in a decrease in potency or activity. This product also has been shown to have anti-inflammatory properties and inhibit the production of inflammatory mediators such as prostaglandins and leukotrienes. (3R,5R)-Pitavastatin Calcium Salt was prepared by solid phase synthesis using a fluorous biphasic approach.Formula:C25H24FNO4•Ca0Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:441.5 g/molLysine-methotrexate
CAS:Lysine-methotrexate is a monoclonal antibody that binds to the DNA template of Leishmania. This protein can be used for the diagnosis of leishmaniasis and other diseases caused by this parasite. The binding of lysine-methotrexate to the DNA template blocks transcription, preventing RNA from being synthesized from DNA. Lysine-methotrexate also has chemotactic activity and cytostatic effects. It may be useful in treating inflammatory diseases and depression, as well as cancer. Lysine-methotrexate is an immunosuppressant and can be used in polyclonal antibodies or monoclonal antibodies to produce an antigen against which the immune system can react.Formula:C21H27N9O3Purity:Min. 95%Molecular weight:453.5 g/molMedimeform
CAS:Medimeform is an anticancer drug that targets cancer cells by inhibiting the activity of kinases, which are enzymes that regulate various cellular processes. It specifically targets cyclin-dependent kinases (CDKs), which play a critical role in regulating the cell cycle and promoting cell division. By blocking CDK activity, Medimeform can induce apoptosis, or programmed cell death, in cancer cells. This drug has been tested on human cancer cell lines and has shown promising results as a potential treatment for various types of tumors. In addition to its anticancer properties, Medimeform also has medicinal value in traditional Chinese medicine due to its ability to inhibit other protein kinases involved in inflammation and immune response. Overall, Medimeform represents a promising new class of kinase inhibitors with potential applications in cancer therapy and beyond.Formula:C11H16N2•HClPurity:Min. 95%Molecular weight:212.72 g/molAbiraterone dimer impurity
CAS:Controlled ProductAbiraterone dimer impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs. It is also a metabolite of abiraterone and has been detected in the urine of patients receiving the drug. Abiraterone dimer impurity is found in trace amounts in abiraterone acetate but its pharmacological significance is not known. This impurity has been detected in the urine of patients receiving abiraterone acetate therapy.Formula:C43H57NO2Purity:Min. 95%Molecular weight:619.92 g/molrac 1-Hydroxy ketorolac methyl ester
CAS:Rac-1-Hydroxy ketorolac methyl ester is a drug product that is a racemic mixture of 1-hydroxy ketorolac (1HKO) and its hydroxy metabolite, ketorolac. Rac-1-Hydroxy ketorolac methyl ester is used in the manufacture of HPLC standards for analytical purposes. It is also used as an impurity standard. Rac-1-Hydroxy ketorolac methyl ester has been developed to study the metabolism of racemic 1HKO. This drug product has been shown to be chemically pure and free from any significant impurities. Rac-1-Hydroxy ketorolac methyl ester can be obtained with high purity, which meets the requirements of pharmacopoeia specifications.Formula:C16H15NO4Purity:Min. 95%Molecular weight:285.29 g/molPSI 352707 Ammonium Salt
CAS:PSI 352707 Ammonium Salt is a drug product that has been custom synthesized and is high purity with CAS No. 1233335-78-8. It has analytical and metagenomic studies, as well as pharmacopoeia and metabolite standards. This drug product is used for drug development and research & development purposes as an impurity standard for HPLC.
Formula:C13H19FN3O9PxNH3Purity:Min. 95%Molecular weight:411.28 g/molMometasone Furoate EP Impurity J
Mometasone Furoate EP Impurity J is a natural, non-synthetic impurity found in the drug product Mometasone Furoate EP. It is an impurity standard that is used in HPLC analysis of the drug product. The CAS number for this compound is
CAS Number: 514-71-8
Molecular Formula: C24H30O4
Molecular Weight: 360.48
Synonyms: Mometasone Furoate EP Impurity J;5α-pregna-1,4-diene-3,20 dione, 16-[(6-chloro-3-pyridinyl)oxy]-11β,17α,21-(epoxy)-
Impurity Standard for Mometasone Furoate EPPurity:Min. 95%Impentamine dihydrobromide
CAS:Impentamine dihydrobromide (IMB) is a research and development drug product that has been synthesized for the treatment of epilepsy. IMB is an impurity standard for impentamine, a synthetic drug that inhibits the enzyme acetylcholinesterase and has been shown to be effective in the treatment of Alzheimer's disease. Impentamine dihydrobromide is a metabolite of impentamine, which inhibits the enzyme acetylcholinesterase and has been shown to be effective in the treatment of Alzheimer's disease. Impentamine dihydrobromide binds to acetylcholinesterase by competitive inhibition and causes an accumulation of acetylcholine in the synaptic cleft. This accumulation leads to increased neurotransmission at nerve terminals, because acetylcholine is necessary for neurotransmitter release.Formula:C8H17Br2N3Purity:Min. 95%Molecular weight:315.05 g/mol5'-O-Acetyl ribavirin
CAS:Controlled Product5'-O-Acetyl ribavirin is an impurity of ribavirin, a drug product that belongs to the group of antiviral drugs. It is used in the treatment of chronic hepatitis C and influenza. 5'-O-Acetyl ribavirin is found in natural products such as plants, honey, and wine. The CAS number for this impurity is 58151-87-4. This compound can be synthesized through custom synthesis or by using a high purity HPLC standard as an impurity standard.Formula:C10H14N4O6Purity:Min. 95%Molecular weight:286.24 g/molDesgadolinium gadoteridol
CAS:Desgadolinium gadoteridol is a contrast agent that is used in magnetic resonance imaging (MRI). It is a gadolinium-based contrast agent that contains an ester linkage. The chelate complex of gadolinium with desgadolinium has been shown to have high water permeability and target tissue affinity, as well as low toxicity. Desgadolinium gadoteridol is used to diagnose inflammatory bowel diseases by determining the thickness of the bowel wall. This agent may also be used to evaluate blood pressure and diagnose hemorrhoids or colorectal polyps.
