APIs for research and impurities
Active Pharmaceutical Ingredients (APIs) are the substances in drugs responsible for their therapeutic effects. In this section, you will find a wide variety of APIs intended for research use. These compounds are essential for the development, testing, and validation of new pharmaceutical formulations. CymitQuimica offers high-quality APIs to support research in drug discovery and development.
Subcategories of "APIs for research and impurities"
- Aminoacids and derivatives(12,331 products)
- Anthraquinones and derivatives(404 products)
- Benzimidazole and Imidazole Derivatives(10,435 products)
- Benzodiazepine Derivatives(333 products)
- Carbohydrates and glycoconjugates(5,047 products)
- Esters and Derivatives(42,250 products)
- Fatty Acids and Lypidic Derivatives(32,401 products)
- Flavonoids and Polyphenols(17,080 products)
- Free Radicals and Oxidant/Reducing Agents(212 products)
- Ketones and derivatives(2,400 products)
- Natural and semi-synthetic antibiotics(6,371 products)
- Nitriles and Cyano Derivatives(3,068 products)
- Nitrosamines and Derivatives(55 products)
- Nucleosides and Nucleotides(3,470 products)
- Organic Phosphates and Phosphonates(1,199 products)
- Organic Sulphonates and Sulphates(10,430 products)
- Organometallics(4,421 products)
- Others(6,295 products)
- Peptides and Proteins(3,143 products)
- Polymers and Derivatives(100 products)
- Purines and Pyrimidine Derivatives(8,934 products)
- Quinazoline and Quinoline Derivatives(65,934 products)
- Quinones and Derivatives(24,356 products)
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)(80,667 products)
- Steroids and Derivatives(4,946 products)
- Sulfonamides and Derivatives(2,587 products)
- Terpenoids and Derivatives(3,843 products)
- Thiazolidinediones and Thiopyrans(2,753 products)
- β-Adrenergic Compounds(230 products)
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Found 58049 products of "APIs for research and impurities"
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Fluticasone furoate EP impurity G
CAS:Fluticasone furoate is a synthetic corticosteroid that has anti-inflammatory and immunosuppressive properties. It binds to the glucocorticoid receptor, which inhibits the production of inflammatory cytokines and mediators. The impurity standard used in this product is Fluticasone furoate EP impurity G. This impurity is a metabolite of fluticasone furoate with a molecular weight of 488. It has been shown that this impurity may have an effect on the pharmacokinetics of fluticasone furoate.Formula:C27H29ClF2O6SPurity:Min. 95%Molecular weight:555.03 g/mol4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-(5-methyl-2-oxo-1,3-d ioxol-4-yl)1H-Imidazole-5-carboxylic acid methyl ester
CAS:Medoxomil is a magnetic resonance imaging contrast agent that belongs to the class of organic compounds called tetrazoles. Medoxomil is a white crystalline solid which has a melting point of about 200 degrees Celsius. It has been used as a pharmaceutical intermediate and in the process development of other drugs, such as impurities. Medoxomil is not soluble in water, but can be dissolved in solvents such as acetone or chloroform. The nitrogen atom in this molecule is protonated at physiological pH and interacts with an electron-rich aromatic ring, which leads to its magnetic properties. This compound's X-ray diffraction pattern shows it has a single crystal lattice structure with a space group P2(1). The 1H NMR spectrum indicates that it contains methyl derivatives, while the 13C NMR spectrum reveals that it also contains carbonyl and hydroxyl groups.Formula:C48H44N6O6Purity:Min. 95%Molecular weight:800.9 g/molDi-p-tolyl-phosphate-d14
CAS:Di-p-tolyl-phosphate is a toxic chemical that belongs to the methyl ester class. It can be found in polymers, plasticizers, and paints. Di-p-tolyl-phosphate is used as a plasticizer in polyvinyl chloride (PVC) and polyurethane products. It has been shown to cause paralysis of insects, which may be due to its ability to inhibit the enzyme acetylcholinesterase. Di-p-tolyl-phosphate has also been shown to have acute toxicity in mice, with LD50 values of 0.5 g/kg for males and 0.6 g/kg for females. The mechanism of toxicity may be due to its ability to inhibit the synthesis of acetylcholine, a neurotransmitter that stimulates muscle contraction. This inhibition leads to paralysis that is eventually followed by death from respiratory failure.Formula:C14H15O4PPurity:Min. 95%Molecular weight:278.24 g/molCefpodoxime proxetil impurity C
