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APIs for research and impurities

APIs for research and impurities

Active Pharmaceutical Ingredients (APIs) are the substances in drugs responsible for their therapeutic effects. In this section, you will find a wide variety of APIs intended for research use. These compounds are essential for the development, testing, and validation of new pharmaceutical formulations. CymitQuimica offers high-quality APIs to support research in drug discovery and development.

Subcategories of "APIs for research and impurities"

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Found 57147 products of "APIs for research and impurities"

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  • CPI 0610

    CAS:

    CPI 0610 is a medicinal compound that acts as a potent inhibitor of protein phosphorylation. It has been shown to inhibit the cell cycle and promote apoptosis in Chinese hamster ovary cells. CPI 0610 is an effective inhibitor of kinase activity in cancer cells, leading to decreased tumor growth and increased survival rates. In preclinical studies, CPI 0610 has demonstrated efficacy against a wide range of cancers, including breast, prostate, and lung cancer. This inhibitor has also been shown to be effective in human cancer cell lines, making it a promising candidate for future cancer therapies.

    Formula:C20H18ClN3O3
    Purity:Min. 95%
    Molecular weight:383.8 g/mol

    Ref: 3D-VYC72614

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  • 2-(4-Formylphenyl)propionic acid - Racemic

    CAS:

    2-(4-Formylphenyl)propionic acid is a racemic mixture of 2-formylphenylacetic acid and 4-formylphenylacetic acid. This compound is used in the treatment of bacterial infections and inflammation. It is an organic solution that can be injected, administered orally, or applied topically. The 2-(4-formylphenyl)propionic acid has been shown to have anti-inflammatory properties, but also has side effects such as skin irritation when it is applied topically. This drug can also cause nausea, vomiting, and diarrhea when administered orally.

    Formula:C10H10O3
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:178.18 g/mol

    Ref: 3D-IF27430

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  • (R)-(+)-1,1,2-Triphenyl-1,2-ethanediol

    CAS:

    (R)-(+)-1,1,2-Triphenyl-1,2-ethanediol is a heterocyclic compound with a five-membered ring. It is chiral and has two stereogenic centers in its structure. This chemical can be prepared by the reaction of hexane with phosgene and oxygen atoms in the presence of silicon. The preparative method for the synthesis of (R)-(+)-1,1,2-triphenyl-1,2-ethanediol involves the use of chiral phosphonates to produce a mixture that contains just one enantiomer.

    Formula:C20H18O2
    Purity:Min. 95%
    Molecular weight:290.36 g/mol

    Ref: 3D-IT58095

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  • 6-Desmethyl-6-methylhydroxy etoricoxib N1-oxide

    CAS:

    6-Desmethyl-6-methylhydroxy etoricoxib N1-oxide is a high purity drug product. It is an analytical standard used in the study of metabolism and in the development of drugs. This compound has been custom synthesized for use as an impurity standard for HPLC analysis of etoricoxib. 6DMHETO was synthesized to be used as a drug development research and development tool for the pharmaceutical industry, specifically for niche markets such as herbal supplements and dietary supplements.

    Formula:C18H15ClN2O4S
    Purity:Min. 95%
    Molecular weight:390.80 g/mol

    Ref: 3D-VXA39408

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  • 6-o-Benzyl-4-dehydroxy-4-dimethylphenylsilyl entecavir

    CAS:
    6-o-Benzyl-4-dehydroxy-4-dimethylphenylsilyl entecavir is a synthetic drug product with an API impurity. It's an analytical standard for the metabolite 6-o-benzylidene-4,6-didehydroentecavir (CAS 649761-24-0), which is a natural metabolite of entecavir. The impurity standard is used in research and development to study the drug product's metabolism and to ensure that it meets pharmacopeia standards.
    Formula:C27H31N5O2Si
    Purity:Min. 95%
    Molecular weight:485.7 g/mol

    Ref: 3D-ZAB76124

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  • N-Formyl leurosine

    CAS:

    N-Formyl leurosine is an inhibitor of fatty acid synthesis. It has been shown to inhibit the growth of solid tumours in mice and rats, but not in dogs. The mechanism by which N-formyl leurosine inhibits tumour growth is unknown. This compound is a formylating agent, which means that it can be used to form an aldehyde group from formaldehyde. This group has been implicated in the antitumour activity of N-formyl leurosine.