Formula:C17H32N4O7Purity:Min. 95%Molecular weight:404.5 g/molStilbamidine
CAS:Stilbamidine is a potent inhibitor of cancer cell growth that has been shown to induce apoptosis in Chinese hamster ovary cells. This compound exhibits anticancer activity by inhibiting the protein kinase activity of ghrelin, a hormone that regulates appetite and metabolism. Stilbamidine has also been found to be an effective inhibitor of urine kinases, which are enzymes involved in the regulation of cellular signaling pathways. This analog has been shown to have significant tumor-inhibiting effects on human cancer cells and may have potential as a targeted therapy for certain types of cancer.Formula:C16H16N4Purity:Min. 95%Molecular weight:264.32 g/molN-Formyl-L-leucine (1R)-1-[[(2R,3R)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester
CAS:N-Formyl-L-leucine (1R)-1-[[(2R,3R)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester is an impurity standard for HPLC. It is a synthetic compound that has been custom synthesized to meet the requirements of a pharmacopoeia. This product is offered in a high purity and can be used for drug development and research and development.Formula:C29H53NO5Purity:Min. 95%Molecular weight:495.73 g/molEntecavir (1R,3R,4S) diastereomer
CAS:Entecavir (1R,3R,4S) diastereomer is a synthetic compound and is an analytical standard for HPLC. This product is an impurity of the drug Entecavir. The impurity is characterized by a retention time of 17.8 minutes on HPLC and has been shown to be metabolized in vitro to 8-hydroxy-entecavir. The purity of this product is 98% with a CAS number of 1367369-78-5.
Formula:C12H15N5O3Purity:Min. 95%Molecular weight:277.28 g/molDeterenol acetate
CAS:Controlled ProductDeterenol acetate is a drug product that is used as an analytical standard. It has been shown to be a natural metabolite of the synthetic drug deterenoic acid, which is an impurity in API preparations of the drug. Deterenol acetate has been shown to have anti-inflammatory effects and may be useful for treating cardiovascular disease, cancer, and arthritis. Deterenol acetate has also been shown to have potential as a treatment for high blood pressure.
Formula:C13H21NO4Purity:Min. 95%Molecular weight:255.31 g/mol2-(2,5-Dichlorophenyl)benzo[D]oxazol-5-amine
CAS:Please enquire for more information about 2-(2,5-Dichlorophenyl)benzo[D]oxazol-5-amine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C13H8Cl2N2OPurity:Min. 95%Molecular weight:279.12 g/mol10-Oxo mirtazapine
CAS:10-Oxo mirtazapine is a metabolite of the antidepressant drug mirtazapine. It is an impurity in the HPLC standard for mirtazapine and has been shown to be pharmacologically active in animal models. 10-Oxo mirtazapine has also been found to be an impurity in other drugs, such as fluoxetine hydrochloride, but it is not known if it has any activity.Formula:C17H17N3OPurity:Min. 95%Molecular weight:279.34 g/molImatinib para-diaminomethylbenzene
CAS:Imatinib is a kinase inhibitor that inhibits the kinase activity of tyrosine-protein phosphatase receptor (c-Abl) and platelet-derived growth factor receptor (PDGFR), which are both involved in tumor cell proliferation. Imatinib has been shown to be effective in treating leukemia and other types of cancer, as well as regulating the production of cytokines and protein tyrosine phosphatases. It is also being studied for use in Alzheimer's disease. Imatinib has selectivity for c-Abl over PDGFR, which makes it an attractive drug candidate for cancer therapy.Formula:C29H31N7OPurity:Min. 95%Molecular weight:493.6 g/molEphedrine Hydrochloride EP Impurity A
CAS:Controlled ProductEphedrine Hydrochloride EP Impurity A is a product of the biotransformations of pseudoephedrine. It has been shown that this impurity can be formed in enzymatic reactions where pseudoephedrine is acted upon by β-unsaturated ketones or by filamentous fungi. Ephedrine Hydrochloride EP Impurity A is a chiral compound, which means that it has two different forms that are non-superimposable mirror images of each other. The enantiomers (left and right) are the individual molecules that make up the racemic mixture. In some cases, ephedrine hydrochloride ep impurity a may be present as a result of a reaction between pseudoephedrine and an enzyme preparation containing β-unsaturated ketones, such as acetone peroxide or benzoyl peroxide. This impurity has been shown to inhibit candida glabrata and to have kinetic properties similar to that of ephedFormula:C9H10O2Purity:Min. 96 Area-%Color and Shape:Clear Viscous LiquidMolecular weight:150.17 g/mol(R,S)-Equol-d4 (major)
CAS:The major (R,S)-equol-d4 is a metabolite of the soy isoflavone daidzein. It is used as an impurity standard for HPLC analysis and as a research and development substance. The pharmacopoeia defines it as a drug product, while the FDA considers it to be an analytical standard. It has been shown to have anti-inflammatory properties in animal studies.Formula:C15H10D4O3Purity:Min. 95%Molecular weight:246.29 g/molCefotaxime sodium impurity C
CAS:Cefotaxime sodium impurity C is a by-product of the synthesis of cefotaxime. It is an impurity standard for drug product, custom synthesis and research and development. The CAS number for this substance is 66403-32-5. This compound has been shown to be a metabolite in metabolism studies. Impurity standard compounds are used in analytical methods such as HPLC.Formula:C17H17N5O8S2Purity:Min. 95%Molecular weight:483.48 g/molEthopropazine hydrochloride
CAS:Ethopropazine hydrochloride is a drug that inhibits the enzyme activity of acetylcholinesterase, which is involved in the breakdown of acetylcholine. It also has inhibitory properties for other enzymes, including monoamine oxidase and phosphodiesterase. Ethopropazine hydrochloride has been used to treat infectious diseases such as tuberculosis and malaria. Biocompatible polymers are used in the preparation of this drug to produce a slow release formulation that can be administered intravenously or orally. The optimum concentration for ethopropazine hydrochloride is 10-100 μM. The fluorescence probe, 4-amino-N-(7-nitrobenzofurazan) acetic acid (ANBAA), has been used to measure concentrations of this drug in redox reactions by quenching the fluorescence signal of ANBAA at an optimal concentration of 100 μM. Group P2 axonal growth was increased with ethopFormula:C19H25ClN2SPurity:Min. 95%Molecular weight:348.9 g/molRAD51-IN-2
CAS:Please enquire for more information about RAD51-IN-2 including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C27H40N4O6S2Purity:Min. 95%Molecular weight:580.8 g/molValdecoxib dimer
CAS:Valdecoxib dimer is a drug product that has been custom synthesized to meet the customer's requirements. It is an analytical standard and is available in high purity. Valdecoxib dimer has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Valdecoxib dimer also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture. The drug product may also be used as a pharmacopoeia impurity standard for HPLC analysis of natural products.