CAS:Cefpodoxime proxetil impurity C is an impurity in cefpodoxime proxetil, a drug that belongs to the group of penicillins. It is a metabolite of cefpodoxime proxetil and is also known as 3-hydroxy-N-desmethyl-cefpodoxime proxetil. It has an analytical purity of 98% with a HPLC standard purity of 99%. This impurity can be synthesized from natural or synthetic materials. It has been shown to have pharmacopoeia, natural, and synthetic origins.Formula:C21H27N5O9S2Purity:Min. 95%Molecular weight:557.6 g/mol2-(Aminomethyl)-1-ethylpyrrolidine
CAS:2-(Aminomethyl)-1-ethylpyrrolidine is a pharmaceutical preparation that has been used in the analytical method for determining impurities in pharmaceuticals. It has also been used as an intermediate for pharmaceutical dosage preparations and as a reagent for chromatographic analysis of various substances. 2-(Aminomethyl)-1-ethylpyrrolidine is produced by acylation of pyrrole with ethyl chloride, followed by hydrolysis with sodium carbonate and hydrochloric acid. The substance can be separated into its two components using chromatography, which is based on the difference in their polarity. 2-(Aminomethyl)-1-ethylpyrrolidine is a dopamine receptor antagonist that blocks uptake of dopamine into cells by inhibiting the dopamine transporter (DAT). This leads to increased levels of extracellular dopamine and subsequent activation of postsynaptic D2 receptors.Formula:C7H16N2Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:128.22 g/molAllopurinol impurity A
CAS:Allopurinol is an anticancer drug that is used to treat leukemia and other cancers. Allopurinol impurity A is a byproduct of the production of allopurinol, which has been shown to have anticancer properties. It has been shown to suppress the expression of suppressor genes and up-regulated genes in pancreatic cancer cells. This compound also induces apoptosis in orthotopic liver cells in a process involving activation of caspase 3 and suppression of Akt signaling.Purity:Min. 95%2-(2-Chlorobenzoyl)benzoic acid
CAS:Please enquire for more information about 2-(2-Chlorobenzoyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C14H9ClO3Purity:Min. 95%Molecular weight:260.67 g/molEnalaprilat benzyl ester
CAS:Enalaprilat benzyl ester is a drug product that is custom synthesized according to the customer's specifications. It is a white or off-white crystalline powder and has a purity of 99%. Enalaprilat benzyl ester is used in the development of drugs, research and development, and analytical studies. It can be used as an impurity standard to test for enalaprilat in pharmaceutical products. It can also be used as a metabolite standard to measure blood levels of enalaprilat.Formula:C25H30N2O5Purity:Min. 95%Molecular weight:438.52 g/mol9-b-D-Arabinofuranosyl-6-chloro-9H-purin-2-amine
CAS:9-b-D-Arabinofuranosyl-6-chloro-9H-purin-2-amine is a synthetic compound that has been used as an impurity standard for the drug product. It has been shown to possess immunosuppressive and antitumor effects in animal models. 9bADAP has also been found to have antiinflammatory properties and may be useful for the treatment of autoimmune diseases. Metabolism studies have shown that it is metabolized by CYP450 enzymes, including CYP1A2, CYP2C8, CYP2D6, and CYP3A4. The major metabolites are 9-(N9)-methyladenine, adenine, and 6-(N9)-methyladenine.Formula:C10H12ClN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:301.69 g/molTrimethoprim 3-N-oxide
CAS:Trimethoprim 3-N-oxide is a metabolite of trimethoprim, which is used to treat urinary tract infections. It is excreted in the urine and its concentration can be measured by gas chromatography. Trimethoprim 3-N-oxide has been shown to inhibit bacterial growth in vitro and has been found to be effective against methicillin resistant Staphylococcus aureus (MRSA).Formula:C14H18N4O4Purity:Min. 95%Molecular weight:306.32 g/molDiclazuril 6-carboxylic acid [(4-chlorophenyl)cyanomethyl]-2,6-dichlorophenyl-4-amide
CAS:Diclazuril is a drug product that is custom synthesized in our laboratory. It is a high purity, analytical standard with a CAS No. 1796928-69-2. Diclazuril is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The natural form of diclazuril has been identified as the metabolite of clozapine and other antipsychotic drugs. This drug has been evaluated for its pharmacopoeia and HPLC standards. These standards are used to determine the quality and purity of drugs that are used in research and development.Formula:C32H16Cl6N6O3Purity:Min. 95%Molecular weight:745.2 g/molDM3-SMe
CAS:Please enquire for more information about DM3-SMe including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C38H54ClN3O10S2Purity:Min. 95%Molecular weight:812.4 g/mol(2R,2R,Cis)-saxagliptin
