APIs for research and impurities

<p>Decarbazolyl desmethyl carvedilol is a potent anticancer agent that inhibits elastase and protein kinases, which are involved in cancer cell growth and tumor progression. It induces apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of specific kinases. Decarbazolyl desmethyl carvedilol has been shown to be effective against a variety of human cancers, including lung, breast, and prostate cancers. It is also an inhibitor of Chinese hamster ovary (CHO) cell kinase activity and can be detected in urine samples. This analog of carvedilol has potential as a therapeutic agent for the treatment of cancer.</p>

<p>N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride is an impurity in the synthesis of N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N'-methylpropylenediamine formamide hydrochloride. It is a white solid that can be used as an analytical reference standard for HPLC. It has been detected in the urine of people taking this drug and can be used to identify the presence of this drug in urine samples.</p>

<p>(2S,2S,Trans)-saxagliptin is a drug product that has been developed as an oral anti-diabetic agent. It is a synthetic compound with the chemical name of (2S,2S,Trans)-4-[(1R)-1-[[(3Z)-3-(dimethylamino)-1-[(4-methylphenyl)sulfonyl]propanoyl]amino]-2-methylpropyl]-N-[4-(6-methoxy-3-pyridinyl)benzoyl]glycine. The synthesis of this drug is based on the natural amino acid sequence of the human insulin molecule. (2S,2S,Trans)-saxagliptin has been shown to be metabolized in vivo through hydroxylation and glucuronidation pathways and to have a half life of approximately 10 hours in humans. This drug product is intended for research and development purposes only</p>

<p>Please enquire for more information about Meclizine ortho chloro isomer bishydrochloride salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Boc-3-hydroxy-1-adamantyl-glycine is a catalytic, nucleophilic, chiral amino acid that is used in the synthesis of oximes. Boc-3-hydroxy-1-adamantyl-glycine has been shown to be an effective substitute for hydroxylamine in reductive amination reactions and can be used to synthesize some pharmaceuticals, including saxagliptin. This compound is stable under standard conditions and can be easily synthesized. It is also a powerful nucleophile that reacts with electrophiles such as chloroformates and sulfonyl chlorides.</p>

<p>Please enquire for more information about 2-(Diethylamino)ethyl 3-amino-4-ethoxybenzoate hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Rizatriptan impurity-A is an analog of Rizatriptan that has shown potential as an anticancer agent. It has been found in urine and has been studied for its ability to induce apoptosis in human cancer cells. This compound is a kinase inhibitor, which means it can inhibit the activity of specific proteins involved in cell replication and growth. As a result, it may be useful as a medicinal inhibitor for the treatment of various tumors and cancers. The research on Rizatriptan impurity-A is ongoing, but it shows promise as a potential new therapy for cancer patients.</p>

<p>6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone is a compound that is commonly used as an intermediate in the synthesis of various chemicals. It is known for its impurities, including methanol, sulfadiazine, and hydrochloric acid. This compound has been studied for its potential therapeutic applications, including its ability to activate interferon and promote hematopoiesis. Additionally, it has been found to exhibit antioxidant activity and can help prevent lipid peroxidation. 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone also shows promise as a photodegradation agent for certain herbicides and prasugrel. Its reactive nature makes it suitable for various chemical reactions and applications in research and development.</p>

<p>Please enquire for more information about Allyl ester of atorvastatin cyclic (isopropyl) impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Hygrine-d3 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,3,6,7-Tetrachlorobiphenylene is a potent inhibitor of kinases that are involved in cancer cell growth and proliferation. It is an analog of tolvaptan, a drug used to treat hyponatremia by increasing urine output. This compound has been shown to induce apoptosis in cancer cells and inhibit tumor growth. Studies have found that 2,3,6,7-Tetrachlorobiphenylene inhibits the activity of human protein kinases and may be effective against various types of cancer. This Chinese compound has promising anticancer properties and could potentially be used as a therapeutic agent for cancer treatment.</p>