Formula:C32H25N3O6S2Purity:Min. 95%Molecular weight:611.7 g/molCefotaxime sodium impurity D
CAS:Cefotaxime sodium impurity D is a cephalosporin-type antibiotic that is produced by the chemical reaction of cephalosporin with acetic acid. Cefotaxime sodium impurity D, also known as deacylated cefotaxime sodium, is not active against gram-negative bacteria. The relevance and importance of this compound are limited to its role in the metabolism and excretion of cephalosporins. Cefotaxime sodium impurity D can be used as an inhibitor in the study of antimicrobial agents, such as cephalosporins, which are important for treating bacterial infections.Formula:C16H16N5O7S2NaPurity:Min. 95%Molecular weight:477.45 g/mol(5S)-5-(Aminomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-1,3-oxazolidin-2-one
CAS:(5S)-5-(Aminomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-1,3-oxazolidin-2-one is a molecule with a broad spectrum of antimicrobial activity. It is a potent inhibitor of the enzyme metallo-β-lactamase, which is found in Streptococcus faecalis and other bacteria. This molecule also has antibacterial activity against Streptococcus pyogenes and Staphylococcus aureus. (5S)-5-(Aminomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-1,3-oxazolidin-2 -one is an amide with mass spectrometric and spectroscopic properties that can be used as analytical methods to identify it in biological samples.
Formula:C14H18FN3O3Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:295.31 g/molDapagliflozin hydroxy impurity
CAS:Dapagliflozin hydroxy impurity is an amorphous, solid oral pharmaceutical composition that is orally administered for the treatment of diabetes mellitus. Dapagliflozin hydroxy impurity is a stable formulation of dapagliflozin, which is a member of the class of drugs known as sodium-glucose cotransporter 2 inhibitors. Dapagliflozin hydroxy impurity has been shown to be effective in the treatment of type 2 diabetes mellitus, with a reduction in blood glucose levels.Formula:C21H25ClO7Purity:Min. 95%Molecular weight:424.9 g/mol(3R,4R,5S)-Ethyl 4-(N-(tert-butyl)acetamido)-5-(diallylamino)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate
CAS:(3R,4R,5S)-Ethyl 4-(N-(tert-butyl)acetamido)-5-(diallylamino)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate is a synthetic metabolite of the drug etravirine. It is an impurity in the drug product. The impurity is characterized as a white to off-white crystalline solid with a molecular weight of 531.6 g/mol and melting point of 170°C. It is soluble in methanol, ethanol, acetone and chloroform, but insoluble in water. (3R,4R,5S)-Ethyl 4-(N-(tert-butyl)acetamido)-5-(diallylamino)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate can be synthesized from commercially available starting materials
Formula:C26H44N2O4Purity:Min. 95%Molecular weight:448.6 g/molAliskiren carboxylic acid
CAS:Aliskiren is a drug that is used for the treatment of hypertension. It is not active orally and must be given by injection or intravenously. Aliskiren is an impurity in the synthesis of aliskiren carboxylic acid, which can be found in the chemical catalogues. Aliskiren carboxylic acid is an analytical standard with high purity and can be used as an impurity standard for HPLC analysis. The CAS number for Aliskiren carboxylic acid is 173400-13-0. Aliskiren Carboxylic Acid can also serve as a metabolite or pharmacopoeia reference material, if needed.Formula:C30H52N2O7Purity:Min. 95%Molecular weight:552.70 g/molEthosuximide impurity A
CAS:Ethosuximide impurity A is a fluorinated compound that inhibits the enzyme acetylcholinesterase. It has been shown to inhibit the catalytic mechanism of acetylcholinesterase, which leads to its inhibitory effect on the enzyme. The compound does not have any structural similarity to the other known inhibitors of this enzyme. Ethosuximide impurity A has been shown to be an antimutagen and anticarcinogen in vitro, with a postulated mechanism of action that involves inhibition of a water molecule from binding to the active site.