    Formula:C46H54N4O10
    Purity:Min. 95%
    Molecular weight:822.94 g/mol

    Ref: 3D-IF23552

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  • Alpha-amino-4-octylbenzenebutanoic acid

    CAS:

    Alpha-amino-4-octylbenzenebutanoic acid is an impurity standard for pharmacopoeia and drug development. It is a synthetic compound that has been shown to be a metabolite of the muscle relaxant succinylcholine. Alpha-amino-4-octylbenzenebutanoic acid is a high purity, custom synthesis material and can be used as a reference or calibration standard in analytical techniques such as HPLC.

    Formula:C18H29NO2
    Purity:Min. 95%
    Molecular weight:291.40 g/mol

    Ref: 3D-WYA82019

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  • (E,Z)-Epalrestat methyl ester

    CAS:

    (E,Z)-Epalrestat methyl ester is a drug product that is custom-synthesized for research and development purposes. It is a natural metabolite of (E,Z)-epalrestat acid. The chemical name for this compound is 3-[(2-chlorophenyl)methyl]-N-(1H-indol-3-ylmethylene)malonamide. The molecular weight of this compound is 284.87 g/mol and it has an empirical formula of C24H27ClN2O2. It has been found to inhibit the activity of phosphodiesterase (PDE), which plays a role in the breakdown of cyclic nucleotides such as cAMP and cGMP. This product has high purity and analytical data that can be used for metabolism studies or clinical trials.

    Formula:C16H15NO3S2
    Purity:Min. 95%
    Molecular weight:333.43 g/mol

    Ref: 3D-HCB77570

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  • Erlotinib-3-vinyl hydrochloride

    CAS:

    Erlotinib-3-vinyl hydrochloride is a drug product that is used in the treatment of cancer, including non-small cell lung cancer. It is an impurity standard for HPLC and analytical testing. Erlotinib-3-vinyl hydrochloride is also used as an API impurity and metabolite in metabolism studies. Erlotinib-3-vinyl hydrochloride can be synthesized from 4-(4'-vinylphenoxy)butanal, which is a natural compound obtained from plants like apple trees. This synthetic process can be done by the reduction of 4-(4'-vinylphenoxy)butanal with sodium borohydride, followed by reaction with vinyl chloride. The compound is also found as a metabolite in humans after oral administration of erlotinib, which has been shown to inhibit protein synthesis and DNA synthesis.

    Formula:C22H26ClN3O4
    Purity:Min. 95%
    Molecular weight:431.9 g/mol

    Ref: 3D-ZPC29438

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  • Sacubitril methyl ester

    CAS:

    Sacubitril methyl ester is a drug product that belongs to the group of angiotensin receptor blockers. It is a prodrug that is metabolized in vivo to its active form, sacubitril. Sacubitril methyl ester has been shown to be effective in reducing morbidity and mortality in patients with chronic heart failure.

    Formula:C23H27NO5
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:397.47 g/mol

    Ref: 3D-IS181150

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  • N-Desbispropyl-N-pentyl-2-methyl ropinirole

    CAS:

    N-Desbispropyl-N-pentyl-2-methyl ropinirole is an analytical reference standard. This product is a high purity, drug development, and API impurity. It is a CAS No. 249622-60-4 and has a niche, drug product, and impurity standard. This item is for Research and Development, High purity, Drug development, API impurity, HPLC standard, CAS No. 249622-60-4, niche, drug product, Impurity standard, Metabolite, pharmacopoeia Custom synthesis of natural or synthetic origin.

    Formula:C16H24N2O
    Purity:Min. 95%
    Molecular weight:260.37 g/mol

    Ref: 3D-ZJA62260

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  • N-4,5[Acetylamino)methyl]desmopressin


    N-4,5[Acetylamino)methyl]desmopressin is a synthetic drug product that is used as an analytical standard for the identification and quantitation of desmopressin in pharmaceutical preparations. It is also used as an impurity standard for HPLC analysis. This product has been synthesized using a custom synthesis process, and has been shown to be suitable for use in drug development and research and development. N-4,5[Acetylamino)methyl]desmopressin is also available as a high purity HPLC standard that meets pharmacopoeia requirements.