<p>Erythromycin impurity K is a synthetic impurity of erythromycin, which is an antibiotic drug product. It is typically found in pharmaceutical products that are made from natural sources and is used as a research and development (R&amp;D) standard for the pharmacopoeia. Erythromycin impurity K can be purified by HPLC or other means to create high purity standards for analytical purposes. The chemical name of this compound is 3-[[[3-(2-Amino-4-thiazolyl)-1,2,4-triazol-5-yl]amino]methyl]-1H-indole.</p>

<p>Please enquire for more information about 4-Bromo-2-cyclobutylthiazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Rac-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine is an organic compound with the molecular formula C10H14N. Racemic rac-1,2,3,4-tetrahydro-5-methoxy-N propyl 2 naphthalenamine has been used in the synthesis of rotigotine. The enantiomers can be separated by means of an electrophoretic method. Racemic rac 1,2 3 4 tetrahydro 5 methoxy n propyl 2 naphthalenamine has a melting point range of 138 to 141 °C and a boiling point range of 285 to 288 °C at atmospheric pressure. This compound is soluble in organic solvents such as chloroform and ethanol and insoluble in water. It has a density of 1.07 g/cm3 at 20 °C and it is</p>

<p>Enrofloxacin impurity E is a product of the synthesis of enrofloxacin, with high purity and analytical standards. It is synthesized from natural products, and it can be used as an impurity standard for HPLC analysis. Enrofloxacin impurity E also has pharmacopoeia and CAS number 1369495-59-9. This substance is used in drug development and research to study metabolism.</p>

<p>N-Debenzoyl-N-hexanoylpaclitaxel (DHBPTx) is an analog of paclitaxel. It inhibits cell proliferation by binding to the diketone group at the C-10 position of baccatin III, which inhibits the synthesis of taxol and other natural products with a diketone group at this position. DHBPTx is effective against colorectal carcinoma cells in culture, but has not been tested in vivo. This drug has also been shown to be effective against breast cancer cells that express high levels of 10-deacetylase activity. It is metabolized into 10-deacetylbaccatin III, which binds to cellular protein kinase C and causes inhibition of mitosis and apoptosis. In addition, DHBPTx can be conjugated with other drugs such as doxorubicin or vincristine to increase their effectiveness.</p>

<p>5-Chloro-1,3-dihydro-1-methyl-3-phenyl-2H-benzimidazol-2-one is a synthetic impurity that may be found in drug products. It is used as an analytical standard and is metabolized to 5,5'-dichloroquinoline by hydrolysis of the acetal linkage. The metabolite 5,5'-dichloroquinoline has been shown to have antiplatelet effects in vitro and may contribute to the antithrombotic activity of the parent compound. This substance is not intended for clinical use.</p>

<p>S-Nitroso-N-propionyl-D,L-penicillamine is a nitric oxide donor that can be used in the treatment of locomotor activity and renal injury. It has been shown to inhibit protein synthesis and growth factor production by light exposure. This drug has also been used to treat infectious diseases such as tuberculosis, as well as autoimmune diseases like lupus and lymphoproliferative disorders such as leukemia. S-Nitroso-N-propionyl-D,L-penicillamine is also used for the prevention of postoperative kidney damage after ischemia reperfusion during surgery. The drug was found to reduce the levels of neutrophils, which are cells that are responsible for inflammation. There have been no reports on its potential carcinogenicity or mutagenicity.</p>

<p>8-Hydroxyacyclovir is an analog of acyclovir, a drug used to treat viral infections. It is a potent inhibitor of protein kinase and has been shown to induce apoptosis in cancer cells. This compound has anti-tumor activity and shows promise as an anticancer agent. In Chinese medicine, indirubin, which is structurally similar to 8-hydroxyacyclovir, has been used as an anticancer agent for centuries. 8-Hydroxyacyclovir inhibits the activity of kinases involved in cell division and growth, leading to the death of cancer cells. It has been detected in human urine after administration, making it a potential candidate for use as a therapeutic agent for cancer treatment.</p>

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