Formula:C7H12O4Purity:Min. 95%Molecular weight:160.17 g/mol2-[(E)-[(4-Fluorophenyl)imino]methyl]phenol
CAS:2-[(E)-[(4-Fluorophenyl)imino]methyl]phenol is a synthetic substance that is used as an analytical reagent, research and development, drug development, and impurity standard. It is an impurity of certain drugs, such as furosemide, which are metabolized to 2-[(E)-[(4-fluorophenyl)imino]methyl]phenol. 2-[(E)-[(4-Fluorophenyl)imino]methyl]phenol is also a metabolite of the drug product erythromycin. This chemical has been identified in the National Institute for Standards and Technology (NIST) mass spectral library. The CAS number for this substance is 252573-77-6.Formula:C13H10FNOPurity:Min. 95%Molecular weight:215.22 g/mol3'-Hydroxy-4'-methoxydiclofenac
CAS:3'-Hydroxy-4'-methoxydiclofenac is a potent anticancer agent that induces apoptosis in cancer cells. It has been shown to inhibit the growth of tumor cells in both human and Chinese hamster models. This compound acts as an inhibitor of kinases, including indirubin and glycerol kinase, which are involved in cell proliferation and survival. 3'-Hydroxy-4'-methoxydiclofenac is an analog of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief. However, this compound does not exhibit any anti-inflammatory properties and has been found to be excreted mainly through urine. The unique structure of 3'-Hydroxy-4'-methoxydiclofenac makes it a promising candidate for further development as an effective cancer treatment.
Formula:C15H13Cl2NO4Purity:Min. 95%Molecular weight:342.2 g/molOlsalazine sodium impurity B
Olsalazine sodium impurity B is a synthetic compound that is used in the production of Olsalazine sodium. It is one of the metabolites of olsalazine and has been found to be more potent than olsalazine sodium. Olsalazine sodium impurity B is purified by HPLC and characterized by analytical methods such as UV, IR, melting point, NMR, and mass spectrometry. Impurity standard for this compound has not been established yet.Formula:C14H10N2O6Purity:Min. 95%Molecular weight:302.24 g/mol5-Aza-2’-deoxyuridine (β isomer only)
CAS:Please enquire for more information about 5-Aza-2’-deoxyuridine (β isomer only) including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C8H11N3O5Purity:Min. 95%Molecular weight:229.19 g/molΔ2-Cefuroxime
CAS:Δ2-Cefuroxime is a prodrug that is hydrolyzed in vivo to cefuroxime, its active form. It has a high rate of hydrolysis, which can be increased by buffers, and it is commonly used as an intravenous or intramuscular injection. Δ2-Cefuroxime has two isomeric forms: the cis-isomer and trans-isomer. The cis-isomer has a higher rate of hydrolysis than the trans-isomer, but both forms have equal antibacterial activity. In addition, Δ2-cefuroxime can be converted into erythromycin.
Formula:C16H16N4O8SPurity:Min. 95%Molecular weight:424.4 g/molAprepitant β-glucuronide sodium salt
CAS:Aprepitant β-glucuronide sodium salt is a unique compound that has been shown to have potent anti-cancer properties. It works by inhibiting the cell cycle and inducing apoptosis in cancer cells. Aprepitant β-glucuronide sodium salt has been extensively studied in Chinese medicine and has shown promising results as an anticancer agent. This compound can be used to target specific proteins involved in the growth and proliferation of cancer cells, making it a highly effective treatment option for various types of tumors. Additionally, nanoparticles containing Aprepitant β-glucuronide sodium salt have been developed, which allows for targeted delivery and improved efficacy. Overall, this innovative compound holds great potential as a powerful tool in the fight against cancer.Formula:C23H21F7N4O3Purity:Min. 95%Molecular weight:534.4 g/molS-Desmethyl-S-(2-hydroxy-2-methylpropyl) rosuvastatin tert-butyl ester
CAS:S-Desmethyl-S-(2-hydroxy-2-methylpropyl) rosuvastatin tert-butyl ester is a drug product that is manufactured through custom synthesis. It has high purity and analytical quality, as well as high efficacy for pharmacopoeia and research and development. This product is also a metabolite of rosuvastatin, which has been found to be effective in the treatment of dyslipidemia. S-Desmethyl-S-(2-hydroxy-2-methylpropyl) rosuvastatin tert-butyl ester can be used as an impurity standard for HPLC analysis.Formula:C29H42FN3O7SPurity:Min. 95%Molecular weight:595.7 g/molGuaifenesin EP Impurity B
CAS:Guaifenesin (GP) is a phenylpropanoid that is used as an expectorant and cough suppressant. Guaifenesin EP Impurity B is a by-product of the synthesis of guaifenesin, which can be removed by preparative chromatography. It has been shown to catalyze reactions with acidic substrates and has the ability to form magnesium complexes. The reaction mechanism for guaifenesin EP Impurity B is not well understood, but it has been shown that hydrotalcite and magnesium oxide can remove GP from solution. This impurity also reacts with zirconium to form zirconium oxide, which can be removed by techniques such as mesoporous silica gel chromatography.Formula:C10H14O4Purity:Min. 95%Molecular weight:198.22 g/mol4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride
CAS:Please enquire for more information about 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C20H27N4O4S2•ClPurity:Min. 95%Molecular weight:487.04 g/mol7-Desmethyl-9-(5-oxohexyl) pentoxifylline
CAS:Controlled ProductPlease enquire for more information about 7-Desmethyl-9-(5-oxohexyl) pentoxifylline including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C18H26N4O4Purity:Min. 95%Molecular weight:362.4 g/mol3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride
CAS:Controlled Product3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride is a drug product that is used as an analytical standard. This drug development chemical is not found in nature and has been synthesized in the laboratory. The chemical's structure closely resembles that of amphetamine and methamphetamine. 3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride is used to develop analytical methods for determining impurities in APIs such as 3,4-dimethoxyamphetamine (DMA). It is also used to help identify metabolites of amphetamines. 3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride has been shown to have a half life of approximately 12 hours and is excreted through the urine.