    Purity:Min. 95%

    Ref: 3D-IA173214

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  • Mch-1 antagonist 1

    CAS:

    Mch-1 antagonist 1 is a drug product that is custom synthesized and is available in high purity. This compound is analytical, and it has been shown to be metabolized in vivo. Metabolism studies have been performed using this compound for the purposes of drug development. CAS No. 1039825-68-7 is the unique identification number for this compound, and it appears on the U.S. Drug Enforcement Administration's list of controlled substances as a natural product. It can be found in the pharmacopoeia as both a synthetic and natural product, with its synthetic form being an impurity standard for HPLC analysis. Mch-1 antagonist 1 has also been studied for its potential use in niche areas such as research and development of drugs or as an analytical standard for HPLC analysis.

    Formula:C25H26N4O2
    Purity:Min. 95%
    Molecular weight:414.5 g/mol

    Ref: 3D-PRB82568

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  • o-Desphenyl sofosbuvir

    CAS:

    o-Desphenyl sofosbuvir is a drug product that has been custom synthesized for research purposes. It is made of pure natural ingredients and does not contain any impurities. o-Desphenyl sofosbuvir is a metabolite from the synthesis of sofosbuvir, a drug used to treat hepatitis C. It can be used in pharmaceutical research and development as an analytical standard for HPLC.

    Formula:C16H25FN3O9P
    Purity:Min. 95%
    Molecular weight:453.36 g/mol

    Ref: 3D-IZB33582

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  • N-Desmethyl trimeprazine

    CAS:

    N-Desmethyl trimeprazine is a synthetic compound, which is an impurity of the drug product. It is not active and does not possess any biological activity. It is a metabolite of the parent drug, Trimeprazine. N-Desmethyl trimeprazine has been studied for its pharmacological properties and metabolism in the body, but no conclusive results have been found. The chemical structure and purity of N-Desmethyl trimeprazine are not listed in the USP or BP. This compound can be custom synthesized on request.

    Formula:C17H20N2S
    Purity:Min. 95%
    Molecular weight:284.40 g/mol

    Ref: 3D-XAA73204

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  • 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole

    CAS:

    2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].

    Formula:C15H15N3OS2
    Purity:Min. 95%
    Molecular weight:317.43 g/mol

    Ref: 3D-IM21229

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  • N’-(4-Acetylaminophenyl)-N,N-dimethylacetamidine

    CAS:
    N’-(4-Acetylaminophenyl)-N,N-dimethylacetamidine is a drug product that is used in the development of new drugs. It has high purity, analytical grade and natural origin. It is an impurity standard used in metabolite identification and research and development. The CAS number for this compound is 1358054-66-6.
    Formula:C12H17N3O
    Purity:Min. 95%
    Molecular weight:219.28 g/mol

    Ref: 3D-IEC05466

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  • Albendazole sulfone

    CAS:

    Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.

    Formula:C12H15N3O4S
    Purity:Min. 95 Area-%
    Color and Shape:Powder
    Molecular weight:297.33 g/mol

    Ref: 3D-IA17258

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  • 2-Methoxy-5-sulfamoylbenzoic acid

    CAS:

    2-Methoxy-5-sulfamoylbenzoic acid (2MSBA) is a reactive compound that reacts with the proton of vancomycin to form a dianion. This reaction is reversible and can be catalyzed by chloride ions. 2MSBA has been shown to be active against Staphylococcus, including MRSA strains, but not against Enterococci or Clostridium difficile. 2MSBA can be used in combination with cefepime or benzoate as an antibacterial agent. It also has antifungal properties, which may be due to its ability to inhibit the synthesis of ergosterol, an important component of fungal cell membranes.
    2-Methoxy-5-sulfamoylbenzoic acid is related to fluconazole in that it contains a benzoate moiety and an amide group. These structural features confer antibacterial and antif

    Formula:C8H9NO5S
    Purity:Min. 95%
    Molecular weight:231.23 g/mol

    Ref: 3D-IM145487

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  • 1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine

    CAS:

    1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine is a synthetic drug product. It is used as an analytical standard to help elucidate the metabolic pathway of drugs and their metabolites. This compound has been shown to be metabolized by various enzymes including CYP450, glutathione reductase, and esterases. It can also be synthesized from 1,4-dihydropyridine and 2-furancarboxaldehyde. The physical properties of 1,4-bis[(tetrahydro-2-furanyl)carbonyl]-piperazine are: white powder; mp 178°C; IR max 1710 cm−1 (CO); UV max 221 nm (EtOH). The impurities in this product are: 1-(2H)-Quinolinone (CAS No. 2467-94-1) which may have a maximum concentration

    Formula:C14H22N2O4
    Purity:Min. 95%
    Molecular weight:282.34 g/mol

    Ref: 3D-IB63853

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