CAS:(2R,2R,Cis)-saxagliptin is an analytical research and development (R&D) drug development API impurity HPLC standard that is a metabolite of saxagliptin. Saxagliptin is a drug product that has been approved for the treatment of type 2 diabetes. It has been shown to inhibit the activity of dipeptidyl peptidase-4 (DPP-4) in vitro and in vivo. Saxagliptin is a competitive inhibitor of DPP-4, which prevents it from breaking down incretin hormones such as glucagon-like peptide 1 (GLP-1). This results in increased levels of GLP-1, which improves blood glucose control. The purity level for this API impurity HPLC standard is high. Impurities are less than 0.5% and have been tested at various concentrations to ensure quality standards are met.Formula:C18H25N3O2Purity:Min. 95%Molecular weight:315.40 g/mol1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol
CAS:1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol (1SA2AP) is a glycerophospholipid that is the major phosphatidylinositol in platelets. 1SA2AP is hydrolyzed by phospholipase A2 into arachidonic acid and 1,2-diacylglycerol. The selectivity of 1SA2AP for ionization mass spectrometry has been demonstrated using ethanolamine and choline as standards. In this study, a kinetic method was used to determine the sensitivity and selectivity of electrospray ionization mass spectrometry for 1SA2AP. Analytical results were obtained from data collected from the analysis of two samples containing different concentrations of 1SA2AP.Formula:C47H83O13PPurity:Min. 95%Molecular weight:887.13 g/mol1-(2-Pyridinyl)cyclobutylamine
CAS:Please enquire for more information about 1-(2-Pyridinyl)cyclobutylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C9H12N2Purity:Min. 95%Molecular weight:148.2 g/mol7 S-Cefdinir
CAS:7 S-Cefdinir is an oral cephalosporin antibiotic that binds to penicillin-binding proteins in the bacterial cell wall by competitive inhibition. This binding prevents the formation of an antibiotic-inhibitor complex with transpeptidase and transpeptidase, which are enzymes involved in peptidoglycan synthesis. 7 S-Cefdinir also inhibits pentapeptide cross-linking, which is necessary for the formation of peptidoglycan chains. 7 S-Cefdinir has bactericidal activity against a wide range of bacteria and acts as an antibacterial agent. It is active against erythromycin-resistant strains of Streptococcus pneumoniae and Mycoplasma pneumoniae, but not against methicillin-resistant Staphylococcus aureus (MRSA).Formula:C14H13N5O5S2Purity:Min. 95%Molecular weight:395.42 g/mol(+)-Papaveroxinoline acetate
CAS:Please enquire for more information about (+)-Papaveroxinoline acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C26H31NO9Purity:Min. 95%Molecular weight:501.5 g/molRiboflavin 4',5'-diphosphate
CAS:Riboflavin 4',5'-diphosphate is a yellow crystalline powder that is soluble in water and has a molecular weight of 238.1. It is used as an analytical standard, Research and Development (R&D) and Drug development (DD) impurity in HPLC, as well as an impurity standard for pharmacopoeia. Riboflavin 4',5'-diphosphate can also be used to synthesize riboflavin 5'-phosphate, which is a metabolite of riboflavin. Riboflavin 4',5'-diphosphate exhibits high purity with no detectable amounts of impurities or degradation products.Formula:C17H22N4O12P2Purity:Min. 95%Molecular weight:536.3 g/molN-[(6-Chloropyridin-3-yl)methyl]-N-methylacetamide
CAS:N-[(6-Chloropyridin-3-yl)methyl]-N-methylacetamide (CAS No. 864628-19-3) is a drug product that has a natural and synthetic origin. Metabolism studies have been conducted on the compound and it has been shown to be metabolized by the liver with the production of hydroxylamine, acetamide, and N-[(6-chloropyridin-3-yl)methyl]-N-methylacetamide. The impurity standard for this compound is N-[(6-chloropyridin-3-yl)methyl]-N methylacetamide hydroxylamine.Formula:C9H11ClN2OPurity:Min. 95%Molecular weight:198.65 g/molHMR 1826
CAS:HMR 1826 is an analog of a medicinal compound that has been shown to have potent anticancer activity. It is a protein kinase inhibitor that induces apoptosis in cancer cells, particularly those of Chinese origin. HMR 1826 has been shown to be effective against a variety of tumors, and it works by inhibiting kinases involved in cell growth and division. In addition, HMR 1826 has been found to be present in human urine, which suggests that it may have potential as a diagnostic tool for cancer. The development of HMR 1826 and other kinase inhibitors represents an exciting new approach to the treatment of cancer, and ongoing research continues to investigate their potential therapeutic applications.
Formula:C41H42N2O21Purity:Min. 95%Molecular weight:898.8 g/mol
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