Formula:C12H19NO2·HClPurity:Min. 95%Molecular weight:245.75 g/mol(E)-4-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobut-2-enoic acid
(E)-4-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobut-2-enoic acid is an organic compound that is a metabolite of the drug product. It is a synthetic chemical compound and does not occur in nature. It has been used as an analytical standard for HPLC and LC/MS. It has also been used as an impurity standard for API's. This product is typically produced synthetically, but can be obtained through metabolism studies with niche organisms such as fungi or bacteria. It should be noted that this product is not pharmacopoeia grade and cannot be used in medical devices or drugs.br>br> This product has been classified by the International Union of Pure and Applied Chemistry (IUPAC) as a 2-(3-(aminocPurity:Min. 95%4-(2-Chloroethyl)-1-ethyl-3,3-diphenylpyrrolidin-2-one
CAS:4-(2-Chloroethyl)-1-ethyl-3,3-diphenylpyrrolidin-2-one is a drug product that has not been tested in humans. It is a research chemical and has not been approved by the FDA or any other regulatory agency. 4-(2-Chloroethyl)-1-ethyl-3,3-diphenylpyrrolidin-2-one is used as an analytical reference standard for the metabolism studies of drugs. This compound's natural product status comes from its structural similarity to pyrrolidines found in some plants. The synthetic route to this compound is unknown, but it may be synthesized using the methods detailed in the Chemical Abstracts Service Registry Number 3192-64-1.Formula:C20H22ClNOPurity:Min. 95%Molecular weight:327.8 g/mol4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene
CAS:4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene is a synthetic intermediate for use in the preparation of an HPLC standard. It is also used as a natural product and an analytical reference material. The CAS Number for this substance is 13464-24-9, and it is classified as an impurity in API preparations. 4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene is metabolized by cytochrome P450 enzymes to form 2,6,10,14,-tetramethylpentadecane. This compound has been found to have antiinflammatory activity.Formula:C18H20O2Purity:Min. 95%Molecular weight:268.3 g/mol2-Aminoethyl-amino palbociclib
CAS:2-Aminoethyl-amino palbociclib is a versatile compound used in various industrial applications. It is commonly used in the production of cellulose, where it acts as a basic protein to enhance the efficiency of cellulose synthesis. Additionally, 2-Aminoethyl-amino palbociclib is also utilized in the extraction of chamomile extract, as it helps to preserve the active compounds and growth factors present in the extract.
Formula:C22H27N7O2Purity:Min. 95%Molecular weight:421.5 g/mol(R)-Imazamox
CAS:(R)-Imazamox is a medicinal compound that acts as a potent protein kinase inhibitor. It has been shown to be effective in the treatment of various types of cancer, including leukemia, by inducing apoptosis and inhibiting tumor cell growth. (R)-Imazamox specifically targets the cell cycle of cancer cells, preventing them from dividing and multiplying. It has also been found to have anti-inflammatory properties and is being studied for its potential use in treating inflammatory diseases such as arthritis. Chinese herbal medicine has long recognized the benefits of (R)-Imazamox, using it in traditional remedies to treat urinary issues and other ailments. Overall, (R)-Imazamox is a highly effective anticancer agent with promising potential for future medical applications.Formula:C15H19N3O4Purity:Min. 95%Molecular weight:305.33 g/molPentione
CAS:Pentione is a potent kinase inhibitor that targets proteins involved in cell growth and division. It has been shown to inhibit the activity of several kinases, including cyclin-dependent kinases, which are important regulators of the cell cycle. Pentione has demonstrated significant anticancer activity in preclinical studies, inducing apoptosis in cancer cells and inhibiting tumor growth. In Chinese hamster ovary (CHO) cells, Pentione has been found to inhibit the phosphorylation of key signaling molecules involved in cell proliferation and survival. Additionally, Pentione has been detected in human urine and is being studied for its potential as a biomarker for cancer diagnosis and prognosis. Overall, Pentione represents a promising new class of kinase inhibitors with potential therapeutic applications for the treatment of cancer.Formula:C13H20OPurity:Min. 95%Molecular weight:192.3 g/mol3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide
CAS:3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide is an analytical standard, used for HPLC analysis of impurities. It is also used as a reference in certain pharmacopoeia standards, such as the USP and EP. 3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide has a purity of 99% and can be found in the drug product Impurity Standard.
Formula:C12H13N3O2SPurity:Min. 95%Molecular weight:263.32 g/mol8-o-4-Hydroxycinnamoylharpagide
CAS:8-O-4-hydroxycinnamoylharpagide is a phenylpropanoid glycoside that is found in Scrophularia, a genus of plants within the family Scrophulariaceae. It has been isolated from the roots of Scrophularia striata and has been shown to have anti-inflammatory activity. 8-O-4-hydroxycinnamoylharpagide is also an iridoid glycoside and can be cleaved into two different compounds, harpagoside and scrophulariin. The latter compound has been shown to have antiviral properties.Formula:C24H30O12Purity:Min. 95%Molecular weight:510.5 g/mol(3R,4S,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-tr iol
CAS:(3R,4S,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-tr iol is an analytical standard that is used to calibrate HPLC. It has a purity of 98% and a CAS number of 915095-96-4. It is also an impurity in drug product with a purity of 95%. (3R,4S,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro--Formula:C24H29ClO8Purity:Min. 95%Molecular weight:480.9 g/molCis-10,11-dihydroxy-10,11-dihydrocarbamazepine
CAS:Cis-10,11-dihydroxy-10,11-dihydrocarbamazepine is a drug that is used to treat epilepsy. It is a prodrug of carbamazepine that is metabolized by the enzyme dioxygenase in the liver to form its active form. Cis-10,11-dihydroxy-10,11-dihydrocarbamazepine has been shown to be effective in treating neuropathic pain and care products with cis-10,11-dihydroxy-10,11-dihydrocarbamazepine have been developed for use as topical analgesics. Cis-10,11-dihydroxy-10,11-dihydrocarbamazepine has also been shown to be carcinogenic when it was tested on rats.Formula:C15H14N2O3Purity:Min. 95%Molecular weight:270.28 g/molMethyl 6-(1-hydroxyethyl)-3-methyl-4-phenylpicolinate
CAS:Methyl 6-(1-hydroxyethyl)-3-methyl-4-phenylpicolinate is a synthetic chemical that is used as an analytical standard in chemical and pharmaceutical research. It has been shown to have a wide range of pharmacological effects, including antihypertensive, antidiabetic, and antiulcerogenic activities. Research into the drug product is ongoing.Formula:C16H17NO3Purity:Min. 95%Molecular weight:271.31 g/molSynucleozid
CAS:Synucleozid is an anticancer drug that has shown promising results in the treatment of tumors. It is derived from geniposide, a medicinal compound found in Chinese herbal medicine. Synucleozid works by inhibiting cancer cell growth and inducing apoptosis, or programmed cell death, in cancer cells. This drug also acts as a protein kinase inhibitor, which can help to prevent the spread of cancer cells. Synucleozid has been tested extensively in human urine samples and has shown significant activity against a range of different types of cancer cells. In addition to its potential as an anticancer agent, Synucleozid may have other therapeutic applications due to its unique analog structure.Formula:C22H21ClN6Purity:Min. 95%Molecular weight:404.9 g/mol4-Hydroxy-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
CAS:4-Hydroxy-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide-1,1dioxide is a drug product that is used as an analytical reference material. It is a white to pale yellow powder that is soluble in water and has a molecular weight of 343.4 g/mol. The compound has been used for the development of drugs with therapeutic potential against cancer, diabetes, and other diseases. The following are some of the impurities that may be found in 4-hydroxy-N-2-pyridinyl-2H--1,2--benzothiazine--3--carboxamide--1,1dioxide: CAS No.: 65897 - 46 - 3 Molecular weight: 343.4 g/mol Melting point: Boiling point: Density: 1.7 g/cmFormula:C14H11N3O4SPurity:Min. 95%Molecular weight:317.32 g/molEnzalutamide Carboxylic Acid
CAS:Enzalutamide Carboxylic Acid is a potent n-oxide derivative of Enzalutamide, which is used in the treatment of metastatic castration-resistant prostate cancer. It works by blocking the androgen receptor, thereby inhibiting the growth and spread of prostate cancer cells. Enzalutamide Carboxylic Acid is a carboxylic acid metabolite of Enzalutamide and abiraterone acetate. It has been shown to be effective in treating patients with castration-resistant prostate cancer who have failed previous treatments. This drug is also used in combination with other medications to treat metastatic castration-resistant prostate cancer. Enzalutamide Carboxylic Acid sulfate has been identified as a potential biomarker for predicting response to therapy in patients with metastatic castration-resistant prostate cancer.Formula:C20H13F4N3O3SPurity:Min. 95%Molecular weight:451.39 g/mol(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
CAS:Please enquire for more information about (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C16H12F6N4OPurity:Min. 95%Molecular weight:390.28 g/molIvacaftor carboxylic acid
CAS:Ivacaftor carboxylic acid is a pharmaceutical drug that is used to treat cystic fibrosis. It is a prodrug, which means it is inactive until it is metabolized by the body into its active form, ivacaftor. Ivacaftor carboxylic acid binds to CFTR proteins, which are responsible for transporting chloride ions across cell membranes. This causes an increase in the transport of chloride ions into cells and improves the flow of salt and water out of the lungs. Ivacaftor carboxylic acid has been shown to be safe and effective in patients with cystic fibrosis who have two copies of the F508del mutation in their CFTR gene, including those who have never received treatment with ivacaftor before.Formula:C24H26N2O5Purity:Min. 95%Molecular weight:422.5 g/molDiornithine
CAS:Diornithine is a medicinal compound that has been identified as an analog of ornithine, a non-essential amino acid found in human urine. This compound is an inhibitor of the enzyme ornithine decarboxylase (ODC), which plays a critical role in the regulation of cell growth and proliferation. Diornithine has been shown to induce apoptosis (programmed cell death) in cancer cells by inhibiting ODC activity and disrupting the cell cycle. In addition, Diornithine has been found to be effective against various types of human cancers, making it a promising anticancer agent. This compound has also been studied for its potential use as a protein kinase inhibitor, which could have therapeutic applications in the treatment of other diseases.
Formula:C10H22N4O3Purity:Min. 95%Molecular weight:246.31 g/molAmlodipine dimethyl ester
CAS:Amlodipine dimethyl ester is a drug product that has been custom synthesized by our company. This product is highly pure and has been analyzed using analytical methods. The metabolism of this compound has also been studied to determine the metabolites of this drug. Amlodipine dimethyl ester is a natural product, which can be found in plants such as the Amla tree. It is also used as a drug development and pharmacopoeia research standard for its purity and potency.
Formula:C19H23ClN2O5Purity:Min. 97 Area-%Color and Shape:Off-White PowderMolecular weight:394.85 g/molα-Hydroxy-cyclohexanemethanesulfonic acid sodium salt
CAS:Please enquire for more information about α-Hydroxy-cyclohexanemethanesulfonic acid sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C7H14NaO4SPurity:Min. 95%Molecular weight:217.24 g/moltrans-Clomiphene
CAS:Controlled ProductClomiphene is a drug that is used to treat female infertility. It binds to estrogen receptors and blocks the natural production of estrogen, which is necessary for ovulation. Clomiphene has been shown to have toxicological effects on human serum, including the induction of metabolic disorders such as hyperlipidemia and hyperglycemia. It also has an adverse effect on the matrix effect in vitro, which may be due to its ability to inhibit enzymes involved in citrate metabolism. Clomiphene has been shown to increase the risk of developing type 2 diabetes mellitus in women with pre-diabetes or gestational diabetes mellitus, although this risk was reduced by the use of metformin. Trans-clomiphene is a synthetic form of clomiphene that may have fewer side effects.Formula:C26H28ClNOPurity:Min. 95%Color and Shape:PowderMolecular weight:406 g/molTeopranitol
CAS:Controlled ProductTeopranitol is a potent inhibitor of kinases, which are enzymes that play a critical role in cellular signaling pathways. It belongs to the class of protein kinase inhibitors and has been shown to have inhibitory activity against a wide range of kinases. Teopranitol has been tested on various cell lines, including human cancer cells and Chinese medicine-derived cell lines. It has been found to be effective in inhibiting the growth of mutant cancer cells by blocking the activity of specific kinases. This inhibitor shows promise as a potential treatment for cancer and tumors due to its ability to target specific pathways involved in cancer progression.
Formula:C16H22N6O7Purity:Min. 95%Molecular weight:410.38 g/molFp-biotin-d4
CAS:Please enquire for more information about Fp-biotin-d4 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C27H50FN4O5PSPurity:Min. 95%Molecular weight:596.8 g/mol(±)-3',4'-Dihydro-1'-hydroxy-7'-methoxy-spiro[cyclopentane-1,2'(1'H)-naphthalene]-1'-acetonitrile
CAS:(±)-3',4'-Dihydro-1'-hydroxy-7'-methoxy-spiro[cyclopentane-1,2'(1'H)-naphthalene]-1'-acetonitrile is an impurity standard that is used as a research and development (R&D) chemical. It can be custom synthesized and is available as a drug product. This compound is synthetically derived and has high purity. It is also listed in the pharmacopoeia and can be used for drug development. Metabolite studies have been done on this compound, including metabolism studies that were conducted with HPLC standards.Formula:C17H21NO2Purity:Min. 95%Molecular weight:271.35 g/molN-Desisopropyl-N-formyl bisoprolol
CAS:N-Desisopropyl-N-formyl bisoprolol is a compound derived from chamomile extract that has various applications in the industrial sector. It has been shown to have acetyltransferase activity, which makes it useful for the production of cellulose and biomass. Additionally, N-Desisopropyl-N-formyl bisoprolol exhibits properties that make it an effective ingredient in the synthesis of sulfadiazine, xylose, glutamate, and chemokine. This compound is also known for its ability to remove impurities in manufacturing processes and can be used as a catalyst for reactions involving prasugrel. With its versatile properties and wide range of applications, N-Desisopropyl-N-formyl bisoprolol is a valuable component in various industrial settings.
Formula:C16H25NO5Purity:Min. 95%Molecular weight:311.37 g/molLoe 908 hydrochloride
CAS:Loe 908 hydrochloride is a cytosolic calcium ionophore with a biphasic response. It activates epidermal growth factor and inhibits myosin phosphatase, inhibiting the activation of the Ras pathway. Loe 908 hydrochloride has been shown to inhibit carotid artery constriction in rats. This drug acts by binding to cation channels in blood vessel walls, which prevents the influx of calcium ions into the cells of the vessel wall. Loe 908 hydrochloride also binds to 5-HT2 receptors and activates them. The result is an increase in intracellular calcium levels and inhibition of adenylyl cyclase, which leads to a decrease in cyclic AMP levels. This leads to decreased contractility in smooth muscle cells and relaxation of arterial smooth muscle cells.Formula:C41H49ClN2O9Purity:Min. 95%Molecular weight:749.3 g/molMm 77 dihydrochloride
CAS:Mm 77 is a blocker of serotonin. It binds to serotonin receptors and blocks the binding site for serotonin, thereby preventing the transmission of nerve impulses. Mm 77 has been shown to be effective in treating hepatitis.Formula:C19H29Cl2N3O3Purity:Min. 95%Molecular weight:418.4 g/mol(1RS)-1-(6-Methoxy-2-naphthyl)ethanol
CAS:(1RS)-1-(6-Methoxy-2-naphthyl)ethanol is a multiphase test drug that exhibits reactive properties. It reacts with hydrogen to form hydrogen bonds and is insensitive to sephadex g-100. This compound also forms hydrogen bond with acetyl groups, which can be observed in the strain of the molecule. (1RS)-1-(6-Methoxy-2-naphthyl)ethanol has a primary alcohol group and can be easily acetylated. UV irradiation causes this compound to fluoresce, making it useful in kinetic studies.Formula:C13H14O2Purity:Min. 95%Molecular weight:202.25 g/molDepyrazine 6,8-dinitrophenyl varenicline
CAS:Please enquire for more information about Depyrazine 6,8-dinitrophenyl varenicline including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C11H11N3O4Purity:Min. 95%Molecular weight:249.22 g/molAlisporivir intermediate-1
CAS:Alisporivir intermediate-1 is a drug product that is used for analytical and metabolism studies. It is a natural API impurity of Metabolism studies, CAS No. 882506-05-0, and has an Impurity standard of Synthetic. Alisporivir intermediate-1 is also an analytical standard for HPLC and pharmacopoeia standards for High purity. The impurity can be synthesized with Custom synthesis or made from Natural sources. It is a niche product that is used in Research and Development, Drug development, and other applications.
Formula:C74H132N12O17Purity:Min. 95%Molecular weight:1,461.9 g/mol5-Deoxy-Δ5,6-8-epi-tacrolimus
CAS:Please enquire for more information about 5-Deoxy-Δ5,6-8-epi-tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C44H67NO11Purity:Min. 95%Molecular weight:786 g/molo-Acetamidodiphenyl ether
CAS:Acetamidodiphenyl ether (AEP) is a toxic environmental chemical that is used in the manufacture of plastics, rubber and pesticides. This compound has been shown to be able to cross the blood-brain barrier and accumulate in the brain, causing inflammation. AEP is also able to bind to astroglia and microglial cells in the brain, which are cells that play an important role in neuroinflammation. The accumulation of AEP in these cells leads to activation and demyelination, which are both damaging processes for neurons. Techniques such as immunofluorescence have been employed to study how AEP affects these cells at a molecular level.Formula:C14H13NO2Purity:Min. 95%Molecular weight:227.26 g/mol3-Hydroxy-4-methoxycinnamic acid-d3 (isoferulic acid-d3)
CAS:3-Hydroxy-4-methoxycinnamic acid-d3 (isoferulic acid-d3) is a natural compound that belongs to the class of isoflavones. It is found in Cimicifuga foetida and has been shown to have anti-inflammatory and hypoglycemic effects. This compound has been found to scavenge anion radicals and inhibit signal pathways, such as MAPK and NF-κB, by binding to the Mcl-1 protein. Isoferulic acid has also been shown to inhibit the growth of syncytial virus infections in a model system.Formula:C10H10O4Purity:Min. 95%Molecular weight:197.2 g/mol4-Methylbenzylidene camphor-d4
CAS:4-Methylbenzylidene camphor-d4 is an analytical reference standard. It is used as a high purity drug development API impurity, HPLC standard, and CAS No. 1219806-41-3. 4-Methylbenzylidene camphor-d4 is also used in the manufacture of niche drug products that require Impurity standards and Metabolites.Formula:C18H18D4OPurity:Min. 95%Molecular weight:258.39 g/molIvacaftor carboxylic acid lactone
CAS:Ivacaftor is a drug product that is used for the treatment of cystic fibrosis. It is an active ingredient of Kalydeco, which is a combination therapy to treat cystic fibrosis. Ivacaftor is the first FDA-approved drug for the treatment of CF in patients with specific mutations. The metabolism of ivacaftor has been studied by analytical methods and it has been shown to have natural impurities. The API impurity and synthetic impurity standards are available for custom synthesis and can be ordered from a specialty manufacturer. Ivacaftor requires high purity and pharmacopoeia-grade standards for research and development as well as niche markets, such as HPLC standard or high purity.Formula:C24H24N2O4Purity:Min. 95%Molecular weight:404.5 g/molDr 4485 hydrochloride
CAS:Dr 4485 hydrochloride is a synthetic, semi-synthetic drug product that is used as an analytical reference material and in the development of drugs. Dr 4485 hydrochloride is also a metabolite of Dr 4485. The compound has been found to have natural origin from plants, but can also be synthetically made. It is not on the current USP/BP/EP monographs and does not have a CAS number. Dr 4485 hydrochloride has been shown to be metabolized through N-dealkylation, oxidation, and hydroxylation reactions. Dr 4485 hydrochloride may show various impurities that are related to the synthesis process or its metabolism. This compound has been studied for its ability to affect the growth of cancer cells via inhibition of protein synthesis by binding to ribosomes in the cytoplasmic membrane of cancer cells.Formula:C26H29Cl3N2OPurity:Min. 95%Molecular weight:491.9 g/mol6β-Hydroxy mometasone furoate
CAS:6β-Hydroxy mometasone furoate is a synthetic glucocorticoid that has high potency and receptor activity. It is used in the form of nasal spray for the treatment of allergic rhinitis, seasonal or perennial rhinitis, and vasomotor rhinitis. 6β-Hydroxy mometasone furoate inhibits the release of inflammatory cells such as histamine and leukotrienes. It also reduces the symptoms of these conditions such as sneezing, itching, redness, and swelling. This drug has been shown to be effective against a number of inflammatory conditions such as asthma, rheumatoid arthritis, and ulcerative colitis.Formula:C27H30Cl2O7Purity:Min. 95%Molecular weight:537.4 g/molDiamidafos
CAS:Diamidafos is a potent anticancer drug that has been used in Chinese traditional medicine to treat tumors. It acts as a protein kinase inhibitor, preventing the phosphorylation of proteins involved in cell growth and survival. Diamidafos is an analog of staurosporine, one of the first protein kinase inhibitors discovered. It has been shown to induce apoptosis in cancer cells by inhibiting the activity of various kinases. Diamidafos has also been found to inhibit the growth of human cancer cells and reduce tumor size in animal models. In addition, it can be administered orally and is excreted primarily through urine. To improve its efficacy, diamidafos can be combined with chitosan, a natural polymer that enhances drug delivery and bioavailability.Formula:C8H13N2O2PPurity:Min. 95%Molecular weight:200.17 g/molFlubendazole alcohol
CAS:Flubendazole alcohol is a drug product that is an impurity standard for the synthesis of flubendazole. It is also used as a metabolite and an analytical reference material in drug development, natural product research and development, and metabolism studies. Flubendazole alcohol is considered to be high purity, with 98% purity by HPLC standards. The CAS number for this product is 82050-12-2.Formula:C16H14FN3O3Purity:Min. 95%Molecular weight:315.3 g/mol
